메뉴 건너뛰기




Volumn 7, Issue 4, 2009, Pages 506-512

Regulation of the sodium-phosphate cotransporter Pit-1 and its role in vascular calcification

Author keywords

Atherosclerosis; Bone morphogenetic proteins; Chronic kidney disease; Diabetes; Hyperphospatemia; Phosphate transport; Vascular calcification

Indexed keywords

ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN 2; EPLERENONE; INTERLEUKIN 6; MESSENGER RNA; MINERALOCORTICOID RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; OSTEOCALCIN; OSTEOPONTIN; OSTEOPROTEGERIN; PHOSPHATE; PHOSPHATE INORGANIC TRANSPORTER 1; PHOSPHATE INORGANIC TRANSPORTER 2; PHOSPHATIDYLINOSITOL 3 KINASE; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; PROTEIN KINASE B; PROTEIN KINASE C; SODIUM; SODIUM PHOSPHATE COTRANSPORTER; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; SPIRONOLACTONE; TRANSCRIPTION FACTOR MSX2; TRANSCRIPTION FACTOR RUNX2; TRANSCRIPTION FACTOR SOX9; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; UNINDEXED DRUG; WNT PROTEIN;

EID: 70349678663     PISSN: 15701611     EISSN: None     Source Type: Journal    
DOI: 10.2174/157016109789043946     Document Type: Review
Times cited : (11)

References (102)
  • 2
    • 33947111420 scopus 로고    scopus 로고
    • Phosphate transport: Molecular basis, regulation and pathophysiology
    • Tenenhouse HS. Phosphate transport: molecular basis, regulation and pathophysiology. J Steroid Biochem Mol Biol 2007; 103: 572-7.
    • (2007) J Steroid Biochem Mol Biol , vol.103 , pp. 572-577
    • Tenenhouse, H.S.1
  • 4
    • 33750203846 scopus 로고    scopus 로고
    • Proximal tubular handling of phosphate: A molecular perspective
    • Forster IC, Hernando N, Biber J, Murer H. Proximal tubular handling of phosphate: A molecular perspective. Kidney Int 2006; 70: 1548-59.
    • (2006) Kidney Int , vol.70 , pp. 1548-1559
    • Forster, I.C.1    Hernando, N.2    Biber, J.3    Murer, H.4
  • 6
    • 33646157733 scopus 로고    scopus 로고
    • Role of the sodium-dependent phosphate cotransporter, Pit-1, in vascular smooth muscle cell calcification
    • Li X, Yang HY, Giachelli CM. Role of the sodium-dependent phosphate cotransporter, Pit-1, in vascular smooth muscle cell calcification. Circ Res 2006; 98: 905-12.
    • (2006) Circ Res , vol.98 , pp. 905-912
    • Li, X.1    Yang, H.Y.2    Giachelli, C.M.3
  • 7
    • 0025400304 scopus 로고
    • Characterization of a human gene conferring sensitivity to infection by gibbon ape leukemia virus
    • O'Hara B, Johann SV, Klinger HP, Blair DG, Rubinson H, Dunn KJ, et al. Characterization of a human gene conferring sensitivity to infection by gibbon ape leukemia virus. Cell Growth Differ 1990; 1: 119-27.
    • (1990) Cell Growth Differ , vol.1 , pp. 119-127
    • O'Hara, B.1    Johann, S.V.2    Klinger, H.P.3    Blair, D.G.4    Rubinson, H.5    Dunn, K.J.6
  • 8
    • 0028341123 scopus 로고
    • Cell-surface receptors for gibbon ape leukemia virus and amphotropic murine retrovirus are inducible sodium-dependent phosphate symporters
    • Kavanaugh MP, Miller DG, Zhang W, Law W, Kozak SL, Kabat D, et al. Cell-surface receptors for gibbon ape leukemia virus and amphotropic murine retrovirus are inducible sodium-dependent phosphate symporters. Proc Natl Acad Sci USA 1994; 91: 7071-5.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 7071-7075
    • Kavanaugh, M.P.1    Miller, D.G.2    Zhang, W.3    Law, W.4    Kozak, S.L.5    Kabat, D.6
  • 9
    • 0028090524 scopus 로고
    • The cellular receptor for gibbon ape leukemia virus is a novel high affinity sodium-dependent phosphate transporter
    • Olah Z, Lehel C, Anderson WB, Eiden MV, Wilson CA. The cellular receptor for gibbon ape leukemia virus is a novel high affinity sodium-dependent phosphate transporter. J Biol Chem 1994; 269: 25426-31.
    • (1994) J Biol Chem , vol.269 , pp. 25426-25431
    • Olah, Z.1    Lehel, C.2    Anderson, W.B.3    Eiden, M.V.4    Wilson, C.A.5
  • 11
    • 0032889973 scopus 로고    scopus 로고
    • In vivo expression of transcripts encoding the Glvr-1 phosphate transporter/ retrovirus receptor during bone development
    • Palmer G, Zhao J, Bonjour J, Hofstetter W, Caverzasio J. In vivo expression of transcripts encoding the Glvr-1 phosphate transporter/ retrovirus receptor during bone development. Bone 1999; 24: 1-7.
    • (1999) Bone , vol.24 , pp. 1-7
    • Palmer, G.1    Zhao, J.2    Bonjour, J.3    Hofstetter, W.4    Caverzasio, J.5
  • 12
    • 0034456665 scopus 로고    scopus 로고
    • Transforming growth factor-beta stimulates inorganic phosphate transport and expression of the type III phosphate transporter Glvr-1 in chondrogenic ATDC5 cells
    • Palmer G, Guicheux J, Bonjour JP, Caverzasio J. Transforming growth factor-beta stimulates inorganic phosphate transport and expression of the type III phosphate transporter Glvr-1 in chondrogenic ATDC5 cells. Endocrinology 2000; 141: 2236-43.
    • (2000) Endocrinology , vol.141 , pp. 2236-2243
    • Palmer, G.1    Guicheux, J.2    Bonjour, J.P.3    Caverzasio, J.4
  • 13
    • 0035861204 scopus 로고    scopus 로고
    • Species-specific mechanisms control the activity of the Pit1/PIT1 phosphate transporter gene promoter in mouse and human
    • Palmer G, Manen D, Bonjour JP, Caverzasio J. Species-specific mechanisms control the activity of the Pit1/PIT1 phosphate transporter gene promoter in mouse and human. Gene 2001; 279: 49-62.
