Induction of hepatic cyclooxygenase-2 by hyperhomocysteinemia via nuclear factor-κB activation

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 297, Issue 4, 2009, Pages

  Wu, Nan ^a,b   Siow, Yaw L ^a,b,c   Karmin, O ^a,b  

^a ST BONIFACE GENERAL HOSPITAL   (Canada)

^b UNIVERSITY OF MANITOBA   (Canada)

^c AGRICULTURE AND AGRI FOOD CANADA   (Canada)

Author keywords

Homocysteine; Inflammatory response; Liver injury; Oxidative stress

Indexed keywords

4 HYDROXY TETRAMETHYL PIPERIDINE 1 OXYL; HOMOCYSTEINE; I KAPPA B; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; METHIONINE; PIPERIDONE DERIVATIVE; PROSTAGLANDIN SYNTHASE; SUPEROXIDE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GEL MOBILITY SHIFT ASSAY; HYPERHOMOCYSTEINEMIA; LIVER FUNCTION; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SPRAGUE DAWLEY RAT;

ANIMALS; ANTIOXIDANTS; CELL NUCLEUS; CYCLIC N-OXIDES; CYCLOOXYGENASE 2; DISEASE MODELS, ANIMAL; ENZYME INDUCTION; HEPATITIS; HOMOCYSTEINE; HYPERHOMOCYSTEINEMIA; I-KAPPA B PROTEINS; LIVER; MALE; NF-KAPPA B; OXIDATIVE STRESS; PHOSPHORYLATION; PYRROLIDINES; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SPIN LABELS; SUPEROXIDES; THIOCARBAMATES; TIME FACTORS;

EID: 70350113875     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00293.2009     Document Type: Article

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