The cardioprotective effects of zileuton, a 5-lipoxygenase inhibitor, are mediated by COX-2 via activation of PKCδ

Cellular Signalling

Volumn 22, Issue 1, 2010, Pages 80-87

  Kwak, Hyun Jeong ^a   Park, Kyoung Mi ^a   Choi, Hye Eun ^a   Lim, Hyun Joung ^a   Park, Jin Hee ^a   Park, Hyun Young ^a  

^a Korea National Institute of Health   (South Korea)

Author keywords

5 Lipoxygenase inhibitor; Cyclooxygenase 2; Protein kinase C

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; CYCLOOXYGENASE 2; LIPOXYGENASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE 1; PROSTAGLANDIN E2; PROTEIN KINASE B; PROTEIN KINASE C DELTA; SMALL INTERFERING RNA; ZILEUTON;

ANIMAL CELL; ANIMAL CELL CULTURE; APOPTOSIS; ARTICLE; BIOSYNTHESIS; CELL ISOLATION; CELL NUCLEUS; CELL VIABILITY; CONTROLLED STUDY; CYTOSOL; CYTOTOXICITY; DRUG EFFECT; ENZYME ACTIVATION; ENZYME INDUCTION; ENZYME INHIBITION; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART PROTECTION; IMMUNOFLUORESCENCE; IN VITRO STUDY; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; ARACHIDONATE 5-LIPOXYGENASE; CELL SURVIVAL; CELLS, CULTURED; CYCLOOXYGENASE 2; CYTOPROTECTION; DINOPROSTONE; ENZYME ACTIVATION; HYDROGEN PEROXIDE; HYDROXYUREA; LIPOXYGENASE INHIBITORS; MAP KINASE SIGNALING SYSTEM; MYOCYTES, CARDIAC; PROTEIN KINASE C-DELTA; RATS;

RATTUS;

EID: 70349979503     PISSN: 08986568     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellsig.2009.09.014     Document Type: Article

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