Cell-type-specific expression of neural cell adhesion molecule (N-CAM) in Ito cells of rat liver: Up-regulation during in vitro activation and in hepatic tissue repair

American Journal of Pathology

Volumn 149, Issue 2, 1996, Pages 449-462

  Knittel, Thomas ^a   Aurisch, Sabine ^a   Neubauer, Katrin ^a   Eichhorst, Sören ^a   Ramadori, Giuliano ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GLIAL FIBRILLARY ACIDIC PROTEIN; NERVE CELL ADHESION MOLECULE;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; GENE INDUCTION; ITO CELL; LIVER INJURY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ACTINS; ANIMALS; BASE SEQUENCE; BIOLOGICAL MARKERS; CELL ADHESION MOLECULES, NEURONAL; CELLS, CULTURED; DNA PRIMERS; GENE EXPRESSION REGULATION; GLIAL FIBRILLARY ACIDIC PROTEIN; LIVER; LIVER DISEASES; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; RATS; RATS, WISTAR; RNA-DIRECTED DNA POLYMERASE; TRANSFORMING GROWTH FACTOR BETA; UP-REGULATION;

EID: 0030056244     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (59)

1. Cunningham B: Cell adhesion molecules as morphoregulators. Curr Opin Cell Biol 1995, 7:628-633
2. Edelman G, Crossin K: Cell adhesion molecules: implication for a molecular histology. Annu Rev Biochem 1991, 60:155-190
3. Cole GJ, Akeson R: Identification of a heparin binding domain of the neural cell adhesion molecule N-CAM using synthetic peptides. Neuron 1989, 2:1157-1165
4. Kallapur SG, Akeson RA: The neural cell adhesion molecule (NCAM) heparin binding domain binds to cell surface heparan sulfate proteoglycans. J Neurosci Res 1992, 33:538-548
5. Friedlander DR, Milev P, Karthikeyan L, Margolis RK, Margolis RU, Grumet M: The neuronal chondroitin sulfate proteoglycan neurocan binds to the neural cell adhesion molecules Ng-CAM/L1/NILE and N-CAM and inhibits neuronal adhesion and neurite outgrowth. J Cell Biol 1994, 125:669-680
6. Milev P, Friedlander DR, Sakurai T, Karthikeyan L, Flad M, Margolis RK, Grumet M, Margolis RU: Interactions of the chondroitin sulfate proteoglycan phosphacan, the extracellular domain of a receptor-type protein tyrosine phosphatase, with neurons, glia, and neural cell adhesion molecules. J Cell Biol 1994, 127:1703-1715
7. Reyes AA, Small SJ, Akeson R: At least 27 alternatively spliced forms of the neural cell adhesion molecule mRNA are expressed during rat heart development. Mol Cell Biol 1991, 11:1654-1661
8. Eckhardt M, Muhlenhoff M, Bethe A, Koopman J, Frosch M, Gerardy SR: Molecular characterization of eukaryotic polysialyltransferase-1. Nature 1995, 373:715-718
9. Frei T, von Bu HF, Wille W, Schachner M: Different extracellular domains of the neural cell adhesion molecule (N-CAM) are involved in different functions. J Cell Biol 1992, 118:177-194
10. Sunshine J, Balak K, Rutishauser U, Jacobson M: Changes in neural cell adhesion molecule (NCAM) structure during vertebrate neural development. Proc Natl Acad Sci USA 1987, 84:5986-5990
11. Moller CJ, Christgau S, Williamson MR, Madsen OD, Niu ZP, Bock E, Baekkeskov S: Differential expression of neural cell adhesion molecule and cadherins in pancreatic islets, glucagonomas, and insulinomas. Mol Endocrinol 1992, 6:1332-1342
12. Mizutani H, Roswit W, Hemperly J, Lawley T, Compton C, Swerlick R, Kupper TS: Human dermal microvascular endothelial cells express the 140-kD isoform of neural cell adhesion molecule. Biochem Biophys Res Commun 1994, 203:686-693
13. Tavella S, Raffo P, Tacchetti C, Cancedda R, Castagnola P: N-CAM, and N-cadherin expression during in vitro chondrogenesis. Exp Cell Res 1994, 215:354-362
14. Roubin R, Deagostini BH, Hirsch MR, Goridis C: Modulation of NCAM expression by transforming growth factor-β, serum, and autocrine factors. J Cell Biol 1990, 111:673-684
15. Gulbenkian S, Santos J, Gordon L, Wharton J, Polak JM, David FJ: Neural cell adhesion molecule is expressed by smooth muscle cells during the development of the rat vascular system. J Neurocytol 1989, 18:809-817
