Development of peptide receptor binding assays: Methods to avoid false negatives

Regulatory Peptides

Volumn 158, Issue 1-3, 2009, Pages 97-102

  Vergote, Valentijn ^a   Van Dorpe, Sylvia ^a   Verbeken, Mathieu ^a   Burvenich, Christian ^a   Van de Wiele, Christophe ^b   Banks, William A ^c   De Spiegeleer, Bart ^a  

^a GHENT UNIVERSITY   (Belgium)

^b GHENT UNIVERSITY   (Belgium)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Bacitracin; Design of experiments (DOE); False negative results; In vitro receptor drug interaction; Peptides

Indexed keywords

ALBUMIN; BACITRACIN; BOVINE SERUM ALBUMIN; IODINE 125; POLYETHYLENEIMINE; PROTEINASE INHIBITOR; RADIOLIGAND; VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR;

ADSORPTION KINETICS; ANALYTIC METHOD; ANIMAL TISSUE; ARTICLE; BINDING ASSAY; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; EXPERIMENTAL DESIGN; FALSE NEGATIVE RESULT; INCUBATION TIME; LUNG HOMOGENATE; MALE; NONHUMAN; PEPTIDE ANALYSIS; PRIORITY JOURNAL; PROTEIN BINDING; RAT; RECEPTOR BINDING;

AMINO ACID SEQUENCE; ANIMALS; FALSE NEGATIVE REACTIONS; FILTRATION; LIGANDS; LUNG; MALE; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, PEPTIDE; VASOACTIVE INTESTINAL PEPTIDE;

EID: 70349807816     PISSN: 01670115     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.regpep.2009.08.006     Document Type: Article

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