    • (2001) Gene , vol.279 , pp. 49-62
    • Palmer, G.1    Manen, D.2    Bonjour, J.P.3    Caverzasio, J.4
  • 14
    • 0034748185 scopus 로고    scopus 로고
    • Identification of the type II Na(+)-Pi cotransporter (Npt2) in the osteoclast and the skeletal phenotype of Npt2-/-mice
    • Gupta A, Tenenhouse HS, Hoag HM, Wang D, Khadeer MA, Namba N, et al. Identification of the type II Na(+)-Pi cotransporter (Npt2) in the osteoclast and the skeletal phenotype of Npt2-/-mice. Bone 2001; 29: 467-76.
    • (2001) Bone , vol.29 , pp. 467-476
    • Gupta, A.1    Tenenhouse, H.S.2    Hoag, H.M.3    Wang, D.4    Khadeer, M.A.5    Namba, N.6
  • 15
    • 33645281416 scopus 로고    scopus 로고
    • Up-regulation of Cbfa1 and Pit-1 in calcified artery of uraemic rats with severe hyperphosphataemia and secondary hyperparathyroidism
    • Mizobuchi M, Ogata H, Hatamura I, et al. Up-regulation of Cbfa1 and Pit-1 in calcified artery of uraemic rats with severe hyperphosphataemia and secondary hyperparathyroidism. Nephrol Dial Transplant 2006; 21: 911-6.
    • (2006) Nephrol Dial Transplant , vol.21 , pp. 911-916
    • Mizobuchi, M.1    Ogata, H.2    Hatamura, I.3
  • 16
    • 0032484615 scopus 로고    scopus 로고
    • Immunodetection of a type III sodium-dependent phosphate cotransporter in tissues and OK cells
    • Boyer CJ, Baines AD, Beaulieu E, Beliveau R. Immunodetection of a type III sodium-dependent phosphate cotransporter in tissues and OK cells. Biochim Biophys Acta 1998; 1368: 73-83.
    • (1998) Biochim Biophys Acta , vol.1368 , pp. 73-83
    • Boyer, C.J.1    Baines, A.D.2    Beaulieu, E.3    Beliveau, R.4
  • 17
    • 15244351326 scopus 로고    scopus 로고
    • Identification and localization of sodium-phosphate cotransporters in hepatocytes and cholangiocytes of rat liver
    • Frei P, Gao B, Hagenbuch B, et al. Identification and localization of sodium-phosphate cotransporters in hepatocytes and cholangiocytes of rat liver. Am J Physiol Gastrointest Liver Physiol 2005; 288: G771-8.
    • (2005) Am J Physiol Gastrointest Liver Physiol , vol.288
    • Frei, P.1    Gao, B.2    Hagenbuch, B.3
  • 18
    • 0029128628 scopus 로고
    • Retrovirus receptors
    • Weiss RA, Tailor CS. Retrovirus receptors. Cell 1995; 82: 531-33.
    • (1995) Cell , vol.82 , pp. 531-533
    • Weiss, R.A.1    Tailor, C.S.2
  • 19
    • 0036310359 scopus 로고    scopus 로고
    • Reassessing the role of region A in Pit1-mediated viral entry
    • Farrell KB, Russ JL, Murthy RK, Eiden MV. Reassessing the role of region A in Pit1-mediated viral entry. J Virol 2002; 76: 7683-93.
    • (2002) J Virol , vol.76 , pp. 7683-7693
    • Farrell, K.B.1    Russ, J.L.2    Murthy, R.K.3    Eiden, M.V.4
  • 20
    • 0026533746 scopus 로고
    • GLVR1, a receptor for gibbon ape leukemia virus, is homologous to a phosphate permease of Neurospora crassa and is expressed at high levels in the brain and thymus
    • Johann SV, Gibbons JJ, O'Hara B. GLVR1, a receptor for gibbon ape leukemia virus, is homologous to a phosphate permease of Neurospora crassa and is expressed at high levels in the brain and thymus. J Virol 1992; 66: 1635-40.
    • (1992) J Virol , vol.66 , pp. 1635-1640
    • Johann, S.V.1    Gibbons, J.J.2    O'Hara, B.3
  • 21
    • 0033695539 scopus 로고    scopus 로고
    • Cloning and characterization of a type III Na-dependent phosphate cotransporter from mouse intestine
    • Bai L, Collins JF, Ghishan FK. Cloning and characterization of a type III Na-dependent phosphate cotransporter from mouse intestine. Am J Physiol Cell Physiol 2000; 279: C1135-43.
    • (2000) Am J Physiol Cell Physiol , vol.279
    • Bai, L.1    Collins, J.F.2    Ghishan, F.K.3
  • 22
    • 0035024651 scopus 로고    scopus 로고
    • Transmembrane topology of PiT-2, a phosphate transporter-retrovirus receptor
    • Salaun C, Rodrigues P, Heard JM. Transmembrane topology of PiT-2, a phosphate transporter-retrovirus receptor. J Virol 2001; 75: 5584-92.
    • (2001) J Virol , vol.75 , pp. 5584-5592
    • Salaun, C.1    Rodrigues, P.2    Heard, J.M.3
  • 23
    • 0032947280 scopus 로고    scopus 로고
    • Modulation of phosphate uptake and amphotropic murine leukemia virus entry by posttranslational modifications of PIT-2
    • Rodrigues P, Heard JM. Modulation of phosphate uptake and amphotropic murine leukemia virus entry by posttranslational modifications of PIT-2. J Virol 1999; 73: 3789-99.
    • (1999) J Virol , vol.73 , pp. 3789-3799
    • Rodrigues, P.1    Heard, J.M.2
  • 24
    • 0033982505 scopus 로고    scopus 로고
    • Stimulation of sodium-dependent phosphate transport and signaling mechanisms induced by basic fibroblast growth factor in MC3T3-E1 osteoblast-like cells
    • Suzuki A, Palmer G, Bonjour JP, Caverzasio J. Stimulation of sodium-dependent phosphate transport and signaling mechanisms induced by basic fibroblast growth factor in MC3T3-E1 osteoblast-like cells. J Bone Miner Res 2000; 15: 95-102.
