LC-UV/MS characterization and DOE optimization of the iodinated peptide obestatin

Journal of Pharmaceutical and Biomedical Analysis

Volumn 46, Issue 1, 2008, Pages 127-136

  Vergote, Valentijn ^a   Baert, Bram ^a   Vandermeulen, Eva ^a   Peremans, Kathelijne ^a   van Bree, Henri ^a   Slegers, Guido ^a   Burvenich, Christian ^a   De Spiegeleer, Bart ^a  

^a GHENT UNIVERSITY   (Belgium)

Author keywords

Chloramine T; Design of experiments (DOE); ESI ion trap MS MS; Iodo Gen ; Lactoperoxidase; Obestatin; Peptide iodination

Indexed keywords

HISTIDINE; IODIDE; IODINE 125; LACTOPEROXIDASE; OBESTATIN; PEPTIDE; TOSYLCHLORAMIDE SODIUM; TYROSINE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL INTERACTION; CHEMICAL PARAMETERS; CHEMICAL REACTION; CHROMATOGRAPHY; ELECTROPHILIC STRESS; EXPERIMENTAL DESIGN; IODINATION; ION TRAP MASS SPECTROMETRY; ISOMER; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; RADIOIODINATION; SEPARATION TECHNIQUE; SYNTHESIS; ULTRAVIOLET RADIATION;

ANIMALS; CHLORAMINES; CHROMATOGRAPHY, LIQUID; GHRELIN; HISTAMINE; IODINE RADIOISOTOPES; ISOMERISM; ISOTOPE LABELING; LACTOPEROXIDASE; MICE; PEPTIDES; REPRODUCIBILITY OF RESULTS; RESEARCH DESIGN; SPECTROPHOTOMETRY, ULTRAVIOLET; TANDEM MASS SPECTROMETRY; TECHNOLOGY, PHARMACEUTICAL; TOSYL COMPOUNDS; TYROSINE;

EID: 36749010124     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2007.10.005     Document Type: Article

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