Clean recovery of antioxidant flavonoids from citrus peel: Optimizing an aqueous ultrasound-assisted extraction method

Food Chemistry

Volumn 119, Issue 1, 2010, Pages 81-87

  Londoño Londoño, Julián ^a   Lima, Vânia Rodrigues de ^b   Lara, Oscar ^a   Gil, Andres ^a   Pasa, Tânia Beatriz Crecsynski ^b   Arango, Gabriel Jaime ^a   Pineda, José R Ramirez ^a  

^a UNIVERSIDAD DE ANTIOQUIA   (Colombia)

^b FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

Author keywords

Citrus peel; Flavonoids; HPLC MS; LDL; Ultrasound assisted extraction

Indexed keywords

ANTIOXIDANT; COPPER ION; DIOSMIN; FLAVANONE; FLAVONE; FLAVONOID; GALLIC ACID; HESPERIDIN; NEOHESPERIDIN; NOBILETIN; OXIDIZED LOW DENSITY LIPOPROTEIN; PEROXYNITRITE; PHENOL DERIVATIVE; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ANTIOXIDANT ACTIVITY; ARTICLE; CITRUS FRUIT; ELECTROSPRAY MASS SPECTROMETRY; EXTRACTION; FOOD ANALYSIS; FRUIT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIME (FRUIT); LIPID OXIDATION; METHODOLOGY; NONHUMAN; ORANGE (FRUIT); TANGERINE; ULTRASOUND;

CITRUS; CITRUS RETICULATA;

EID: 70349814405     PISSN: 03088146     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.foodchem.2009.05.075     Document Type: Article

References (30)

