Fungal production of eicosapentaenoic and arachidonic acids from industrial waste streams and crude soybean oil

Bioresource Technology

Volumn 67, Issue 2, 1999, Pages 101-110

  Cheng, Ming H ^a   Walker, Terry H ^a   Hulbert, Gregory J ^a   Raman, D Raj ^a  

^a UNIVERSITY OF TENNESSEE   (United States)

Author keywords

ARA; EPA; Fermentation; Fungi; Soya fiber; Soybean oil; Sucrose waste; Temperature

Indexed keywords

FATTY ACIDS; FERMENTATION; LIPIDS; OILS AND FATS; PH; TEMPERATURE;

ARACHIDONIC ACIDS; CRUDE SOYBEAN OIL; EICOSAPENTAENOIC ACIDS; FUNGAL PRODUCTION; INDUSTRIAL WASTE STREAMS;

FUNGI;

ARACHIDONIC ACID DERIVATIVE; GLUCOSE; ICOSAPENTAENOIC ACID; POLYSORBATE 80; POLYUNSATURATED FATTY ACID; SOYBEAN OIL; SUCROSE;

ARTICLE; FATTY ACID SYNTHESIS; FERMENTATION; FUNGUS CULTURE; INDUSTRIAL WASTE; PH; PRIORITY JOURNAL; TEMPERATURE;

EID: 0033080654     PISSN: 09608524     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-8524(98)00113-8     Document Type: Article

References (45)

