Sevoflurane and propofol depolarize mitochondria in rat and human cerebrocortical synaptosomes by different mechanisms

Acta Anaesthesiologica Scandinavica

Volumn 53, Issue 10, 2009, Pages 1354-1360

  Bains, R ^a   Moe, M C ^a   Vinje, M L ^a   Berg Johnsen, J ^a  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; FLUORESCENT DYE; FURA 2; PROPOFOL; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; SEVOFLURANE;

ANIMAL EXPERIMENT; ARTICLE; BRAIN CORTEX; BRAIN SYNAPTOSOME; CALCIUM CELL LEVEL; CONTROLLED STUDY; DOSE RESPONSE; DRUG INHIBITION; DRUG MECHANISM; ELECTRON TRANSPORT; FEMALE; HUMAN; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; RAT; RESPIRATORY CHAIN;

ADENOSINE TRIPHOSPHATASES; ANESTHETICS, INHALATION; ANESTHETICS, INTRAVENOUS; ANIMALS; CALCIUM; CARRIER PROTEINS; ELECTRON TRANSPORT; FEMALE; HUMANS; MEMBRANE PROTEINS; METHYL ETHERS; MITOCHONDRIA; NEURONS; PROPOFOL; RANDOM ALLOCATION; RATS; RATS, WISTAR; SYNAPTOSOMES; TREATMENT OUTCOME;

EID: 70349734683     PISSN: 00015172     EISSN: 13996576     Source Type: Journal    
DOI: 10.1111/j.1399-6576.2009.02047.x     Document Type: Article

References (37)

