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Volumn 40, Issue 6, 2009, Pages 493-498

The Therapeutic Vaccine: Is it Feasible?

Author keywords

Cervical cancer; HPV infections; HPV vaccines; Immune mechanism controlling HPV infections; Therapeutic vaccine

Indexed keywords

ADJUVANT; CALRETICULIN; HPV16 E7 35MER PEPTIDE; HPV16 L2 E6 E7 FUSION PROTEIN; HSP 65 E7 VACCINE; HYBRID PROTEIN; LIPOPROTEIN; LIPOPROTEIN D VACCINE; PEPTIDE VACCINE; PLACEBO; PROTEIN E7; UNCLASSIFIED DRUG; VACCINIA VECTOR; VIRUS VACCINE; VIRUS VECTOR; WART VIRUS VACCINE;

EID: 70350077522     PISSN: 01884409     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.arcmed.2009.07.003     Document Type: Review
Times cited : (15)

References (73)
  • 1
    • 0023506129 scopus 로고
    • Interferon treatment of human genital papillomavirus infection: importance of viral type
    • Schneider A., Papendick U., Gissmann L., et al. Interferon treatment of human genital papillomavirus infection: importance of viral type. Int J Cancer 40 (1987) 610-614
    • (1987) Int J Cancer , vol.40 , pp. 610-614
    • Schneider, A.1    Papendick, U.2    Gissmann, L.3
  • 2
    • 33847379522 scopus 로고    scopus 로고
    • TLR9 expression and function is abolished by the cervical cancer-associated human papillomavirus type 16
    • Hasan U.A., Bates E., Takeshita F., et al. TLR9 expression and function is abolished by the cervical cancer-associated human papillomavirus type 16. J Immunol 178 (2007) 3186-3197
    • (2007) J Immunol , vol.178 , pp. 3186-3197
    • Hasan, U.A.1    Bates, E.2    Takeshita, F.3
  • 3
    • 0034954453 scopus 로고    scopus 로고
    • Control of interferon signaling in human papillomavirus infection
    • Koromilas A.E., Li S., and Matlashewski G. Control of interferon signaling in human papillomavirus infection. Cytokine Growth Factor Rev 12 (2001) 157-170
    • (2001) Cytokine Growth Factor Rev , vol.12 , pp. 157-170
    • Koromilas, A.E.1    Li, S.2    Matlashewski, G.3
  • 4
    • 0037105486 scopus 로고    scopus 로고
    • Human papillomavirus virus-like particles do not activate Langerhans cells: a possible immune escape mechanism used by human papillomaviruses
    • Fausch S.C., Da Silva D.M., Rudolf M.P., et al. Human papillomavirus virus-like particles do not activate Langerhans cells: a possible immune escape mechanism used by human papillomaviruses. J Immunol 169 (2002) 3242-3249
    • (2002) J Immunol , vol.169 , pp. 3242-3249
    • Fausch, S.C.1    Da Silva, D.M.2    Rudolf, M.P.3
  • 5
    • 0038107894 scopus 로고    scopus 로고
    • Depletion of Langerhans cells in human papillomavirus type 16-infected skin is associated with E6-mediated down regulation of E-cadherin
    • Matthews K., Leong C.M., Baxter L., et al. Depletion of Langerhans cells in human papillomavirus type 16-infected skin is associated with E6-mediated down regulation of E-cadherin. J Virol 77 (2003) 8378-8385
    • (2003) J Virol , vol.77 , pp. 8378-8385
    • Matthews, K.1    Leong, C.M.2    Baxter, L.3
  • 6
    • 37549063455 scopus 로고    scopus 로고
    • The E5 protein of the human papillomavirus type 16 down-regulates HLA-I surface expression in calnexin-expressing but not in calnexin-deficient cells
    • Gruener M., Bravo I.G., Momburg F., et al. The E5 protein of the human papillomavirus type 16 down-regulates HLA-I surface expression in calnexin-expressing but not in calnexin-deficient cells. Virol J 4 (2007) 116
    • (2007) Virol J , vol.4 , pp. 116
    • Gruener, M.1    Bravo, I.G.2    Momburg, F.3
  • 7
    • 20244384561 scopus 로고    scopus 로고
    • Natural history and possible reactivation of human papillomavirus in human immunodeficiency virus-positive women
    • Strickler H.D., Burk R.D., Fazzari M., et al. Natural history and possible reactivation of human papillomavirus in human immunodeficiency virus-positive women. J Natl Cancer Inst 97 (2005) 577-586
    • (2005) J Natl Cancer Inst , vol.97 , pp. 577-586
    • Strickler, H.D.1    Burk, R.D.2    Fazzari, M.3
  • 8
    • 0034960889 scopus 로고    scopus 로고
    • Immunity to oncogenic human papillomaviruses
    • Konya J., and Dillner J. Immunity to oncogenic human papillomaviruses. Adv Cancer Res 82 (2001) 205-238
    • (2001) Adv Cancer Res , vol.82 , pp. 205-238
    • Konya, J.1    Dillner, J.2
  • 9
    • 0035105442 scopus 로고    scopus 로고
