Platelet-derived growth factor stimulates sodium-dependent P(i) transport in osteoblastic cells via phospholipase Cγ and phosphatidylinositol 3'-kinase

Journal of Bone and Mineral Research

Volumn 12, Issue 1, 1997, Pages 36-44

  Zhen, Xuechu ^a   Bonjour, Jean Philippe ^a   Caverzasio, Joseph ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOLIPASE C; PLATELET DERIVED GROWTH FACTOR;

ANIMAL CELL; ARTICLE; BONE MATRIX; CALCIFICATION; CELL MEMBRANE; CELL METABOLISM; ENZYME ACTIVATION; ENZYME ACTIVITY; ION TRANSPORT; MOUSE; NONHUMAN; OSTEOBLAST; PHOSPHATE TRANSPORT; PHOSPHOINOSITIDE METABOLISM; PROTEIN PHOSPHORYLATION; PROTON SODIUM EXCHANGE; SIGNAL TRANSDUCTION; TRANSLATION REGULATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; 3T3 CELLS; ANIMALS; ANTICOAGULANTS; BIOLOGICAL TRANSPORT, ACTIVE; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL MEMBRANE; CELLS, CULTURED; CHROMONES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; ENZYME INHIBITORS; ISOENZYMES; MICE; MORPHOLINES; OSTEOBLASTS; PHOSPHATES; PHOSPHOLIPASE C; PHOSPHOLIPASE C GAMMA; PHOSPHORYLATION; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PLATELET-DERIVED GROWTH FACTOR; PROTEIN BIOSYNTHESIS; PROTEIN-TYROSINE KINASES; PYRIDINES; PYRIMIDINES; RECEPTORS, PLATELET-DERIVED GROWTH FACTOR; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; SODIUM;

EID: 0031038098     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.1997.12.1.36     Document Type: Article

References (44)

