Structural features of cephalosporin acylase reveal the basis of autocatalytic activation

Biochemical and Biophysical Research Communications

Volumn 390, Issue 2, 2009, Pages 342-348

  Cho, Ki Joon ^a   Kim, Jin Kwang ^a   Lee, Ji Hye ^a   Shin, Hye Jeong ^a   Park, Sung Soo ^a   Kim, Kyung Hyun ^a  

^a Korea University   (South Korea)

Author keywords

Autoproteolysis; Cephalosporin acylase; Intermediate structure; Precursor activation; Slow processing mutant

Indexed keywords

CEPHALOSPORIN ACYLASE; GLUTAMIC ACID; HYDROLASE; NUCLEOPHILE; SERINE; UNCLASSIFIED DRUG; WATER;

ARTICLE; CATALYSIS; CONFORMATIONAL TRANSITION; ENZYME ACTIVATION; ENZYME CONFORMATION; ENZYME DEGRADATION; ENZYME KINETICS; ENZYME STABILITY; ENZYME STRUCTURE; MUTATION; NONHUMAN; PRIORITY JOURNAL;

CATALYSIS; CRYSTALLOGRAPHY, X-RAY; ENZYME ACTIVATION; MUTATION; PENICILLIN AMIDASE; PROTEIN CONFORMATION; PSEUDOMONAS;

EID: 70350128754     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.09.134     Document Type: Article

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