메뉴 건너뛰기




Volumn 69, Issue 1, 2009, Pages 28-33

Correcting for cryptic relatedness in population-based association studies of continuous traits

Author keywords

Cryptic relatedness; Likelihood ratio tests; Population based association studies

Indexed keywords

ARTICLE; CONTROLLED STUDY; GENETIC TRAIT; HEREDITY; HUMAN; POPULATION GENETICS; STATISTICAL MODEL;

EID: 70349608363     PISSN: 00015652     EISSN: 14230062     Source Type: Journal    
DOI: 10.1159/000243151     Document Type: Article
Times cited : (6)

References (36)
  • 1
    • 0032427048 scopus 로고    scopus 로고
    • The relative power of family-based and case-control designs for linkage disequilibrium studies of complex human diseases i
    • Risch N, Teng J: The relative power of family-based and case-control designs for linkage disequilibrium studies of complex human diseases I. DNA pooling. Genome Res 1998; 8: 1273-1288.
    • (1998) DNA Pooling. Genome Res , vol.8 , pp. 1273-1288
    • Risch, N.1    Teng, J.2
  • 2
    • 0032530165 scopus 로고    scopus 로고
    • Tests and estimates of allelic association in complex inheritance
    • Morton NE, Collins A: Tests and estimates of allelic association in complex inheritance. Proc Natl Acad Sci USA 1998; 95: 11 3 8 9-11393.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 11389-11393
    • Morton, N.E.1    Collins, A.2
  • 3
    • 0029741063 scopus 로고    scopus 로고
    • The future of genetic studies of complex human diseases
    • Risch N, Merikangas K: The future of genetic studies of complex human diseases. Science 1996; 273: 1 516-1 5 17.
    • (1996) Science , vol.273 , pp. 1516-1517
    • Risch, N.1    Merikangas, K.2
  • 8
    • 0035679875 scopus 로고    scopus 로고
    • Population admixture may appear to mask, change or reverse genetic effects of genes underlying complex traits
    • Deng HW: Population admixture may appear to mask, change or reverse genetic effects of genes underlying complex traits. Genetics 2001; 159: 1319-1323.
    • (2001) Genetics , vol.159 , pp. 1319-1323
    • Deng, H.W.1
  • 9
    • 0034758055 scopus 로고    scopus 로고
    • The importance of genealogy in determining genetic associations with complex traits
    • Newman DL, Abney M, McPeek MS, Ober C, Cox NJ: The importance of genealogy in determining genetic associations with complex traits. Am J Hum Genet 2001; 69:1146-1148.
    • (2001) Am J Hum Genet , vol.69 , pp. 1146-1148
    • Newman, D.L.1    Abney, M.2    McPeek, M.S.3    Ober, C.4    Cox, N.J.5
  • 10
    • 58149348419 scopus 로고    scopus 로고
    • Genome-wide association studies: Implications for multiethnic samples
    • Cooper RS, Tayo B, Zhu X: Genome-wide association studies: implications for multiethnic samples. Hum Mol Genet 2008; 17:R151-R155.
    • (2008) Hum Mol Genet , vol.17
    • Cooper, R.S.1    Tayo, B.2    Zhu, X.3
  • 12
    • 0034118493 scopus 로고    scopus 로고
    • Inference of population structure using multilo-cus genotype data
    • Pritchard JK, Stephens M, Donnelly P: Inference of population structure using multilo-cus genotype data. Genetics 2000; 155:945-959.
    • (2000) Genetics , vol.155 , pp. 945-959
    • Pritchard, J.K.1    Stephens, M.2    Donnelly, P.3
  • 13
    • 0036668723 scopus 로고    scopus 로고
    • Association mapping, using a mixture model for complex traits
    • Zhu X, Zhang S, Zhao H, Cooper RS: Association mapping, using a mixture model for complex traits. Genet Epidemiol 2002; 23: 181-196.
    • (2002) Genet Epidemiol , vol.23 , pp. 181-196
    • Zhu, X.1    Zhang, S.2    Zhao, H.3    Cooper, R.S.4
  • 14
    • 40749128980 scopus 로고    scopus 로고
    • A unified association analysis approach for family and unrelated samples correcting for stratification
    • Zhu X, Li S, Cooper RS, Elston RC: A unified association analysis approach for family and unrelated samples correcting for stratification. Am J Hum Genet 2008; 82: 352-365.
    • (2008) Am J Hum Genet , vol.82 , pp. 352-365
    • Zhu, X.1    Li, S.2    Cooper, R.S.3    Elston, R.C.4
  • 15
    • 0037228081 scopus 로고    scopus 로고
    • On a semiparamet-ric test to detect associations between quantitative traits and candidate genes using unrelated individuals
    • Zhang S, Zhu X, Zhao H: On a semiparamet-ric test to detect associations between quantitative traits and candidate genes using unrelated individuals. Genet Epidemiol 2003; 24:44-56.
    • (2003) Genet Epidemiol , vol.24 , pp. 44-56
    • Zhang, S.1    Zhu, X.2    Zhao, H.3
  • 16
    • 1542330236 scopus 로고    scopus 로고
    • Qualitative semi-parametric test for genetic associations in case-control designs under structured populations
    • Chen HS, Zhu X, Zhao H, Zhang S: Qualitative semi-parametric test for genetic associations in case-control designs under structured populations. Ann Hum Genet 2003; 67: 250-264.
    • (2003) Ann Hum Genet , vol.67 , pp. 250-264
    • Chen, H.S.1    Zhu, X.2    Zhao, H.3    Zhang, S.4
  • 18
    • 0032714352 scopus 로고    scopus 로고
    • Genomic control for association studies
    • Devlin B, Roeder K: Genomic control for association studies. Biometrics 1999; 55:997-1004.
