-
1
-
-
0029924110
-
Prostaglandin endoperoxide synthase: Why two isoforms?
-
Williams CS, DuBois RN. Prostaglandin endoperoxide synthase: why two isoforms? Am J Physiol 1996;270:G393-400.
-
(1996)
Am J Physiol
, vol.270
-
-
Williams, C.S.1
DuBois, R.N.2
-
2
-
-
0030470356
-
Regulation of COX-2 gene expression in rat uterus in vivo and in vitro
-
Arslan A, Zingg HH. Regulation of COX-2 gene expression in rat uterus in vivo and in vitro. Prostaglandins 1996;52:463-81.
-
(1996)
Prostaglandins
, vol.52
, pp. 463-481
-
-
Arslan, A.1
Zingg, H.H.2
-
3
-
-
0030920861
-
Delayed release of prostaglandins from arachidonic acid and kinetic changes in prostaglandin H synthase activity on the induction of prostaglandin H synthase-2 after lipopolysaccharide-treatment of RAW264.7 macrophage-like cells
-
Tanaka Y, Takahashi M, Kawaguchi M, et al. Delayed release of prostaglandins from arachidonic acid and kinetic changes in prostaglandin H synthase activity on the induction of prostaglandin H synthase-2 after lipopolysaccharide-treatment of RAW264.7 macrophage-like cells. Biol Pharm Bull 1997;20:322-6.
-
(1997)
Biol Pharm Bull
, vol.20
, pp. 322-326
-
-
Tanaka, Y.1
Takahashi, M.2
Kawaguchi, M.3
-
4
-
-
0027944075
-
Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain
-
Seibert K, Zhang Y, Leahy K, et al. Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain. Proc Natl Acad Sci USA 1994;91:12013-17.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 12013-12017
-
-
Seibert, K.1
Zhang, Y.2
Leahy, K.3
-
5
-
-
0344759120
-
Role of leukocyte influx in tissue prostaglandin H synthase-2 overexpression induced by phorbol ester and arachidonic acid in skin
-
Sanchez T, Moreno JJ. Role of leukocyte influx in tissue prostaglandin H synthase-2 overexpression induced by phorbol ester and arachidonic acid in skin. Biochem Pharmacol 1999;58:877-9.
-
(1999)
Biochem Pharmacol
, vol.58
, pp. 877-879
-
-
Sanchez, T.1
Moreno, J.J.2
-
6
-
-
0036169713
-
Expression of cyclooxygenase-2 in chronic hepatitis B and the effects of anti-viral therapy
-
Cheng AS, Chan HL, Leung NW, et al. Expression of cyclooxygenase-2 in chronic hepatitis B and the effects of anti-viral therapy. Aliment Pharmacol Ther 2002;16:251-60.
-
(2002)
Aliment Pharmacol Ther
, vol.16
, pp. 251-260
-
-
Cheng, A.S.1
Chan, H.L.2
Leung, N.W.3
-
7
-
-
4744351642
-
Expression of HBx and COX-2 in chronic hepatitis B, cirrhosis and hepatocellular carcinoma: Implication of HBx in upregulation of COX-2
-
Cheng AS, Chan HL, Leung WK, et al. Expression of HBx and COX-2 in chronic hepatitis B, cirrhosis and hepatocellular carcinoma: implication of HBx in upregulation of COX-2. Mod Pathol 2004;17:1169-79.
-
(2004)
Mod Pathol
, vol.17
, pp. 1169-1179
-
-
Cheng, A.S.1
Chan, H.L.2
Leung, W.K.3
-
8
-
-
33644792520
-
Troglitazone inhibits tumor growth in hepatocellular carcinoma in vitro and in vivo
-
Yu J, Qiao L, Zimmermann L, et al. Troglitazone inhibits tumor growth in hepatocellular carcinoma in vitro and in vivo. Hepatology 2006;43:134-43.
