Protective effects of saponins from the root of Platycodon grandiflorum against fatty liver in chronic ethanol feeding via the activation of AMP-dependent protein kinase

Food and Chemical Toxicology

Volumn 47, Issue 11, 2009, Pages 2749-2754

  Khanal, Tilak ^a   Choi, Jae Ho ^a   Hwang, Yong Pil ^a   Chung, Young Chul ^b   Jeong, Hye Gwang ^a,c  

^a Chosun University   (South Korea)

^b Jinju International University   (South Korea)

^c Chungnam National University   (South Korea)

Author keywords

ACC; Alcoholic steatosis; AMPK; Platycodon grandiflorum

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; ALANINE AMINOTRANSFERASE; ALBUMIN; ALCOHOL; ASPARTATE AMINOTRANSFERASE; CYTOCHROME P450 2E1; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; SAPONIN; TRIACYLGLYCEROL;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALBUMIN BLOOD LEVEL; ALCOHOL CONSUMPTION; ALCOHOLIC FATTY LIVER; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; DISEASE MODEL; DRUG DOSE COMPARISON; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME PHOSPHORYLATION; FOOD INTAKE; LIVER PROTECTION; MALE; NONHUMAN; PLANT ROOT; PLATYCODON; PLATYCODON GRANDIFLORUM; PROTEIN EXPRESSION; RAT; TREATMENT DURATION;

ANIMALS; CYTOCHROME P-450 CYP2E1; ENZYME ACTIVATION; FATTY LIVER, ALCOHOLIC; GENE EXPRESSION REGULATION, ENZYMOLOGIC; MALE; PHOSPHORYLATION; PHOSPHOTRANSFERASES (PHOSPHATE GROUP ACCEPTOR); PLANT ROOTS; PLATYCODON; RATS; RATS, SPRAGUE-DAWLEY; SAPONINS;

PLATYCODON GRANDIFLORUM; RATTUS;

EID: 70350207181     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2009.08.006     Document Type: Article

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