1. Engelhard K, Werner C. Inhalational or intravenous anesthetics for craniotomies? Pro inhalational. Curr Opin Anaesthesiol 2006 19 : 504 508.
2. Petersen KD, Landsfeldt U, Cold GE, Petersen CB, Mau S, Hauerberg J, Holst P, Olsen KS. Intracranial pressure and cerebral hemodynamic in patients with cerebral tumors: a randomized prospective study of patients subjected to craniotomy in propofol-fentanyl, isoflurane-fentanyl, or sevoflurane-fentanyl anesthesia. Anesthesiology 2003 98 : 329 336.
3. Hans P, Bonhomme V. Why we still use intravenous drugs as the basic regimen for neurosurgical anaesthesia. Curr Opin Anaesthesiol 2006 19 : 498 503.
4. Mattson MP, Kroemer G. Mitochondria in cell death: novel targets for neuroprotection and cardioprotection. Trends Mol Med 2003 9 : 196 205.
5. Nicholls DG, Budd SL. Mitochondria and neuronal survival. Physiol Rev 2000 80 : 315 360.
6. Boveris A, Oshino N, Chance B. The cellular production of hydrogen peroxide. Biochem J 1972 128 : 617 630.
7. van Belzen R, Kotlyar AB, Moon N, Dunham WR, Albracht SP. The iron-sulfur clusters 2 and ubisemiquinone radicals of NADH: ubiquinone oxidoreductase are involved in energy coupling in submitochondrial particles. Biochemistry 1997 36 : 886 893.
8. Duchen MR. Mitochondria and calcium: from cell signalling to cell death. J Physiol 2000 529 : 57 68.
9. Tanaka K, Weihrauch D, Kehl F, Ludwig LM, LaDisa JF Jr, Kersten JR, Pagel PS, Warltier DC. Mechanism of preconditioning by isoflurane in rabbits: a direct role for reactive oxygen species. Anesthesiology 2002 97 (Part 1) : 1485 1490.
10. Müllenheim J, Ebel D, Frässdorf J, Preckel B, Thämer V, Schlack W. Isoflurane preconditions myocardium against infarction via release of free radicals. Anesthesiology 2002 96 : 934 940.
11. Ludwig LM, Tanaka K, Eells JT, Weihrauch D, Pagel PS, Kersten JR, Warltier DC. Preconditioning by isoflurane is mediated by reactive oxygen species generated from mitochondrial electron transport chain complex III. Anesth Analg 2004 99 : 1308 1315 table of contents.
12. Bains R, Moe MC, Larsen GA, Berg-Johnsen J, Vinje ML. Volatile anaesthetics depolarize neural mitochondria by inhibiton of the electron transport chain. Acta Anaesthesiol Scand 2006 50 : 572 579.
13. Larsen M, Haugstad TS, Berg-Johnsen J, Langmoen IA. Effect of isoflurane on release and uptake of gamma-aminobutyric acid from rat cortical synaptosomes. Br J Anaesth 1998 80 : 634 638.
14. 2+) during stimulated release of endogenous glutamate from human cerebrocortical synaptosomes. Brain Res 1999 843 : 199 201.
15. Franks NP, Lieb WR. Temperature dependence of the potency of volatile general anesthetics: implications for in vitro experiments. Anesthesiology 1996 84 : 716 720.
16. 2+ indicators with greatly improved fluorescence properties. J Biol Chem 1985 260 : 3440 3450.
17. Cossarizza A, Baccarani-Contri M, Kalashnikova G, Franceschi C. A new method for the cytofluorimetric analysis of mitochondrial membrane potential using the J-aggregate forming lipophilic cation 5,5′,6,6′- tetrachloro-1,1′,3,3′-tetraethylbenzimidazolcarbocyanine iodide (JC-1). Biochem Biophys Res Commun 1993 197 : 40 5.
18. Nicholls DG. Bioenergetics and transmitter release in the isolated nerve terminal. Neurochem Res 2003 28 : 1433 1441.
19. Nicholls DG. Presynaptic modulation of glutamate release. Prog Brain Res 1998 116 : 15 22.
20. Gunter KK, Gunter TE. Transport of calcium by mitochondria. J Bioenerg Biomembr 1994 26 : 471 485.
21. Ward MW, Rego AC, Frenguelli BG, Nicholls DG. Mitochondrial membrane potential and glutamate excitotoxicity in cultured cerebellar granule cells. J Neurosci 2000 20 : 7208 7219.
22. Nicholls DG, Ward MW. Mitochondrial membrane potential and neuronal glutamate excitotoxicity: mortality and millivolts. Trends Neurosci 2000 23 : 166 174.
23. Berridge MJ, Bootman MD, Roderick HL. Calcium signalling: dynamics, homeostasis and remodelling. Nat Rev Mol Cell Biol 2003 4 : 517 529.
24. LaFrance R, Brustovetsky N, Sherburne C, Delong D, Dubinsky JM. Age-related changes in regional brain mitochondria from Fischer 344 rats. Aging Cell 2005 4 : 139 145.
25. Moe MC, Bains R, Vinje ML, Larsen GA, Kampenhaug EB, Berg-Johnsen J. Sevoflurane depolarizes pre-synaptic mitochondria in the central nervous system. Acta Anaesthesiol Scand 2004 48 : 562 568.
26. Artru AA, Lam AM, Johnson JO, Sperry RJ. Intracranial pressure, middle cerebral artery flow velocity, and plasma inorganic fluoride concentrations in neurosurgical patients receiving sevoflurane or isoflurane. Anesth Analg 1997 85 : 587 592.
27. Summors AC, Gupta AK, Matta BF. Dynamic cerebral autoregulation during sevoflurane anesthesia: a comparison with isoflurane. Anesth Analg 1999 88 : 341 345.
28. Adembri C, Venturi L, Pellegrini-Giampietro DE. Neuroprotective effects of propofol in acute cerebral injury. CNS Drug Rev 2007 13 : 333 351.
29. Wu GJ, Tai YT, Chen TL, Lin LL, Ueng YF, Chen RM. Propofol specifically inhibits mitochondrial membrane potential but not complex I NADH dehydrogenase activity, thus reducing cellular ATP biosynthesis and migration of macrophages. Ann NY Acad Sci 2005 1042 : 168 176.
30. Sanders RD, Ma D, Maze M. Anaesthesia induced neuroprotection. Best Pract Res Clin Anaesthesiol 2005 19 : 461 474.
31. Berg-Johnsen J, Langmoen IA. The effect of isoflurane on excitatory synaptic transmission in the rat hippocampus. Acta Anaesthesiol Scand 1992 36 : 350 355.
32. Vinje ML, Moe MC, Valo ET, Berg-Johnsen J. The effect of sevoflurane on glutamate release and uptake in rat cerebrocortical presynaptic terminals. Acta Anaesthesiol Scand 2002 46 : 103 108.
33. Franks NP, Lieb WR. Which molecular targets are most relevant to general anaesthesia? Toxicol Lett 1998 100-101 : 1 8.
34. Kehl F, Payne RS, Roewer N, Schurr A. Sevoflurane-induced preconditioning of rat brain in vitro and the role of K(ATP) channels. Brain Res 2004 1021 : 76 81.
35. Xiong L, Zheng Y, Wu M, Hou L, Zhu Z, Zhang X, Lu Z. Preconditioning with isoflurane produces dose-dependent neuroprotection via activation of adenosine triphosphate-regulated potassium channels after focal cerebral ischemia in rats. Anesth Analg 2003 96 : 233 237, table of contents.
36. (ATP) channels: reduction of myocardial infarct size with an acute memory phase. Anesthesiology 1997 87 : 361 370.
37. Dzeja PP, Holmuhamedov EL, Ozcan C, Pucar D, Jahangir A, Terzic A. Mitochondria: gateway for cytoprotection. Circ Res 2001 89 : 744 746.