Isolation and characterization of a high affinity peptide inhibitor of ClC-2 chloride channels

Journal of Biological Chemistry

Volumn 284, Issue 38, 2009, Pages 26051-26052

  Thompson, Christopher H ^a,e   Olivetti, Pedro R ^a   Fuller, Matthew D ^a,b,f   Freeman, Cody S ^a   McMaster, Denis ^d   French, Robert J ^d   Pohl, Jan ^b,g   Kubanek, Julia ^a   MaCarty, Nael A ^a,c,h  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^b EMORY UNIVERSITY   (United States)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF CALGARY   (Canada)

^e VANDERBILT UNIVERSITY   (United States)

^f UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^g CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^h NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AFFINITY INHIBITORS; CATION CHANNELS; CHANNEL ACTIVATION; CHLORIDE CHANNELS; EPITHELIAL TRANSPORT; EXCITABLE CELLS; HIGH AFFINITY; HIGH-AFFINITY PEPTIDES; INHIBITORY EFFECT; ISOLATION AND CHARACTERIZATION; MEMBRANE POTENTIALS; OPEN CHANNELS; PEPTIDE TOXIN; PROTEIN FAMILY; VOLTAGE-GATED POTASSIUM CHANNELS;

AMINES; PEPTIDES; TOXIC MATERIALS;

CHLORINE COMPOUNDS;

CHLORIDE CHANNEL; CHLORIDE CHANNEL BLOCKING AGENT; GATX2 TOXIN; PROTEIN CIC 2; SCORPION VENOM; UNCLASSIFIED DRUG; AGENTS AFFECTING WATER, MOLECULE OR ION TRANSPORT; BACTERIAL PROTEIN; CLC 2 CHLORIDE CHANNELS; CLC-2 CHLORIDE CHANNELS; GATX2 PROTEIN, LEIURUS QUINQUESTRIATUS HEBRAEUS;

ARTICLE; BINDING AFFINITY; CHANNEL GATING; MOLECULAR PROBE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN STRUCTURE; PROTEOMICS; TOXIN ANALYSIS; TOXIN STRUCTURE; ANIMAL; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; HUMAN; ISOLATION AND PURIFICATION; METABOLISM; SCORPION; STRUCTURE ACTIVITY RELATION; XENOPUS LAEVIS;

BACTERIA (MICROORGANISMS); EUKARYOTA; LEIURUS QUINQUESTRIATUS HEBRAEUS;

ANIMALS; BACTERIAL PROTEINS; CHLORIDE CHANNELS; HUMANS; ION CHANNEL GATING; MEMBRANE TRANSPORT MODULATORS; SCORPION VENOMS; SCORPIONS; STRUCTURE-ACTIVITY RELATIONSHIP; XENOPUS LAEVIS;

EID: 70350028675     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.031724     Document Type: Article

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