    • (2000) J Bone Miner Res , vol.15 , pp. 95-102
    • Suzuki, A.1    Palmer, G.2    Bonjour, J.P.3    Caverzasio, J.4
  • 25
    • 0031038098 scopus 로고    scopus 로고
    • Platelet-derived growth factor stimulates sodium-dependent Pi transport in osteoblastic cells via phospholipase Cgamma and phosphatidylinositol 3′ -kinase
    • Zhen X, Bonjour JP, Caverzasio J. Platelet-derived growth factor stimulates sodium-dependent Pi transport in osteoblastic cells via phospholipase Cgamma and phosphatidylinositol 3′ -kinase. J Bone Miner Res 1997; 12: 36-44.
    • (1997) J Bone Miner Res , vol.12 , pp. 36-44
    • Zhen, X.1    Bonjour, J.P.2    Caverzasio, J.3
  • 26
    • 0043112457 scopus 로고    scopus 로고
    • Two highly conserved glutamate residues critical for type III sodium-dependent phosphate transport revealed by uncoupling transport function from retroviral receptor function
    • Bottger P, Pedersen L. Two highly conserved glutamate residues critical for type III sodium-dependent phosphate transport revealed by uncoupling transport function from retroviral receptor function. J Biol Chem 2002; 277: 42741-7.
    • (2002) J Biol Chem , vol.277 , pp. 42741-42747
    • Bottger, P.1    Pedersen, L.2
  • 27
    • 34547735935 scopus 로고    scopus 로고
    • Deciphering PiT transport kinetics and substrate specificity using electrophysiology and flux measurements
    • Ravera S, Virkki LV, Murer H, Forster IC. Deciphering PiT transport kinetics and substrate specificity using electrophysiology and flux measurements. Am J Physiol Cell Physiol 2007; 293: C606-20.
    • (2007) Am J Physiol Cell Physiol , vol.293
    • Ravera, S.1    Virkki, L.V.2    Murer, H.3    Forster, I.C.4
  • 28
    • 34247339631 scopus 로고    scopus 로고
    • Characterization of phosphate transport in rat vascular smooth muscle cells: Implications for vascular calcification
    • Villa-Bellosta R, Bogaert YE, Levi M, Sorribas V. Characterization of phosphate transport in rat vascular smooth muscle cells: implications for vascular calcification. Arterioscler Thromb Vasc Biol 2007; 27: 1030-6.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 1030-1036
    • Villa-Bellosta, R.1    Bogaert, Y.E.2    Levi, M.3    Sorribas, V.4
  • 29
    • 34250760779 scopus 로고    scopus 로고
    • Characterisation of inorganic phosphate transport in bovine articular chondrocytes
    • Solomon DH, Wilkins RJ, Meredith D, Browning JA. Characterisation of inorganic phosphate transport in bovine articular chondrocytes. Cell Physiol Biochem 2007; 20: 99-108.
    • (2007) Cell Physiol Biochem , vol.20 , pp. 99-108
    • Solomon, D.H.1    Wilkins, R.J.2    Meredith, D.3    Browning, J.A.4
  • 30
    • 0034080244 scopus 로고    scopus 로고
    • A novel in vitro culture system for analysis of functional role of phosphate transport in endochondral ossification
    • Guicheux J, Palmer G, Shukunami C, Hiraki Y, Bonjour JP, Caverzasio J. A novel in vitro culture system for analysis of functional role of phosphate transport in endochondral ossification. Bone 2000; 27: 69-74.
    • (2000) Bone , vol.27 , pp. 69-74
    • Guicheux, J.1    Palmer, G.2    Shukunami, C.3    Hiraki, Y.4    Bonjour, J.P.5    Caverzasio, J.6
  • 31
    • 51549109697 scopus 로고    scopus 로고
    • Role of rat sodium/phosphate cotransporters in the cell membrane transport of arsenate
    • Villa-Bellosta R, Sorribas V. Role of rat sodium/phosphate cotransporters in the cell membrane transport of arsenate. Toxicol Appl Pharmacol 2008, 232(1): 125-34.
    • (2008) Toxicol Appl Pharmacol , vol.232 , Issue.1 , pp. 125-134
    • Villa-Bellosta, R.1    Sorribas, V.2
  • 32
    • 0031980091 scopus 로고    scopus 로고
    • Na+ -phosphate cotransport in mouse distal convoluted tubule cells: Evidence for Glvr-1 and Ram-1 gene expression
    • Tenenhouse HS, Gauthier C, Martel J, Gesek FA, Coutermarsh BA, Friedman PA. Na+ -phosphate cotransport in mouse distal convoluted tubule cells: evidence for Glvr-1 and Ram-1 gene expression. J Bone Miner Res 1998; 13: 590-7.
    • (1998) J Bone Miner Res , vol.13 , pp. 590-597
    • Tenenhouse, H.S.1    Gauthier, C.2    Martel, J.3    Gesek, F.A.4    Coutermarsh, B.A.5    Friedman, P.A.6
  • 33
    • 1942486773 scopus 로고    scopus 로고
    • Osteogenic regulation of vascular calcification: An early perspective
    • Vattikuti R, Towler DA. Osteogenic regulation of vascular calcification: an early perspective. Am J Physiol Endocrinol Metab 2004; 286: E686-96.
    • (2004) Am J Physiol Endocrinol Metab , vol.286
    • Vattikuti, R.1    Towler, D.A.2
  • 34
    • 44649133999 scopus 로고    scopus 로고
    • Vascular calcification: Pathobiology of a multifaceted disease
    • Demer LL, Tintut Y. Vascular calcification: pathobiology of a multifaceted disease. Circulation 2008; 117: 2938-48.
    • (2008) Circulation , vol.117 , pp. 2938-2948
    • Demer, L.L.1    Tintut, Y.2
  • 35
    • 22744434737 scopus 로고    scopus 로고
    • Bone morphogenetic proteins in vascular calcification
    • Hruska KA, Mathew S, Saab G. Bone morphogenetic proteins in vascular calcification. Circ Res 2005; 97: 105-14.
    • (2005) Circ Res , vol.97 , pp. 105-114
    • Hruska, K.A.1    Mathew, S.2    Saab, G.3
  • 36
    • 0033835868 scopus 로고    scopus 로고
    • Cellular interactions and signaling in cartilage development
    • DeLise AM, Fischer L, Tuan RS. Cellular interactions and signaling in cartilage development. Osteoarthritis Cartilage 2000; 8: 309-34.
