Cardioprotective effects of anesthetic preconditioning in rats with ischemia-reperfusion injury: Propofol versus isoflurane

Journal of Zhejiang University: Science B

Volumn 10, Issue 10, 2009, Pages 740-747

  Tao, Xing ^a   Lu, Ling Qiao ^b   Xu, Qing ^b   Li, Shu Ren ^a   Lin, Mao Tsun ^c  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

^c CHI MEI MEDICAL CENTER   (Taiwan)

Author keywords

Anesthetic; Apoptosis; Heart; Isoflurane; Propofol

Indexed keywords

ISOFLURANE; PROPOFOL; TROPONIN T;

ANESTHESIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL COUNT; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; DRUG MECHANISM; HEART INFARCTION; HEART INFARCTION PREVENTION; HEART INFARCTION SIZE; HEART MUSCLE ISCHEMIA; HEART PROTECTION; HEMODYNAMIC PARAMETERS; MALE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION INJURY;

ANESTHETICS, INHALATION; ANESTHETICS, INTRAVENOUS; ANIMALS; APOPTOSIS; CARDIOTONIC AGENTS; DRUG INTERACTIONS; HEMODYNAMICS; ISCHEMIC PRECONDITIONING, MYOCARDIAL; ISOFLURANE; MALE; MYOCARDIAL INFARCTION; PROPOFOL; RATS; RATS, WISTAR; TROPONIN T;

RATTUS; RATTUS NORVEGICUS;

EID: 70349952402     PISSN: 16731581     EISSN: 18621783     Source Type: Journal    
DOI: 10.1631/jzus.B0920119     Document Type: Article

References (42)