-
(2006)
Hepatology
, vol.43
, pp. 134-143
-
-
Yu, J.1
Qiao, L.2
Zimmermann, L.3
-
9
-
-
33645963118
-
COX-2 induction in mice with experimental nutritional steatohepatitis: Role as pro-inflammatory mediator
-
Yu J, Ip E, Dela Pena A, et al. COX-2 induction in mice with experimental nutritional steatohepatitis: role as pro-inflammatory mediator. Hepatology 2006;43:826-36.
-
(2006)
Hepatology
, vol.43
, pp. 826-836
-
-
Yu, J.1
Ip, E.2
Dela Pena, A.3
-
10
-
-
0025008962
-
Distinct positive and negative elements control the limited hepatocyte and choroid plexus expression of transthyretin in transgenic mice
-
Yan C, Costa RH, Darnell JE Jr, et al. Distinct positive and negative elements control the limited hepatocyte and choroid plexus expression of transthyretin in transgenic mice. EMBO J 1990;9:869-78.
-
(1990)
EMBO J
, vol.9
, pp. 869-878
-
-
Yan, C.1
Costa, R.H.2
Darnell Jr, J.E.3
-
11
-
-
33644896206
-
Effects of a novel tylophorine analog on collagen-induced arthritis through inhibition of the innate immune response
-
You X, Pan M, Gao W, et al. Effects of a novel tylophorine analog on collagen-induced arthritis through inhibition of the innate immune response. Arthritis Rheum 2006;54:877-86.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 877-886
-
-
You, X.1
Pan, M.2
Gao, W.3
-
12
-
-
33645968418
-
Effect of celecoxib on experimental liver fibrosis in rat
-
Hui AY, Leung WK, Chan HL, et al. Effect of celecoxib on experimental liver fibrosis in rat. Liver Int 2006;26:125-36.
-
(2006)
Liver Int
, vol.26
, pp. 125-136
-
-
Hui, A.Y.1
Leung, W.K.2
Chan, H.L.3
-
13
-
-
5444253143
-
PGE2 exerts its effect on the LPS-induced release of TNF-alpha, ET-1, IL-1alpha, IL-6 and IL-10 via the EP2 and EP4 receptor in rat liver macrophages
-
Treffkorn L, Scheibe R, Maruyama T, et al. PGE2 exerts its effect on the LPS-induced release of TNF-alpha, ET-1, IL-1alpha, IL-6 and IL-10 via the EP2 and EP4 receptor in rat liver macrophages. Prostagland Other Lipid Mediat 2004;74:113-23.
-
(2004)
Prostagland Other Lipid Mediat
, vol.74
, pp. 113-123
-
-
Treffkorn, L.1
Scheibe, R.2
Maruyama, T.3
-
14
-
-
2342587509
-
Hyperplastic gastric tumors induced by activated macrophages in COX-2/mPGES-1 transgenic mice
-
Oshima H, Oshima M, Inaba K, et al. Hyperplastic gastric tumors induced by activated macrophages in COX-2/mPGES-1 transgenic mice. EMBO J 2004;23:1669-78.
-
(2004)
EMBO J
, vol.23
, pp. 1669-1678
-
-
Oshima, H.1
Oshima, M.2
Inaba, K.3
-
16
-
-
0029956219
-
Elevated interleukin 6 is induced by prostaglandin E2 in a murine model of inflammation: Possible role of cyclooxygenase-2
-
Hinson RM, Williams JA, Shacter E. Elevated interleukin 6 is induced by prostaglandin E2 in a murine model of inflammation: possible role of cyclooxygenase-2. Proc Natl Acad Sci USA 1996;93:4885-90.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 4885-4890
-
-
Hinson, R.M.1
Williams, J.A.2
Shacter, E.3
-
17
-
-
0031179646
-
IL-12-deficient dendritic cells, generated in the presence of prostaglandin E2, promote type 2 cytokine production in maturing human naive T helper cells
-
Kalinski P, Hilkens CM, Snijders A, et al. IL-12-deficient dendritic cells, generated in the presence of prostaglandin E2, promote type 2 cytokine production in maturing human naive T helper cells. J Immunol 1997;159:28-35.
