메뉴 건너뛰기




Volumn 114, Issue 8, 2009, Pages 1585-1595

The proteomic signature of NPM/ALK reveals deregulation of multiple cellular pathways

Author keywords

[No Author keywords available]

Indexed keywords

ANAPLASTIC LYMPHOMA KINASE; MAMMALIAN TARGET OF RAPAMYCIN; NUCLEOPHOSMIN; PROTEIN P42; PROTEIN P44; RAS PROTEIN; P80(NPM ALK) PROTEIN; P80(NPM-ALK) PROTEIN; PROTEIN TYROSINE KINASE; PROTEOME; S6 KINASE;

EID: 70349569567     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2009-02-204735     Document Type: Article
Times cited : (49)

References (39)
  • 1
    • 0030658039 scopus 로고    scopus 로고
    • Oncogenic transcription factors in the human acute leukemias
    • DOI 10.1126/science.278.5340.1059
    • Look AT. Oncogenic transcription factors in the human acute leukemias. Science. 1997;278(5340):1059-1064. (Pubitemid 27517875)
    • (1997) Science , vol.278 , Issue.5340 , pp. 1059-1064
    • Look, A.T.1
  • 2
  • 3
    • 2342591455 scopus 로고    scopus 로고
    • The discovery of receptor tyrosine kinases: Targets for cancer therapy
    • Gschwind A, Fischer OM, Ullrich A. The discovery of receptor tyrosine kinases: targets for cancer therapy. Nat Rev Cancer. 2004;4(5):361-370. (Pubitemid 38579482)
    • (2004) Nature Reviews Cancer , vol.4 , Issue.5 , pp. 361-370
    • Gschwind, A.1    Fischer, O.M.2    Ullrich, A.3
  • 5
    • 0028198206 scopus 로고
    • Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma
    • published erratum appears in Science. 1995;;267(5196):316-317
    • Morris SW, Kirstein MN, Valentine MB, et al. Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma [published erratum appears in Science. 1995;;267(5196):316-317]. Science. 1994;263(5196):1281-1284.
    • (1994) Science , vol.263 , Issue.5196 , pp. 1281-1284
    • Morris, S.W.1    Kirstein, M.N.2    Valentine, M.B.3
  • 6
    • 0028275645 scopus 로고
    • Hyperphosphorylation of a novel 80 kDa protein-tyrosine kinase similar to Ltk in a human Ki-1 lymphoma cell line, AMS3
    • Shiota M, Fujimoto J, Semba T, Satoh H, Yamamoto T, Mori S. Hyperphosphorylation of a novel 80 kDa protein-tyrosine kinase similar to Ltk in a human Ki-1 lymphoma cell line, AMS3. Oncogene. 1994;9(6):1567-1574. (Pubitemid 24163381)
    • (1994) Oncogene , vol.9 , Issue.6 , pp. 1567-1574
    • Shiota, M.1    Fujimoto, J.2    Semba, T.3    Satoh, H.4    Yamamoto, T.5    Mori, S.6
  • 7
    • 0031008896 scopus 로고    scopus 로고
    • ALK the chromosome 2 gene locus altered by the t(2;5) in non-Hodgkin's lymphoma, encodes a novel neural receptor tyrosine kinase that is highly related to leukocyte tyrosine kinase (LTK)
    • Morris SW, Naeve C, Mathew P, et al. ALK, the chromosome 2 gene locus altered by the t(2;5) in non-Hodgkin's lymphoma, encodes a novel neural receptor tyrosine kinase that is highly related to leukocyte tyrosine kinase (LTK). Oncogene. 1997;14(23):2175-2188. (Pubitemid 27248229)