16. Nouwen EJ, Dauwe S, van der Biest I, De Broe ME: Stage- and segment-specific expression of cell-adhesion molecules N-CAM, A-CAM, and L-CAM in the kidney. Kidney Int 1993, 44:147-158
17. Lanier LL, Testi R, Bindl J, Phillips JH: Identity of Leu-19 (CD56) leukocyte differentiation antigen and neural cell adhesion molecule. J Exp Med 1989, 169:2233-2238
18. Moolenaar CE, Pieneman C, Walsh FS, Mooi WJ, Michalides RJ: Alternative splicing of neural-cell-adhesion molecule mRNA in human small-cell lung-cancer cell line H69. Int J Cancer 1992, 51:238-243
19. Dickson G, Peck D, Moore SE, Barton CH, Walsh FS: Enhanced myogenesis in NCAM-transfected mouse myoblasts. Nature 1990, 344:348-351
20. Krushel LA, Sporns O, Cunningham BA, Crossin KL, Edelman GM: Neural cell adhesion molecule (N-CAM) inhibits astrocyte proliferation after injury to different regions of the adult rat brain. Proc Natl Acad Sci USA 1995, 92:4323-4327
21. Smith DV, Klevitsky R, Akeson RA, Shipley MT: Expression of the neural cell adhesion molecule (NCAM) and polysialic acid during taste bud degeneration and regeneration. J Comp Neurol 1994, 347:187-196
22. Chuong CM, Chen HM: Enhanced expression of neural cell adhesion molecules and tenascin (cytotactin) during wound healing. Am J Pathol 1991, 138:427-440
23. Zocchi MR, Ferrero E, Toninelli E, Castellani P, Poggi A, Rugarli C: Expression of N-CAM by human renal cell carcinomas correlates with growth rate and adhesive properties. Exp Cell Res 1994, 214:499-509
24. Ramadori G, Rieder H, Knittel T: Biology and Pathobiology of Sinusoidal Liver Cells. Edited by N Tavoloni, P Berk P. New York, Raven Press, 1993, pp 83-102
25. Knittel T, Ramadori G: Current concepts of liver fibrosis. Forum Trends Exp Clin Med 1994, 4:236-257
26. Ramadori G: The stellate cell (Ito-cell, fat-storing cell, lipocyte, perisinusoidal cell) of the liver: new insights into pathophysiology of an intriguing cell. Virchows Arch B 1991, 61:147-158
27. Pinzani M: Novel insights into the biology and physiology of the Ito cell. Pharmacol Ther 1995, 66:387-412
28. Tsutsumi M, Takada A, Takase S: Characterization of desmin-positive rat liver sinusoidal cells Hepatology 1987, 7:277-284
29. Ramadori G, Veit T, Schwögler S, Dienes HP, Knittel T, Rieder H, Meyer zum Büschenfelde K-H: Expression of the gene of the α-smooth muscle actin isoform in rat liver and in rat fat-storing (Ito) cells. Virchows Arch B 1990, 59:349-357
30. Neubauer K, Knittel T, Aurisch S, Fellmer P, Ramadori G: GFAP allows identification of Ito cells in normal and damaged rat livers and in culture. J Hepatol 1996 (in press)
31. Dijkstra CD, Döpp EA, Joling P, Kraal G: The heterogeneity of mononuclear phagocytes in lymphoid organs: distinct macrophage subpopulations in the rat recognized by monoclonal antibodies ED1, ED2, and ED3. Immunology 1985, 54:589-599
32. Schwartz RJ, Haron JA, Rothblum KM, Dugaiczyk A: Regulation of muscle differentiation: cloning of sequences from α-actin messenger ribonucleic acid. Biochemistry 1980, 19:5883-5890
33. McHugh KM, Lessard JL: The nucleotide sequence of a rat vascular smooth muscle α-actin cDNA. Nucleic Acids Res 1988, 16:4167-4167
34. Chen W-J, Liem RKH: Reexpression of glial fibrillary acidic protein rescues the ability of astrocytoma cells to form processes in response to neurons. J Cell Biol 1994, 127:813-823
35. Barbu V, Dautry F: Northern blot normalization with a 28S rRNA oligonucleotide probe Nucleic Acids Res 1989, 17:7115
36. Small SJ, Shull GE, Santoni MJ, Akeson R: Identification of a cDNA clone that contains the complete coding sequence for a 140-kD rat NCAM polypeptide. J Cell Biol 1987, 105:2335-2345
37. Arcari P, Martinelli R, Salvatore F: The complete sequence of a full length cDNA for human liver glyceraldehyde-3-phosphate dehydrogenase: evidence for multiple mRNA species. Nucleic Acids Res 1984, 12: 9179-9189
