Synthesis and biological evaluation of s-triazine substituted polyamines as potential new anti-Trypanosomal drugs

Journal of Medicinal Chemistry

Volumn 44, Issue 21, 2001, Pages 3440-3452

  Klenke, B ^a   Stewart, M ^b   Barrett, M P ^b   Brun, R ^c   Gilbert, I H ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

^c SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE; ANTITRYPANOSOMAL AGENT; CARRIER PROTEIN; MELAMINE; POLYAMINE DERIVATIVE; TRIAZINE;

ANIMAL CELL; ANTIPROTOZOAL ACTIVITY; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DOSE RESPONSE; DRUG DESIGN; DRUG PROTEIN BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; MOUSE; NONHUMAN; STRUCTURE ACTIVITY RELATION; TRYPANOSOMA BRUCEI; TRYPANOSOMA CRUZI; TRYPANOSOMA RHODESIENSE; TRYPANOSOMIASIS;

ADENOSINE; ANIMALS; BIOLOGICAL TRANSPORT; CARRIER PROTEINS; CELL LINE; POLYAMINES; PROTOZOAN PROTEINS; RATS; STRUCTURE-ACTIVITY RELATIONSHIP; TRIAZINES; TRYPANOCIDAL AGENTS; TRYPANOSOMA BRUCEI BRUCEI; TRYPANOSOMA CRUZI;

EID: 0035846173     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm010854+     Document Type: Article

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