Matrix-assisted laser desorption/ionization imaging mass spectrometry for the investigation of proteins and peptides

Annual Review of Analytical Chemistry

Volumn 1, Issue 1, 2008, Pages 689-705

  Burnum, Kristin E ^a   Frappier, Sara L ^a   Caprioli, Richard M ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Imaging; MALDI; Mass spectrometry; Peptides; Proteins

Indexed keywords

DATA DIMENSIONALITY; DRUG ADMINISTRATION; FUTURE CHALLENGES; HIGH RESOLUTION IMAGE; IMAGING; IMAGING MASS SPECTROMETRY; MALDI; MALDI-MASS SPECTROMETRY; MATRIX; MATRIX ASSISTED LASER DESORPTION/IONIZATION; MOLECULAR DATA; MOLECULAR IMAGING; MOUSE EMBRYOS; NEURODEGENERATION; OPERATING PROCEDURES; REPRODUCIBILITIES; SAMPLE PREPARATION METHODS; SPERM MATURATION; THREE DIMENSIONAL IMAGING; TUMOR FORMATION;

DESORPTION; IMAGE ANALYSIS; MASS SPECTROMETERS; MATRIX ALGEBRA; MEDICAL APPLICATIONS; PEPTIDES; SECONDARY ION MASS SPECTROMETRY; SPECTROMETRY; THREE DIMENSIONAL;

MEDICAL IMAGING;

PEPTIDE; PROTEIN; PROTEOME;

ANIMAL; BIOLOGY; BRAIN; CHEMICAL ANALYSIS; CHEMISTRY; DEGENERATIVE DISEASE; FEMALE; HUMAN; INSTRUMENTATION; MALE; MASS SPECTROMETRY; METHODOLOGY; MOUSE; PATHOLOGY; PROTEOMICS; REVIEW;

ANIMALS; BIOLOGY; BRAIN; CHEMISTRY TECHNIQUES, ANALYTICAL; FEMALE; HUMANS; MALE; MICE; NEURODEGENERATIVE DISEASES; PEPTIDES; PROTEINS; PROTEOME; PROTEOMICS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 70350356597     PISSN: 19361327     EISSN: 19361335     Source Type: Book Series    
DOI: 10.1146/annurev.anchem.1.031207.112841     Document Type: Review

References (51)