    • Cell-mediated immune response to human papillomavirus infection
    • Scott M., Nakagawa M., and Moscicki A.B. Cell-mediated immune response to human papillomavirus infection. Clin Diagn Lab Immunol 8 (2001) 209-220
    • (2001) Clin Diagn Lab Immunol , vol.8 , pp. 209-220
    • Scott, M.1    Nakagawa, M.2    Moscicki, A.B.3
  • 10
    • 0033747238 scopus 로고    scopus 로고
    • Natural HPV immunity and vaccination strategies
    • Stern P.L., Brown M., Stacey S.N., et al. Natural HPV immunity and vaccination strategies. J Clin Virol 19 (2000) 57-66
    • (2000) J Clin Virol , vol.19 , pp. 57-66
    • Stern, P.L.1    Brown, M.2    Stacey, S.N.3
  • 11
    • 0022499152 scopus 로고
    • Immunohistologic analysis of the phenomenon of spontaneous regression of numerous flat warts
    • Aiba S., Rokugo M., and Tagami H. Immunohistologic analysis of the phenomenon of spontaneous regression of numerous flat warts. Cancer 58 (1986) 1246-1251
    • (1986) Cancer , vol.58 , pp. 1246-1251
    • Aiba, S.1    Rokugo, M.2    Tagami, H.3
  • 12
    • 0028559782 scopus 로고
    • Immunological events in regressing genital warts
    • Coleman N., Birley H.D., Renton A.M., et al. Immunological events in regressing genital warts. Am J Clin Pathol 102 (1994) 768-774
    • (1994) Am J Clin Pathol , vol.102 , pp. 768-774
    • Coleman, N.1    Birley, H.D.2    Renton, A.M.3
  • 13
    • 0035062542 scopus 로고    scopus 로고
    • Correlation between mRNA levels of IL-6 and TNF alpha and progression rate in anal squamous epithelial lesions from HIV-positive men
    • Arany I., Muldrow M., and Tyring S.K. Correlation between mRNA levels of IL-6 and TNF alpha and progression rate in anal squamous epithelial lesions from HIV-positive men. Anticancer Res 21 (2001) 425-428
    • (2001) Anticancer Res , vol.21 , pp. 425-428
    • Arany, I.1    Muldrow, M.2    Tyring, S.K.3
  • 14
    • 0032802988 scopus 로고    scopus 로고
    • Enhancement of the innate and cellular immune response in patients with genital warts treated with topical imiquimod cream 5%
    • Arany I., Tyring S.K., Stanley M.A., et al. Enhancement of the innate and cellular immune response in patients with genital warts treated with topical imiquimod cream 5%. Antiviral Res 43 (1999) 55-63
    • (1999) Antiviral Res , vol.43 , pp. 55-63
    • Arany, I.1    Tyring, S.K.2    Stanley, M.A.3
  • 15
    • 0036008014 scopus 로고    scopus 로고
    • Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway
    • Hemmi H., Kaisho T., Takeuchi O., et al. Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway. Nat Immunol 3 (2002) 196-200
    • (2002) Nat Immunol , vol.3 , pp. 196-200
    • Hemmi, H.1    Kaisho, T.2    Takeuchi, O.3
  • 16
    • 0026494599 scopus 로고
    • Serological assays for the detection of HPV antibodies
    • Munoz N., Bosch F.X., Shah K.V., and Meheus A. (Eds), IARC Scientific Publications, Lyon
    • Galloway D.A. Serological assays for the detection of HPV antibodies. In: Munoz N., Bosch F.X., Shah K.V., and Meheus A. (Eds). The Epidemiology of Human Papillomavirus and Cervical Cancer (1992), IARC Scientific Publications, Lyon 147-161
    • (1992) The Epidemiology of Human Papillomavirus and Cervical Cancer , pp. 147-161
    • Galloway, D.A.1
  • 17
    • 0024407775 scopus 로고
    • Antibodies against the human papillomavirus type 16 early proteins in human sera: correlation of anti-E7 reactivity with cervical cancer
    • Jochmus-Kudielka I., Schneider A., Braun R., et al. Antibodies against the human papillomavirus type 16 early proteins in human sera: correlation of anti-E7 reactivity with cervical cancer. J Natl Cancer Inst 81 (1989) 1698-1704
    • (1989) J Natl Cancer Inst , vol.81 , pp. 1698-1704
    • Jochmus-Kudielka, I.1    Schneider, A.2    Braun, R.3
  • 18
    • 0031975141 scopus 로고    scopus 로고
    • Antibodies against early proteins of human papillomaviruses as diagnostic markers for invasive cervical cancer
    • Meschede W., Zumbach K., Braspenning J., et al. Antibodies against early proteins of human papillomaviruses as diagnostic markers for invasive cervical cancer. J Clin Microbiol 36 (1998) 475-480
    • (1998) J Clin Microbiol , vol.36 , pp. 475-480
    • Meschede, W.1    Zumbach, K.2    Braspenning, J.3
  • 19
    • 0027258818 scopus 로고
    • Prophylactic and therapeutic vaccination against a mucosal papillomavirus
