CKIε/δ-dependent phosphorylation is a temperature-insensitive, period-determining process in the mammalian circadian clock

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 37, 2009, Pages 15744-15749

  Isojima, Yasushi ^a,b   Nakajima, Masato ^b   Ukai, Hideki ^b   Fujishima, Hiroshi ^b   Yamada, Rikuhiro G ^b   Masumoto, Koh Hei ^b   Kiuchi, Reiko ^a,b   Ishida, Mayumi ^b   Ukai Tadenuma, Maki ^b   Minami, Yoichi ^b   Kito, Ryotaku ^b   Nakao, Kazuki ^b   Kishimoto, Wataru ^b   Yoo, Seung Hee ^c,d   Shimomura, Kazuhiro ^c   Takao, Toshifumi ^e   Takano, Atsuko ^e   Kojima, Toshio ^a   Nagai, Katsuya ^e   Sakaki, Yoshiyuki ^a   Takahashi, Joseph S ^c,d   Ueda, Hiroki R ^b,e   more..

^a RIKEN YOKOHAMA INSTITUTE   (Japan)

^b RIKEN   (Japan)

^c NORTHWESTERN UNIVERSITY   (United States)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^e OSAKA UNIVERSITY   (Japan)

Author keywords

Chemical biological approach; Temperature compensation

Indexed keywords

CASEIN KINASE IDELTA; CASEIN KINASE IEPSILON; PER2 PROTEIN; SYNTHETIC PEPTIDE; CELL CYCLE PROTEIN; NUCLEAR PROTEIN; PER2 PROTEIN, MOUSE; PROTEIN KINASE INHIBITOR; RECOMBINANT PROTEIN; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; CELL STRAIN 3T3; CIRCADIAN RHYTHM; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HEAT SENSITIVITY; HUMAN; HUMAN CELL; IN VITRO STUDY; MAMMAL; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; ANIMAL; BIOLOGICAL MODEL; CELL LINE; CYANOBACTERIUM; DRUG ANTAGONISM; DRUG EFFECT; EVOLUTION; GENETIC TRANSFECTION; GENETICS; KINETICS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; TEMPERATURE;

MAMMALIA;

ANIMALS; CASEIN KINASE IDELTA; CASEIN KINASE IEPSILON; CELL CYCLE PROTEINS; CELL LINE; CIRCADIAN RHYTHM; CYANOBACTERIA; EVOLUTION; HUMANS; KINETICS; MICE; MODELS, BIOLOGICAL; NIH 3T3 CELLS; NUCLEAR PROTEINS; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; RECOMBINANT PROTEINS; RNA, SMALL INTERFERING; TEMPERATURE; TRANSCRIPTION FACTORS; TRANSFECTION;

EID: 70349452319     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0908733106     Document Type: Article

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