-
(1997)
J Immunol
, vol.159
, pp. 28-35
-
-
Kalinski, P.1
Hilkens, C.M.2
Snijders, A.3
-
18
-
-
0030898841
-
Prostaglandins induce proliferation of rat hepatocytes through a prostaglandin E2 receptor EP3 subtype
-
Hashimoto N, Watanabe T, Ikeda Y, et al. Prostaglandins induce proliferation of rat hepatocytes through a prostaglandin E2 receptor EP3 subtype. Am J Physiol 1997;272:G597-604.
-
(1997)
Am J Physiol
, vol.272
-
-
Hashimoto, N.1
Watanabe, T.2
Ikeda, Y.3
-
19
-
-
0033403626
-
Cyclooxygenase- deficient mice. A summary of their characteristics and susceptibilities to inflammation and carcinogenesis
-
Langenboch R, Loftin CD, Lee C, et al. Cyclooxygenase- deficient mice. A summary of their characteristics and susceptibilities to inflammation and carcinogenesis. Ann NY Acad Sci 1999;889:52-61.
-
(1999)
Ann NY Acad Sci
, vol.889
, pp. 52-61
-
-
Langenboch, R.1
Loftin, C.D.2
Lee, C.3
-
20
-
-
27744458510
-
NF-kappaB activation, rather than TNF, mediates hepatic inflammation in a murine dietary model of steatohepatitis
-
Dela Pena A, Leclercq I, Field J, et al. NF-kappaB activation, rather than TNF, mediates hepatic inflammation in a murine dietary model of steatohepatitis. Gastroenterology 2005;129:1663-74.
-
(2005)
Gastroenterology
, vol.129
, pp. 1663-1674
-
-
Dela Pena, A.1
Leclercq, I.2
Field, J.3
-
21
-
-
0346505340
-
The IKK NF-kappa B system: A treasure trove for drug development
-
Karin M, Yamamoto Y, Wang QM. The IKK NF-kappa B system: a treasure trove for drug development. Nat Rev Drug Discov 2004;3:17-26.
-
(2004)
Nat Rev Drug Discov
, vol.3
, pp. 17-26
-
-
Karin, M.1
Yamamoto, Y.2
Wang, Q.M.3
-
22
-
-
0028147767
-
Structure of the human cyclooxygenase-2 gene
-
Appleby SB, Ristimaki A, Neilson K, et al. Structure of the human cyclooxygenase-2 gene. Biochem J 1994;302:723-7.
-
(1994)
Biochem J
, vol.302
, pp. 723-727
-
-
Appleby, S.B.1
Ristimaki, A.2
Neilson, K.3
-
23
-
-
0031559584
-
Evidence for involvement of NF-kappaB in the transcriptional control of COX-2 gene expression by IL-1beta
-
Newton R, Kuitert LM, Bergmann M, et al. Evidence for involvement of NF-kappaB in the transcriptional control of COX-2 gene expression by IL-1beta. Biochem Biophys Res Commun 1997;237:28-32.
-
(1997)
Biochem Biophys Res Commun
, vol.237
, pp. 28-32
-
-
Newton, R.1
Kuitert, L.M.2
Bergmann, M.3
-
24
-
-
4644324186
-
NF-kappaB functions as a tumour promoter in inflammation-associated cancer
-
Pikarsky E, Porat RM, Stein I, et al. NF-kappaB functions as a tumour promoter in inflammation-associated cancer. Nature 2004;431:461-6.
-
(2004)
Nature
, vol.431
, pp. 461-466
-
-
Pikarsky, E.1
Porat, R.M.2
Stein, I.3
-
27
-
-
0029048073
-
Tumor necrosis factor-induced hepatic DNA fragmentation as an early marker of T cell-dependent liver injury in mice
-
Gantner F, Leist M, Jilg S, et al. Tumor necrosis factor-induced hepatic DNA fragmentation as an early marker of T cell-dependent liver injury in mice. Gastroenterology 1995;109:166-76.