    • Campo M.S., Grindlay G.J., O'Neil B.W., et al. Prophylactic and therapeutic vaccination against a mucosal papillomavirus. J Gen Virol 74 Pt 6 (1993) 945-953
    • (1993) J Gen Virol , vol.74 , Issue.PART 6 , pp. 945-953
    • Campo, M.S.1    Grindlay, G.J.2    O'Neil, B.W.3
  • 20
    • 0025880211 scopus 로고
    • Studies on vaccination against papillomaviruses: prophylactic and therapeutic vaccination with recombinant structural proteins
    • Jarrett W.F., Smith K.T., O'Neil B.W., et al. Studies on vaccination against papillomaviruses: prophylactic and therapeutic vaccination with recombinant structural proteins. Virology 184 (1991) 33-42
    • (1991) Virology , vol.184 , pp. 33-42
    • Jarrett, W.F.1    Smith, K.T.2    O'Neil, B.W.3
  • 21
    • 0344771067 scopus 로고    scopus 로고
    • HPV6b virus like particles are potent immunogens without adjuvant in man
    • Zhang L.F., Zhou J., Chen S., et al. HPV6b virus like particles are potent immunogens without adjuvant in man. Vaccine 18 (2000) 1051-1058
    • (2000) Vaccine , vol.18 , pp. 1051-1058
    • Zhang, L.F.1    Zhou, J.2    Chen, S.3
  • 22
    • 15844365301 scopus 로고    scopus 로고
    • A recombinant vaccinia virus encoding human papillomavirus types 16 and 18, E6 and E7 proteins as immunotherapy for cervical cancer
    • Borysiewicz L.K., Fiander A., Nimako M., et al. A recombinant vaccinia virus encoding human papillomavirus types 16 and 18, E6 and E7 proteins as immunotherapy for cervical cancer. Lancet 347 (1996) 1523-1527
    • (1996) Lancet , vol.347 , pp. 1523-1527
    • Borysiewicz, L.K.1    Fiander, A.2    Nimako, M.3
  • 23
    • 0027320440 scopus 로고
    • Vaccination with cytotoxic T lymphocyte epitope-containing peptide protects against a tumor induced by human papillomavirus type 16-transformed cells
    • Feltkamp M.C., Smits H.L., Vierboom M.P., et al. Vaccination with cytotoxic T lymphocyte epitope-containing peptide protects against a tumor induced by human papillomavirus type 16-transformed cells. Eur J Immunol 23 (1993) 2242-2249
    • (1993) Eur J Immunol , vol.23 , pp. 2242-2249
    • Feltkamp, M.C.1    Smits, H.L.2    Vierboom, M.P.3
  • 24
    • 6344253201 scopus 로고    scopus 로고
    • Mechanisms of human papillomavirus-induced oncogenesis
    • Munger K., Baldwin A., Edwards K.M., et al. Mechanisms of human papillomavirus-induced oncogenesis. J Virol 78 (2004) 11451-11460
    • (2004) J Virol , vol.78 , pp. 11451-11460
    • Munger, K.1    Baldwin, A.2    Edwards, K.M.3
  • 25
    • 70350086302 scopus 로고    scopus 로고
    • Human papillomaviruses
    • Bloom B.R., and Lambert P.H. (Eds), Academic Press, Amsterdam
    • Gissmann L. Human papillomaviruses. In: Bloom B.R., and Lambert P.H. (Eds). The Vaccine Book (2003), Academic Press, Amsterdam 311-322
    • (2003) The Vaccine Book , pp. 311-322
    • Gissmann, L.1
  • 26
    • 0042945766 scopus 로고    scopus 로고
    • A review of human papillomavirus vaccines: from basic science to clinical trials
    • Berry J.M., and Palefsky J.M. A review of human papillomavirus vaccines: from basic science to clinical trials. Front Biosci 8 (2003) s333-s345
    • (2003) Front Biosci , vol.8
    • Berry, J.M.1    Palefsky, J.M.2
  • 27
    • 0038043426 scopus 로고    scopus 로고
    • Cervical cancer vaccines: recent advances in HPV research
    • Eiben G.L., da Silva D.M., Fausch S.C., et al. Cervical cancer vaccines: recent advances in HPV research. Viral Immunol 16 (2003) 111-121
    • (2003) Viral Immunol , vol.16 , pp. 111-121
    • Eiben, G.L.1    da Silva, D.M.2    Fausch, S.C.3
  • 28
    • 0029010639 scopus 로고
    • Effect of interferon therapy on human papillomavirus copy number in patients with condyloma acuminatum
    • Arany I., Rady P., and Tyring S.K. Effect of interferon therapy on human papillomavirus copy number in patients with condyloma acuminatum. Am J Med Sci 310 (1995) 14-18
    • (1995) Am J Med Sci , vol.310 , pp. 14-18
    • Arany, I.1    Rady, P.2    Tyring, S.K.3
  • 29
    • 34548451979 scopus 로고    scopus 로고
    • Prophylactic vaccination against human papillomavirus infection and disease in women: a systematic review of randomized controlled trials
    • Rambout L., Hopkins L., Hutton B., et al. Prophylactic vaccination against human papillomavirus infection and disease in women: a systematic review of randomized controlled trials. CMAJ 177 (2007) 469-479
