Human papillomavirus virus-like particles do not activate Langerhans cells: A possible immune escape mechanism used by human papillomaviruses

Journal of Immunology

Volumn 169, Issue 6, 2002, Pages 3242-3249

  Fausch, Steven C ^a   Da Silva, Diane M ^a   Rudolf, Michael P ^a   Kast, W Martin ^a  

^a LOYOLA UNIVERSITY HEALTH SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMICAL MARKER; INTERLEUKIN 12;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN PRESENTING CELL; ARTICLE; CELL ACTIVATION; CELL MIGRATION; CONTROLLED STUDY; CYTOKINE RELEASE; DENDRITIC CELL; FEMALE; HUMAN; HUMAN CELL; IMMUNE RESPONSE; INFLAMMATION; INTERNALIZATION; LANGERHANS CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; VIRUS IMMUNITY; VIRUS PARTICLE; WART VIRUS;

EID: 0037105486     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.169.6.3242     Document Type: Article

References (51)

1. Human papillomaviruses in the pathogenesis of anogenital cancer
2. Human papillomavirus is a necessary cause of invasive cervical cancer worldwide
3. Cervical cancer vaccines: Emerging concepts and developments
4. Occasional memory cytotoxic T-cell responses of patients with human papillomavirus type 16-positive cervical lesions against a human leukocyte antigen-A*0201-restricted E7-encoded epitope
5. Immunology of papillomavirus infection
6. Occurrence of IgA and IgG antibodies to select peptides representing human papillomavirus type 16 among cervical cancer cases and controls
7. Papillomavirus L1 major capsid protein self-assembles into virus-like particles that are highly immunogenic
8. Efficient self-assembly of human papillomavirus type 16 L1 and L1-L2 into virus-like particles
9. Chimeric papillomavirus virus-like particles elicit antitumor immunity against the E7 oncoprotein in an HPV16 tumor model
10. HPV6b virus like particles are potent immunogens without adjuvant in man
11. Papillomavirus virus-like particles can deliver defined CTL epitopes to the MHC class I pathway
12. Chimeric papillomavirus virus-like particles induce a murine self-antigen-specific protective and therapeutic antitumor immune response
13. Dendritic cells: Unique leukocyte populations which control the primary immune response
14. Dendritic cells in the T-cell areas of lymphoid organs
15. Dendritic cells and the control of immunity
16. Immunobiology of dendritic cells
17. Dendritic cells acquire antigen from apoptotic cells and induce class I restricted CTLs
18. Consequences of cell death: Exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells
19. Dendritic cell/macrophage precursors capture exogenous antigen for MHC class I presentation by dendritic cells
20. Dendritic cell loss from nonlymphoid tissues after systemic administration of lipopolysaccharide, tumor necrosis factor, and interleukin 1
21. Migration and maturation of Langerhans cells in skin transplants and explants
22. Transforming growth factor β-1 in the presence of granulocyte/macrophage colony-stimulating factor and interleukin-4, induces differentiation of human peripheral blood monocytes into dendritic Langerhans cells
23. + cells-differentiate into Langerhans cells
24. A role for TGFβ1 in Langerhans cell biology: Further characterization of the epidermal Langerhans cell defect in TGFΒ1 null mice
25. Langerin, a novel C-type lectin specific to Langerhans cells, is an endocytic receptor that induces the formation of Birbeck granules
26. Expression of monoclonal antibody HECA-452-defined E-selectin ligands on Langerhans cells in normal and diseased skin
27. Adhesion of epidermal Langerhans cells to keratinocytes mediated by E-cadherin
28. Langerhans cells and the cells of Langerhans cell histiocytosis do not express DC-SIGN
29. Heat shock proteins 70 and 60 share common receptors which are expressed on human monocyte-derived but not epidermal dendritic cells
30. Human dendritic cells are activated by chimeric human papillomavirus type-16 virus-like particles and induce epitope-specific human T cell responses in vitro
31. Physical interaction of human papillomavirus virus-like particles with immune cells
32. Interaction of papillomaviruses with the cell surface
33. Papillomavirus-like particle vaccines for cervical cancer
34. Functional diversity of helper T lymphocytes
35. Regulatory activity of autocrine IL-10 on dendritic cell functions
36. Human CTL epitopes encoded by human papillomavirus type 16 E6 and E7 identified through in vivo and in vitro immunogenicity studies of HLA-A*0201-binding peptides
37. CpG motifs induce Langerhans cell migration in vivo
38. Papillomavirus-like particles
39. Papillomavirus virus-like particles as anticancer vaccines
40. Papillomavirus-like particles induce acute activation of dendritic cells
41. Correlation of T-helper secretory differentiation and types of antigen-presenting cells in squamous intraepithelial lesions of the uterine cervix
42. A computer program for predicting possible cytotoxic T lymphocyte epitopes based on HLA class I peptide-binding motifs
43. The antigen-presenting environment in normal and human papillomavirus (HPV)-related premalignant cervical epithelium
44. Influence of the mucosal epithelium microenvironment on Langerhans cells: Implications for the development of squamous intraepithelial lesions of the cervix
45. 2 in the inhibition of epidermal Langerhans cell migration during schistosomiasis infection
46. Human melanoma cells inhibit the earliest differentiation steps of human Langerhans cell precursors but failed to affect the functional maturation of epidermal Langerhans cells
47. Applications of pox virus vectors to vaccination: An update
48. Vaccinia virus inhibits the maturation of human dendritic cells: A novel mechanism of immune evasion
49. Viral subversion of the immune system
50. One step ahead of the game: Viral immunomodulatory molecules
51. A comparison of viral immune escape strategies targeting the MHC class I assembly pathway