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e) The syntheses of ketones 1 and 2 were the first examples of practical proline-catalyzed asymmetric reactions and were seminal achievements in the field of organocatalysis.
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f) Cortistatins can also be considered B(9a)-homo-19-norpregnanes or abeo-pregnanes: http://www.chem.qmul.ac.uk/iupac/steroid/3S07.html.
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The rotations are indeed very different but were measured in different solvents. The other spectroscopic data agree within experimental error
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b) The rotations are indeed very different but were measured in different solvents. The other spectroscopic data agree within experimental error.
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34548528924
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