    • (1997) Oncogene , vol.14 , Issue.18 , pp. 2175-2188
    • Morris, S.W.1    Naeve, C.2    Mathew, P.3    James, P.L.4    Kirstein, M.N.5    Cui, X.6    Witte, D.P.7
  • 8
    • 0030878811 scopus 로고    scopus 로고
    • Anaplastic large cell lymphomas expressing the novel chimeric protein p80NPM/ALK: A distinct clinicopathologic entity
    • Shiota M, Mori S. Anaplastic large cell lymphomas expressing the novel chimeric protein p80NPM/ALK: a distinct clinicopathologic entity. Leukemia. 1997;11(suppl 3):538-540. (Pubitemid 27313594)
    • (1997) Leukemia , vol.11 , Issue.SUPPL. 3 , pp. 538-540
    • Shiota, M.1    Mori, S.2
  • 10
    • 85047699293 scopus 로고    scopus 로고
    • Anaplastic lymphoma kinase (ALK) activates Stat3 and protects hematopoietic cells from cell death
    • DOI 10.1038/sj/onc/1205152
    • Zamo A, Chiarle R, Piva R, et al. Anaplastic lymphoma kinase (ALK) activates Stat3 and protects hematopoietic cells from cell death. Oncogene. 2002;21(7):1038-1047. (Pubitemid 34174516)
    • (2002) Oncogene , vol.21 , Issue.7 , pp. 1038-1047
    • Zamo, A.1    Chiarle, R.2    Piva, R.3    Howes, J.4    Fan, Y.5    Chilosi, M.6    Levy, D.E.7    Inghirami, G.8
  • 11
    • 0037384714 scopus 로고    scopus 로고
    • Constitutive activation of Jak2 contributes to proliferation and resistance to apoptosis in NPM/ALK-transformed cells
    • DOI 10.1016/S0301-472X(03)00007-9
    • Ruchatz H, Coluccia AM, Stano P, Marchesi E, Gambacorti-Passerini C. Constitutive activation of Jak2 contributes to proliferation and resistance to apoptosis in NPM/ALK-transformed cells. Exp Hematol. 2003;31(4):309-315. (Pubitemid 36407607)
    • (2003) Experimental Hematology , vol.31 , Issue.4 , pp. 309-315
    • Ruchatz, H.1    Coluccia, A.M.L.2    Stano, P.3    Marchesi, E.4    Gambacorti-Passerini, C.5
  • 12
    • 0032875697 scopus 로고    scopus 로고
    • Quantitative analysis of complex protein mixtures using isotope-coded affinity tags
    • DOI 10.1038/13690
    • Gygi SP, Rist B, Gerber SA, Turecek F, Gelb MH, Aebersold R. Quantitative analysis of complex protein mixtures using isotope-coded affinity tags. Nat Biotechnol. 1999;17(10):994-999. (Pubitemid 29474856)
    • (1999) Nature Biotechnology , vol.17 , Issue.10 , pp. 994-999
    • Gygi, S.P.1    Rist, B.2    Gerber, S.A.3    Turecek, F.4    Gelb, M.H.5    Aebersold, R.6
  • 13
    • 0347334566 scopus 로고    scopus 로고
    • Mass spectrometric analysis of protein mixtures at low levels using cleavable 13C-isotope-coded affinity tag and multidimensional chromatography
    • Hansen KC, Schmitt-Ulms G, Chalkley RJ, Hirsch J, Baldwin MA, Burlingame AL. Mass spectrometric analysis of protein mixtures at low levels using cleavable 13C-isotope-coded affinity tag and multidimensional chromatography. Mol Cell Proteomics. 2003;2(5):299-314.