    • (2000) Osteoarthritis Cartilage , vol.8 , pp. 309-334
    • DeLise, A.M.1    Fischer, L.2    Tuan, R.S.3
  • 37
    • 18244392685 scopus 로고    scopus 로고
    • Unique coexpression in osteoblasts of broadly expressed genes accounts for the spatial restriction of ECM mineralization to bone
    • Murshed M, Harmey D, Millan JL, McKee MD, Karsenty G. Unique coexpression in osteoblasts of broadly expressed genes accounts for the spatial restriction of ECM mineralization to bone. Genes Dev 2005; 19: 1093-104.
    • (2005) Genes Dev , vol.19 , pp. 1093-1104
    • Murshed, M.1    Harmey, D.2    Millan, J.L.3    McKee, M.D.4    Karsenty, G.5
  • 39
    • 0017282062 scopus 로고
    • Calcification of matrix vesicles in human aortic valve and aortic media
    • Kim KM. Calcification of matrix vesicles in human aortic valve and aortic media. Fed Proc 1976; 35: 156-62.
    • (1976) Fed Proc , vol.35 , pp. 156-162
    • Kim, K.M.1
  • 40
    • 14544283020 scopus 로고    scopus 로고
    • Human vascular smooth muscle cells undergo vesicle-mediated calcification in response to changes in extracellular calcium and phosphate concentrations: A potential mechanism for accelerated vascular calcification in ESRD
    • Reynolds JL, Joannides AJ, Skepper JN, McNair R, Schurgers LJ, Proudfoot D, et al. Human vascular smooth muscle cells undergo vesicle-mediated calcification in response to changes in extracellular calcium and phosphate concentrations: a potential mechanism for accelerated vascular calcification in ESRD. J Am Soc Nephrol 2004; 15: 2857-67.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 2857-2867
    • Reynolds, J.L.1    Joannides, A.J.2    Skepper, J.N.3    McNair, R.4    Schurgers, L.J.5    Proudfoot, D.6
  • 41
    • 0025925331 scopus 로고
    • Characterization of a Pi transport system in cartilage matrix vesicles. Potential role in the calcification process
    • Montessuit C, Caverzasio J, Bonjour JP. Characterization of a Pi transport system in cartilage matrix vesicles. Potential role in the calcification process. J Biol Chem 1991; 266: 17791-7.
    • (1991) J Biol Chem , vol.266 , pp. 17791-17797
    • Montessuit, C.1    Caverzasio, J.2    Bonjour, J.P.3
  • 42
    • 0029999082 scopus 로고    scopus 로고
    • Characteristics and regulation of Pi transport in osteogenic cells for bone metabolism
    • Caverzasio J, Bonjour JP. Characteristics and regulation of Pi transport in osteogenic cells for bone metabolism. Kidney Int 1996; 49: 975-80.
    • (1996) Kidney Int , vol.49 , pp. 975-980
    • Caverzasio, J.1    Bonjour, J.P.2
  • 44
    • 33751417865 scopus 로고    scopus 로고
    • High glucose increases the expression of Cbfa1 and BMP-2 and enhances the calcification of vascular smooth muscle cells
    • Chen NX, Duan D, O'Neill KD, Moe SM. High glucose increases the expression of Cbfa1 and BMP-2 and enhances the calcification of vascular smooth muscle cells. Nephrol Dial Transplant 2006; 21: 3435-42.
    • (2006) Nephrol Dial Transplant , vol.21 , pp. 3435-3442
    • Chen, N.X.1    Duan, D.2    O'Neill, K.D.3    Moe, S.M.4
  • 45
    • 0018065914 scopus 로고
    • Role of phosphate and pyrophosphate in soft tissue calcification
    • Alfrey AC, Ibels LS. Role of phosphate and pyrophosphate in soft tissue calcification. Adv Exp Med Biol 1978; 103: 187-93.
    • (1978) Adv Exp Med Biol , vol.103 , pp. 187-193
    • Alfrey, A.C.1    Ibels, L.S.2
  • 46
    • 0031920748 scopus 로고    scopus 로고
    • Association of serum phosphorus and calcium x phosphate product with mortality risk in chronic hemodialysis patients: A national study
    • Block GA, Hulbert-Shearon TE, Levin NW, Port FK. Association of serum phosphorus and calcium x phosphate product with mortality risk in chronic hemodialysis patients: a national study. Am J Kidney Dis 1998; 31: 607-17.
    • (1998) Am J Kidney Dis , vol.31 , pp. 607-617
    • Block, G.A.1    Hulbert-Shearon, T.E.2    Levin, N.W.3    Port, F.K.4
  • 48
    • 9644298257 scopus 로고    scopus 로고
    • Elevated extracellular calcium levels induce smooth muscle cell matrix mineralization in vitro
    • Yang H, Curinga G, Giachelli CM. Elevated extracellular calcium levels induce smooth muscle cell matrix mineralization in vitro. Kidney Int 2004; 66: 2293-9.
    • (2004) Kidney Int , vol.66 , pp. 2293-2299
    • Yang, H.1    Curinga, G.2    Giachelli, C.M.3
  • 49
    • 34250197188 scopus 로고    scopus 로고
    • Osteoblast autonomous Pi regulation via Pit1 plays a role in bone mineralization
    • Yoshiko Y, Candeliere GA, Maeda N, Aubin JE. Osteoblast autonomous Pi regulation via Pit1 plays a role in bone mineralization. Mol Cell Biol 2007; 27: 4465-74.
    • (2007) Mol Cell Biol , vol.27 , pp. 4465-4474
    • Yoshiko, Y.1    Candeliere, G.A.2    Maeda, N.3    Aubin, J.E.4
  • 50
    • 3042844136 scopus 로고    scopus 로고
    • Regulation of phosphate (Pi) transport and NaPi-III transporter (Pit-1) mRNA in rat osteoblasts
    • Zoidis E, Ghirlanda-Keller C, Gosteli-Peter M, Zapf J, Schmid C. Regulation of phosphate (Pi) transport and NaPi-III transporter (Pit-1) mRNA in rat osteoblasts. J Endocrinol 2004; 181: 531-40.