    • (1999) Biometrics , vol.55 , pp. 997-1004
    • Devlin, B.1    Roeder, K.2
  • 19
    • 33646694298 scopus 로고    scopus 로고
    • Confounding from cryptic relatedness in case-control association studies
    • Voight BF, Pritchard JK: Confounding from cryptic relatedness in case-control association studies. PLoS Genet 2005; 1:e32.
    • (2005) PLoS Genet , vol.1
    • Voight, B.F.1    Pritchard, J.K.2
  • 20
    • 0034994415 scopus 로고    scopus 로고
    • Evaluation of candidate genes in case-control studies: A statistical method to account for related subjects
    • Slager SL, Schaid DJ: Evaluation of candidate genes in case-control studies: a statistical method to account for related subjects. Am J Hum Genet 20 01; 68: 14 5 7-14 6 2.
    • (2001) Am J Hum Genet , vol.68 , pp. 1457-1462
    • Slager, S.L.1    Schaid, D.J.2
  • 22
    • 0036201581 scopus 로고    scopus 로고
    • Quantitative-trait homozygosity and association mapping and empirical genome-wide significance in large, complex pedigrees: Fasting serum-insulin level in the Hutterites
    • Abney M, Ober C, McPeek MS: Quantitative-trait homozygosity and association mapping and empirical genome-wide significance in large, complex pedigrees: fasting serum-insulin level in the Hutterites. Am J Hum Genet 20 02; 70: 920-934.
    • (2002) Am J Hum Genet , vol.70 , pp. 920-934
    • Abney, M.1    Ober, C.2    McPeek, M.S.3
  • 23
    • 34247585477 scopus 로고    scopus 로고
    • A simple and improved correction for population stratification in case-control studies
    • Epstein MP, Allen AS, Satten GA: A simple and improved correction for population stratification in case-control studies. Am J Hum Genet 2007; 80:921-930.
    • (2007) Am J Hum Genet , vol.80 , pp. 921-930
    • Epstein, M.P.1    Allen, A.S.2    Satten, G.A.3
  • 24
    • 33745673631 scopus 로고    scopus 로고
    • Testing for association in the presence of population stratification: A simulation study comparing the S-TDT, STRAT and the GC
    • Wawro N, Bammann K, Pigeot I: Testing for association in the presence of population stratification: a simulation study comparing the S-TDT, STRAT and the GC. Biom J 2006; 48: 420-434.
    • (2006) Biom J , vol.48 , pp. 420-434
    • Wawro, N.1    Bammann, K.2    Pigeot, I.3
  • 25
    • 54449089328 scopus 로고    scopus 로고
    • Comparison of population-based association study methods correcting for population stratification
    • Zhang F, Wang Y, Deng HW: Comparison of population-based association study methods correcting for population stratification. PLoS ONE 2008; 3:e3392.
    • (2008) PLoS ONE , vol.3
    • Zhang, F.1    Wang, Y.2    Deng, H.W.3
  • 26
    • 84971185409 scopus 로고
    • The correlation between relatives on the supposition of Mendelian inheritance
    • Fisher R: The correlation between relatives on the supposition of Mendelian inheritance. Trans R Soc Edinb 1918; 52:399-433.
    • (1918) Trans R Soc Edinb , vol.52 , pp. 399-433
    • Fisher, R.1
  • 28
    • 0028058128 scopus 로고
    • Robust variance-components approach for assessing genetic linkage in pedigrees
    • Amos CI: Robust variance-components approach for assessing genetic linkage in pedigrees. Am J Hum Genet 1994; 54:535-543.
    • (1994) Am J Hum Genet , vol.54 , pp. 535-543
    • Amos, C.I.1
  • 29
    • 0025245437 scopus 로고
    • Multipoint analysis of human quantitative genetic variation
    • Goldgar DE: Multipoint analysis of human quantitative genetic variation. Am J Hum Genet 1990; 47: 957-967.
    • (1990) Am J Hum Genet , vol.47 , pp. 957-967
    • Goldgar, D.E.1
  • 30
    • 0031966959 scopus 로고    scopus 로고
    • Multipoint quantitative-trait linkage analysis in general pedigrees
    • Almasy L, Blangero J: Multipoint quantitative-trait linkage analysis in general pedigrees. Am J Hum Genet 1998; 62: 119 8-1 211.
    • (1998) Am J Hum Genet , vol.62 , pp. 1198-1211
    • Almasy, L.1    Blangero, J.2
  • 33
    • 70350734992 scopus 로고    scopus 로고
    • R-Development-Core-Team: R: A language and environment for statistical computing. Vienna, Austria, 2007
    • R-Development-Core-Team: R: A language and environment for statistical computing. Vienna, Austria, 2007.
  • 34
    • 0034940158 scopus 로고    scopus 로고
    • The value of isolated populations
    • Shifman S, Darvasi A: The value of isolated populations. Nat Genet 2001; 28: 309-310.
    • (2001) Nat Genet , vol.28 , pp. 309-310
    • Shifman, S.1    Darvasi, A.2
  • 35
    • 0028090414 scopus 로고
    • Genetic dissection of complex traits
    • Lander ES, Schork NJ: Genetic dissection of complex traits. Science 1994; 265:2037-2048.
    • (1994) Science , vol.265 , pp. 2037-2048
    • Lander, E.S.1    Schork, N.J.2
  • 36
    • 0032707163 scopus 로고    scopus 로고
    • Population choice in mapping genes for complex diseases
    • Wright AF, Carothers AD, Pirastu M: Population choice in mapping genes for complex diseases. Nat Genet 1999; 23:397-404.
    • (1999) Nat Genet , vol.23 , pp. 397-404
    • Wright, A.F.1    Carothers, A.D.2    Pirastu, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.