Suppression of aromatase in human breast cells by a cyclooxygenase-2 inhibitor and its analog involves multiple mechanisms independent of cyclooxygenase-2 inhibition

Steroids

Volumn 73, Issue 1, 2008, Pages 104-111

  Su, Bin ^a   Díaz Cruz, Edgar S ^a   Landini, Serena ^a   Brueggemeier, Robert W ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

Aromatase; Breast cancer; Cyclooxygenase 2; NS 398; Prostaglandin E2

Indexed keywords

AROMATASE; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; DEXAMETHASONE; FORSKOLIN; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; N METHYL N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; PHORBOL ESTER; PROSTAGLANDIN E2; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; BREAST CELL; CANCER CELL CULTURE; CELL PROLIFERATION; CELL STRAIN MCF 7; CONTROLLED STUDY; CULTURE MEDIUM; DRUG MECHANISM; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REPRESSION; HUMAN; HUMAN CELL; MICROSOME; PLACENTA; PROTEIN EXPRESSION;

AROMATASE; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLOOXYGENASE 2 INHIBITORS; DEXAMETHASONE; FORSKOLIN; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INHIBITORY CONCENTRATION 50; MICROSOMES; MOLECULAR STRUCTURE; NITROBENZENES; PHORBOLS; SULFONAMIDES; TESTOSTERONE;

EID: 36849065197     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.steroids.2007.09.011     Document Type: Article

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