-
(1995)
Gastroenterology
, vol.109
, pp. 166-176
-
-
Gantner, F.1
Leist, M.2
Jilg, S.3
-
28
-
-
0028795171
-
Concanavalin A-induced T-cell-mediated hepatic injury in mice: The role of tumor necrosis factor
-
Gantner F, Leist M, Lohse AW, et al. Concanavalin A-induced T-cell-mediated hepatic injury in mice: the role of tumor necrosis factor. Hepatology 1995;21:190-8.
-
(1995)
Hepatology
, vol.21
, pp. 190-198
-
-
Gantner, F.1
Leist, M.2
Lohse, A.W.3
-
29
-
-
0028999453
-
Tumor necrosis factor-induced hepatocyte apoptosis precedes liver failure in experimental murine shock models
-
Leist M, Gantner F, Bohlinger I, et al. Tumor necrosis factor-induced hepatocyte apoptosis precedes liver failure in experimental murine shock models. Am J Pathol 1995;146:1220-34.
-
(1995)
Am J Pathol
, vol.146
, pp. 1220-1234
-
-
Leist, M.1
Gantner, F.2
Bohlinger, I.3
-
30
-
-
0026341918
-
Neutrophil-induced liver cell injury in endotoxin shock is a CD11b/CD18-dependent mechanism
-
Jaeschke H, Farhood A, Smith CW. Neutrophil-induced liver cell injury in endotoxin shock is a CD11b/CD18-dependent mechanism. Am J Physiol 1991;261:G1051-6.
-
(1991)
Am J Physiol
, vol.261
-
-
Jaeschke, H.1
Farhood, A.2
Smith, C.W.3
-
31
-
-
0023953471
-
Biology of interleukin 1
-
Dinarello CA. Biology of interleukin 1. FASEB J 1988;2:108-15.
-
(1988)
FASEB J
, vol.2
, pp. 108-115
-
-
Dinarello, C.A.1
-
32
-
-
0028345668
-
In vivo cytokine gene expression in various T cell subsets of the autoimmune MRL/Mp-Ipr/Ipr mouse
-
Mori K, Kobayashi S, Inobe M, et al. In vivo cytokine gene expression in various T cell subsets of the autoimmune MRL/Mp-Ipr/Ipr mouse. Autoimmunity 1994;17:49-57.
-
(1994)
Autoimmunity
, vol.17
, pp. 49-57
-
-
Mori, K.1
Kobayashi, S.2
Inobe, M.3
-
33
-
-
0023639560
-
Regulation of tumor necrosis factor (TNF) expression: Interferon-gamma enhances the accumulation of mRNA for TNF induced by lipopolysaccharide in murine peritoneal macrophages
-
Koerner TJ, Adams DO, Hamilton TA. Regulation of tumor necrosis factor (TNF) expression: interferon-gamma enhances the accumulation of mRNA for TNF induced by lipopolysaccharide in murine peritoneal macrophages. Cell Immunol 1987;109:437-43.
-
(1987)
Cell Immunol
, vol.109
, pp. 437-443
-
-
Koerner, T.J.1
Adams, D.O.2
Hamilton, T.A.3
-
34
-
-
0022982147
-
Gamma interferon enhances macrophage transcription of the tumor necrosis factor/cachectin, interleukin 1, and urokinase genes, which are controlled by short-lived repressors
-
Collart MA, Belin D, Vassalli JD, et al. Gamma interferon enhances macrophage transcription of the tumor necrosis factor/cachectin, interleukin 1, and urokinase genes, which are controlled by short-lived repressors. J Exp Med 1986;164:2113-18.
