A steroidogenic factor-1-binding site and cyclic adenosine 3',5'- monophosphate response element-like elements are required for the activity of the rat aromatase promoter in rat Leydig tumor cell lines

Endocrinology

Volumn 139, Issue 12, 1998, Pages 5082-5093

  Young, Maureen ^a,b   Mcphaul, Michael J ^b  

^a JACKSON LABORATORY   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATASE; BINDING PROTEIN; CYCLIC AMP; CYTOCHROME P450; STEROIDOGENIC FACTOR 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL LINE; CYCLIC AMP RESPONSIVE ELEMENT; ENZYME ACTIVITY; LEYDIG CELL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; STEROIDOGENESIS; TRANSCRIPTION INITIATION;

EID: 0031723688     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.139.12.6377     Document Type: Article

References (48)

1. Valladares LE, Payne AH 1979 Induction of testicular aromatization by luteinizing hormone in mature rats. Endocrinology 105:431-436
2. Tsai-Morris C-H, Aquilano DR, Dufau ML 1985 Cellular localization of rat testicular aromatase activity during development. Endocrinology 116:38-46
3. Dorrington JR, Armstrong DT 1975 Folicle-stimulating hormone stimulates estradiol-17β synthesis in cultured Sertoli cells. Proc Natl Acad Sci USA 72:2677-2681
4. Nitta H, Bunick D, Hess RA, Janulis L, Newton SC, Millette CF, Osawa Y, Shizuta Y, Toda K, Bahr JM 1993 Germ cells of the mouse testis express P450 aromatase. Endocrinology 132:1396-1401
5. arom (aromatase) that catalyzes the formation of estrogen from androgen. J Biol Chem 263:16358-16363
6. Lephart ED, Peterson KG, Noble JF, George FW, McPhaul MJ 1990 The structure of cDNA clones encoding the aromatase P-450 isolated from a rat Leydig cell tumor line demonstrates different processing of aromatase mRNA in rat ovary and a neoplastic cell line. Mol Cell Endocrinol 70:31-40
7. Milewich L, George FW, Wilson JD 1977 Estrogen formation by the ovary of the rabbit embryo. Endocrinology 100:187-196
8. Naftolin F, Ryan KJ, Davies IJ, Reddy VV, Flores F, Petro Z, Kuhn M, White RJ, Takaoka Y, Wolin L 1975 The formation of estrogens by central neuroendocrine tissues. Recent Prog Horm Res 31:295-314
9. Yamada NM, Hirata S, Kato J 1994 Distribution and postnatal changes of aromatase mRNA in the female rat brain. J Steroid Biochem Mol Biol 48:529-533
10. Bolt HM, Gobel P 1972 Formation of estrogens from androgens by human subcutaneous adipose tissue in vitro. Horm Metab Res 4:312-313
11. Ryan KJ 1959 Biological aromatization of steroids. J Biol Chem 234:268-272
12. Simpson ER, Cleland WH, Mendelson CR 1983 Aromatization of androgens by human adipose tissue in vitro. J Steroid Biochem 19:707-719
13. McPhaul MJ, Herbst MA, Matsumine H, Young M, Lephart ED 1993 Diverse mechanisms of control of aromatase gene expression. J Steroid Biochem Mol Biol 44:341-346
14. Conley AJ, Corbin CJ, Hinshelwood MM, Liu Z, Simpson ER, Ford JJ, Harada N 1996 Functional aromatase expression in porcine adrenal gland and testis. Biol Reprod 54:497-505
15. Corbin CJ, Khalil MW, Conley AJ 1996 Functional ovarian and placental isoforms of porcine aromatase. Mol Cell Endocrinol 113:29-37
16. Choi I, Simmen RC, Simmen FA 1996 Molecular cloning of cytochrome P450 aromatase complementary deoxyribonucleic acid from periimplantation porcine and equine blastocysts identifies multiple novel 5′-untranslated exons expressed in embryos, endometrium, and placenta. Endocrinology 137:1457-1467
17. Bulun SE, Simpson ER 1994 Regulation of aromatase expression in human tissues. Breast Cancer Res Treat 30:19-29
18. Matsumine H, Herbst MA, Ou S-HI, Wilson JD, McPhaul MJ 1991 Aromatase mRNA in the extragonadal tissues of chickens with the henny-feathering trait is derived from a distinctive promoter structure that contains a segment of a retroviral long terminal repeat. J Biol Chem 266:19900-19907
19. Lephart ED, Herbst MA, McPhaul MJ 1995 Characterization of aromatase cytochome P-450 mRNA in rat perinatal brain, ovary, and a Leydig tumor cell line: evidence for the existence of brain specific aromatase transcripts. Endocrine 3:25-31
20. Hinshelwood MM, Corbin CJ, Tsang PCW, Simpson ER 1993 Isolation and characterization of a complementary deoxyribonucleotide acid insert encoding bovine aromatase cytochrome P450. Endocrinology 133:1971-1977
21. Vanselow J, Furbass R 1995 Novel aromatase transcripts from bovine placenta contain repeated sequence motifs. Gene 154:281-291
22. Young M, McPhaul MJ, Lephart ED 1997 The expression of aromatase cytochrome P-450 in rat H540 Leydig tumor cells. J Steroid Biochem Mol Biol 63:37-44
23. Steinkampf MP, Mendelson CR, Simpson ER 1987 Regulation by folliclestimulating hormone of the synthesis of aromatase cy tochrome P-450 in human granulosa cells. Mol Endocrinol 1:465-471
