The production of eicosapentaenoic acid by representatives of the genus Mortierella grown on brewers' spent grain

Biologia

Volumn 64, Issue 5, 2009, Pages 871-876

  Jacobs, Annali ^a   Botha, Alf ^b   van Zyl, Willem H ^b  

^a DSI CSIR Nanotechnology Innovation Centre   (South Africa)

^b STELLENBOSCH UNIVERSITY   (South Africa)

Author keywords

Eicosapentaenoic acid; HUFA; Linseed oil; Mortierella; Spent grain

Indexed keywords

EPICLADIA; MORTIERELLA;

EID: 70350144467     PISSN: 00063088     EISSN: 13369563     Source Type: Journal    
DOI: 10.2478/s11756-009-0152-1     Document Type: Article

References (24)

1. Bajpaj P., Bajpaj P.K. & Ward O.P. 1991. Effects of aging Mortierella mycelium on production of arachidonic and eicosapentaenoic acids. J. Am. Oil Chem. Soc. 68: 775-780.
2. Cavalier-Smith T. 1998. A revised six-kingdom system of life. Biol. Rev. 73: 203-266.
3. Certik M. & Shimuzu S. 1999. Biosynthesis and regulation of microbial polyunsaturated fatty acid production. J. Biosci. Bioeng. 87: 1-14.
4. Cheng M.H., Walker T.H., Hulbert G.J. & Raman D.R. 1999. Fungal production of eicosapentaenoic and arachidonic acid from industrial waste streams and crude soybean oil. Biores. Technol. 67: 101-110.
5. Cohen Z. & Ratledge C. 2005. Single Cell Oils. AOCS Press, Champaign, Illinois, ISBN 1-893997-80-4, 257 pp.
6. Conti E., Stredansky M., Stredanska S. & Zanetti F. 2001. γ-Linolenic acid production by solid-state fermentation of Mucorales strains on cereals. Biores. Technol. 76: 283-286.
7. Dyal S. & Narine S.S. 2005. Implications of the use of Mortierella fungi in the industrial production of essential fatty acids. Food. Res. Int. 38: 445-467.
8. Dyal S., Bouzidi L. & Narine S.S. 2005. Maximising the production of γ-linolenic acid in of Mortierella ramanniana var. ramanniana as a function of pH, temperature and carbon source, nitrogen source, metal ions and oil supplementation. Food. Res. Int. 38: 815-829.
9. Emelyanova E.V. 1996. γ-Linolenic acid production by Cunninghamella japonica in solid state fermentation. Process Biochem. 31: 431-434.
10. Folch J., Lees M. & Sloane Stawley G.H. 1957. A simple method for the isolation and purification of total lipides from animal tissues. J. Biol. Chem. 226: 497-509.
11. Higashiyama K., Fujikawa S., Park E.Y. & Okabe M. 1999. Image analysis of morphological change during arachidonic acid production by Mortierella alpina 1S-4. J. Biosci. Bioeng. 87: 489-494.
12. Higashiyama K., Fujikawa S., Park E.Y. & Shimuzu S. 2002. Production of arachidonic acid by Mortierella fungi. Biotechnol. Proc. Eng. 7: 252-262.
13. Jang H.D., Lin Y.Y. & Yang S.S. 2000. Polyunsaturated fatty acid production with Mortierella alpina by solid state fermentation. Bot. Bull. Acad. Sin. 41: 41-48.
14. Koike Y., Cai H.J., Higashiyama K., Fujikawa S. & Park E.Y. 2001. Effect of consumed carbon to nitrogen ratio on mycelial morphology and arachidonic acid production in cultures of Mortierella alpina. J. Biosci. Bioeng. 91: 382-389.
15. Lindberg A.M. & Molin G. 1993. Effect of temperature and glucose supply on the production of polyunsaturated fatty acids by the fungus Mortierella alpina CCBS 343.66 in fermentor cultures. Appl. Microbiol. Biotechnol. 39: 450-455.
16. Perez-Guerra N., Torrado-Agrasar C., Lopez-Macias C. & Pastrana L. 2003. Main characteristics and applications of solid substrate fermentation. Electron. J. Environ. Agric. Food Chem. 2: 343-350.
17. nd Ed. Addison-Wesley Publishing Company, Inc., Philippines.
18. Shimuzu S., Kawashima H., Akimoto K., Shinmen Y. & Yamada H. 1989. Microbial conversion of an oil containing α-linolenic acid to an oil containing eicosapentaenoic acid. J. Am. Oil. Chem. Soc. 66: 342-347.
19. Sijtsma L., De Swaaf M.E. 2004. Biotechnological production and applications of the ω-3 polyunsaturated fatty acid docosahexaenoic acid. Appl. Microbiol. Biotechnol. 64: 146-153.
20. Slavikova L. & Certik M. 2005. Microbial preparation of polyunsaturated fatty acids by fungal solid state fermentation. Chem. Listy 99: 234-237.
21. Stredansky M., Conti E. & Salaris A. 2000. Production of polyunsaturated fatty acids by Pythium ultimum in solid state cultivation. Enzyme Microb. Technol. 26: 304-307.
22. Streekstra H. 1997. On the safety of Mortierella alpina for the production of food ingredients, such as arachidonic acid. J. Biotechnol. 56: 153-165.
23. Ward O.P. & Singh A. 2005. Omega-3/6 fatty acids: alternative sources of production. Process Biochem. 40: 3627-3652.
24. Zhu H. 2002. Utilization of rice bran by Pythium irregulare for lipid production. MSc Thesis, Louisiana State University.