    • (2004) J Endocrinol , vol.181 , pp. 531-540
    • Zoidis, E.1    Ghirlanda-Keller, C.2    Gosteli-Peter, M.3    Zapf, J.4    Schmid, C.5
  • 51
    • 7844250506 scopus 로고    scopus 로고
    • Molecular cloning and hormonal regulation of PiT-1, a sodium-dependent phosphate cotransporter from rat parathyroid glands
    • Tatsumi S, Segawa H, Morita K, Haga H, Kouda T, Yamamoto H, et al. Molecular cloning and hormonal regulation of PiT-1, a sodium-dependent phosphate cotransporter from rat parathyroid glands. Endocrinology 1998; 139: 1692-9.
    • (1998) Endocrinology , vol.139 , pp. 1692-1699
    • Tatsumi, S.1    Segawa, H.2    Morita, K.3    Haga, H.4    Kouda, T.5    Yamamoto, H.6
  • 52
    • 0035823493 scopus 로고    scopus 로고
    • Alterations in the sensing and transport of phosphate and calcium by differentiating chondrocytes
    • Wang D, Canaff L, Davidson D, Corluka A, Liu H, Hendy GN, et al. Alterations in the sensing and transport of phosphate and calcium by differentiating chondrocytes. J Biol Chem 2001; 276: 33995-4005.
    • (2001) J Biol Chem , vol.276 , pp. 33995-34005
    • Wang, D.1    Canaff, L.2    Davidson, D.3    Corluka, A.4    Liu, H.5    Hendy, G.N.6
  • 53
    • 0028180137 scopus 로고
    • TGF-beta 1 and 25-hydroxycholesterol stimulate osteoblast-like vascular cells to calcify
    • Watson KE, Bostrom K, Ravindranath R, Lam T, Norton B, Demer LL. TGF-beta 1 and 25-hydroxycholesterol stimulate osteoblast-like vascular cells to calcify. J Clin Invest 1994; 93: 2106-13.
    • (1994) J Clin Invest , vol.93 , pp. 2106-2113
    • Watson, K.E.1    Bostrom, K.2    Ravindranath, R.3    Lam, T.4    Norton, B.5    Demer, L.L.6
  • 54
    • 22144457065 scopus 로고    scopus 로고
    • Elastin-derived peptides and TGF-beta1 induce osteogenic responses in smooth muscle cells
    • Simionescu A, Philips K, Vyavahare N. Elastin-derived peptides and TGF-beta1 induce osteogenic responses in smooth muscle cells. Biochem Biophys Res Commun 2005; 334: 524-32.
    • (2005) Biochem Biophys Res Commun , vol.334 , pp. 524-532
    • Simionescu, A.1    Philips, K.2    Vyavahare, N.3
  • 55
    • 34547691571 scopus 로고    scopus 로고
    • Osteogenic responses in fibroblasts activated by elastin degradation products and transforming growth factor-beta1: Role of myofibroblasts in vascular calcification
    • Simionescu A, Simionescu DT, Vyavahare NR. Osteogenic responses in fibroblasts activated by elastin degradation products and transforming growth factor-beta1: role of myofibroblasts in vascular calcification. Am J Pathol 2007; 171: 116-23.
    • (2007) Am J Pathol , vol.171 , pp. 116-123
    • Simionescu, A.1    Simionescu, D.T.2    Vyavahare, N.R.3
  • 57
    • 34047095329 scopus 로고    scopus 로고
    • Activin-like kinase receptor 1 (ALK1) in atherosclerotic lesions and vascular mesenchymal cells
    • Yao Y, Zebboudj AF, Torres A, Shao E, Bostrom K. Activin-like kinase receptor 1 (ALK1) in atherosclerotic lesions and vascular mesenchymal cells. Cardiovasc Res 2007; 74: 279-89.
    • (2007) Cardiovasc Res , vol.74 , pp. 279-289
    • Yao, Y.1    Zebboudj, A.F.2    Torres, A.3    Shao, E.4    Bostrom, K.5
  • 58
    • 0242443189 scopus 로고    scopus 로고
    • Matrix GLA protein and BMP-2 regulate osteoinduction in calcifying vascular cells
    • Zebboudj AF, Shin V, Bostrom K. Matrix GLA protein and BMP-2 regulate osteoinduction in calcifying vascular cells. J Cell Biochem 2003; 90: 756-65.
    • (2003) J Cell Biochem , vol.90 , pp. 756-765
    • Zebboudj, A.F.1    Shin, V.2    Bostrom, K.3
  • 59
    • 33748428184 scopus 로고    scopus 로고
    • The mechanisms of uremic serum-induced expression of bone matrix proteins in bovine vascular smooth muscle cells
    • Chen NX, Duan D, O'Neill KD, Wolisi GO, Koczman JJ, Laclair R, et al. The mechanisms of uremic serum-induced expression of bone matrix proteins in bovine vascular smooth muscle cells. Kidney Int 2006; 70: 1046-53.
    • (2006) Kidney Int , vol.70 , pp. 1046-1053
    • Chen, N.X.1    Duan, D.2    O'Neill, K.D.3    Wolisi, G.O.4    Koczman, J.J.5    Laclair, R.6
  • 60
    • 40949158527 scopus 로고    scopus 로고
    • BMP-2 promotes phosphate uptake, phenotypic modulation, and calcification of human vascular smooth muscle cells
    • Li X, Yang HY, Giachelli CM. BMP-2 promotes phosphate uptake, phenotypic modulation, and calcification of human vascular smooth muscle cells. Atherosclerosis 2008; 199: 271-7.
    • (2008) Atherosclerosis , vol.199 , pp. 271-277
    • Li, X.1    Yang, H.Y.2    Giachelli, C.M.3
  • 61
    • 33646265494 scopus 로고    scopus 로고
    • Enhanced expression of the inorganic phosphate transporter Pit-1 is involved in BMP-2-induced matrix mineralization in osteoblast-like cells
    • Suzuki A, Ghayor C, Guicheux J, Magne D, Quillard S, Kakita A, et al. Enhanced expression of the inorganic phosphate transporter Pit-1 is involved in BMP-2-induced matrix mineralization in osteoblast-like cells. J Bone Miner Res 2006; 21: 674-83.
    • (2006) J Bone Miner Res , vol.21 , pp. 674-683
    • Suzuki, A.1    Ghayor, C.2    Guicheux, J.3    Magne, D.4    Quillard, S.5    Kakita, A.6
  • 64
    • 0037317032 scopus 로고    scopus 로고
    • Transglutaminases: Crosslinking enzymes with pleiotropic functions
    • Lorand L, Graham RM. Transglutaminases: crosslinking enzymes with pleiotropic functions. Nat Rev Mol Cell Biol 2003; 4:140-56.