-
(1986)
J Exp Med
, vol.164
, pp. 2113-2118
-
-
Collart, M.A.1
Belin, D.2
Vassalli, J.D.3
-
35
-
-
0028109394
-
Evidence for the involvement of interleukin 10 in the differential deactivation of murine peritoneal macrophages by prostaglandin E2
-
Strassmann G, Patil-Koota V, Finkelman F, et al. Evidence for the involvement of interleukin 10 in the differential deactivation of murine peritoneal macrophages by prostaglandin E2. J Exp Med 1994;180:2365-70.
-
(1994)
J Exp Med
, vol.180
, pp. 2365-2370
-
-
Strassmann, G.1
Patil-Koota, V.2
Finkelman, F.3
-
36
-
-
0030781140
-
In vivo suppression of NF-kappa B and preservation of I kappa B alpha by interleukin-10 and interleukin-13
-
Lentsch AB, Shanley TP, SarmaV, et al. In vivo suppression of NF-kappa B and preservation of I kappa B alpha by interleukin-10 and interleukin-13. J Clin Invest 1997;100:2443-8.
-
(1997)
J Clin Invest
, vol.100
, pp. 2443-2448
-
-
Lentsch, A.B.1
Shanley, T.P.2
SarmaV3
-
37
-
-
0025960837
-
Fibrogenic cytokines: The role of immune mediators in the development of scar tissue
-
Kovacs EJ. Fibrogenic cytokines: the role of immune mediators in the development of scar tissue. Immunol Today 1991;12:17-23.
-
(1991)
Immunol Today
, vol.12
, pp. 17-23
-
-
Kovacs, E.J.1
-
38
-
-
0035287313
-
Nitric oxide induces MIP-2 transcription in rat renal mesangial cells and in a rat model of glomerulonephritis
-
Walpen S, Beck KF, Schaefer L, et al. Nitric oxide induces MIP-2 transcription in rat renal mesangial cells and in a rat model of glomerulonephritis. FASEB J 2001;15:571-3.
-
(2001)
FASEB J
, vol.15
, pp. 571-573
-
-
Walpen, S.1
Beck, K.F.2
Schaefer, L.3
-
39
-
-
0036227449
-
Differential activation of innate immune responses by adenovirus and adeno-associated virus vectors
-
Zaiss AK, Liu Q, Bowen GP, et al. Differential activation of innate immune responses by adenovirus and adeno-associated virus vectors. J Virol 2002;76:4580-90.
-
(2002)
J Virol
, vol.76
, pp. 4580-4590
-
-
Zaiss, A.K.1
Liu, Q.2
Bowen, G.P.3
-
40
-
-
0034086273
-
Bile duct ligation in rats induces biliary expression of cytokine-induced neutrophil chemoattractant
-
Saito JM, Maher JJ. Bile duct ligation in rats induces biliary expression of cytokine-induced neutrophil chemoattractant. Gastroenterology 2000;118:1157-68.
-
(2000)
Gastroenterology
, vol.118
, pp. 1157-1168
-
-
Saito, J.M.1
Maher, J.J.2
-
41
-
-
15844425587
-
Critical involvement of interferon gamma in the pathogenesis of T-cell activation-associated hepatitis and regulatory mechanisms of interleukin-6 for the manifestations of hepatitis
-
Mizuhara H, Uno M, Seki N, et al. Critical involvement of interferon gamma in the pathogenesis of T-cell activation-associated hepatitis and regulatory mechanisms of interleukin-6 for the manifestations of hepatitis. Hepatology 1996;23:1608-15.
-
(1996)
Hepatology
, vol.23
, pp. 1608-1615
-
-
Mizuhara, H.1
Uno, M.2
Seki, N.3
-
42
-
-
0033855570
-
Tumor necrosis factor alpha in the pathogenesis of human and murine fulminant hepatic failure
-
Streetz K, Leifeld L, Grundmann D, et al. Tumor necrosis factor alpha in the pathogenesis of human and murine fulminant hepatic failure. Gastroenterology 2000;119:446-60.
