Nucleation capacity and presence of centrioles define a distinct category of centrosome abnormalities that induces multipolar mitoses in cancer cells

Environmental and Molecular Mutagenesis

Volumn 50, Issue 8, 2009, Pages 672-696

  Difilippantonio, Michael J ^a,d   Ghadimi, B Michael ^a   Howard, Tamara ^b   Camps, Jordi ^a   Nguyen, Quang Tri ^a   Ferris, Douglas K ^a   Sackett, Dan L ^c   Ried, Thomas ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b UNIVERSITY OF NEW MEXICO HEALTH SCIENCES CENTER   (United States)

^c EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^d NONE   (United States)

Author keywords

Aneuploidy; Centrosome; Chromosome instability; Gene expression

Indexed keywords

AURORA A KINASE; BRCA1 PROTEIN; CELL NUCLEUS DNA; GAMMA TUBULIN; PERICENTRIN; POLO LIKE KINASE 1;

ANEUPLOIDY; ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CENTRIOLE; CENTROMERE; CENTROSOME; CHROMOSOME ABERRATION; CHROMOSOME TRANSLOCATION; COLORECTAL CARCINOMA; CONTROLLED STUDY; DIPLOIDY; EMBRYO CELL; FIBROBLAST; GENE ACTIVATION; GENE EXPRESSION; GENOMIC INSTABILITY; HEMATOLOGIC MALIGNANCY; HUMAN; HUMAN CELL; INTERPHASE; MICROTUBULE; MITOSIS; MITOSIS SPINDLE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; ONCOGENE; PANCREAS CANCER; SCANNING ELECTRON MICROSCOPY; SOLID TUMOR; STRUCTURE ACTIVITY RELATION; UNINDEXED SEQUENCE;

ANIMALS; CELL LINE, TUMOR; CENTROSOME; COLORECTAL NEOPLASMS; GENE EXPRESSION PROFILING; HUMANS; IMMUNOHISTOCHEMISTRY; MICE; MICROSCOPY, ELECTRON;

EID: 70349898438     PISSN: 08936692     EISSN: 10982280     Source Type: Journal    
DOI: 10.1002/em.20532     Document Type: Article

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