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 140-156
    • Lorand, L.1    Graham, R.M.2
  • 65
    • 32844467767 scopus 로고    scopus 로고
    • Transglutaminases in mineralized tissues
    • Nurminskaya M, Kaartinen MT. Transglutaminases in mineralized tissues. Front Biosci 2006; 11: 1591-606.
    • (2006) Front Biosci , vol.11 , pp. 1591-1606
    • Nurminskaya, M.1    Kaartinen, M.T.2
  • 66
    • 17644372415 scopus 로고    scopus 로고
    • External GTP-bound transglutaminase 2 is a molecular switch for chondrocyte hypertrophic differentiation and calcification
    • Johnson KA, Terkeltaub RA. External GTP-bound transglutaminase 2 is a molecular switch for chondrocyte hypertrophic differentiation and calcification. J Biol Chem 2005; 280: 15004-12.
    • (2005) J Biol Chem , vol.280 , pp. 15004-15012
    • Johnson, K.A.1    Terkeltaub, R.A.2
  • 67
    • 40949152051 scopus 로고    scopus 로고
    • Transglutaminase 2 is central to induction of the arterial calcification program by smooth muscle cells
    • Johnson KA, Polewski M, Terkeltaub RA. Transglutaminase 2 is central to induction of the arterial calcification program by smooth muscle cells. Circ Res 2008; 102: 529-37.
    • (2008) Circ Res , vol.102 , pp. 529-537
    • Johnson, K.A.1    Polewski, M.2    Terkeltaub, R.A.3
  • 69
    • 2342523148 scopus 로고    scopus 로고
    • Stimulation of Na-dependent phosphate transport by platelet-derived growth factor in rat aortic smooth muscle cells
    • Kakita A, Suzuki A, Nishiwaki K, Ono Y, Kotake M, Ariyoshi Y, et al. Stimulation of Na-dependent phosphate transport by platelet-derived growth factor in rat aortic smooth muscle cells. Atherosclerosis 2004; 174: 17-24.
    • (2004) Atherosclerosis , vol.174 , pp. 17-24
    • Kakita, A.1    Suzuki, A.2    Nishiwaki, K.3    Ono, Y.4    Kotake, M.5    Ariyoshi, Y.6
  • 70
    • 1542344006 scopus 로고    scopus 로고
    • Expression, regulation, and function of IGF-1, IGF-1R, and IGF-1 binding proteins in blood vessels
    • Delafontaine P, Song YH, Li Y. Expression, regulation, and function of IGF-1, IGF-1R, and IGF-1 binding proteins in blood vessels. Arterioscler Thromb Vasc Biol 2004; 24: 435-44.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 435-444
    • Delafontaine, P.1    Song, Y.H.2    Li, Y.3
  • 71
    • 0030694431 scopus 로고    scopus 로고
    • Expression of a newly identified phosphate transporter/retrovirus receptor in human SaOS-2 osteoblast-like cells and its regulation by insulin-like growth factor I
    • Palmer G, Bonjour JP, Caverzasio J. Expression of a newly identified phosphate transporter/retrovirus receptor in human SaOS-2 osteoblast-like cells and its regulation by insulin-like growth factor I. Endocrinology 1997; 138: 5202-9.
    • (1997) Endocrinology , vol.138 , pp. 5202-5209
    • Palmer, G.1    Bonjour, J.P.2    Caverzasio, J.3
  • 72
    • 0026410980 scopus 로고
    • Regulation of insulin-like growth factor I messenger RNA levels in vascular smooth muscle cells
    • Delafontaine P, Lou H, Alexander RW. Regulation of insulin-like growth factor I messenger RNA levels in vascular smooth muscle cells. Hypertension 1991; 18: 742-7.
    • (1991) Hypertension , vol.18 , pp. 742-747
    • Delafontaine, P.1    Lou, H.2    Alexander, R.W.3
  • 73
    • 33947261951 scopus 로고    scopus 로고
    • Mechanical stress-initiated signal transduction in vascular smooth muscle cells in vitro and in vivo
    • Li C, Xu Q. Mechanical stress-initiated signal transduction in vascular smooth muscle cells in vitro and in vivo. Cell Signal 2007; 19: 881-91.
    • (2007) Cell Signal , vol.19 , pp. 881-891
    • Li, C.1    Xu, Q.2
  • 74
    • 0034623963 scopus 로고    scopus 로고
    • Estradiol decreases IGF-1 and IGF-1 receptor expression in rat aortic smooth muscle cells. Mechanisms for its atheroprotective effects
    • Scheidegger KJ, Cenni B, Picard D, Delafontaine P. Estradiol decreases IGF-1 and IGF-1 receptor expression in rat aortic smooth muscle cells. Mechanisms for its atheroprotective effects. J Biol Chem 2000; 275: 38921-8.
    • (2000) J Biol Chem , vol.275 , pp. 38921-38928
    • Scheidegger, K.J.1    Cenni, B.2    Picard, D.3    Delafontaine, P.4
  • 75
    • 14844364704 scopus 로고    scopus 로고
    • Insulin-like growth factor-I regulates proliferation and osteoblastic differentiation of calcifying vascular cells via extracellular signal-regulated protein kinase and phosphatidylinositol 3-kinase pathways
    • Radcliff K, Tang TB, Lim J, Zhang Z, Abedin M, Demer LL, et al. Insulin-like growth factor-I regulates proliferation and osteoblastic differentiation of calcifying vascular cells via extracellular signal-regulated protein kinase and phosphatidylinositol 3-kinase pathways. Circ Res 2005; 96: 398-400.
    • (2005) Circ Res , vol.96 , pp. 398-400
    • Radcliff, K.1    Tang, T.B.2    Lim, J.3    Zhang, Z.4    Abedin, M.5    Demer, L.L.6
  • 76
    • 36349028053 scopus 로고    scopus 로고
    • IGF-1 reduces inflammatory responses, suppresses oxidative stress, and decreases atherosclerosis progression in ApoE-deficient mice
    • Sukhanov S, Higashi Y, Shai SY, Vaughn C, Mohler J, Li Y, et al. IGF-1 reduces inflammatory responses, suppresses oxidative stress, and decreases atherosclerosis progression in ApoE-deficient mice. Arterioscler Thromb Vasc Biol 2007; 27: 2684-90.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 2684-2690
    • Sukhanov, S.1    Higashi, Y.2    Shai, S.Y.3    Vaughn, C.4    Mohler, J.5    Li, Y.6
  • 77
    • 0347664057 scopus 로고    scopus 로고
    • IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice
    • Holzenberger M, Dupont J, Ducos B, Leneuve P, Geloen A, Even PC. IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice. Nature 2003; 421: 182-7.