1. Marko-Varga G, Fehniger TE. 2004. Proteomics and disease: the challenges for technology and discovery. J. Proteome Res. 3:167-178
2. Oehr P. 2006. 'Omics'-based imaging in cancer detection and therapy. Pers. Med. 3:19-32
3. Lescuyer P, Hochstrasser D, Rabilloud T. 2007.Howshall we use the proteomics toolbox for biomarker discovery? J. Proteome Res. 6:3371-3376
4. Lewin DA,Weiner MP. 2004. Molecular biomarkers in drug development. Drug Discov. Today 9:976-983
5. Bieck PR, Potter WZ. 2005. Biomarkers in psychotropic drug development: integration of data across multiple domains. Annu. Rev. Pharmacol. Toxicol. 45:227-246
6. Strand KJ, Khalak H, Strovel JW, Ebner R, Augustus M. 2006. Expression biomarkers for clinical efficacy and outcome prediction in cancer. Pharmacogenomics 7:105-115
7. Pusch W, Flocco MT, Leung SM, Thiele H, Kostrzewa M. 2003. Mass spectrometry-based clinical proteomics. Pharmacogenomics 4:463-476
8. Scaros O, Fisler R. 2005. Biomarker technology roundup: From discovery to clinical applications, a broad set of tools is required to translate from the lab to the clinic. Biotechniques 38:S30-S32
9. Kamb A, Wee S, Lengauer C. 2007. Opinion: Why is cancer drug discovery so difficult? Nat. Rev. Drug Discov. 6:115-120
10. Dass C. 2001. Principles and Practice of Biological Mass Spectrometry. New York: Wiley
11. Schwartz SA, Reyzer ML, Caprioli RM. 2003. Direct tissue analysis using matrixassisted laser desorption/ionization mass spectrometry: practical aspects of sample preparation. J. Mass Spectrom. 38:699-708
12. Johnson MD, Floyd JL, Caprioli RM. 2006. Proteomics in diagnostic neuropathology. J. Neuropathol. Exp. Neurol. 65:837-845
13. Chaurand P, Schwartz SA, Caprioli RM. 2004. Profiling and imaging proteins in tissue sections by MS. Anal. Chem. 76:86A-93A
14. Chaurand P, Schwartz SA, Billheimer D, Xu BGJ, Crecelius A, Caprioli RM. 2004. Integrating histology and imaging mass spectrometry. Anal. Chem. 76:1145-1155
15. Aerni HR, Cornett DS, Caprioli RM. 2006. Automated acoustic matrix deposition for MALDI sample preparation. Anal. Chem. 78:827-834
16. Groseclose MR, Andersson M, HardestyWM,Caprioli RM. 2007. Identification of proteins directly from tissue: in situ tryptic digestions coupled with imaging mass spectrometry. J. Mass Spectrom. 42:254-262
17. Baluya DL, Garrett TJ, Yost RA. 2007. Automated MALDI matrix deposition method with inkjet printing for imaging mass spectrometry. Anal. Chem. 79:6862-6867
18. Guo J. 2005. Discovery of biomarkers for endometrial carcinoma by direct profiling of proteins in tissue sections. Presented at Annu. Am. Soc. Mass Spectrom., 53rd, San Antonio, TX
19. Schuerenberg M, Luebbert C, Deininger S-O, Ketterlinus R, Detlev, Suckau D. 2007. MALDI tissue imaging: mass spectrometric localization of biomarkers in tissue slices. Nat. Methods 4:iii
20. Nye GJ, Norris JL, Nickerson S. 2006. Optimization of the performance of automated matrix spraying forMALDIimaging mass spectrometry. Presented at Annu. Am. Soc. Mass Spectrom., 54th, Seattle,WA
21. Mamyrin BA. 1994. Laser-assisted reflectron time-of-flight mass spectrometry. Int. J. Mass Spectrom. Ion Process. 131:1-19
22. Khatib-Shahidi S, Andersson M, Herman JL, Gillespie TA, Caprioli RM. 2006. Direct molecular analysis of whole-body animal tissue sections by imaging MALDI mass spectrometry. Anal. Chem. 78:6448-6456
23. Li Y, Shrestha B, Vertes A. 2007. Atmospheric pressure molecular imaging by infrared MALDI mass spectrometry. Anal. Chem. 79:523-532
24. McLean JA, Ridenour WB, Caprioli RM. 2007. Profiling and imaging of tissues by imaging ion mobility-mass spectrometry. J. Mass Spectrom. 42:1099-1105
25. Taban IM, Altelaar AFM, Van der Burgt YEM, McDonnell LA, Heeren RMA, et al. 2007. Imaging of peptides in the rat brain using MALDI-FTICR mass spectrometry. J. Am. Soc. Mass Spectrom. 18:145-151
26. Altelaar AFM, Taban IM, McDonnell LA, Verhaert P, de Lange RPJ, et al. 2007. High-resolution MALDI imaging mass spectrometry allows localization of peptide distributions at cellular length scales in pituitary tissue sections. Int. J. Mass Spectrom. 260:203-211
