Stereodivergent synthesis of 17-α and 17-β-aryl steroids: Application and biological evaluation of D-ring cortistatin analogues

Angewandte Chemie - International Edition

Volumn 48, Issue 24, 2009, Pages 4328-4331

  Shi, Jun ^a   Shigehisa, Hiroki ^a   Guerrero, Carlos A ^a   Shenvi, Ryan A ^a   Li, Chuang Chuang ^a   Baran, Phil S ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Angiogenesis; Asymmetric synthesis; Natural products

Indexed keywords

ANGIOGENESIS; ASYMMETRIC SYNTHESIS; BIOLOGICAL EVALUATION; CORTISTATIN A; NATURAL PRODUCTS; REDUCTION PROCESS; STEREOCENTERS; STEREODIVERGENT SYNTHESIS; SYNTHESIS FEATURES;

LIPIDS;

ELECTRON TRANSITIONS;

ANGIOGENESIS INHIBITOR; CORTISTATIN A; ISOQUINOLINE DERIVATIVE; POLYCYCLIC HYDROCARBON; STEROID;

CELL LINE; CHEMISTRY; HUMAN; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANGIOGENESIS INHIBITORS; CELL LINE; HUMANS; ISOQUINOLINES; POLYCYCLIC COMPOUNDS; STEREOISOMERISM; STEROIDS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 70349784889     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200901116     Document Type: Article

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