    • (2003) Nature , vol.421 , pp. 182-187
    • Holzenberger, M.1    Dupont, J.2    Ducos, B.3    Leneuve, P.4    Geloen, A.5    Even, P.C.6
  • 78
    • 0037470488 scopus 로고    scopus 로고
    • Evolutionary medicine: From dwarf model systems to healthy centenarians?
    • Longo VD, Finch CE. Evolutionary medicine: from dwarf model systems to healthy centenarians? Science 2003; 299: 1342-6.
    • (2003) Science , vol.299 , pp. 1342-1346
    • Longo, V.D.1    Finch, C.E.2
  • 79
    • 51449118038 scopus 로고    scopus 로고
    • Age-related differences in insulin-like growth factor-1 receptor signaling regulates Akt/FOXO3a and ERK/Fos pathways in vascular smooth muscle cells
    • Li M, Chiu J-F, Gagne J, Fukagawa NK. Age-related differences in insulin-like growth factor-1 receptor signaling regulates Akt/FOXO3a and ERK/Fos pathways in vascular smooth muscle cells. J Cell Physiol 2008; 217: 377-87.
    • (2008) J Cell Physiol , vol.217 , pp. 377-387
    • Li, M.1    Chiu, J.-F.2    Gagne, J.3    Fukagawa, N.K.4
  • 80
    • 35248883404 scopus 로고    scopus 로고
    • Insulin attenuates vascular smooth muscle calcification but increases vascular smooth muscle cell phosphate transport
    • Wang CC, Sorribas V, Sharma G, Levi M, Draznin B. Insulin attenuates vascular smooth muscle calcification but increases vascular smooth muscle cell phosphate transport. Atherosclerosis 2007; 195: e65-75.
    • (2007) Atherosclerosis , vol.195
    • Wang, C.C.1    Sorribas, V.2    Sharma, G.3    Levi, M.4    Draznin, B.5
  • 81
    • 0029789432 scopus 로고    scopus 로고
    • Insulin-stimulated production of nitric oxide is inhibited by wortmannin. Direct measurement in vascular endothelial cells
    • Zeng G, Quon MJ. Insulin-stimulated production of nitric oxide is inhibited by wortmannin. Direct measurement in vascular endothelial cells. J Clin Invest 1996; 98: 894-8.
    • (1996) J Clin Invest , vol.98 , pp. 894-898
    • Zeng, G.1    Quon, M.J.2
  • 82
    • 18544363627 scopus 로고    scopus 로고
    • Inhibition of phosphatidylinositol 3-kinase enhances mitogenic actions of insulin in endothelial cells
    • Montagnani M, Golovchenko I, Kim I, Koh GY, Goalstone ML, Mundhekar AN, et al. Inhibition of phosphatidylinositol 3-kinase enhances mitogenic actions of insulin in endothelial cells. J Biol Chem 2002; 277: 1794-9.
    • (2002) J Biol Chem , vol.277 , pp. 1794-1799
    • Montagnani, M.1    Golovchenko, I.2    Kim, I.3    Koh, G.Y.4    Goalstone, M.L.5    Mundhekar, A.N.6
  • 83
    • 35048842167 scopus 로고    scopus 로고
    • Diabetes-associated macrovasculopathy: Pathophysiology and pathogenesis
    • Rahman S, Rahman T, Ismail AA, Rashid AR. Diabetes-associated macrovasculopathy: pathophysiology and pathogenesis. Diabetes Obes Metab 2007; 9: 767-80.
    • (2007) Diabetes Obes Metab , vol.9 , pp. 767-780
    • Rahman, S.1    Rahman, T.2    Ismail, A.A.3    Rashid, A.R.4
  • 84
    • 0030871260 scopus 로고    scopus 로고
    • Vascular dysfunction in diabetes mellitus
    • Feener EP, King GL. Vascular dysfunction in diabetes mellitus. Lancet 1997; 350 (Suppl 1): SI9-13.
    • (1997) Lancet , vol.350 , Issue.SUPPL. 1
    • Feener, E.P.1    King, G.L.2
  • 85
    • 0031860340 scopus 로고    scopus 로고
    • Protein kinase C activation and the development of diabetic complications
    • Koya D, King GL. Protein kinase C activation and the development of diabetic complications. Diabetes 1998; 47: 859-66.
    • (1998) Diabetes , vol.47 , pp. 859-866
    • Koya, D.1    King, G.L.2
  • 86
    • 0027398167 scopus 로고
    • Diabetes mellitus induces accelerated growth of aortic smooth muscle cells: Association with overexpression of PDGF beta-receptors
    • Kawano M, Koshikawa T, Kanzaki T, Morisaki N, Saito Y, Yoshida S. Diabetes mellitus induces accelerated growth of aortic smooth muscle cells: association with overexpression of PDGF beta-receptors. Eur J Clin Invest 1993; 23: 84-90.
    • (1993) Eur J Clin Invest , vol.23 , pp. 84-90
    • Kawano, M.1    Koshikawa, T.2    Kanzaki, T.3    Morisaki, N.4    Saito, Y.5    Yoshida, S.6
  • 87
    • 38549092093 scopus 로고    scopus 로고
    • Aldosterone and vascular inflammation
    • Brown NJ. Aldosterone and vascular inflammation. Hypertension 2008; 51: 161-7.
    • (2008) Hypertension , vol.51 , pp. 161-167
    • Brown, N.J.1
  • 88
    • 21044441652 scopus 로고    scopus 로고
    • Clinical and genetic correlates of serum aldosterone in the community: The Framingham Heart Study
    • Kathiresan S, Larson MG, Benjamin EJ, Corey D, Murabito JM, Fox CS, et al. Clinical and genetic correlates of serum aldosterone in the community: the Framingham Heart Study. Am J Hypertens 2005; 18: 657-65.
