Insight into autoproteolytic activation from the structure of cephalosporin acylase: A protein with two proteolytic chemistries

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 6, 2006, Pages 1732-1737

  Kim, Jin Kwang ^a   Yang, In Seok ^a   Shin, Hye Jeong ^a   Cho, Ki Joon ^a   Ryu, Eui Kyung ^a,b   Kim, Sun Hwa ^a,c   Park, Sung Soo ^a   Kim, Kyung Hyun ^a  

^a Korea University   (South Korea)

^b Pohang University of Science and Technology (POSTECH)   (South Korea)

^c The Catholic University of Korea   (South Korea)

Author keywords

Autoproteolysis; Intermediate structure; Precursor activation; Pro segment

Indexed keywords

CEPHALOSPORIN ACYLASE; GLUTAMIC ACID; HYDROLASE; NUCLEOPHILE HYDROLASE; PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; CRYSTAL STRUCTURE; ENZYME ACTIVATION; ENZYME CONFORMATION; ENZYME DEGRADATION; ENZYME STRUCTURE; PRIORITY JOURNAL; PROTEIN FAMILY;

AMINO ACID SEQUENCE; CATIONS; ENZYME ACTIVATION; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PENICILLIN AMIDASE; PROTEIN STRUCTURE, TERTIARY; PSEUDOMONAS; STRUCTURAL HOMOLOGY, PROTEIN;

EID: 32444443303     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0507862103     Document Type: Article

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