    • (2003) Mol Cell Proteomics , vol.2 , Issue.5 , pp. 299-314
    • Hansen, K.C.1    Schmitt-Ulms, G.2    Chalkley, R.J.3    Hirsch, J.4    Baldwin, M.A.5    Burlingame, A.L.6
  • 14
    • 2342516776 scopus 로고    scopus 로고
    • Identification of NPM-ALK interacting proteins by tandem mass spectrometry
    • DOI 10.1038/sj.onc.1207398
    • Crockett DK, Lin Z, Elenitoba-Johnson KS, Lim MS. Identification of NPM-ALK interacting proteins by tandem mass spectrometry. Oncogene. 2004;23(15):2617-2629. (Pubitemid 38586315)
    • (2004) Oncogene , vol.23 , Issue.15 , pp. 2617-2629
    • Crockett, D.K.1    Lin, Z.2    Elenitoba-Johnson, K.S.J.3    Lim, M.S.4
  • 15
    • 1142287423 scopus 로고    scopus 로고
    • Utility of linearly amplified RNA for RT-PCR detection of chromosomal translocations: Validation using the t(2;5)(p23;q35) NPMALK chromosomal translocation
    • Schumacher JA, Jenson SD, Elenitoba-Johnson KS, Lim MS. Utility of linearly amplified RNA for RT-PCR detection of chromosomal translocations: validation using the t(2;5)(p23;q35) NPMALK chromosomal translocation. J Mol Diagn. 2004;6(1):16-21.
    • (2004) J Mol Diagn , vol.6 , Issue.1 , pp. 16-21
    • Schumacher, J.A.1    Jenson, S.D.2    Elenitoba-Johnson, K.S.3    Lim, M.S.4
  • 16
    • 4444243475 scopus 로고    scopus 로고
    • Quantitative proteomic and transcriptional analysis of the response to the p38 mitogen-activated protein kinase inhibitor SB203580 in transformed follicular lymphoma cells
    • DOI 10.1074/mcp.M400008-MCP200
    • Lin Z, Crockett DK, Jenson SD, Lim MS, Elenitoba-Johnson KS. Quantitative proteomic and transcriptional analysis of the response to the p38 mitogen-activated protein kinase inhibitor SB203580 in transformed follicular lymphoma cells. Mol Cell Proteomics. 2004;3(8):820-833. (Pubitemid 39199582)
    • (2004) Molecular and Cellular Proteomics , vol.3 , Issue.8 , pp. 820-833
    • Lin, Z.1    Crockett, D.K.2    Jenson, S.D.3    Lim, M.S.4    Elenitoba-Johnson, K.S.J.5
  • 17
    • 0034789979 scopus 로고    scopus 로고
    • Quantitative profiling of differentiation-induced microsomal proteins using isotope-coded affinity tags and mass spectrometry
    • DOI 10.1038/nbt1001-946
    • Han DK, Eng J, Zhou H, Aebersold R. Quantitative profiling of differentiation-induced microsomal proteins using isotope-coded affinity tags and mass spectrometry. Nat Biotechnol. 2001;19(10):946-951. (Pubitemid 32947573)
    • (2001) Nature Biotechnology , vol.19 , Issue.10 , pp. 946-951
    • Han, D.K.1    Eng, J.2    Zhou, H.3    Aebersold, R.4
  • 18
    • 26844452982 scopus 로고    scopus 로고
    • Revised draft guidelines for proteomic data publication
    • Bradshaw RA. Revised draft guidelines for proteomic data publication. Mol Cell Proteomics. 2005;4(9):1223-1225. (Pubitemid 41448710)
    • (2005) Molecular and Cellular Proteomics , vol.4 , Issue.9 , pp. 1223-1225
  • 19
    • 0037108299 scopus 로고    scopus 로고
    • Expression of Skp2, a p27(Kip1) ubiquitin ligase, in malignant lymphoma: Correlation with p27(Kip1) and proliferation index
    • Lim MS, Adamson A, Lin Z, et al. Expression of Skp2, a p27(Kip1) ubiquitin ligase, in malignant lymphoma: correlation with p27(Kip1) and proliferation index. Blood. 2002;100(8):2950-2956.
    • (2002) Blood , vol.100 , Issue.8 , pp. 2950-2956
    • Lim, M.S.1    Adamson, A.2    Lin, Z.3
  • 20
    • 0038175144 scopus 로고    scopus 로고
    • GoMiner: A resource for biological interpretation of genomic and proteomic data
    • Zeeberg BR, Feng W, Wang G, et al. GoMiner: a resource for biological interpretation of genomic and proteomic data. Genome Biol. 2003;4(4):R28.