    • (2007) CMAJ , vol.177 , pp. 469-479
    • Rambout, L.1    Hopkins, L.2    Hutton, B.3
  • 30
    • 34547912100 scopus 로고    scopus 로고
    • Effect of human papillomavirus 16/18 L1 viruslike particle vaccine among young women with preexisting infection: a randomized trial
    • Hildesheim A., Herrero R., Wacholder S., et al. Effect of human papillomavirus 16/18 L1 viruslike particle vaccine among young women with preexisting infection: a randomized trial. JAMA 298 (2007) 743-753
    • (2007) JAMA , vol.298 , pp. 743-753
    • Hildesheim, A.1    Herrero, R.2    Wacholder, S.3
  • 31
    • 40449129515 scopus 로고    scopus 로고
    • Integration of the HPV16 genome does not invariably result in high levels of viral oncogene transcripts
    • Hafner N., Driesch C., Gajda M., et al. Integration of the HPV16 genome does not invariably result in high levels of viral oncogene transcripts. Oncogene 27 (2008) 1610-1617
    • (2008) Oncogene , vol.27 , pp. 1610-1617
    • Hafner, N.1    Driesch, C.2    Gajda, M.3
  • 32
    • 0037229178 scopus 로고    scopus 로고
    • Endogenous human papillomavirus E6 and E7 proteins differentially regulate proliferation, senescence, and apoptosis in HeLa cervical carcinoma cells
    • DeFilippis R.A., Goodwin E.C., Wu L., et al. Endogenous human papillomavirus E6 and E7 proteins differentially regulate proliferation, senescence, and apoptosis in HeLa cervical carcinoma cells. J Virol 77 (2003) 1551-1563
    • (2003) J Virol , vol.77 , pp. 1551-1563
    • DeFilippis, R.A.1    Goodwin, E.C.2    Wu, L.3
  • 33
    • 0141730323 scopus 로고    scopus 로고
    • siRNA targeting of the viral E6 oncogene efficiently kills human papillomavirus-positive cancer cells
    • Butz K., Ristriani T., Hengstermann A., et al. siRNA targeting of the viral E6 oncogene efficiently kills human papillomavirus-positive cancer cells. Oncogene 22 (2003) 5938-5945
    • (2003) Oncogene , vol.22 , pp. 5938-5945
    • Butz, K.1    Ristriani, T.2    Hengstermann, A.3
  • 34
    • 70350081499 scopus 로고    scopus 로고
    • Human papillomavirus vaccines
    • Meisels A., and Morin C. (Eds), ASCP Press, Chicago
    • Gissmann L. Human papillomavirus vaccines. In: Meisels A., and Morin C. (Eds). Modern Uterine Cytopathology (2007), ASCP Press, Chicago 169-200
    • (2007) Modern Uterine Cytopathology , pp. 169-200
    • Gissmann, L.1
  • 35
    • 36849045276 scopus 로고    scopus 로고
    • Recent advances in strategies for immunotherapy of human papillomavirus-induced lesions
    • Kanodia S., Da Silva D.M., and Kast W.M. Recent advances in strategies for immunotherapy of human papillomavirus-induced lesions. Int J Cancer 122 (2008) 247-259
    • (2008) Int J Cancer , vol.122 , pp. 247-259
    • Kanodia, S.1    Da Silva, D.M.2    Kast, W.M.3
  • 36
    • 0033693269 scopus 로고    scopus 로고
    • Genetic immunization against cervical carcinoma: induction of cytotoxic T lymphocyte activity with a recombinant alphavirus vector expressing human papillomavirus type 16 E6 and E7
    • Daemen T., Pries F., Bungener L., et al. Genetic immunization against cervical carcinoma: induction of cytotoxic T lymphocyte activity with a recombinant alphavirus vector expressing human papillomavirus type 16 E6 and E7. Gene Ther 7 (2000) 1859-1866
    • (2000) Gene Ther , vol.7 , pp. 1859-1866
    • Daemen, T.1    Pries, F.2    Bungener, L.3
  • 37
    • 0036894973 scopus 로고    scopus 로고
    • Safety and immunogenicity of TA-HPV, a recombinant vaccinia virus expressing modified human papillomavirus (HPV)-16 and HPV-18 E6 and E7 genes, in women with progressive cervical cancer
    • Kaufmann A.M., Stern P.L., Rankin E.M., et al. Safety and immunogenicity of TA-HPV, a recombinant vaccinia virus expressing modified human papillomavirus (HPV)-16 and HPV-18 E6 and E7 genes, in women with progressive cervical cancer. Clin Cancer Res 8 (2002) 3676-3685
    • (2002) Clin Cancer Res , vol.8 , pp. 3676-3685
    • Kaufmann, A.M.1    Stern, P.L.2    Rankin, E.M.3
  • 38
    • 0026019131 scopus 로고
    • Skin test for HPV type 16 proteins in cervical intraepithelial neoplasia
    • Hopfl R., Sandbichler M., Sepp N., et al. Skin test for HPV type 16 proteins in cervical intraepithelial neoplasia. Lancet 337 (1991) 373-374
    • (1991) Lancet , vol.337 , pp. 373-374
