메뉴 건너뛰기




Volumn 24, Issue 10, 2009, Pages 1709-1718

Association of the aromatase gene alleles with BMD: Epidemiological and functional evidence

Author keywords

Aromatase; CEBP ; Gene expression; Osteoporosis; Polymorphisms

Indexed keywords

AROMATASE; CCAAT ENHANCER BINDING PROTEIN BETA; LUCIFERASE;

EID: 70349915716     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.090404     Document Type: Article
Times cited : (35)

References (50)
  • 1
    • 84967614664 scopus 로고    scopus 로고
    • Sex steroids and the construction and conservation of the adult skeleton
    • DOI 10.1210/er.23.3.279
    • Riggs BL, Khosla S, Melton LJ III 2002 Sex steroids and the construction and conservation of adult skeleton. Endocr Rev 23:279-302. (Pubitemid 34651948)
    • (2002) Endocrine Reviews , vol.23 , Issue.3 , pp. 279-302
    • Riggs, B.L.1    Khosla, S.2    Melton III, L.J.3
  • 2
    • 33748680524 scopus 로고    scopus 로고
    • Genetic regulation of bone mass and susceptibility to osteoporosis
    • DOI 10.1101/gad.1449506
    • Ralston SH, de Crombrugghe B 2006 Genetic regulation of bone mass and susceptibility to osteoporosis. Genes Dev 20:2492-2506. (Pubitemid 44396835)
    • (2006) Genes and Development , vol.20 , Issue.18 , pp. 2492-2506
    • Ralston, S.H.1    De Crombrugghe, B.2
  • 6
    • 0036546523 scopus 로고    scopus 로고
    • Mechanisms in tissue-specific regulation of estrogen biosynthesis in humans
    • DOI 10.1016/S1043-2760(02)00567-2, PII S1043276002005672
    • Kamat A, Hinshelwood MM, Murry BA, Mendelson CR 2002 Mechanisms in tissue-specific regulation of estrogen biosynthesis in humans. Trends Endocrinol Metab 13:122-128. (Pubitemid 36734002)
    • (2002) Trends in Endocrinology and Metabolism , vol.13 , Issue.3 , pp. 122-128
    • Kamat, A.1    Hinshelwood, M.M.2    Murry, B.A.3    Mendelson, C.R.4
  • 7
    • 0033771003 scopus 로고    scopus 로고
    • Role of aromatase in sex steroid action
    • Simpson ER 2000 Role of aromatase in sex steroid action. J Mol Endocrinol 25:1549-1556.
    • (2000) J Mol Endocrinol , vol.25 , pp. 1549-1556
    • Simpson, E.R.1
  • 8
    • 0034751150 scopus 로고    scopus 로고
    • Genetics of endocrine disease: A highly complex organization of the regulatory region of the human CYP19 (Aromatase) gene revealed by the human genome project
    • DOI 10.1210/jc.86.10.4600
    • Sebastian S, Bulun SE 2001 A highly complex organization of the regulatory region of the human CYP19 (aromatase) gene revealed by the human genome project. J Clin Endocrinol Metab 86:4600-4602. (Pubitemid 33020491)
    • (2001) Journal of Clinical Endocrinology and Metabolism , vol.86 , Issue.10 , pp. 4600-4602
    • Sebastian, S.1    Bulun, S.E.2
  • 9
    • 33646404613 scopus 로고    scopus 로고
    • Effects of third-generation aromatase inhibitors on bone
    • McCloskey E 2006 Effects of third-generation aromatase inhibitors on bone. Eur J Cancer 42:1044-1051.
    • (2006) Eur J Cancer , vol.42 , pp. 1044-1051
    • McCloskey, E.1
  • 10
    • 0032572929 scopus 로고    scopus 로고
    • Increased bone mass as a result of estrogen therapy in a man with aromatase deficiency
    • DOI 10.1056/NEJM199808273390905
    • Bilezikian JP, Morishima A, Bell J, Grumbach MM 1998 Increased bone mass as a result of estrogen therapy in a man with aromatase deficiency. J Clin Endocrinol Metab 339:599-603. (Pubitemid 28385657)
    • (1998) New England Journal of Medicine , vol.339 , Issue.9 , pp. 599-603
    • Bilezikian, J.P.1    Morishima, A.2    Bell, J.3    Grumbach, M.M.4
  • 13
    • 34247129195 scopus 로고    scopus 로고
    • Polymorphisms in the CYP19 gene that influence bone mineral density
    • DOI 10.2217/14622416.8.4.339
    • Riancho JA 2007 Polymorphisms in the CYP19 gene that influence bone mineral density. Pharmacogenomics 8:339-352. (Pubitemid 46585497)