1. Berhow, M. T. B., Kanes, K., & Vandercook, C. (1996). Survey of phenolic compounds produced in citrus. In Technical bulletin 1856 (Vol. 158). A.R.S. US Department of Agriculture.
2. Bird R.P., and Draper A.H. Comparative studies on different methods of malondyaldehyde determination. Methods in Enzymology 105 (1984) 295-305
3. Cirico T.L., and Omaye S.T. Additive or synergetic effects of phenolic compounds on human low density lipoprotein oxidation. Food and Chemical Toxicology 44 4 (2006) 510-516
4. Cuyckens F., Ma Y.L., Pocsfalvi G., and Claeys M. Tandem mass spectral strategies for the structural characterisation of flavonoid glycosides. Analysis 28 10 (2000) 888-895
5. De Lima V.R., Morfim M.P., Teixeira A., and Creczynski-Pasa T.B. Relationship between the action of reactive oxygen and nitrogen species on bilayer membranes and antioxidants. Chemistry and Physics of Lipids 132 2 (2004) 197
6. De Lourdes Mata Bilbao M., Andres-Lacueva C., Jauregui O., and Lamuela-Raventos R.M. Determination of flavonoids in a citrus fruit extract by LC-DAD and LC-MS. Food Chemistry 101 4 (2007) 1742
7. de Whalley C.V., Rankin S.M., Hoult J.R., Jessup W., and Leake D.S. Flavonoids inhibit the oxidative modification of low density lipoproteins by macrophages. Biochemical Pharmacology 39 11 (1990) 1743-1750
8. El-Nawawi S.A. Extraction of citrus glucosides. Carbohydrate Polymers 27 1 (1995) 1
9. Esterbauer H., Gebicki J., Puhl H., and Jurgens G. The role of lipid peroxidation and antioxidants in oxidative modification of LDL. Free Radical Biology and Medicine 13 4 (1992) 341-390
10. Grohmann K., Manthey J.A., and Cameron R.G. Acid-catalyzed hydrolysis of hesperidin at elevated temperatures. Carbohydrate Research 328 2 (2000) 141
11. Hollman P.C.H., Bijsman M.N.C.P., van Gameren Y., Cnossen E.P.J., de Vries J.H.M., and Katan M.B. The sugar moiety is a major determinant of the absorption of dietary flavonoid glycosides in man. Free Radical Research 31 6 (1999) 569-573
12. Huck C.W., Huber C.G., Ongania K.-H., and Bonn G.K. Isolation and characterisation of methoxylated flavones in the flowers of Primula veris by liquid chromatography and mass spectrometry. Journal of Chromatography A 870 1-2 (2000) 453
13. Kawaii S., Tomono Y., Katase E., Ogawa K., Nonomura-Nakano M., Nesumi H., et al. Quantitative study of fruit flavonoids in citrus hybrids of King (C. nobilis) and Mukaku Kishu (C. kinokuni). Journal of Agricultural Food Chemistry 49 8 (2001) 3982-3986
14. Kelly E.H., Anthony R.T., and Dennis J.B. Flavonoid antioxidants: Chemistry, metabolism and structure-activity relationships. The Journal of Nutritional Biochemistry 13 10 (2002) 572
15. Kobayashi S., Tanabe S., Sugiyama M., and Konishi Y. Transepithelial transport of hesperetin and hesperidin in intestinal Caco-2 cell monolayers. Biochimica et Biophysica Acta (BBA) - Biomembranes 1778 1 (2008) 33
16. Kurowska E.M., and Manthey J.A. Hypolipidemic effects and absorption of citrus polymethoxylated flavones in hamsters with diet-induced hypercholesterolemia. Journal of Agricultural Food Chemistry 52 10 (2004) 2879-2886
17. Lai H.H., and Yen G.C. Inhibitory effect of isoflavones on peroxynitrite-mediated low-density lipoprotein oxidation. Bioscience Biotechnology and Biochemistry 66 1 (2002) 22-28
18. Lee S.-H., Jeong T.-S., Park Y.B., Kwon Y.-K., Choi M.-S., and Bok S.-H. Hypocholesterolemic effect of hesperetin mediated by inhibition of 3-hydroxy-3-methylgultaryl coenzyme a reductase and acyl coenzyme a: Cholesterol acyltransferase in rats fed high-cholesterol diet. Nutrition Research 19 8 (1999) 1245
19. Londoño J.M.G., Guerrero K., Aristizabal L., and Arango G. Citrus juice inhibits low density lipoprotein oxidation: Relationship between free radical scavenger activity and electrophoretic mobility. Revista Chilena de Nutricion 33 3 (2006) 8
20. Ma Y., Ye X., Hao Y., Xu G., Xu G., and Liu D. Ultrasound-assisted extraction of hesperidin from Penggan (Citrus reticulata) peel. Ultrasonics Sonochemistry 15 3 (2008) 227-232
21. Rice-Evans C.A., Miller N.J., and Paganga G. Structure-antioxidant activity relationships of flavonoids and phenolic acids. Free Radical Biology and Medicine 20 7 (1996) 933-956
22. Rio J.A.D., Fuster M.D., Sabater F., Porras I., Garcia-Lidon A., and Ortuno A. Selection of citrus varieties highly productive for the neohesperidin dihydrochalcone precursor. Food Chemistry 59 3 (1997) 433
23. Schieber A., Stintzing F.C., and Carle R. By-products of plant food processing as a source of functional compounds - Recent developments. Trends in Food Science and Technology 12 11 (2001) 401
24. Shishehbor M.H., Aviles R.J., Brennan M.L., Fu X., Goormastic M., Pearce G.L., et al. Association of nitrotyrosine levels with cardiovascular disease and modulation by statin therapy. Jama 289 13 (2003) 1675-1680
25. Valensi P.E., Behar A., de Champvallins M.M., Attalah M., Boulakia F.C., and Attali J.R. Effects of a purified micronized flavonoid fraction on capillary filtration in diabetic patients. Diabetic Medicine 13 10 (1996) 882-888
26. Vinatoru M. An overview of the ultrasonically assisted extraction of bioactive principles from herbs. Ultrasonics Sonochemistry 8 3 (2001) 303-313
27. Weber B., Hartmann B., Stockigt D., Schreiber K., Roloff M., Bertram H.-J., et al. Liquid chromatography/mass spectrometry and liquid chromatography/nuclear magnetic resonance as complementary analytical techniques for unambiguous identification of polymethoxylated flavones in residues from molecular distillation of orange peel oils (Citrus sinensis). Journal of Agricultural and Food Chemistry 54 2 (2006) 274-278
28. Williamson G., Plumb G.W., and Garcia-Conesa M.T. Glycosylation, esterification and polymerization of flavonoids and hydroxycinnamates: Effects on antioxidant properties. Basic Life Science 66 (1999) 483-494
29. Witztum J.L., and Steinberg D. Role of oxidized low density lipoprotein in atherogenesis. Journal of Clinical Investigation 88 6 (1991) 1785-1792
30. Yeh C.C., Kao S.J., Lin C.C., Wang S.D., Liu C.J., and Kao S.T. The immunomodulation of endotoxin-induced acute lung injury by hesperidin in vivo and in vitro. Life Science 80 20 (2007) 1821-1831