27. Verhaert PD, Conaway MCP, Pekar TM, Miller K. 2007. Neuropeptide imaging on an LTQ with vMALDI source: the complete 'all-in-one' peptidome analysis. Int. J. Mass Spectrom. 260:177-184
28. DeKeyser SS, Kutz-Naber KK, Schmidt JJ, Barrett-Wilt GA, Li LJ. 2007. Imaging mass spectrometry of neuropeptides in decapod crustacean neuronal tissues. J. Proteome Res. 6:1782-1791
29. Norris JL, Cornett DS, Mobley JA, Andersson M, Seeley EH, et al. 2007. Processing MALDI mass spectra to improve mass spectral direct tissue analysis. Int. J. Mass Spectrom. 260:212-221
30. Jolliffe IT. 2002. Principal Component Analysis. New York: Springer-Verlag
31. Tusher VG, Tibshirani R, Chu G. 2001. Significance analysis of microarrays applied to the ionizing radiation response. Proc. Natl. Acad. Sci. 98:5116-5121
32. Meunier B, Dumas E, Piec I, Bechet D, Hebraud M, Hocquette J-F. 2006. Assessment of hierarchical clustering methodologies for proteomic data mining. J. Proteome Res. 6:358-366
33. Hanahan D,Weinberg RA. 2000. The hallmarks of cancer. Cell 100:57-70
34. Stoeckli M, Chaurand P, Hallahan DE, Caprioli RM. 2001. Imaging mass spectrometry: a new technology for the analysis of protein expression in mammalian tissues. Nat. Med. 7:493-496
35. Reyzer ML, Caldwell RL, Dugger TC, Forbes JT, Ritter CA, et al. 2004. Early changes in protein expression detected by mass spectrometry predict tumor response to molecular therapeutics. Cancer Res. 64:9093-9100
36. Chaurand P, Sanders ME, Jensen RA, Caprioli RM. 2004. Proteomics in diagnostic pathology: profiling and imaging proteins directly in tissue sections. Am. J. Pathol. 165:1057-1068
37. Schwamborn K, Krieg RC, Reska M, Jakse G, Knuechel R,Wellmann A. 2007. Identifying prostate carcinoma by MALDI-imaging. Int. J. Mol. Med. 20:155-159
38. Crecelius AC, Cornett DS, Caprioli RM,Williams B, Dawant BM, Bodenheimer B. 2005. Three-dimensional visualization of protein expression in mouse brain structures using imaging mass spectrometry. J. Am. Soc. Mass Spectrom. 16:1093-1099
39. Andersson M, Groseclose MR, Deutch AY, Caprioli RM. 2008. Imaging mass spectrometry of proteins and peptides: 3D volume reconstruction. Nature Methods 5:101-108
40. Haacke EM, Brown RW, Thompson ML, Venkatesan R. 1999. Magnetic Resonance Imaging: Physical Principles and Sequence Design. New York:Wiley
41. Sinha TK, Khatib-Shahidi S, Yankeelov TE, Mapara K, Ehtesham M, et al. 2008. Integrating spatially resolved three-dimensional MALDI IMS with in vivo magnetic resonance imaging. Nature Methods 5:57-59
42. Ingelsson M, Fukumoto H, Newell KL, Growdon JH, Hedley-Whyte ET, et al. 2004. Early Aβ accumulation and progressive synaptic loss, gliosis, and tangle formation in AD brain. Neurology 62:925-931
43. Schonheit B, Zarski R, Ohm TG. 2004. Spatial and temporal relationships between plaques and tangles in Alzheimer pathology. Neurobiol. Aging 25:697-711
44. Rohner TC, Staab D, Stoeckli M. 2005. MALDI mass spectrometric imaging of biological tissue sections. Mech. Ageing Dev. 126:177-185
45. Skold K, Svensson M, Nilsson A, Zhang XQ, Nydahl K, et al. 2006. Decreased striatal levels of PEP-19 following MPTP lesion in the mouse. J. Proteome Res. 5:262-269
46. Chaurand P, Fouchécourt S, DaGue BB, Xu BJ, Reyzer ML, et al. 2003. Profiling and imaging proteins in the mouse epididymis by imaging mass spectrometry. Proteomics 3:2221-2239
47. Walgren JL, Thompson DC. 2004. Application of proteomic technologies in the drug development process. Toxicol. Lett. 149:377-385
48. Rudin M, Rausch M, Stoeckli M. 2005. Molecular imaging in drug discovery and development: potential and limitations of nonnuclear methods. Mol. Imag. Biol. 7:5-13
49. Hsieh Y, Chen J, Korfmacher WA. 2007. Mapping pharmaceuticals in tissues using MALDI imaging mass spectrometry. J. Pharmacol. Toxicol. Methods 55:193-200
50. Meistermann H, Norris JL, Aerni H-R, Cornett DS, Friedlein A, et al. 2006. Biomarker discovery by imaging mass spectrometry:Transthyretin is a biomarker for gentamicin-induced nephrotoxicity in rat. Mol. Cell Proteomics M500399-200
51. Lemaire R, Desmons A,Tabet JC, Day R, Salzet M, Fournier I. 2007. Direct analysis and MALDI imaging of formalin-fixed, paraffin-embedded tissue sections. J. Proteome Res. 6:1295-1305