    • (2007) Pharmacogenomics , vol.8 , Issue.4 , pp. 339-352
    • Riancho, J.A.1
  • 19
    • 0034118493 scopus 로고    scopus 로고
    • Inference of population structure using multilocus genotype data
    • Pritchard JK, Stephens M, Donnelly P 2000 Inference of population structure using multilocus genotype data. Genetics 155:945-959. (Pubitemid 30397141)
    • (2000) Genetics , vol.155 , Issue.2 , pp. 945-959
    • Pritchard, J.K.1    Stephens, M.2    Donnelly, P.3
  • 20
    • 13444269543 scopus 로고    scopus 로고
    • Haploview: Analysis and visualization of LD and haplotype maps
    • DOI 10.1093/bioinformatics/bth457
    • Barrett JC, Fry B, Maller J, Daly MJ 2005 Haploview: Analysis and visualization of LD and haplotype maps. Bioinformatics 21:263-265. (Pubitemid 40202029)
    • (2005) Bioinformatics , vol.21 , Issue.2 , pp. 263-265
    • Barrett, J.C.1    Fry, B.2    Maller, J.3    Daly, M.J.4
  • 22
    • 1842539516 scopus 로고    scopus 로고
    • A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other
    • Nyholt DR 2004 A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other. Am J Hum Genet 74:765-769.
    • (2004) Am J Hum Genet , vol.74 , pp. 765-769
    • Nyholt, D.R.1
  • 27
    • 17444392808 scopus 로고    scopus 로고
    • Association of an aromatase TTTA repeat polymorphism with circulating estrogen, bone structure, and biochemistry in older women
    • DOI 10.1152/ajpendo.00550.2004
    • Dick IM, Devine A, Prince RL 2005 Association of an aromatase TTTA repeat polymorphism with circulating estrogen, bone structure, and biochemistry in older women. Am J Physiol Endocrinol Metab 288:E989-E995. (Pubitemid 40547894)
    • (2005) American Journal of Physiology - Endocrinology and Metabolism , vol.288 , Issue.5
    • Dick, I.M.1    Devine, A.2    Prince, R.L.3
  • 29
    • 12244313027 scopus 로고    scopus 로고
    • Relation of androgen receptor gene polymorphism to bone mineral density and fracture risk in early postmenopausal women during a 5-year randomized hormone replacement therapy trial
    • Salmen T, Heikkinen AM, Mahonen A, Kroger H, Komulainen M, Pallonen H, Saarikoski S, Honkanen R, Maenpaa PH 2003 Relation of androgen receptor gene polymorphism to bone mineral density and fracture risk in early postmenopausal women during a 5-year randomized hormone replacement therapy trial. J Bone Miner Res 18:319-324.
    • (2003) J Bone Miner Res , vol.18 , pp. 319-324
    • Salmen, T.1    Heikkinen, A.M.2    Mahonen, A.3    Kroger, H.4    Komulainen, M.5    Pallonen, H.6    Saarikoski, S.7    Honkanen, R.8    Maenpaa, P.H.9
  • 31
    • 33744957575 scopus 로고    scopus 로고
    • Multilocus analysis of estrogen-related genes in Spanish postmenopausal women suggests an interactive role of ESR1, ESR2 and NRIP1 genes in the pathogenesis of osteoporosis
    • Moron FJ, Mendoza N, Vazquez F, Molero E, Quereda F, Salinas A, Fontes J, Martinez-Astorquiza T, Sanchez-Borrego R, Ruiz A 2006 Multilocus analysis of estrogen-related genes in Spanish postmenopausal women suggests an interactive role of ESR1, ESR2 and NRIP1 genes in the pathogenesis of osteoporosis. Bone 39:213-221.
    • (2006) Bone , vol.39 , pp. 213-221
    • Moron, F.J.1    Mendoza, N.2    Vazquez, F.3    Molero, E.4    Quereda, F.5    Salinas, A.6    Fontes, J.7    Martinez-Astorquiza, T.8    Sanchez-Borrego, R.9    Ruiz, A.10
  • 32
    • 33144477204 scopus 로고    scopus 로고
    • Polymorphisms in the aromatase gene predict areal BMD as a result of affected cortical bone size: The GOOD study
    • DOI 10.1359/JBMR.051026
    • Lorentzon M, Swanson C, Eriksson AL, Mellstrom D, Ohlsson C 2006 Polymorphisms in the aromatase gene predict areal BMD as a result of affected cortical bone size: The GOOD study. J Bone Miner Res 21:332-339. (Pubitemid 43265300)
    • (2006) Journal of Bone and Mineral Research , vol.21 , Issue.2 , pp. 332-339
