Association of common type 2 diabetes risk gene variants and posttransplantation diabetes mellitus in renal allograft recipients in Korea

Transplantation

Volumn 88, Issue 5, 2009, Pages 693-698

  Kang, Eun Seok ^a   Kim, Myoung Soo ^b,c   Kim, Chul Hoon ^a   Nam, Chung Mo ^a   Han, Seung Jin ^a,d   Hur, Kyu Yeon ^a,e   Ahn, Chul Woo ^a   Cha, Bong Soo ^a   Kim, Soon Il ^b,c   Lee, Hyun Chul ^a   Kim, Yu Seun ^b,c  

^a Yonsei University College of Medicine   (South Korea)

^b Yonsei University   (South Korea)

^c Yonsei University College of Medicine   (South Korea)

^d Ajou University   (South Korea)

^e Samsung Medical Center   (South Korea)

Author keywords

Genetic variation; Kidney transplantation; Posttransplantation diabetes mellitus

Indexed keywords

ADAMTS 9 PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 2A; CYCLIN DEPENDENT KINASE INHIBITOR 2B; GLUCOSE; METALLOPROTEINASE; NOTCH2 RECEPTOR; POTASSIUM CHANNEL KCNQ1; SOMATOMEDIN BINDING PROTEIN 2; TRANSCRIPTION FACTOR 7 LIKE 2; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CDC123 GENE; CDKAL1 GENE; CONTROLLED STUDY; DIABETES MELLITUS; FEMALE; FTO GENE; GENE; GENE FREQUENCY; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENOTYPE; GLUCOSE BLOOD LEVEL; GRAFT RECIPIENT; HHEX GENE; HUMAN; JAZF1 GENE; KIDNEY TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; POSTOPERATIVE COMPLICATION; POSTTRANSPLANTATION DIABETES MELLITUS; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM; SLC30A8 GENE; SOUTH KOREA; THADA GENE; TSPAN8 GENE; WFS1 GENE; COHORT ANALYSIS; GENETIC PREDISPOSITION; GENETICS; KIDNEY FAILURE; KOREA; METABOLISM; METHODOLOGY; MIDDLE AGED;

ADULT; COHORT STUDIES; DIABETES COMPLICATIONS; DIABETES MELLITUS, TYPE 2; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; GLUCOSE; HUMANS; KIDNEY FAILURE; KIDNEY TRANSPLANTATION; KOREA; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 70349580509     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/TP.0b013e3181b29c41     Document Type: Article

References (35)