    • Hopfl, R.1    Sandbichler, M.2    Sepp, N.3
  • 39
    • 0031842496 scopus 로고    scopus 로고
    • Tumor regression in mice following vaccination with human papillomavirus E7 recombinant protein in PROVAX
    • Hariharan K., Braslawsky G., Barnett R.S., et al. Tumor regression in mice following vaccination with human papillomavirus E7 recombinant protein in PROVAX. Int J Oncol 12 (1998) 1229-1235
    • (1998) Int J Oncol , vol.12 , pp. 1229-1235
    • Hariharan, K.1    Braslawsky, G.2    Barnett, R.S.3
  • 40
    • 0037115506 scopus 로고    scopus 로고
    • Both E7 and CpG-oligodeoxynucleotide are required for protective immunity against challenge with human papillomavirus 16 (E6/E7) immortalized tumor cells: involvement of CD4+ and CD8+ T cells in protection
    • Kim T.Y., Myoung H.J., Kim J.H., et al. Both E7 and CpG-oligodeoxynucleotide are required for protective immunity against challenge with human papillomavirus 16 (E6/E7) immortalized tumor cells: involvement of CD4+ and CD8+ T cells in protection. Cancer Res 62 (2002) 7234-7240
    • (2002) Cancer Res , vol.62 , pp. 7234-7240
    • Kim, T.Y.1    Myoung, H.J.2    Kim, J.H.3
  • 41
    • 0035925582 scopus 로고    scopus 로고
    • Clinical studies of human papilloma vaccines in pre-invasive and invasive cancer
    • Adams M., Borysiewicz L., Fiander A., et al. Clinical studies of human papilloma vaccines in pre-invasive and invasive cancer. Vaccine 19 (2001) 2549-2556
    • (2001) Vaccine , vol.19 , pp. 2549-2556
    • Adams, M.1    Borysiewicz, L.2    Fiander, A.3
  • 42
    • 3042723816 scopus 로고    scopus 로고
    • Phase I/II trial of immunogenicity of a human papillomavirus (HPV) type 16 E7 protein-based vaccine in women with oncogenic HPV-positive cervical intraepithelial neoplasia
    • Hallez S., Simon P., Maudoux F., et al. Phase I/II trial of immunogenicity of a human papillomavirus (HPV) type 16 E7 protein-based vaccine in women with oncogenic HPV-positive cervical intraepithelial neoplasia. Cancer Immunol Immunother 53 (2004) 642-650
    • (2004) Cancer Immunol Immunother , vol.53 , pp. 642-650
    • Hallez, S.1    Simon, P.2    Maudoux, F.3
  • 43
    • 84984552535 scopus 로고    scopus 로고
    • Enhancement of vaccinia vaccine potency by linkage of tumor antigen gene to gene encoding calreticulin
    • Hsieh C.J., Kim T.W., Hung C.F., et al. Enhancement of vaccinia vaccine potency by linkage of tumor antigen gene to gene encoding calreticulin. Vaccine 22 (2004) 3993-4001
    • (2004) Vaccine , vol.22 , pp. 3993-4001
    • Hsieh, C.J.1    Kim, T.W.2    Hung, C.F.3
  • 44
    • 0036114412 scopus 로고    scopus 로고
    • Activity of HspE7, a novel immunotherapy, in patients with anogenital warts
    • Goldstone S.E., Palefsky J.M., Winnett M.T., et al. Activity of HspE7, a novel immunotherapy, in patients with anogenital warts. Dis Colon Rectum 45 (2002) 502-507
    • (2002) Dis Colon Rectum , vol.45 , pp. 502-507
    • Goldstone, S.E.1    Palefsky, J.M.2    Winnett, M.T.3
  • 45
    • 36248945563 scopus 로고    scopus 로고
    • Vaccination trial with HPV16 L1E7 chimeric virus-like particles in women suffering from high grade cervical intraepithelial neoplasia (CIN 2/3)
    • Kaufmann A.M., Nieland J.D., Jochmus I., et al. Vaccination trial with HPV16 L1E7 chimeric virus-like particles in women suffering from high grade cervical intraepithelial neoplasia (CIN 2/3). Int J Cancer 121 (2007) 2794-2800
    • (2007) Int J Cancer , vol.121 , pp. 2794-2800
    • Kaufmann, A.M.1    Nieland, J.D.2    Jochmus, I.3
  • 46
    • 0032539564 scopus 로고    scopus 로고
    • Chimeric papillomavirus virus-like particles elicit antitumor immunity against the E7 oncoprotein in an HPV16 tumor model
    • Greenstone H.L., Nieland J.D., de Visser K.E., et al. Chimeric papillomavirus virus-like particles elicit antitumor immunity against the E7 oncoprotein in an HPV16 tumor model. Proc Natl Acad Sci USA 95 (1998) 1800-1805
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 1800-1805
    • Greenstone, H.L.1    Nieland, J.D.2    de Visser, K.E.3
  • 47
    • 43949123577 scopus 로고    scopus 로고
    • Arrangement of L2 within the papillomavirus capsid
    • Buck C.B., Cheng N., Thompson C.D., et al. Arrangement of L2 within the papillomavirus capsid. J Virol 82 (2008) 5190-5197
    • (2008) J Virol , vol.82 , pp. 5190-5197