    • (2005) Am J Hypertens , vol.18 , pp. 657-665
    • Kathiresan, S.1    Larson, M.G.2    Benjamin, E.J.3    Corey, D.4    Murabito, J.M.5    Fox, C.S.6
  • 90
    • 0026689952 scopus 로고
    • Immunohistochemical and biochemical evidence for a cardiovascular mineralocorticoid receptor
    • Lombes M, Oblin ME, Gasc JM, Baulieu EE, Farman N, Bonvalet JP. Immunohistochemical and biochemical evidence for a cardiovascular mineralocorticoid receptor. Circ Res 1992; 71: 503-10.
    • (1992) Circ Res , vol.71 , pp. 503-510
    • Lombes, M.1    Oblin, M.E.2    Gasc, J.M.3    Baulieu, E.E.4    Farman, N.5    Bonvalet, J.P.6
  • 91
    • 16444375794 scopus 로고    scopus 로고
    • Jaffe IZ, Mendelsohn ME. Angiotensin II and aldosterone regulate gene transcription via functional mineralocortocoid receptors in human coronary artery smooth muscle cells. Circ Res 2005; 96: 643-50.
    • Jaffe IZ, Mendelsohn ME. Angiotensin II and aldosterone regulate gene transcription via functional mineralocortocoid receptors in human coronary artery smooth muscle cells. Circ Res 2005; 96: 643-50.
  • 92
    • 0032427185 scopus 로고    scopus 로고
    • Adrenal-dependent modulation of the catalytic subunit isoforms of the Na+-K+-ATPase in aorta
    • Michea L, Valenzuela V, Bravo I, Schuster A, Marusic ET. Adrenal-dependent modulation of the catalytic subunit isoforms of the Na+-K+-ATPase in aorta. Am J Physiol 1998; 275: E1072-81.
    • (1998) Am J Physiol , vol.275
    • Michea, L.1    Valenzuela, V.2    Bravo, I.3    Schuster, A.4    Marusic, E.T.5
  • 93
    • 0033625558 scopus 로고    scopus 로고
    • Role of 11beta-hydroxysteroid dehydrogenase in nongenomic aldosterone effects in human arteries
    • Alzamora R, Michea L, Marusic ET. Role of 11beta-hydroxysteroid dehydrogenase in nongenomic aldosterone effects in human arteries. Hypertension 2000; 35: 1099-104.
    • (2000) Hypertension , vol.35 , pp. 1099-1104
    • Alzamora, R.1    Michea, L.2    Marusic, E.T.3
  • 94
    • 0032946070 scopus 로고    scopus 로고
    • Rapid actions of aldosterone: Lymphocytes, vascular smooth muscle and endothelial cells
    • Christ M, Wehling M. Rapid actions of aldosterone: lymphocytes, vascular smooth muscle and endothelial cells. Steroids 1999; 64: 35-41.
    • (1999) Steroids , vol.64 , pp. 35-41
    • Christ, M.1    Wehling, M.2
  • 95
    • 27644585370 scopus 로고    scopus 로고
    • Mineralocorticoid receptor blocker increases angiotensin-converting enzyme 2 activity in congestive heart failure patients
    • Keidar S, Gamliel-Lazarovich A, Kaplan M, Pavlotzky E, Hamoud S, Hayek T, et al. Mineralocorticoid receptor blocker increases angiotensin-converting enzyme 2 activity in congestive heart failure patients. Circ Res 2005; 97: 946-53.
    • (2005) Circ Res , vol.97 , pp. 946-953
    • Keidar, S.1    Gamliel-Lazarovich, A.2    Kaplan, M.3    Pavlotzky, E.4    Hamoud, S.5    Hayek, T.6
  • 97
    • 0035824898 scopus 로고    scopus 로고
    • Smooth muscle cell phenotypic transition associated with calcification: Upregulation of Cbfa1 and downregulation of smooth muscle lineage markers
    • Steitz SA, Speer MY, Curinga G, Yang HY, Haynes P, Aebersold R, et al. Smooth muscle cell phenotypic transition associated with calcification: upregulation of Cbfa1 and downregulation of smooth muscle lineage markers. Circ Res 2001; 89: 1147-54.
    • (2001) Circ Res , vol.89 , pp. 1147-1154
    • Steitz, S.A.1    Speer, M.Y.2    Curinga, G.3    Yang, H.Y.4    Haynes, P.5    Aebersold, R.6
  • 99
    • 4644313400 scopus 로고    scopus 로고
    • Effect of spironolactone on K(+) homeostasis and ENaC expression in lymphocytes from chronic hemodialysis patients
    • Michea L, Vukusich A, Gonzalez M, Zehnder C, Marusic ET. Effect of spironolactone on K(+) homeostasis and ENaC expression in lymphocytes from chronic hemodialysis patients. Kidney Int 2004; 66: 1647-53.
    • (2004) Kidney Int , vol.66 , pp. 1647-1653
    • Michea, L.1    Vukusich, A.2    Gonzalez, M.3    Zehnder, C.4    Marusic, E.T.5
  • 100
    • 0042320418 scopus 로고    scopus 로고
    • Aldosterone in chronic kidney and cardiac disease
    • Hostetter TH, Ibrahim HN. Aldosterone in chronic kidney and cardiac disease. J Am Soc Nephrol 2003; 14: 2395-401.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 2395-2401
    • Hostetter, T.H.1    Ibrahim, H.N.2
  • 101
    • 49849099862 scopus 로고    scopus 로고
    • Mineralocorticoid receptor antagonism attenuates cardiac hypertrophy and prevents oxidative stress in uremic rats
    • Michea L, Villagran A, Urzua A, Kuntsmann S, Venegas P, Carrasco L, et al. Mineralocorticoid receptor antagonism attenuates cardiac hypertrophy and prevents oxidative stress in uremic rats. Hypertension 2008; 52: 295-300.
    • (2008) Hypertension , vol.52 , pp. 295-300
    • Michea, L.1    Villagran, A.2    Urzua, A.3    Kuntsmann, S.4    Venegas, P.5    Carrasco, L.6
  • 102
    • 0037337818 scopus 로고    scopus 로고
    • Uremia induces the osteoblast differentiation factor Cbfa1 in human blood vessels
    • Moe SM, Duan D, Doehle BP, O'Neill KD, Chen NX. Uremia induces the osteoblast differentiation factor Cbfa1 in human blood vessels. Kidney Int 2003; 63: 1003-11.
    • (2003) Kidney Int , vol.63 , pp. 1003-1011
    • Moe, S.M.1    Duan, D.2    Doehle, B.P.3    O'Neill, K.D.4    Chen, N.X.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.