1. 1. Hjelmesaeth J, Hartmann A, Leivestad T, et al. The impact of earlydiagnosed new-onset post-transplantation diabetes mellitus on survival and major cardiac events. Kidney Int 2006; 69: 588. (Pubitemid 43164454)
2. 2. Cosio FG, Kudva Y, van der Velde M, et al. New onset hyperglycemia and diabetes are associated with increased cardiovascular risk after kidney transplantation. Kidney Int 2005; 67:2415. (Pubitemid 41623405)
3. 3. Kasiske BL, Snyder JJ, Gilbertson D, et al. Diabetes mellitus after kidney transplantation in the United States. Am J Transplant 2003; 3: 178. (Pubitemid 36323115)
4. 4. Hjelmesaeth J, Hartmann. A, Kofstad J, et al. Glucose intolerance after renal transplantation depends upon prednisolone dose and recipient age. Transplantation 1997; 64: 979. (Pubitemid 27446762)
5. 5. Rodrigo E, Fernandez-Fresnedo G, Valero R, et. aL New-onset diabetes after kidney transplantation: Risk factors. J Am Soc Nephrol 2006; 17(12 suppl 3): S291. (Pubitemid 44865264)
6. 6. Markell M. New-onset diabetes mellitus in transplant patients: Pathogenesis, complications, and management. Am J Kidney Dis 2004; 43: 953. (Pubitemid 38691490)
7. Hamer RA, Chow CL, Ong AC, et al. Polycystic kidney disease is a risk factor for new-onset diabetes after transplantation. Transplantation 2007; 83: 36.
8. Nam JH, Lee HC, Kim YH, et al. Identification of glucokinase mutation in subjects with post-renal transplantation diabetes mellitus. Diabetes Res Clin Pract 2000; 50: 169.
9. 9. Torres-Romero LF, Santiago-Delpin EA, de Echegaray S, et al. HLA is not predictive of posttransplant diabetes mellitus. Transplant Proc 2006; 38: 914. (Pubitemid 44389511)
10. 10. Numakura K, Satoh S, Tsuchiya N, et al. Clinical and genetic risk factors for posttransplant diabetes mellitus in adult renal transplant recipients treated with tacrolimus. Transplantation 2005; 80: 1419. (Pubitemid 41803623)
11. Kang ES, Kim MS, Kim YS, et al. A variant of the transcription factor 7-like 2 (TCF7L2) gene and the risk of posttransplantation diabetes mellitus in renal allograft recipients. Diabetes Care 2008; 31: 63.
12. Kang ES, Kim MS, Kim YS, ct al. A polymorphism in the zinc transporter gene SLC30A8 confers resistance against posttransplantation diabetes mellitus in renal allograft recipients. Diabetes 2008; 57: 1043.
13. 13. Sladek R, Rocheleau G, Rung J, et al. A genome-wide association study identifies novel risk loci for type 2 diabetes. Nature 2007; 445: 881. (Pubitemid 46309843)
14. 14. Steinthorsdottir V, Thorleifsson G, Reynisdottir I, et al. A variant in CDKAL1 influences insulin response and risk of type 2 diabetes. Nat Genet 2007; 39: 770. (Pubitemid 46848592)
15. Scott LJ, Mohlke KL, Bonnycastle LL, et al. A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science 2007; 316: 1341.
16. 16. Zeggini E, Weedon MN, Lindgren CM, et al. Replication of genomewide association signals in UK samples reveals risk loci, for type 2 diabetes. Science 2007; 316: 1336. (Pubitemid 46871654)
17. 17. Saxena R, Voight BF, Lyssenko V, et al. Genome-wide association analysis identifies loci, for type 2 diabetes and triglyceride levels. Science 2007; 316: 1331. (Pubitemid 46871653)
18. 18. Zeggini E, Scott LJ, Saxena R, et al. Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet 2008; 40: 638. (Pubitemid 351601209)
19. Unoki H, Takahashi A, Kawaguchi T, et al. SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations. Nat Genet 2008; 40: 1098.
20. Yasuda K, Miyake K, Horikawa Y, et al. Variants in KCNQl are associated with susceptibility to type 2 diabetes mellitus. Nat Genet 2008; 40: 1092.
21. Davidson J, Wilkinson A, Dantal J, et al. New-onset diabetes after transplantation: 2003 International consensus guidelines. Proceedings of an international expert panel meeting. Barcelona, Spain, February 19, 2003. Transplantation 2003; 75(10 suppl): SS3.
22. Sulanc E, Lane JT, Puumala SE, et al. New-onset diabetes after kidney transplantation: An application of 2003 International Guidelines. Transplantation 2005; 80: 945.
23. 23. Wilkinson A, Davidson J, Dotta F, et al. Guidelines for the treatment and management of new-onset diabetes after transplantation. Clin Transplant 2005; 19: 291. (Pubitemid 40711959)
24. Sandhu MS, Weedon MN, Fawcett KA, et al. Common variants in WFSl confer risk of type 2 diabetes. Nat Genet 2007; 39: 951.
25. Palmer ND, Goodarzi MO, Langefeld CD, et al. Quantitative trait analysis of type 2 diabetes susceptibility loci identified from whole genome association studies in the Insulin Resistance Atherosclerosis Family Study. Diabetes 2008; 57: 1093.
26. Hur KY, Kim MS, Kim YS, et al. Risk factors associated with, the onset and progression of posttransplantation diabetes in renal allograft recipients. Diabetes Care 2007; 30: 609.
27. Horikoshi M, Hara K, Ito C, et al. Variations in the HHEX gene are associated with increased risk of type 2 diabetes in the Japanese population. Diabetologia 2007; 50: 246.1.
28. Furukawa Y, Snimada T, Furuta H, et al. Polymorphisms in the IDE-KIF11-HHEX gene locus are reproducibly associated with type 2 diabetes in a Japanese population. J Clin Endocrinol Metab 2008; 93:310.
29. Horikawa Y, Miyake K, Yasuda K, et al. Replication of genome-wide association studies of type 2 diabetes susceptibility in Japan. / Clin Endocrinol Metab 2008; 93: 3136.
30. Omori S, Tanaka Y, Takahashi A, et al. Association of CDKALl, IGF2BP2, CDKN2A/B, HHEX, SLC30A8, and KCNJ11 with susceptibility to type 2 diabetes in a Japanese population. Diabetes 2008; 57:791.
31. Ng MC, Park KS, Oh B, et al. Implication of genetic variants near TCF7L2, SLC30A8, HHEX, CDKALl, CDKN2A/B, IGF2BP2, and FTO in type 2 diabetes and obesity in 6,719 Asians. Diabetes 2008; 57: 2226.
32. Lee YH, Kang ES, Kim SH, et al. Association between polymorphisms in SLC30A8, HHEX, CDKN2A/B, IGF2BP2, FTO, WFSl, CDKAL1, KCNQ1 and type 2 diabetes in the Korean population. J Hum Genet 2008; 53: 991.
33. Frayling TM, Timpson NJ, Weedon MN, et al. A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science 2007; 316: 889.
34. 34. Bamoulid J, Courivaud C, Deschamps M, et al. IL-6 promoter polymorphism -174 is associated with new-onset diabetes after transplantation. JAm SocNephrol 2006; 17: 2333. (Pubitemid 44141925)
35. Nam JH, Mun JI, Kim SI, et al. β-Cell dysfunction rather than, insulin resistance is the main contributing factor for the development of postrenal transplantation diabetes mellitus. Transplantation 2001; 71:1417.