    • Buck, C.B.1    Cheng, N.2    Thompson, C.D.3
  • 48
    • 0033044742 scopus 로고    scopus 로고
    • Immune response to human papillomavirus 16 L1E7 chimeric virus-like particles: induction of cytotoxic T cells and specific tumor protection
    • Schäfer K., Müller M., Faath S., et al. Immune response to human papillomavirus 16 L1E7 chimeric virus-like particles: induction of cytotoxic T cells and specific tumor protection. Int J Cancer 81 (1999) 881-888
    • (1999) Int J Cancer , vol.81 , pp. 881-888
    • Schäfer, K.1    Müller, M.2    Faath, S.3
  • 49
    • 0037019901 scopus 로고    scopus 로고
    • Enhancement of human papillomavirus (HPV) type 16 E6 and E7-specific T-cell immunity in healthy volunteers through vaccination with TA-CIN, an HPV16 L2E7E6 fusion protein vaccine
    • de Jong A., O'Neill T., Khan A.Y., et al. Enhancement of human papillomavirus (HPV) type 16 E6 and E7-specific T-cell immunity in healthy volunteers through vaccination with TA-CIN, an HPV16 L2E7E6 fusion protein vaccine. Vaccine 20 (2002) 3456-3464
    • (2002) Vaccine , vol.20 , pp. 3456-3464
    • de Jong, A.1    O'Neill, T.2    Khan, A.Y.3
  • 51
    • 0033813525 scopus 로고    scopus 로고
    • A phase I trial of a human papillomavirus (HPV) peptide vaccine for women with high-grade cervical and vulvar intraepithelial neoplasia who are HPV 16 positive
    • Muderspach L., Wilczynski S., Roman L., et al. A phase I trial of a human papillomavirus (HPV) peptide vaccine for women with high-grade cervical and vulvar intraepithelial neoplasia who are HPV 16 positive. Clin Cancer Res 6 (2000) 3406-3416
    • (2000) Clin Cancer Res , vol.6 , pp. 3406-3416
    • Muderspach, L.1    Wilczynski, S.2    Roman, L.3
  • 52
    • 0031712034 scopus 로고    scopus 로고
    • Cell-mediated immunological responses in cervical and vaginal cancer patients immunized with a lipidated epitope of human papillomavirus type 16 E7
    • Steller M.A., Gurski K.J., Murakami M., et al. Cell-mediated immunological responses in cervical and vaginal cancer patients immunized with a lipidated epitope of human papillomavirus type 16 E7. Clin Cancer Res 4 (1998) 2103-2109
    • (1998) Clin Cancer Res , vol.4 , pp. 2103-2109
    • Steller, M.A.1    Gurski, K.J.2    Murakami, M.3
  • 53
    • 0033153564 scopus 로고    scopus 로고
    • Vaccination with HPV16 peptides of patients with advanced cervical carcinoma: clinical evaluation of a phase I-II trial
    • van Driel W.J., Ressing M.E., Kenter G.G., et al. Vaccination with HPV16 peptides of patients with advanced cervical carcinoma: clinical evaluation of a phase I-II trial. Eur J Cancer 35 (1999) 946-952
    • (1999) Eur J Cancer , vol.35 , pp. 946-952
    • van Driel, W.J.1    Ressing, M.E.2    Kenter, G.G.3
  • 54
    • 0036583329 scopus 로고    scopus 로고
    • Ins and outs of clinical trials with peptide-based vaccines
    • Salit R.B., Kast W.M., and Velders M.P. Ins and outs of clinical trials with peptide-based vaccines. Front Biosci 7 (2002) e204-e213
    • (2002) Front Biosci , vol.7
    • Salit, R.B.1    Kast, W.M.2    Velders, M.P.3
  • 55
    • 0036644556 scopus 로고    scopus 로고
    • Established human papillomavirus type 16-expressing tumors are effectively eradicated following vaccination with long peptides
    • Zwaveling S., Ferreira Mota S.C., Nouta J., et al. Established human papillomavirus type 16-expressing tumors are effectively eradicated following vaccination with long peptides. J Immunol 169 (2002) 350-358
    • (2002) J Immunol , vol.169 , pp. 350-358
    • Zwaveling, S.1    Ferreira Mota, S.C.2    Nouta, J.3
  • 56
    • 40549129230 scopus 로고    scopus 로고
    • Phase I immunotherapeutic trial with long peptides spanning the E6 and E7 sequences of high-risk human papillomavirus 16 in end-stage cervical cancer patients shows low toxicity and robust immunogenicity
    • Kenter G.G., Welters M.J., Valentijn A.R., et al. Phase I immunotherapeutic trial with long peptides spanning the E6 and E7 sequences of high-risk human papillomavirus 16 in end-stage cervical cancer patients shows low toxicity and robust immunogenicity. Clin Cancer Res 14 (2008) 169-177
    • (2008) Clin Cancer Res , vol.14 , pp. 169-177
    • Kenter, G.G.1    Welters, M.J.2    Valentijn, A.R.3
  • 57
    • 0036091223 scopus 로고    scopus 로고