1. Aarts, L., van der, Hee R., Dekker, I., de Jong, J., Langemeijer, H., Bast, A., 1995. The widely used anesthetic agent propofol can replace alpha-tocopherol as an antioxidant. FEBS Lett., 357(1):83-85. [doi:10.1016/0014-5793(94)01337-Z]
2. Ambrosio, G., Zweier, J.L., Duilio, C., Kuppusamy, P., Santoro, G., Elia, P.P., Tritto, I., Cirillo, P., Condorelli, M., Chiariello, M., 1993. Evidence that mitochondrial respiration is a source of potentially toxic oxygen free radicals in intact rabbit hearts subjected to ischemia and reflow. J. Biol. Chem., 268(25):18532-18541.
3. Annecke, T., Kubitz, J.C., Kahr, S., Hilberath, J.M., Langer, K., Kemming, G.I., Rehm, M., Bittmann, I., Conzen, P.F., 2007. Effects of sevoflurane and propofol on ischaemia-reperfusion injury after thoracic-aortic occlusion in pigs. Br. J. Anaesth., 98(5):581-590. [doi:10.1093/bja/aem049]
4. Baines, C.P., Cohen, M.V., Downey, J.M., 1999. Signal transduction in ischemic preconditioning: The role of kinases and mitochondrial K(ATP) channels. J. Cardiovasc. Electrophysiol., 10(5):741-754. [doi:10.1111/ j.1540-8167.1999.tb00251.x]
5. Belhomme, D., Peynet, J., Louzy, M., Launay, J.M., Kitakaze, M., Menasché, P., 1999. Evidence for preconditioning by isoflurane in coronary artery bypass graft surgery. Circulation, 100(19 Suppl.):11340-11344.
6. Bolli, R., Patel, B.S., Jeroudi, M.O., Lai, E.K., McCay, P.B., 1988. Demonstration of free radical generation in "stunned" myocardium of intact dogs with the use of the spin trap alpha-phenyl N-tert-butyl nitrone. J. Clin. Invest., 82(2):476-485.[doi:10.1172/ JCI113621]
7. Cason, B.A., Gamperl, A.K., Slocum, R.E., Hickey, R.F., 1997. Anesthetic-induced preconditioning: Previous administration of isoflurane decreases myocardial infarct size in rabbits. Anesthesiology, 87(5):1182-1190. [doi:10.1097/00000542-199711000-00023]
8. Choi, S.U., Lee, H.W., Lim, H.J., Yoon, S.M., Chang, S.H., 2007. The effects of propofol on cardiac function after 4 hours of cold cardioplegia and reperfusion. J. Cardiothorac. Vasc. Anesth., 21(5):678-682. [doi:10.1053/j.jvca.2006.12.020]
9. Conzen, P.F., Fischer, S., Detter, C., Peter, K., 2003. Sevoflurane provides greater protection of the myocardium than propofol in patients undergoing off-pump coronary artery bypass surgery. Anesthesiology, 99(4):826-833. [doi:10.1097/00000542-200310000-00013]
10. de Hert, S.G., ten Broecke, P.W., Mertens, E., van Sommeren, E.W., de Blier, I.G., Stockman, B.A., Rodrigus, I.E., 2002. Sevoflurane but not propofol preserves myocardial function in coronary surgery patients. Anesthesiology, 97(1):42-49. [doi:10.1097/00000542-200207000-00007]
11. de Hert, S.G., van der Linden, P.J., Cromheecke, S., Meeus, R., Nelis, A., van Reeth, V., ten Broecke, P.W., de Blier, I.G., Stockman, B.A., Rodrigus, I.E., 2004. Cardioprotective properties of sevoflurane in patients undergoing coronary surgery with cardiopulmonary bypass are related to the modalities of its administration. Anesthesiology, 101(2):299-310. [doi:10.1097/00000542-200408000-00009]
12. Duranteau, J., Chandel, N.S., Kulisz, A., Shao, Z., Schumacker, P.T., 1998. Intracellular signaling by reactive oxygen species during hypoxia in cardiomyocytes. J. Biol. Chem., 273(19):11619-11624. [doi:10.1074/ jbc.273.19.11619]
13. Ebel, D., Schlack, W., Comfere, T., Preckel, B., Thamer, V., 1999. Effect of propofol on reperfusion injury after regional ischaemia in the isolated rat heart. Br. J. Anaesth., 83(6):903-908.
14. 2+- and phospholipid-independent activation of protein kinase C by selective oxidative modification of the regulatory domain. Proc. Natl. Acad. Sci. USA, 86(17):6758-6762. [doi:10.1073/pnas.86.17.6758]
15. Haroun-Bizri, S., Khoury, S.S., Chehab, I.R., Kassas, C.M., Baraka, A., 2001. Does isoflurane optimize myocardial protection during cardiopulmonary bypass? J. Cardiothorac. Vasc. Anesth., 15(4):418-421. [doi:10.1053/jcan.2001.24954]
16. Ismaeil, M.S., Tkachenko, I., Gamperl, A.K., Hickey, R.F., Cason, B.A., 1999. Mechanisms of isoflurane-induced myocardial preconditioning in rabbits. Anesthesiology, 90(3):812-821. [doi:10.1097/ 00000542-199903000-00024]
17. Kersten, J.R., Schmeling, T.J., Hettrick, D.A., Pagel, P.S., Gross, G.J., Warltier, D.C., 1996. Mechanism of myocardial protection by isoflurane. Role of adenosine triphosphate-regulated potassium (KATP) channels. Anesthesiology, 85(4):794-807. [doi:10.1097/ 00000542-199610000-00015]
18. Kersten, J.R., Schmeling, T.J., Pagel, P.S., Gross, G.J., Warltier, D.C., 1997. Isoflurane mimics ischemic preconditioning via activation of K(ATP) channels: Reduction of myocardial infarct size with an acute memory. Anesthesiology, 87(2):361-370.[doi:10.1097/ 00000542-199708000-00024]
19. Ko, S.H., Yu, C.W., Lee, S.K., Choe, H., Chung, M.J., Kwak, Y.G., Chae, S.W., Song, H.S., 1997. Propofol attenuates ischemia-reperfusion injury in the isolated rat heart. Anesth. Analg., 85(4):719-724. [doi:10.1097/ 00000539-199710000-00002]
20. Kokita, N., Hara, A., 1996. Propofol attenuates hydrogen peroxide-induced mechanical and metabolic derangements in the isolated rat heart. Anesthesiology, 84(1): 117-127. [doi:10.1097/ 00000542-199601000-00014]
21. Kokita, N., Hara, A., Abiko, Y., Arakawa, J., Hashizume, H., Namiki, A., 1998. Propofol improves functional and metabolic recovery in ischemic reperfused isolated rat hearts. Anesth. Analg., 86(2):252-258. [doi:10.1097/00000539-199802000-00006]