24. Fitzpatrick SL, Richards JS 1993 cis-acting elements of the rat aromatase promoter required for cyclic adenosine 3′,5′-monophosphate induction in ovarian granulosa cells and constitutive expression in R2C Leydig cells. Mol Endocrinol 7:341-354
25. Fitzpatrick SL, Richards JS 1994 Identification of a cyclic adenosine 3′,5′-monophosphate-response element in the rat aromatase promoter that is required for transcriptional activation in rat granulosa cells and R2C Leydig cells. Mol Endocrinol 8:1309-1319
26. Carlone DL, Richards JS 1997 Functional interactions, phosphorylation, and levels of 3′,5′-cyclic adenosine monophosphate-regulatory element binding protein and steroidogenic factor-1 mediate hormone-regulated and constitutive expression of aromatase in gonadal cells. Mol Endocrinol 11:292-304
27. Valladares LE, Payne AH 1981 Effects of hCG and cyclic AMP on aromatization in purified Leydig cells of immature and mature rats. Biol Reprod 35:752-758
28. Payne AH, Youngblood GL 1995 Regulation of expression of steroidogenic enzymes in Leydig cells. Biol Reprod 52:217-225
29. Lala DS, Rice DA, Parker KL 1992 Steroidogenic factor 1, a key regulator of steroidogenic enzyme expression, is the mouse homolog of fushi tarazu-factor I. Mol Endocrinol 6:1249-1258
30. Honda S-I, Morohashi K-I, Nomura M, Takeya H, Kitajima M, Omura T 1993 Ad4BP regulating steroidogenic P-450 gene is a member of steroid hormone receptor superfamily. J Biol Chem 268:7494-7502
31. Lynch JP, Lala DS, Peluso JJ, Luo W, Parker KL, White BA 1993 Steroidogenic factor 1, and orphan nuclear receptor, regulates the expression of the rat aromatase gene in gonadal tissues. Mol Endocrinol 7:776-786
32. Morohashi K-I, Zanger UM, Honda S-I, Hara M, Waterman MR, Omura T 1993 Activation of CYP11A and CYP11B gene promoters by the steroidogenic cell-specific transcription factor, Ad4BP. Mol Endocrinol 7:1196-1204
33. Leshin M, Noble JF 1986 Solubilization and partial purification of aromatase from chicken ovary. J Steroid Biochem 25:91-97
34. Lephart ED, Simpson ER 1991 Assay of aromatase activity. Methods Enzymol 206:477-483
35. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ 1951 Protein measurement with the Folin phenol reagent. J Biol Chem 193:265-275
36. Sanger F, Nicklens S, Coulson AR 1977 DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci USA 74:5463
37. Landolfi NF, Yin XM, Capra JD, Tucker PW 1988 A conserved heptamer upstream of the IgH promoter region octamer can be the site of a coordinate protein-DNA interaction. Nucleic Acids Res 16:5503-5514
38. Landolfi NF, Capra JD, Tucker PW 1987 Protein-nucleotide contacts in the immunoglobulin heavy-chain promoter region. Proc Natl Acad Sci USA 84:3851-3855
39. Michael LF, Alcom JL, Gao E, Mendelson CR 1996 Characterization of the cyclic adenosine 3′,5′-monophosphate response element of the rabbit surfactant protein-A gene: evidence for transactivators distinct from CREB/ATF family members. Mol Endocrinol 10:159-170
40. Shin S-I, Yasumura Y, Sato GH 1968 Studies on interstitial cells in tissue culture. II. Steroid biosynthesis by a clonal line of rat testicular interstitial cells. Endocrinology 82:614-616
41. Jacobs BB, Huseby RA 1967 Neoplasms occurring in aged Fischer rats, with special reference to testicular, uterine, and thyroid tumors. J Natl Cancer Inst 39:303-309
42. Ikeda Y, Lala DS, Luo X, Kim E, Moisan M-P, Parker KL 1993 Characterization of the mouse FTZ-F1 gene, which encodes a key regulator of steroid hydroxylase gene expression. Mol Endocrinol 7:852-860
43. Clemens JW, Lala DS, Parker KL, Richards JS 1994 Steroidogenic factor-1 binding and transcriptional activity of the cholesterol side-chain cleavage promoter in rat granulosa cells. Endocrinology 134:1499-1508
44. Shen W-H, Moore CCD, Ikeda Y, Parker KL, Ingraham HA 1994 Nuclear receptor steroidogenic factor 1 regulates the Mullerian inhibiting substance gene: a link to the sex determination cascade. Cell 77:651-661
45. Liu Z, Simpson ER 1997 Steroidogenic factor 1 (SF-1) and SP1are required for regulation of bovine CYP11A gene expression in bovine luteal cells and adrenal Y1 cells. Mol Endocrinol 11:127-137
46. Deutsch PJ, Hoeffler JP, Jameson JL, Lin JC, Habener JF 1988 Cyclic AMP and phorbol ester-stimulated transcription mediated by similar DNA elements that bind distinct proteins. Proc Natl Acad Sci USA 85:7922-7926
47. Deutsch PJ, Hoeffler JP, Jameson JL, Lin JC, Habener JF 1988 Structural determinants for transcriptional activiation by cAMP-responsive DNA elements. J Biol Chem 263:18466-18472
48. Meyer TE, Habener JF 1993 Cyclic adenosine 3′,5′-monophosphate response element binding protein (CREB) and related transcription-activating deoxyribonucleic acid-binding proteins. Endocr Rev 14:269-290