    • Encapsulated plasmid DNA treatment for human papillomavirus 16-associated anal dysplasia: a Phase I study of ZYC101
    • Klencke B., Matijevic M., Urban R.G., et al. Encapsulated plasmid DNA treatment for human papillomavirus 16-associated anal dysplasia: a Phase I study of ZYC101. Clin Cancer Res 8 (2002) 1028-1037
    • (2002) Clin Cancer Res , vol.8 , pp. 1028-1037
    • Klencke, B.1    Matijevic, M.2    Urban, R.G.3
  • 58
    • 0031915963 scopus 로고    scopus 로고
    • Microspheres containing plasmid-encoded antigens elicit cytotoxic T-cell responses
    • Hedley M.L., Curley J., and Urban R. Microspheres containing plasmid-encoded antigens elicit cytotoxic T-cell responses. Nat Med 4 (1998) 365-368
    • (1998) Nat Med , vol.4 , pp. 365-368
    • Hedley, M.L.1    Curley, J.2    Urban, R.3
  • 59
    • 0026093142 scopus 로고
    • Immunization against human papillomavirus type 16 tumor cells with recombinant vaccinia viruses expressing E6 and E7
    • Meneguzzi G., Cerni C., Kieny M.P., et al. Immunization against human papillomavirus type 16 tumor cells with recombinant vaccinia viruses expressing E6 and E7. Virology 181 (1991) 62-69
    • (1991) Virology , vol.181 , pp. 62-69
    • Meneguzzi, G.1    Cerni, C.2    Kieny, M.P.3
  • 60
    • 0141619282 scopus 로고    scopus 로고
    • Immunological and clinical responses in women with vulval intraepithelial neoplasia vaccinated with a vaccinia virus encoding human papillomavirus 16/18 oncoproteins
    • Davidson E.J., Boswell C.M., Sehr P., et al. Immunological and clinical responses in women with vulval intraepithelial neoplasia vaccinated with a vaccinia virus encoding human papillomavirus 16/18 oncoproteins. Cancer Res 63 (2003) 6032-6041
    • (2003) Cancer Res , vol.63 , pp. 6032-6041
    • Davidson, E.J.1    Boswell, C.M.2    Sehr, P.3
  • 61
    • 10744220391 scopus 로고    scopus 로고
    • Vaccinia-expressed human papillomavirus 16 and 18 e6 and e7 as a therapeutic vaccination for vulval and vaginal intraepithelial neoplasia
    • Baldwin P.J., van der Burg S.H., Boswell C.M., et al. Vaccinia-expressed human papillomavirus 16 and 18 e6 and e7 as a therapeutic vaccination for vulval and vaginal intraepithelial neoplasia. Clin Cancer Res 9 (2003) 5205-5213
    • (2003) Clin Cancer Res , vol.9 , pp. 5205-5213
    • Baldwin, P.J.1    van der Burg, S.H.2    Boswell, C.M.3
  • 62
    • 2442515370 scopus 로고    scopus 로고
    • Therapeutic vaccination with MVA E2 can eliminate precancerous lesions (CIN 1, CIN 2, and CIN 3) associated with infection by oncogenic human papillomavirus
    • Corona Gutierrez C.M., Tinoco A., Navarro T., et al. Therapeutic vaccination with MVA E2 can eliminate precancerous lesions (CIN 1, CIN 2, and CIN 3) associated with infection by oncogenic human papillomavirus. Hum Gene Ther 15 (2004) 421-431
    • (2004) Hum Gene Ther , vol.15 , pp. 421-431
    • Corona Gutierrez, C.M.1    Tinoco, A.2    Navarro, T.3
  • 63
    • 2442598033 scopus 로고    scopus 로고
    • Immunological responses in women with human papillomavirus type 16 (HPV-16)-associated anogenital intraepithelial neoplasia induced by heterologous prime-boost HPV-16 oncogene vaccination
    • Smyth L.J., Van Poelgeest M.I., Davidson E.J., et al. Immunological responses in women with human papillomavirus type 16 (HPV-16)-associated anogenital intraepithelial neoplasia induced by heterologous prime-boost HPV-16 oncogene vaccination. Clin Cancer Res 10 (2004) 2954-2961
    • (2004) Clin Cancer Res , vol.10 , pp. 2954-2961
    • Smyth, L.J.1    Van Poelgeest, M.I.2    Davidson, E.J.3
  • 64
    • 51349124402 scopus 로고    scopus 로고
    • Clinical development of MVA-based therapeutic cancer vaccines
    • Acres B., and Bonnefoy J.Y. Clinical development of MVA-based therapeutic cancer vaccines. Expert Rev Vaccines 7 (2008) 889-893
    • (2008) Expert Rev Vaccines , vol.7 , pp. 889-893
    • Acres, B.1    Bonnefoy, J.Y.2
  • 65
    • 0344665668 scopus 로고    scopus 로고
    • Antitumor efficacy of Venezuelan equine encephalitis virus replicon particles encoding mutated HPV16 E6 and E7 genes
    • Cassetti M.C., McElhiney S.P., Shahabi V., et al. Antitumor efficacy of Venezuelan equine encephalitis virus replicon particles encoding mutated HPV16 E6 and E7 genes. Vaccine 22 (2004) 520-527
    • (2004) Vaccine , vol.22 , pp. 520-527
    • Cassetti, M.C.1    McElhiney, S.P.2    Shahabi, V.3