1. Bajpai, P., Bajpai, P.K., 1993. Eicosapentaenoic acid (EPA) production from microorganisms: a review. J. Biotechnol. 30, 161-183.
2. Bajpai, P., Bajpai, P.K., Ward, O.P., 1991a. Effects of aging Mortierella mycelium on production of arachidonic and eicosapentaenoic acids. J. Am. Oil Chem. Soc., 68, 775-780.
3. Bajpai, P., Bajpai, P.K., Ward, O.P., 1991b. Eicosapentaenoic acid (EPA) formation: comparative studies with Mortierella strains and production by Mortierella elongata. Mycol. Res., 95, 1294-1298.
4. Bajpai, P., Bajpai, P.K., Ward, O.P., 1991c. Eicosapentaenoic acid (EPA) production by Mortierella alpina ATCC 32222. Appl. Biochem. Biotechnol., 31, 267-272.
5. Bajpai, P.K., Bajpai, P., Ward, O.P., 1991d. Arachidonic acid production by fungi. Appl. Environ. Microbiol., 57, 1255-1258.
6. Bajpai, P.K., Bajpai, P., Ward, O.P., 1991e. Optimization of production of docosahexaenoic acid (DHA) by Thraustochytrium aureum ATCC 34304. J. Am. Oil Chem. Soc., 68, 509-514.
7. Bajpai, P.K., Bajpai, P., Ward, O.P., 1991f. Production of arachidonic acid by Mortierella alpina ATCC 32222. J. Ind. Microbiol., 8, 179-186.
8. Bajpai, P.K., Bajpai, P., Ward, O.P., 1992. Optimization of culture conditions for production of EPA by Mortierella elongata NRRL 5513. J. Ind. Microbial. 9, 11-18.
9. Braden, L.M., Caroll, K.K., 1986. Dietary polyunsaturated fat in relation to mammary carcinogenesis in rats. Lipids 21, 285-288.
10. Christie, W.W., 1982. A simple procedure for rapid transmethylation of glycerolipids and cholesteryl esters. J. Lipid Res. 23, 1072-1075.
11. Dyerberg, J., 1986. Linoleate-derived polyunsaturated fatty acids and prevention of atherosclerosis. Nutr. Rev. 44, 125-134.
12. Friberg, S., 1976. Food emulsifiers. In: Food Emulsions. Marcel Dekker, New York, p. 70.
13. Hara, A., Radin, N.S., 1978. Lipid extraction of tissues with a low-toxicity solvent. Analyt. Biochem. 90, 420-426.
14. Hartmann, E., Beutelmann, P., Vanderkerhkove, O., Euler, R., Kohn, G., 1986. Moss cell cultures as sources of arachidonic and eicosapentaenoic acids. FEBS Lett. 198, 51-55.
15. Hulanicka, D., Erwin, J., Bloch, K.J., 1964. Lipid metabolism of Euglena gracillis. J. Biol. Chem. 239, 2778-2787.
16. Jareonkitmongkol, S., Sakuradani, E., Shimizu, S., 1993. A novel omega-5-desaturase-defective mutant of Mortierella alpina 1S-4 and its dihomo-gema-linolenic acid productivity. Appl. Environ. Microbiol. 59, 4300-4304.
17. Kendrick, A., Ratledge, C., 1992. Lipid formation in the oleaginous mold Entomophthora exitalis grown in continuous culture: effects of growth rate, temperature and dissolved oxygen tension on polyunsaturated fatty acids. Appl. Microbiol. Biotechnol. 37, 18-22.
18. Kremer, J.M., Bigauaoette, J., Michalek, A.V., Timchalk, M.A., Lininger, L., Rynes, R.I., Hucyck, C., Zieminski, J., Bartholomew, L. E., 1985. Effects of manipulation of dietary fatty acids on clinical manifestations of rheumatoid arthritis. Lancet i, 184-187.
19. Leaf, A., Weber, P., 1987. A new era for science in nutrition. Am. J. Clin. Nutr. 45 (Suppl.), 1048-1053.
20. Lepage, G., Roy, C.C., 1984. Improved recovery of fatty acid through direct transesterification without prior extraction or purification. J. Lipid Res. 25, 1391-1396.
21. Lo, G.S., 1990. Physiological effects and physico-chemical properties of soy cotyledon fiber. In: Furda, I., Brine, C.J. (Eds.), New Developments in Dietarty Fiber. Plenum Press, New York, pp. 49-66.
22. Neidleman, S., 1987. Effects of temperature on lipid unsaturation. Biotechnol. Gen. Eng. Rev. 5, 245-268.
23. O'Brien, D.J., Kurantz, M.J., Kwoczak, R., 1993. Production of eicosapentaenoic acid by the filamentous fungus Pythium irregulare. Appl. Microbiol. Biotechnol. 40, 211-214.
24. Radwan, S.S., 1991. Sources of C20-polyunsaturated fatty acids for biotechnological use. App. Microbiol. Biotechnol. 35, 421-430.
25. Ratledge, C., 1986. Lipids. In: Pape, H., Rehm, H.J. (Eds.), Biotechnology: a Comprehensive Treatise, Vol. 4. VCH Publishers, Deerfield Beach, FL, pp. 185-213.
26. Rounds, M. A., Nielsen, S. S., 1994. Basic principles of chromatography. In: Nielsen, S. S. (Ed.), Introduction to the Chemical Analysis of Foods. Jones and Bartlett, Boston, MA, pp. 403-424.
27. Salem Jr., N., Carlson, S.E., 1991. Growth and development in infants. In: Simopoulos, A.P., Kifer, R.R., Martin, R.E., Barlow, S.M. (Eds.), Health Effects of ω 3 Polyunsaturated Fatty Acids in Seafoods, Vol. 66. World Rev. Nutr. Diet. Karger., Basel, pp. 20-25.
28. SAS Institute Inc., 1990. SAS/STAT© User's Guide, 6th edn. Statistical Analysis System Institute, Gary, NC.
29. Shimizu, S., Yamada, H., 1990. Production of dietary and pharmacologically important polyunsaturated fatty acids (PUFA) by mirobiological processes. Comments. Agric. Food Chem. 2, 211-235.
30. Shimizu, S., Yamada, H., 1991. Biosynthesis of C-20 polyunsaturated fatty acids by Mortierella fungi. Microbial Utilization of Renewable Resources 7, 158-165.
31. Shimizu, S., Kawashima, H., Shinmen, Y., Akimoto, K., Yamada, H., 1988a. Production of eicosapentaenoic acid by Mortierella fungi. J. Am. Oil Chem. Soc., 65, 1455-1459.
32. Shimizu, S., Shinmen, Y., Kawashima, H., Akimoto, K., Yamada, H., 1988b. Fungal mycelia as a novel source of eicosapentaenoic acid. Biochim. Biophys. Acta., 150, 335-341.
33. Shimizu, S., Akimoto, K., Kawashima, H., Shinmen, Y., Yamada, H., 1989a. Production of dihomo-gema-linolenic acid (DGLA) by Mortierella alpina 1S-4. J. Am. Oil Chem. Soc., 66, 237-241.
34. Shimizu, S., Kawashima, H., Akimoto, K., Shinmen, Y., Yamada, H., 1989b. Conversion of linseed oil to an eicosapentaenoic acid-containing oil by Mortierella alpina 1S-4 at low temperature. Appl. Microbiol. Biotechnol., 32, 1-4.
35. Shimizu, S., Kawashima, H., Akimoto, K., Shinmen, Y., Yamada, H., 1989c. Microbial conversion of an oil containing alpha-linolenic acid to an oil containing eicosapentaenoic acid. J. Am. Oil Chem. Soc., 66, 342-347.
36. Shimizu, S., Kawashima, H., Akimoto, K., Shinmen, Y., Yamada, H., 1991. Production of odd chain polyunsaturated fatty acids by Mortierella fungi. J. Am. Oil Chem. Soc. 68, 254-258.
37. Shimizu, S., Kawashima, H., Wada, M., Yamada, H., 1992. Occurrence of a novel sterol, 24,25-methylenecholest-5-en-3beta-ol, in Mortierella alpina 1S-4. Lipids 27, 481-483.
38. Shirasaka, N., Shimizu, S., 1995. Production of eicosapentaenoic acid by Saprolegnia sp. 28YTF-1. J. Am. Oil Chem. Soc. 72, 1545-1549.
39. Simopoulos, A.P., 1989. Summary of the NATO advanced research workshop on dietary ω-3 and ω-6 fatty acids: biological effects and nutritional essentiality. J. Nutr. 119, 521-528.
40. Simopoulos, A.P., Kifer, R.R., Martin, R.E., Barlow, S.M., 1991. In: Health Effects of Omega-3 Polyunsaturated Fatty Acids in Seafoods: Proceedings of the 2nd International Conference, Vol. 66. World Review of Nutrition and Dietetics, Basel, New York.
41. Stauffer, C. E., 1996. Composition of fats and oils. In: Fats and Oils. Eagan Press, St. Paul, Minnesota, p. 131.
42. Stinson, E.E., Kwoczak, R., Kurantz, M.J., 1991. Effect of cultural conditions on production of eicosapentaenoic acid by Pythium irregulare. J. Ind. Microbiol. 8, 171-178.
43. 20 polyunsaturated fatty acid production in Pythium ultimum. In: Kyle, D. J., Ratledge, C. (Eds.), Industrial Applications of Single Cell Oils. American Oil Chemists' Society, Champaign, pp. 98-117.
44. Yazawa, K., Araki, K., Okazaki, N., Watanabe, K., Ishikawa, C., Inoue, A., Numao, N., Kondo, K., 1988. Production of eicosapentaenoic acid by marine bacteria. J. Biochem. 103, 5-7.
45. Yongmanitchai, W., Ward, O.P., 1989. Omega-3 fatty acids: alternative sources of production. Proc. Biochem. 24, 117-125.