    • (2003) Genome Biol , vol.4 , Issue.4
    • Zeeberg, B.R.1    Feng, W.2    Wang, G.3
  • 21
    • 0034069495 scopus 로고    scopus 로고
    • Gene ontology: Tool for the unification of biology: The Gene Ontology Consortium
    • Ashburner M, Ball CA, Blake JA, et al. Gene ontology: tool for the unification of biology: The Gene Ontology Consortium. Nat Genet. 2000;25(1):25-29.
    • (2000) Nat Genet , vol.25 , Issue.1 , pp. 25-29
    • Ashburner, M.1    Ball, C.A.2    Blake, J.A.3
  • 22
    • 0034672140 scopus 로고    scopus 로고
    • Nucleophosmin-anaplastic lymphoma kinase associated with anaplastic large-cell lymphoma activates the phosphatidylinositol 3-kinase/Akt antiapoptotic signaling pathway
    • Bai RY, Ouyang T, Miething C, Morris SW, Peschel C, Duyster J. Nucleophosmin-anaplastic lymphoma kinase associated with anaplastic large-cell lymphoma activates the phosphatidylinositol 3-kinase/Akt antiapoptotic signaling pathway. Blood. 2000;96(13):4319-4327.
    • (2000) Blood , vol.96 , Issue.13 , pp. 4319-4327
    • Bai, R.Y.1    Ouyang, T.2    Miething, C.3    Morris, S.W.4    Peschel, C.5    Duyster, J.6
  • 24
    • 2342635959 scopus 로고    scopus 로고
    • Anaplastic Lymphoma Kinase Proteins in Growth Control and Cancer
    • DOI 10.1002/jcp.10472
    • Pulford K, Morris SW, Turturro F. Anaplastic lymphoma kinase proteins in growth control and cancer. J Cell Physiol. 2004;199(3):330-358. (Pubitemid 38580430)
    • (2004) Journal of Cellular Physiology , vol.199 , Issue.3 , pp. 330-358
    • Pulford, K.1    Morris, S.W.2    Turturro, F.3
  • 25
    • 0345826110 scopus 로고    scopus 로고
    • RhoA Binds to the Amino Terminus of MEKK1 and Regulates Its Kinase Activity
    • DOI 10.1074/jbc.M309525200
    • Gallagher ED, Gutowski S, Sternweis PC, Cobb MH. RhoA binds to the amino terminus of MEKK1 and regulates its kinase activity. J Biol Chem. 2004;279(3):1872-1877. (Pubitemid 38084456)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.3 , pp. 1872-1877
    • Gallagher, E.D.1    Gutowski, S.2    Sternweis, P.C.3    Cobb, M.H.4
  • 26
    • 2442474029 scopus 로고    scopus 로고
    • G Protein-coupled receptors and their signaling pathways: Classical therapeutical targets susceptible to novel therapeutic concepts
    • DOI 10.2174/1381612043384367
    • Liebmann C. G protein-coupled receptors and their signaling pathways: classical therapeutical targets susceptible to novel therapeutic concepts. Curr Pharm Des. 2004;10(16):1937-1958. (Pubitemid 38647579)
    • (2004) Current Pharmaceutical Design , vol.10 , Issue.16 , pp. 1937-1958
    • Liebmann, C.1
  • 27
    • 0038236715 scopus 로고    scopus 로고
    • Integrins in regulation of tissue development and function
    • Danen EH, Sonnenberg A. Integrins in regulation of tissue development and function. J Pathol. 2003;200(4):471-480.