38. Knittel T, Armbrust T, Schwögler S, Schuppan D, Meyer zum Büschenfelde K-H, Ramadori G: Distribution and cellular origin of undulin in the rat liver. Lab Invest 1992, 67:779-787
39. Knittel T. Armbrust T, Neubauer K, Ramadori G: Expression of von Willebrand factor in normal and diseased rat livers and in cultivated liver cells. Hepatology 1995, 21:470-476
40. Knittel T, Schuppan D, Meyer zum Büschenfelde K-H, Ramadori G: Differential expression of collagen types I, III, and IV by fat-storing (Ito) cells in vitro. Gastroenterology 1992, 102:1724-1735
41. Neubauer K, Knittel T, Armbrust T, Ramadori G: Accumulation and cellular localisation of fibrinogen/fibrin during short term and long term rat liver injury. Gastroenterology 1995, 108:1124-1135
42. Ramadori G, Lenzi M, Dienes HP, Meyer zum Büschenfelde K-H: Binding properties of mechanically and enzymatically isolated hepatocytes for IgG and C3. Liver 1983, 3:358-368
43. Ramadori G, Rieder H, Knittel T, Dienes HP, Meyer zum Büschenfelde K-H: Fat storing cells (FSC) of rat liver synthesize and secrete fibronectin: comparison with hepatocytes. J Hepatol 1987, 4:190-197
44. Ramadori G, Schwogler S, Veit T, Rieder H, Chiquet ER, Mackie EJ, Meyer zum Büschenfelde K-H: Tenascin gene expression in rat liver and in rat liver cells: in vivo and in vitro studies. Virchows Arch B 1991, 60 145-153
45. Laemmli UK: Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970, 227:680-682
46. Towbin H, Staehelin T, Gordon J: Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA 1979, 76:4350-4354
47. Theveniau M, Guo XJ, Rage P, Rougon G: Removal of C6 astrocytoma cell surface molecules with phosphatidylinositol phospholipase C: effect on regulation of neural cell adhesion molecule isoforms. J Neurochem 1991, 57:67-74
48. Fantini J, Guo XJ, Marvaldi J, Rougon G: Suramin inhibits proliferation of rat glioma cells and alters N-CAM cell surface expression, Int J Cancer 1990, 45:554-561
49. Ramadori G, Knittel T, Odenthal M, Schwogler S, Neubauer K, Meyer zum Büschenfelde K-H: Synthesis of cellular fibronectin by rat liver fat-storing (Ito) cells: regulation by cytokines. Gastroenterology 1992, 103: 1313-1321
50. McCartney FN, Wahl SM: Transforming growth factor β: a matter of life and death. J Leukocyte Biol 1994, 55:401-409
51. Czaja MJ, Weiner FR, Flanders KC, Giambrone M-A, Wind R, Biempica L, Zern MA: In vitro and in vivo association of transforming growth factor-β1 with hepatic fibrosis. J Cell Biol 1989, 108:2477-2482
52. Nakatsukasa H, Nagy P, Evarts RP, Hsia CC, Marsden E, Thorgeirsson SS: Cellular distribution of transforming growth factor-β1 and procollagen types I, III, and IV transcripts in carbon tetrachloride-induced rat liver fibrosis J Clin Invest 1990, 85:1833-1843
53. Milani S, Herbst H, Schuppan D, Stein H, Surrenti C: Transforming growth factors β1 and β2 are differentially expressed in fibrotic liver disease. Am J Pathol 1991, 139:1221-1229
54. Scoazec JY, Racine L, Couvelard A, Moreau A, Flejou JF, Bernuau D, Feldmann G: Parenchymal innervation of normal and cirrhotic human liver: a light and electron microscopic study using monoclonal antibodies against the neural cell-adhesion molecule. J Histochem Cytochem 1993, 41:899-908
55. Roskams T, van den Oord JJ, De Vos R, Desmet VJ: Neuroendocrine features of reactive bile ductules in cholestatic liver disease. Am J Pathol 1990, 137:1019-1025
56. Volpes R, van den Oord JJ, Desmet VJ: Integrins as differential cell lineage markers of primary liver tumors. Am J Pathol 1993, 142:1483-1492
57. Sporns O, Edelman GM, Crossin KL: The neural cell adhesion molecule (N-CAM) inhibits proliferation in primary cultures of rat astrocytes. Proc Natl Acad Sci USA 1995, 92:542-546
58. Knittel T, Ramadori G: Molecular biology. Curr Opin Gastroenterol 1995, 11:258-266
59. Devereux J, Haeberli P, Smithies O: A comprehensive set of sequence analysis programs for the VAX, Nucleic Acids Res 1984, 12:387-395