Sex-dependent differences in Rho activation contribute to contractile dysfunction in type 2 diabetic mice

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 297, Issue 4, 2009, Pages

  Nuno, Daniel W ^a   Harrod, Jeremy S ^a   Lamping, Kathryn G ^a,b  

^a UNIVERSITY OF IOWA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Rho guanosine 3 ,5 triphosphatase; Rho kinase; RhoA; Serotonin

Indexed keywords

ACETYLCHOLINE; FASUDIL; NITROPRUSSIDE SODIUM; RHO KINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SEROTONIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; FEMALE; HEART DISEASE; HEART MUSCLE CONTRACTILITY DYSFUNCTION; MALE; MOUSE; MUSCLE RELAXATION; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEX DIFFERENCE;

ANIMALS; AORTA; AORTIC DISEASES; DIABETES MELLITUS, TYPE 2; DIABETIC ANGIOPATHIES; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; FEMALE; MALE; MICE; MICE, INBRED C57BL; NITRIC OXIDE; PROTEIN KINASE INHIBITORS; RHO GTP-BINDING PROTEINS; RHO-ASSOCIATED KINASES; SEROTONIN; SEX FACTORS; VASODILATION; VASODILATOR AGENTS;

EID: 70349616568     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00407.2009     Document Type: Article

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