P2Y5 is a Gαi, Gα12/13 G protein-coupled receptor activated by lysophosphatidic acid that reduces intestinal cell adhesion

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 297, Issue 4, 2009, Pages

  Lee, Mike ^a   Choi, Sungwon ^a   Halldén, Gunnel ^a   Yo, Sek Jin ^a   Schichnes, Denise ^a   Aponte, Gregory W ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Farnesyl pyrophosphate; GPCR; Mucosa; Rho; Serum response element

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; FARNESYL DIPHOSPHATE; G PROTEIN COUPLED RECEPTOR; LYSOPHOSPHATIDIC ACID; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; P2Y5 RECEPTOR; PERTUSSIS TOXIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG; ADRBK1 PROTEIN, RAT; ENZYME INHIBITOR; G PROTEIN COUPLED RECEPTOR KINASE 2; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; GUANINE NUCLEOTIDE EXCHANGE FACTOR; HYBRID PROTEIN; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; ISOPRENOID PHOSPHATE; LYSOPHOSPHOLIPID; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; PURINERGIC P2 RECEPTOR; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR; RHO KINASE; SESQUITERPENE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CELL ACTIVATION; CELL ADHESION; GENETIC TRANSCRIPTION; HETEROLOGOUS EXPRESSION; INTESTINE CELL; INTESTINE MUCOSA; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; RAT; SERUM RESPONSIVE ELEMENT; SMALL INTESTINE; ANIMAL; ANTAGONISTS AND INHIBITORS; CALCIUM SIGNALING; CHO CELL LINE; CRICETULUS; DOWN REGULATION; DRUG EFFECTS; EPITHELIUM CELL; GENETIC TRANSFECTION; GENETICS; HAMSTER; HELA CELL LINE; HUMAN; METABOLISM; PHOSPHORYLATION; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

ANIMALS; CALCIUM SIGNALING; CELL ADHESION; CHO CELLS; CRICETINAE; CRICETULUS; DOWN-REGULATION; ENZYME INHIBITORS; EPITHELIAL CELLS; G-PROTEIN-COUPLED RECEPTOR KINASE 2; GTP-BINDING PROTEIN ALPHA SUBUNITS, G12-G13; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HELA CELLS; HUMANS; INTESTINAL MUCOSA; LYSOPHOSPHOLIPIDS; MALE; MAP KINASE KINASE 1; MAP KINASE KINASE 2; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PHOSPHORYLATION; POLYISOPRENYL PHOSPHATES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR CROSS-TALK; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTORS, PURINERGIC P2; RECOMBINANT FUSION PROTEINS; RHO GTP-BINDING PROTEINS; RHO-ASSOCIATED KINASES; RNA, MESSENGER; SERUM RESPONSE ELEMENT; SESQUITERPENES; TRANSFECTION; RHO GUANINE NUCLEOTIDE EXCHANGE FACTORS;

EID: 70349756906     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00191.2009     Document Type: Article

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