1. Ross R, Raines EW, Bowen-Pope DF 1986 The biology of platelet-derived growth factor. Cell 46:155-169.
2. + exchange by platelet-derived growth factor involves phosphatidylinositol 3′ kinase and phospholipase Cγ. J Biol Chem 269:30734-30739.
3. Holmsen H, Male R, Rongved S, Langeland N, Lillehang J 1989 Platelet-derived growth factor stimulated heterogeneous polyphosphoinositide metabolism and phosphate uptake in C3H fibroblasts. Biochem J 260:589-592.
4. Montessuit C, Caverzasio J, Bonjour J-P 1991 Characterization of a Pi transport system in cartilage matrix vesicles: Potential role in the calcification process. J Biol Chem 266:17791-17797.
5. Caverzasio J, Bonjour J-P 1996 Characteristics of Pi transport in osteogenic cells for bone metabolism. Kidney Int 49:975-980.
6. Anderson HC 1985 Matrix vesicle calcification: Review and update. In: Peck WA (ed) Elsevier Science Publisher BV Amsterdam New York, Oxford Bone and Mineral Research 3:109-150.
7. Caverzasio J, Bonjour J-P 1992 Tyrosine phosphorylation selectively regulates renal cellular phosphate transport. Evidence that it mediates the stimulatory effect of IGF-1. Endocrinology 130:373-380.
8. Claesson-Welsh L 1994 Signal transduction by the PDGF receptors. Prog Growth Factor Res 5:37-54.
9. Heldin CH, Westermark B 1990 Platelet-derived growth factor: Mechanism of action and possible in vivo function. Cell Regul 1:555-566.
10. Hart CE, Forstrom JW, Kelly JD, Seifert RE, Ross R, Murray MJ, Bowen-Pope DF 1988 Two classes of PDGF receptors recognize different isoforms of PDGF. Science 240:1529-1531.
11. Heldin CH, Bäckström G, Oestman A, Hammacher A, Rönnstrand L, Rubin K, Nister M, Westermark B 1988 Binding of different dimeric forms of PDGF to human fibroblasts: evidence for two seperate receptor types. EMBO J 7:1387-1394.
12. Heldin CH, Erlund A, Rorsman C, Rönstrand L 1989 Dimerization of B type PDGF receptors occurs after ligand binding and is closely associated with receptor kinase activation. J Biol Chem 264:8905-8912.
13. Kelly JD, Haldeman BA, Grant FJ, Murray MJ, Seifert RA, Bowen-Pope DF, Cooper JA, Kazlauskas A 1991 Platelet-derived growth factor (PDGF) stimulates PDGF receptor subunit dimerization and intersubunit trans-phosphorylation. J Biol Chem 266:8987-8992.
14. Escobedo JA, Barr PJ, Williams LT 1988 Role of tyrosine kinase and membrane-spanning domains in signal transduction by the platelet-derived growth factor receptor. Mol Cell Biol 8:5126-5131.
15. Cleasson-Welsh L 1994 Platelet-derived growth factor receptor signals. J Biol Chem 269:32023-32026.
16. Kumjian DA, Wahl MI, Rhee SG, Daniel TO 1989 Platelet-derived growth factor (PDGF) binding promotes physical association of PDGF receptor with phospholipase Cγ. Proc Natl Acad Sci USA 86:8232-8236.
17. Meisenhelder J, Suh PG, Rhee SG, Hunter T. 1989 Phospholipase Cγ is a substrate for the PDGF and EGF receptor protein-kinases in vivo and in vitro. Cell 57:1109-1122.
18. Wahl MW, Olashaw NE, Nishibe S, Rhee SG, Pledger WJ, Carpenter G 1989 Platelet-derived growth factor induces rapid and sustained tyrosine phosphorylation of phospholipase Cγ in quiescent BALB/c 3T3 cells. Mol Cell Biol 9:2934-2943.
19. Morrison DK, Kaplan DR, Rhee SG, William LT 1990 Platelet-derived growth factor (PDGF)-dependent association of phospholipase Cγ with the PDGF receptor signaling complex. Mol Cell Biol 10:2359-2366.
20. Coughlin SR, Escobedo JA, William LT 1989 Role of phosphatidylinositol kinase in PDGF receptor signal transduction. Science 243:1191-1194.
21. Cantley LC, Auger KR, Carpenter C, Duckworth B, Graziani A, Kapeller R, Soltoff S 1991 Oncogenes and signal transduction. Cell 64:281-302.
22. Xiao S, Rose DW, Sasaoka T, Maegawa H, Burke TR Jr, Roller PP, Shoelson SE, Olefsky J M 1994 SyP (SH-PTP2) is a positive mediator of growth factor-stimulated mitogenic signal transduction. J Biol Chem 269:21244-21248.
23. Molloy CJ, Bottaro DP, Fleming TP, Marshall MS, Gibbs JB, Aaronson SA 1989 PDGF induction of tyrosine phosphorylation of GTPase activating proteins. Nature 342:711-714.
24. Kaplan DR, Morrison DK, Wong J, McCormick F, Williams LT 1990 PDGFβ-receptor stimulates tyrosine phosphorylation of GAP and association of GAP with a signaling complex. Cell 61:125-133.
25. Kazlauskas A, Ellis C, Pawson T, Cooper JA 1990 Binding of GAP to activated PDGF receptors. Science 247:1578-1581.
26. Selz T, Caverzasio J, Bonjour J-P 1989 Regulation of Na-dependent phosphate transport in osteoblast-like cells. Am J Physiol 256:E93-E100.
27. Burton K 1956 A study of the condition and the mechanism of the diphenylamine reaction for the colorimetric estimation of desoxyribonucleic acid. Biochem J 62:315-323.
28. Buchdunger E, Zimmermann J, Mett H, Meyer T, Müller M, Regenass U, Lydon NB 1995 Selective inhibition of the platelet-derived growth factor signal transduction pathway by a protein-tyrosine kinase inhibitor of the 2-phenylaminopyrimidine class. Proc Natl Acad Sci USA 92:2558-2562.
29. Wu J, Dent P, Jenikek T, Wolfman A, Weber MJ, Sturgill TW 1993 Inhibition of the EGF-activated MAP kinase signaling pathway by adenosine 3′,5′-monophosphate. Science 262:1065-1069.
30. Laemmli UK 1970 Cleavage of structural proteins during the assembly of the head of bacteriofage T4. Nature 227:680-685.
31. Johnson JL, Vaillancourt RR 1994 Sequential protein kinase reactions controlling cell growth and differentiation. Curr Opin Cell Biol 6:230-238.
32. Sevetson BR, Kong XM, Lawrence JC 1993 Increasing cAMP attenuates activation of mitogen-activated protein kinase. Proc Natl Acad Sci USA 90:1035-1039.
33. Hordijk PL, Verlaan I, Jalink K, Vancovern EJ, Moolenaar WH 1994 cAMP abrogates the p21 ras-mitogen-activated protein kinase pathway in fibroblasts. J Biol Chem 269:3534-3538.
34. Selz T, Caverzasio J, Bonjour J-P 1989 Regulation of Na-dependent Pi transport by parathyroid hormone in osteoblast-like cells. Am J Physiol 256:E93-E100.
35. Arao M, Yamaguchi T, Sugimoto T, Fukase M, Chihara K 1994 Involvement of protein kinase C in the stimulation of sodium-dependent phosphate transport by parathyroid hormone in osteoblast-like cells. Eur J Endocrinol 131:646-651.
36. Okada T, Kawano Y, Sakakibara T, Hazeki O, Ui M 1994 Essential role of phosphatidylinositol 3-kinase in insulin-induced glucose transport and antilipolysis in rat adipocytes. J Biol Chem 269:3568-3573.
37. Vlahos CJ, Matter WF, Hui KY, Brown RF 1994 A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002). J Biol Chem 269:5241-5248.
38. i transport in cultured kidney cells. Am J Physiol 257:F712-F717.
39. Caverzasio J, Brown CDA, Biber J, Bonjour J-P, Murer H 1985 Adaptation of phosphate transport in phosphate-deprived LLC-PK1 cells. Am J Physiol 248:F122-F127.
40. i diet in rat kidney cortex. J Biol Chem 269:6637-6639.
41. Levi M, Lötscher M, Sorribas V, Custer M, Arar M, Kaissling B, Murer H, Biber J 1994 Cellular mechanisms of acute and chronic adaptation of rat renal Pi transport to alterations in dietary Pi. Am J Physiol 267:F900-F908.
42. Caverzasio J, Imai T, Bonjour J-P 1996 Aluminum potentiates the effect of fluoride on tyrosine phosphorylation and osteoblast replication in vitro and bone mass in vivo. J Bone Miner Res 11:46-55.
43. Yatomi Y, Hazeki O, Kume S, Ui M 1992 Suppression by wortmannin of platelet response to stimuli due to inhibition of pleckstrin phosphorylation. Biochem J 285:745-751.
44. Hara K, Yonezawa K, Sakaue H, Ando A, Kotani K, Kitamura T, Kitamura Y, Ueda H, Stephens L, Jackson TR, Hawkins PT, Dhand R, Clark AE, Holman GD, Waterfield MD, Kasuga M 1994 1-phosphatidylinositol 3-kinase activity is required for insulin-stimulated glucose transport but not for Ras activation in CHO cells Proc Natl Acad Sci USA 91:7415-7419.