    • (2003) J Pathol , vol.200 , Issue.4 , pp. 471-480
    • Danen, E.H.1    Sonnenberg, A.2
  • 28
    • 0032999830 scopus 로고    scopus 로고
    • Target of rapamycin (TOR): Balancing the opposing forces of protein synthesis and degradation
    • Dennis PB, Fumagalli S, Thomas G. Target of rapamycin (TOR): balancing the opposing forces of protein synthesis and degradation. Curr Opin Genet Dev. 1999;9(1):49-54.
    • (1999) Curr Opin Genet Dev , vol.9 , Issue.1 , pp. 49-54
    • Dennis, P.B.1    Fumagalli, S.2    Thomas, G.3
  • 29
    • 0030915898 scopus 로고    scopus 로고
    • Rapamycin suppresses 5'TOP mRNA translation through inhibition of p70(s6k)
    • DOI 10.1093/emboj/16.12.3693
    • Jefferies HB, Fumagalli S, Dennis PB, Reinhard C, Pearson RB, Thomas G. Rapamycin suppresses 5′ TOP mRNA translation through inhibition of p70s6k. EMBO J. 1997;16(12):3693-3704. (Pubitemid 27250062)
    • (1997) EMBO Journal , vol.16 , Issue.12 , pp. 3693-3704
    • Jefferies, H.B.J.1    Fumagalli, S.2    Dennis, P.B.3    Reinhard, C.4    Pearson, R.B.5    Thomas, G.6
  • 32
    • 30444446194 scopus 로고    scopus 로고
    • Ablation of oncogenic ALK is a viable therapeutic approach for anaplastic large cell lymphomas
    • Piva R, Chiarle R, Manazza A, et al. Ablation of oncogenic ALK is a viable therapeutic approach for anaplastic large cell lymphomas. Blood. 2006;107(2):689-697.
    • (2006) Blood , vol.107 , Issue.2 , pp. 689-697
    • Piva, R.1    Chiarle, R.2    Manazza, A.3
  • 34
    • 3042819506 scopus 로고    scopus 로고
    • The RET receptor is linked to stress response pathways
    • DOI 10.1158/0008-5472.CAN-03-3605
    • Myers SM, Mulligan LM. The RET receptor is linked to stress response pathways. Cancer Res. 2004;64(13):4453-4463. (Pubitemid 38856916)
    • (2004) Cancer Research , vol.64 , Issue.13 , pp. 4453-4463
    • Myers, S.M.1    Mulligan, L.M.2
  • 37
    • 33746118057 scopus 로고    scopus 로고
    • Activation of mammalian target of rapamycin signaling pathway contributes to tumor cell survival in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma
    • DOI 10.1158/0008-5472.CAN-05-3018
    • Vega F, Medeiros LJ, Leventaki V, et al. Activation of mammalian target of rapamycin signaling pathway contributes to tumor cell survival in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma. Cancer Res. 2006;66(13):6589-6597. (Pubitemid 44085614)
    • (2006) Cancer Research , vol.66 , Issue.13 , pp. 6589-6597
    • Vega, F.1    Medeiros, L.J.2    Leventaki, V.3    Atwell, C.4    Cho-Vega, J.H.5    Tian, L.6    Claret, F.-X.7    Rassidakis, G.Z.8
  • 39
    • 33846951463 scopus 로고    scopus 로고
    • Oncogenic tyrosine kinase NPM/ALK induces activation of the MEK/ERK signaling pathway independently of c-Raf
    • DOI 10.1038/sj.onc.1209843, PII 1209843
    • Marzec M, Kasprzycka M, Liu X, Raghunath PN, Wlodarski P, Wasik MA. Oncogenic tyrosine kinase NPM/ALK induces activation of the MEK/ERK signaling pathway independently of c-Raf. Oncogene. 2007;26(6):813-821. (Pubitemid 46245735)
    • (2007) Oncogene , vol.26 , Issue.6 , pp. 813-821
    • Marzec, M.1    Kasprzycka, M.2    Liu, X.3    Raghunath, P.N.4    Wlodarski, P.5    Wasik, M.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.