    • Lorentzon, M.1    Swanson, C.2    Eriksson, A.-L.3    Mellstrom, D.4    Ohlsson, C.5
  • 34
    • 0029002074 scopus 로고
    • Aromatase P450 gene expression in human adipose tissue. Role of a Jak/STAT pathway in regulation of the adipose-specific promoter
    • Zhao Y, Nichols JE, Bulun SE, Mendelson CR, Simpson ER 1995 Aromatase P450 gene expression in human adipose tissue. Role of a Jak/STAT pathway in regulation of the adipose-specific promoter. J Biol Chem 270:16449-16457.
    • (1995) J Biol Chem , vol.270 , pp. 16449-16457
    • Zhao, Y.1    Nichols, J.E.2    Bulun, S.E.3    Mendelson, C.R.4    Simpson, E.R.5
  • 35
  • 42
    • 0029958796 scopus 로고    scopus 로고
    • 3 enhances the enzymatic activity and expression of the messenger ribonucleic acid for aromatase cytochrome P450 synergistically with dexamethasone depending on the vitamin D receptor level in cultured human osteoblasts
    • DOI 10.1210/en.137.5.1860
    • Tanaka S, Haji M, Takayanagi R, Tanaka S, Sugioka Y, Nawata H 1996 1,25-Dihydroxyvitamin D3 enhances the enzymatic activity and expression of the messenger ribonucleic acid for aromatase cytochrome P450 synergistically with dexamethasone depending on the vitamin D receptor level in cultured human osteoblasts. Endocrinology 137: 1860-1869. (Pubitemid 26133962)
    • (1996) Endocrinology , vol.137 , Issue.5 , pp. 1860-1869
    • Tanaka, S.1    Haji, M.2    Takayanagi, R.3    Tanaka, S.4    Sugioka, Y.5    Nawata, H.6
  • 45
    • 0036092958 scopus 로고    scopus 로고
    • Regulation of aromatase P450 expression in endometriotic and endometrial stromal cells by CCAAT/enhancer binding proteins (C/EBPs): Decreased C/EBPbeta in endometriosis is associated with overexpression of aromatase
    • DOI 10.1210/jc.87.5.2336
    • Yang S, Fang Z, Suzuki T, Sasano H, Zhou J, Gurates B, Tamura M, Ferrer K, Bulun S 2002 Regulation of aromatase P450 expression in endometriotic and endometrial stromal cells by CCAAT/enhancer binding proteins (C/EBPs): Decreased C/EBPbeta in endometriosis is associated with overexpression of aromatase. J Clin Endocrinol Metab 87:2336-2345. (Pubitemid 34521528)
    • (2002) Journal of Clinical Endocrinology and Metabolism , vol.87 , Issue.5 , pp. 2336-2345
    • Yang, S.1    Fang, Z.2    Suzuki, T.3    Sasano, H.4    Zhou, J.5    Gurates, B.6    Tamura, M.7    Ferrer, K.8    Bulun, S.9
  • 46
    • 40849100077 scopus 로고    scopus 로고
    • CCAAT/enhancer binding protein beta regulates aromatase expression via multiple and novel cis-regulatory sequences in uterine leiomyoma
    • Ishikawa H, Fencki V, Marsh EE, Yin P, Chen D, Cheng YH, Reisterd S, Lin Z, Bulun SE 2008 CCAAT/enhancer binding protein beta regulates aromatase expression via multiple and novel cis-regulatory sequences in uterine leiomyoma. J Clin Endocrinol Metab 93:981-991.
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 981-991
    • Ishikawa, H.1    Fencki, V.2    Marsh, E.E.3    Yin, P.4    Chen, D.5    Cheng, Y.H.6    Reisterd, S.7    Lin, Z.8    Bulun, S.E.9
  • 48
    • 35748963239 scopus 로고    scopus 로고
    • Genome-wide association with bone mass and geometry in the framingham heart study
    • DOI 10.1186/1471-2350-8-S1-S14
    • Kiel DP, Demissie S, Dupuis J, Lunetta KL, Murabito JM, Karasik D 2007 Genome-wide association with bone mass and geometry in the Framingham Heart Study. BMC Med Genet 8(Suppl 1):S14. (Pubitemid 351958747)
    • (2007) BMC Medical Genetics , vol.8 , Issue.SUPPL. 1
    • Kiel, D.P.1    Demissie, S.2    Dupuis, J.3    Lunetta, K.L.4    Murabito, J.M.5    Karasik, D.6
  • 50
    • 35649020156 scopus 로고    scopus 로고
    • Power analysis for genome-wide association studies
    • Klein RJ 2007 Power analysis for genome-wide association studies. BMC Genet 8:58.
    • (2007) BMC Genet , vol.8 , pp. 58
    • Klein, R.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.