Differential regulation of inducible nitric oxide synthase and cyclooxygenase-2 expression by superoxide dismutase in lipopolysaccharide stimulated RAW 264.7 cells

Experimental and Molecular Medicine

Volumn 41, Issue 9, 2009, Pages 629-637

  Ji, Ae Lee ^a   Ha, Yong Song ^a   Sung, Mi Ju ^a   Su, Jin Lee ^a   Kwon, Hyung Joo ^a   Won, Sik Eum ^a   Sang, Ho Jang ^a   Choi, Soo Young ^a   Park, Jinseu ^a  

^a Hallym University   (South Korea)

Author keywords

Cyclooxygenase 2; Lipopolysaccharides; NF B; Nitric oxide synthase type II; Reactive oxygen species; Superoxide dismutase

Indexed keywords

CYCLOOXYGENASE 2; DNA; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE; PROSTAGLANDIN E2; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL LINE; CELL STRAIN RAW 264.7; CULTURE MEDIUM; CYTOKINE PRODUCTION; MOUSE; NONHUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION;

EID: 70349467874     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.3858/emm.2009.41.9.069     Document Type: Article

References (24)

1. Chun KS, Surh YJ. Signal transduction pathways regulating cyclooxygenase-2 expression: potential molecular targets for chemoprevention. Biochem Pharmacol 2004;68:1089-1100
2. Eum WS, Choung IS, Li MZ, Kang JH, Kim DW, Park J, Kwon HY, Choi SY. HIV-1 Tat-mediated protein transduction of Cu,Zn-superoxide dismutase into pancreatic beta cells in vitro and in vivo. Free Radic Biol Med 2004;37:339-349 (Pubitemid 38834000)
3. Flohe L, Brigelius-Flohe R, Saliou C, Traber MG, Packer L. Redox regulation of NF-kappa B activation. Free Radic Biol Med 1997;22:1115-1126
4. Gloire G, Legrand-Poels S, Piette J. NF-kappaB activation by reactive oxygen species: fifteen years later. Biochem Pharmacol 2006;72:1493-1505 (Pubitemid 44666727)
5. Guha M, Mackman N. LPS induction of gene expression in human monocytes. Cell Signal 2001;13:85-94 (Pubitemid 32222977)
6. Halliwell B, Gutteridge JM. Role of free radicals and catalytic metal ions in human disease: an overview. Methods Enzymol 1990;186:1-85 (Pubitemid 20279941)
7. Jaiswal AK. Nrf2 signaling in coordinated activation of antioxidant gene expression. Free Radic Biol Med 2004;36:1199-1207
8. Kabe Y, Ando K, Hirao S, Yoshida M, Handa H. Redox regulation of NF-κB activation: distinct redox regulation between the cytoplasm and the nucleus, Antioxidants and Redox Signaling 2005;7:395-403 (Pubitemid 40279807)
9. Keller JN, Hanni KB, Gabbita SP, Friebe V, Mattson MP, Kindy MS. Oxidized lipoproteins increase reactive oxygen species formation in microglia and astrocyte cell lines. Brain Res 1999;830:10-15 (Pubitemid 29251707)
10. Kleinert H, Pautz A, Linker K, Schwarz PM. Regulation of the expression of inducible nitric oxide synthase. Eur J Pharmacol 2004;500:255-266 (Pubitemid 39304013)
11. Kwon HY, Eum WS, Jang HW, Kang JH, Ryu J, Lee BR, Ryoung LB, Jin LH, Park J, Choi SY.. Transduction of Cu,Zn-superoxide dismutase mediated by an HIV-1 Tat protein basic domain into mammalian cells. FEBS Lett 2000;485:163-167 (Pubitemid 30950530)
12. Kyaw M, Yoshizumi M, Tsuchiya K, Izawa Y, Kanematsu Y, Tamaki T. Atheroprotective effects of antioxidants through inhibition of mitogen-activated protein kinases. Acta Pharmacol Sin 2004;25:977-985 (Pubitemid 39071099)
13. Mates JM. Effects of antioxidant enzymes in the molecular control of reactive oxygen species toxicology. Toxicology 2000;153:83-104 (Pubitemid 30945576)
14. Park HS, Jung HY, Park EY, Kim J, Lee WJ, Bae YS. Cutting edge: direct interaction of TLR4 with NAD(P)H oxidase 4 isozyme is essential for lipopolysaccharide-induced production of reactive oxygen species and activation of NF-kappa B. J Immunol 2004;173:3589-3593 (Pubitemid 39280716)
15. Sanlioglu S, Williams CM, Samavati L, Butler NS, Wang G, McCray PB Jr, Ritchie TC, Hunninghake GW, Zandi E, Engelhardt JF. Lipopolysaccharide induces Rac1-dependent reactive oxygen species formation and coordinates tumor necrosis factor-alpha secretion through IKK regulation of NF-kappa B. J Biol Chem 2001;276:30188-30198 (Pubitemid 37385100)
16. Schulze-Osthoff K, Bauer MK, Vogt M, Wesselborg S. Oxidative stress and signal transduction. Int J Vitam Nutr Res 1997;67:336-342
17. Schwarze, SR, Ho A, Vocero-Akbani A, Dowdy SF. In vivo protein transduction: delivery of a biologically active protein into the mouse. Science 1999;285:1569-1572
18. Schwarze, SR, Dowdy SF. In vivo protein transduction: intracellular delivery of biologically active proteins, compounds and DNA. Trends Pharmacol. Sci 2000;21:45-48
19. Sen CK, Packer L. Antioxidant and redox regulation of gene transcription. FASEB J 1996;10:709-720 (Pubitemid 26172817)
20. Song HY, Ju SM, Lee JA, Kwon HJ, Eum WS, Jang SH, Choi SY, Park J. Suppression of HIV-1 Tat-induced monocyte adhesiveness by a cell-permeable superoxide dismutase in astrocytes. Exp Mol Med 2007;39:778-786
21. Song HY, Lee JA, Ju SM, Yoo KY, Won MH, Kwon HJ, Eum WS, Jang SH, Choi SY, Park J. Topical transduction of superoxide dismutase mediated by HIV-1 Tat protein transduction domain ameliorates 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice. Biochem. Pharmacol 2008;75:1348-1357
22. Surh YJ, Kundu JK, Na HK, Lee JS. Redox-sensitive transcription factors as prime targets for chemoprevention with anti-inflammatory and antioxidative phytochemicals. J Nutr 2005;135(12 Suppl):2993S-3001S.
23. Wang H, Joseph JA. Quantifying cellular oxidative stress by dichlorofluorescein assay using microplate reader. Free Radic Biol Med 1999;27:612-616 (Pubitemid 29408648)
24. Zafarullah M, Li WQ, Sylvester J, Ahmad M. Molecular mechanisms of N-acetylcysteine actions. Cell Mol Life Sci 2003;60:6-20