Influence of perfusate composition on drug disposition in the in-situ perfused rat lung

International Journal of Pharmaceutics

Volumn 382, Issue 1-2, 2009, Pages 192-197

  Liu, Xin ^a   Wang, Jimmy Yujia ^a   Khlentzos, Alexander M ^a   Fontaine, Frank ^a   Nikolovski, Julijana ^a   Goh, Lee Ann ^a   Roberts, Michael S ^a,b  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b UNIVERSITY OF SOUTH AUSTRALIA   (Australia)

Author keywords

Bovine serum albumin; Dextran; In situ lung perfusion; Physiological pharmacokinetics

Indexed keywords

ATENOLOL; BOVINE SERUM ALBUMIN; DEXTRAN; PROPRANOLOL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DILUTION; DRUG DETERMINATION; DRUG DISPOSITION; DRUG PENETRATION; LUNG PERFUSION; MALE; NONHUMAN; ONCOTIC PRESSURE; PRIORITY JOURNAL; RAT;

ANIMALS; ANTIPYRINE; ATENOLOL; BUFFERS; CARBON RADIOISOTOPES; DEUTERIUM OXIDE; DEXTRANS; EVANS BLUE; HYDROGEN-ION CONCENTRATION; INDICATOR DILUTION TECHNIQUES; LUNG; MALE; MODELS, BIOLOGICAL; MORPHOLINES; PERFUSION; PERMEABILITY; PRESSURE; PROPRANOLOL; RATS; RATS, WISTAR; SERUM ALBUMIN, BOVINE; SUCROSE;

EID: 70350183750     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2009.08.028     Document Type: Article

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