22. Kowaltowski, A.J., Seetharaman, S., Paucek, P., Garlid, K.D., 2001. Bioenergetic consequences of opening the ATPsensitive K(+) channel of heart mitochondria. Am. J. Physiol Heart Circ. Physiol., 280(2):H649-H657.
23. Ludwig, L.M., Tanaka, K., Eells, J.T., Weihrauch, D., Pagel, P.S., Kersten, J.R., Warltier, D.C., 2004. Preconditioning by isoflurane is mediated by reactive oxygen species generated from mitochondrial electron transport chain complex III. Anesth. Analg., 99(5):1308-1315. [doi:10.1213/01.ANE.0000134804.09484.5D]
24. Luo, T., Xia, Z., Ansley, D.M., Ouyang, J., Granville, D.J., Li, Y., Xia, Z.Y., Zhou, Q.S., Liu, X.Y., 2005. Propofol dose-dependently reduces tumor necrosis factor-alphainduced human umbilical vein endothelial cell apoptosis: Effects on Bcl-2 and Bax expression and nitric oxide generation. Anesth. Analg., 100(6):1653-1659.[doi:10.1213/ 01.ANE.0000150945.95254.D8]
25. McPherson, B.C., Yao, Z., 2001a. Morphine mimics preconditioning via free radical signals and mitochondrial K(ATP) channels in myocytes. Circulation, 103(2):290-295.
26. McPherson, B.C., Yao, Z., 2001b. Signal transduction of opioid-induced cardioprotection in ischemia-reperfusion. Anesthesiology, 94(6):1082-1088. [doi:10.1097/00000542-200106000-00024]
27. Mullenheim, J., Ebel, D., Frassdorf, J., Preckel, B., Thamer, V., Schlack, W., 2002. Isoflurane preconditions myocardium against infarction via release of free radicals. Anesthesiology, 96(4):934-940. [doi:10.1097/00000542-200204000-00022]
28. Novalija, E., Fujita, S., Kampine, J.P., Stowe, D.F., 1999. Sevoflurane mimics ischemic preconditioning effects on coronary flow and nitric oxide release in isolated hearts. Anesthesiology, 91(3):701-712. [doi:10.1097/00000542-199909000-00023]
29. Piriou, V., Chiari, P., Knezynski, S., Bastien, O., Loufoua, J., Lehot, J.J., Foex, P., Annat, G., Ovize, M., 2000. Prevention of isoflurane-induced preconditioning by 5-hydroxydecanoate and gadolinium: possible involvement of mitochondrial adenosine triphosphate-sensitive potassium and stretch-activated channels. Anesthesiology, 93(3):756-764. [doi:10.1097/00000542-200009000-00025]
30. Quasha, A.L., Eger, E.I., Tinker, J.H., 1980. Determination and application of MAC. Anesthesiology, 53(4):315-334. [doi:10.1097/ 00000542-198010000-00008]
31. Roscoe, A.K., Christensen, J.D., Lynch III, C., 2000. Isoflurane, but not halothane, induces protection of human myocardium via adenosine A1 receptors and adenosine triphosphate-sensitive potassium channels. Anesthesiology, 92(6):1692-1701. [doi:10.1097/00000542-200006000-00029]
32. Sayin, M.M., Ozatamer, O., Tasoz, R., Kilinc, K., Unal, N., 2002. Propofol attenuates myocardial lipid peroxidation during coronary artery bypass grafting surgery. Br. J. Anaesth., 89(2):242-246. [doi:10.1093/ bja/aef173]
33. Scarabelli, T., Stephanou, A., Rayment, N., Pasini, E., Comini, L., Curello, S., Ferrari, R., Knight, R., Latchman, D., 2001. Apoptosis of endothelial cells precedes myocyte cell apoptosis in ischemia/ reperfusion injury. Circulation, 104(3):253-256.
34. Tanaka, K., Weihrauch, D., Kehl, F., Ludwig, L.M., LaDisa, J.F.Jr., Kersten, J.R., Pagel, P.S., Warltier, D.C., 2002. Mechanism of preconditioning by isoflurane in rabbits: A direct role for reactive oxygen species. Anesthesiology, 97(6):1485-1490. [doi:10.1097/ 00000542-200212000-00021]
35. Tanaka, K., Weihrauch, D., Ludwig, L.M., Kersten, J.R., Pagel, P.S., Warltier, D.C., 2003. Mitochondrial adenosine triphosphate-regulated potassium channel opening acts as a trigger for isoflurane-induced preconditioning by generating reactive oxygen species. Anesthesiology, 98(4):935-943. [doi:10.1097/00000542-200304000-00021]
36. Toller, W.G., Kersten, J.R., Gross, E.R., Pagel, P.S., Warltier, D.C., 2000. Isoflurane preconditions myocardium against infarction via activation of inhibitory guanine nucleotide binding proteins. Anesthesiology, 92(5):1400-1407. [doi:10.1097/00000542-200005000-00031]
37. Tomasdottir, H., Hjartarson, H., Ricksten, A., Wasslavik, C., Bengtsson, A., Ricksten, S.E., 2003. Tumor necrosis factor gene polymorphism is associated with enhanced systemic inflammatory response and increased cardiopulmonary morbidity after cardiac surgery. Anesth. Analg., 97(4):944-949. [doi:10.1213/01.ANE.0000078574.76915.11]
38. van Empel, V.P., Bertrand, A.T., Hofstra, L., Crijns, H.J., Doevendans, P.A., de Windt, L.J., 2005. Myocyte apoptosis in heart failure. Cardiovasc. Res., 67(1):21-29. [doi:10.1016/j.cardiores.2005.04.012]
39. Warltier, D.C., al Wathiqui, M.H., Kampine, J.P., Schmeling, W.T., 1988. Recovery of contractile function of stunned myocardium in chronically instrumented dogs is enhanced by halothane or isoflurane. Anesthesiology, 69(4):552-565. [doi:10.1097/00000542-198810000-00016]
40. Xia, Z., Godin, D.V., Ansley, D.M., 2004. Application of high-dose propofol during ischemia improves postischemic function of rat hearts: effects on tissue antioxidant capacity. Can. J. Physiol. Pharmacol., 82(10):919-926. [doi:10.1139/y04-097]
41. Xia, Z., Huang, Z., Ansley, D.M., 2006. Large-dose propofol during cardiopulmonary bypass decreases biochemical markers of myocardial injury in coronary surgery patients: A comparison with isoflurane. Anesth. Analg., 103(3):527-532. [doi:10.1213/01.ane.0000230612.29452.a6]
42. Zweier, J.L., Flaherty, J.T., Weisfeldt, M.L., 1987. Direct measurement of free radical generation following reperfusion of ischemic myocardium. Proc. Natl. Acad. Sci. USA, 84(5):1404-1407. [doi:10.1073/pnas.84.5.1404]