-
(2000)
Gastroenterology
, vol.119
, pp. 446-460
-
-
Streetz, K.1
Leifeld, L.2
Grundmann, D.3
-
43
-
-
0031739422
-
Involvement of Fas/Fas ligand system-mediated apoptosis in the development of concanavalin A-induced hepatitis
-
Tagawa Y, Kakuta S, Iwakura Y. Involvement of Fas/Fas ligand system-mediated apoptosis in the development of concanavalin A-induced hepatitis. Eur J Immunol 1998;28:4105-13.
-
(1998)
Eur J Immunol
, vol.28
, pp. 4105-4113
-
-
Tagawa, Y.1
Kakuta, S.2
Iwakura, Y.3
-
44
-
-
2442486078
-
COX-2 inhibition demonstrates potent anti-proliferative effects on bladder cancer in vitro
-
Mohseni H, Zaslau S, McFadden D, et al. COX-2 inhibition demonstrates potent anti-proliferative effects on bladder cancer in vitro. J Surg Res 2004;119:138-42.
-
(2004)
J Surg Res
, vol.119
, pp. 138-142
-
-
Mohseni, H.1
Zaslau, S.2
McFadden, D.3
-
45
-
-
0022597999
-
Modulation of keratinocyte proliferation in vitro by endogenous prostaglandin synthesis
-
Pentland AP, Needleman P. Modulation of keratinocyte proliferation in vitro by endogenous prostaglandin synthesis. J Clin Invest 1986;77:246-51.
-
(1986)
J Clin Invest
, vol.77
, pp. 246-251
-
-
Pentland, A.P.1
Needleman, P.2
-
46
-
-
0027276885
-
Epithelial cell proliferation and islet neogenesis in IFN-γ transgenic mice
-
Gu D, Sarvetnick N. Epithelial cell proliferation and islet neogenesis in IFN-γ transgenic mice. Development 1993;118:33-46.
-
(1993)
Development
, vol.118
, pp. 33-46
-
-
Gu, D.1
Sarvetnick, N.2
-
47
-
-
0034051506
-
The role of prostaglandin synthesis in prostate cancer
-
Badawi AF. The role of prostaglandin synthesis in prostate cancer. BJU Int 2000;85:451-62.
-
(2000)
BJU Int
, vol.85
, pp. 451-462
-
-
Badawi, A.F.1
-
48
-
-
0035966059
-
Anti-Fas induces hepatic chemokines and promotes inflammation by an NF-kappa B-independent, caspase-3-dependent pathway
-
Faouzi S, Burckhardt BE, Hanson JC, et al. Anti-Fas induces hepatic chemokines and promotes inflammation by an NF-kappa B-independent, caspase-3-dependent pathway. J Biol Chem 2001;276:49077-82.
-
(2001)
J Biol Chem
, vol.276
, pp. 49077-49082
-
-
Faouzi, S.1
Burckhardt, B.E.2
Hanson, J.C.3
-
49
-
-
0029102898
-
Interleukin 12 suppresses autoantibody production by reversing helper T-cell phenotype in hepatitis Be antigen transgenic mice
-
Milich DR, Wolf SF, Hughes JL, et al. Interleukin 12 suppresses autoantibody production by reversing helper T-cell phenotype in hepatitis Be antigen transgenic mice. Proc Natl Acad Sci USA 1995;92:6847-51.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 6847-6851
-
-
Milich, D.R.1
Wolf, S.F.2
Hughes, J.L.3
-
50
-
-
33644661410
-
Pathogenic role of B cells in anti-CD40-induced necroinflammatory liver disease
-
Kimura K, Moriwaki H, Nagaki M, et al. Pathogenic role of B cells in anti-CD40-induced necroinflammatory liver disease. Am J Pathol 2006;168:786-95.
-
(2006)
Am J Pathol
, vol.168
, pp. 786-795
-
-
Kimura, K.1
Moriwaki, H.2
Nagaki, M.3
|