In vitro metabolic stability of obestatin: Kinetics and identification of cleavage products

Peptides

Volumn 29, Issue 10, 2008, Pages 1740-1748

  Vergote, Valentijn ^a   Van Dorpe, Sylvia ^a   Peremans, Kathelijne ^a   Burvenich, Christian ^a   De Spiegeleer, Bart ^a  

^a GHENT UNIVERSITY   (Belgium)

Author keywords

Cleavage sites; ESI ion trap MS MS; Fluorescence; HPLC PDA; In vitro degradation of peptides; Obestatin metabolites; Peptide catabolism; Peptidomimetics; Protease inhibitors; Proteolytic activity

Indexed keywords

DRUG METABOLITE; OBESTATIN;

AMINO TERMINAL SEQUENCE; ANIMAL TISSUE; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DEGRADATION; DRUG HALF LIFE; DRUG METABOLISM; ELECTROSPRAY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HORMONE METABOLISM; IN VITRO STUDY; ION TRAP MASS SPECTROMETRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN HYDROLYSIS;

AMINO ACID SEQUENCE; ANIMALS; FEMALE; HUMANS; KIDNEY; LIVER; MICE; MOLECULAR SEQUENCE DATA; PEPTIDE HORMONES; PEPTIDES; RATS; STOMACH;

EID: 52049107373     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2008.05.018     Document Type: Article

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