Discovery of novel antileishmanial agents in an attempt to synthesize pentamidine - Aplysinopsin hybrid molecule

Journal of Medicinal Chemistry

Volumn 52, Issue 19, 2009, Pages 5793-5802

  Porwal, Sharad ^a   Chauhan, Shikha S ^a   Chauhan, Prem M S ^a   Shakya, Nishi ^a   Verma, Aditya ^a   Gupta, Suman ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

1 (4 CYANOPHENOXYPENTYL)INDOLE 3 CARBALDEHYDE; ANTILEISHMANIAL AGENT; APLYSINOPSIN; PENTAMIDINE; UNCLASSIFIED DRUG;

AMASTIGOTE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIMICROBIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DIASTEREOISOMER; DRUG STRUCTURE; DRUG SYNTHESIS; FEMALE; LEISHMANIA DONOVANI; MALE; NONHUMAN; PROMASTIGOTE; SYRIAN HAMSTER;

ANIMALS; ANTIPROTOZOAL AGENTS; CELL LINE; DRUG DISCOVERY; INDOLES; INHIBITORY CONCENTRATION 50; LEISHMANIA DONOVANI; MACROPHAGES; MICE; PARASITIC SENSITIVITY TESTS; PENTAMIDINE; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPTOPHAN;

EID: 70349643110     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm900564x     Document Type: Article

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