  • 66
    • 0035915988 scopus 로고    scopus 로고
    • Mucosal vaccination with a recombinant Salmonella typhimurium expressing human papillomavirus type 16 (HPV16) L1 virus-like particles (VLPs) or HPV16 VLPs purified from insect cells inhibits the growth of HPV16-expressing tumor cells in mice
    • Revaz V., Benyacoub J., Kast W.M., et al. Mucosal vaccination with a recombinant Salmonella typhimurium expressing human papillomavirus type 16 (HPV16) L1 virus-like particles (VLPs) or HPV16 VLPs purified from insect cells inhibits the growth of HPV16-expressing tumor cells in mice. Virology 279 (2001) 354-360
    • (2001) Virology , vol.279 , pp. 354-360
    • Revaz, V.1    Benyacoub, J.2    Kast, W.M.3
  • 67
    • 0032520073 scopus 로고    scopus 로고
    • Immunization with human papillomavirus type 16 (HPV16) oncoprotein-loaded dendritic cells as well as protein in adjuvant induces MHC class I-restricted protection to HPV16-induced tumor cells
    • De Bruijn M.L., Schuurhuis D.H., Vierboom M.P., et al. Immunization with human papillomavirus type 16 (HPV16) oncoprotein-loaded dendritic cells as well as protein in adjuvant induces MHC class I-restricted protection to HPV16-induced tumor cells. Cancer Res 58 (1998) 724-731
    • (1998) Cancer Res , vol.58 , pp. 724-731
    • De Bruijn, M.L.1    Schuurhuis, D.H.2    Vierboom, M.P.3
  • 68
    • 4344614767 scopus 로고    scopus 로고
    • Activation of dendritic cells and induction of T cell responses by HPV 16 L1/E7 chimeric virus-like particles are enhanced by CpG ODN or sorbitol
    • Freyschmidt E.J., Alonso A., Hartmann G., et al. Activation of dendritic cells and induction of T cell responses by HPV 16 L1/E7 chimeric virus-like particles are enhanced by CpG ODN or sorbitol. Antivir Ther 9 (2004) 479-489
    • (2004) Antivir Ther , vol.9 , pp. 479-489
    • Freyschmidt, E.J.1    Alonso, A.2    Hartmann, G.3
  • 69
    • 0030882439 scopus 로고    scopus 로고
    • Generation of in vitro autologous human cytotoxic T-cell response to E7 and HER-2/neu oncogene products using ex-vivo peptide loaded dendritic cells
    • Navabi H., Jasani B., Adams M., et al. Generation of in vitro autologous human cytotoxic T-cell response to E7 and HER-2/neu oncogene products using ex-vivo peptide loaded dendritic cells. Adv Exp Med Biol 417 (1997) 583-589
    • (1997) Adv Exp Med Biol , vol.417 , pp. 583-589
    • Navabi, H.1    Jasani, B.2    Adams, M.3
  • 70
    • 0035871993 scopus 로고    scopus 로고
    • HPV16 L1E7 chimeric virus-like particles induce specific HLA-restricted T cells in humans after in vitro vaccination
    • Kaufmann A.M., Nieland J., Schinz M., et al. HPV16 L1E7 chimeric virus-like particles induce specific HLA-restricted T cells in humans after in vitro vaccination. Int J Cancer 92 (2001) 285-293
    • (2001) Int J Cancer , vol.92 , pp. 285-293
    • Kaufmann, A.M.1    Nieland, J.2    Schinz, M.3
  • 71
    • 0033056681 scopus 로고    scopus 로고
    • + lymphocytes by E7-pulsed autologous dendritic cells in patients with human papillomavirus type 16- and 18-positive cervical cancer
    • + lymphocytes by E7-pulsed autologous dendritic cells in patients with human papillomavirus type 16- and 18-positive cervical cancer. J Virol 73 (1999) 5402-5410
    • (1999) J Virol , vol.73 , pp. 5402-5410
    • Santin, A.D.1    Hermonat, P.L.2    Ravaggi, A.3
  • 72
    • 0141528515 scopus 로고    scopus 로고
    • Dendritic cell-based tumor vaccine for cervical cancer II: results of a clinical pilot study in 15 individual patients
    • Ferrara A., Nonn M., Sehr P., et al. Dendritic cell-based tumor vaccine for cervical cancer II: results of a clinical pilot study in 15 individual patients. J Cancer Res Clin Oncol 129 (2003) 521-530
    • (2003) J Cancer Res Clin Oncol , vol.129 , pp. 521-530
    • Ferrara, A.1    Nonn, M.2    Sehr, P.3
  • 73
    • 0037198442 scopus 로고    scopus 로고
    • Vaccination with HPV-18 E7-pulsed dendritic cells in a patient with metastatic cervical cancer
    • Santin A.D., Bellone S., Gokden M., et al. Vaccination with HPV-18 E7-pulsed dendritic cells in a patient with metastatic cervical cancer. N Engl J Med 346 (2002) 1752-1753
    • (2002) N Engl J Med , vol.346 , pp. 1752-1753
    • Santin, A.D.1    Bellone, S.2    Gokden, M.3


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