-
1
-
-
0023130389
-
Haematological preclinical recording of adverse drug reactions - Current status, problems, and needs. Part II. Diagnostic aspects
-
Berger J. Haematological preclinical recording of adverse drug reactions - current status, problems, and needs. Part II. Diagnostic aspects. Folia Haematol 1987;114:16-41
-
(1987)
Folia Haematol
, vol.114
, pp. 16-41
-
-
Berger, J.1
-
2
-
-
0036977845
-
Haematotoxicology: Scientific basis and regulatory aspects
-
Gribaldo L. Haematotoxicology: scientific basis and regulatory aspects. ATLA 2002;30(Suppl. 2):111-113 (Pubitemid 36168722)
-
(2002)
ATLA Alternatives to Laboratory Animals
, vol.30
, Issue.SUPPL. 2
, pp. 111-113
-
-
Gribaldo, L.1
-
3
-
-
15844423731
-
Hematology tests in toxicology - Time for a re-think
-
Brown G. Hematology tests in toxicology - time for a re-think. Comp Haematol Int 1992;2:231-235
-
(1992)
Comp Haematol Int
, vol.2
, pp. 231-235
-
-
Brown, G.1
-
4
-
-
0027521852
-
Application of animal toxicology data to clinical study of experimental drugs
-
Tomaszewski KE. Application of animal toxicology data to clinical study of experimental drugs. Comp Haematol Int 1993;3:67-70
-
(1993)
Comp Haematol Int
, vol.3
, pp. 67-70
-
-
Tomaszewski, K.E.1
-
5
-
-
0033922324
-
Preclinical safety assessment: In vitro - In vivo testing
-
Hojelse F. Preclinical safety assessment: in vitro-in vivo testing. Pharmacol Toxicol 2000;86(Suppl. 1):6-7 (Pubitemid 30431999)
-
(2000)
Pharmacology and Toxicology, Supplement
, vol.86
, Issue.1
, pp. 6-7
-
-
Hojelse, F.1
-
6
-
-
0036188952
-
Quality review procedures necessary for rodent pathology databases and toxicogenomic studies: The national toxicology program experience
-
Boorman GA, Haseman JK, Waters MD, Hardisty JF, Sills RC. Quality review procedures necessary for rodent pathology databases and toxicogenomic studies: the national toxicology program experience. Toxicol Pathol 2002;30:88-92
-
(2002)
Toxicol Pathol
, vol.30
, pp. 88-92
-
-
Boorman, G.A.1
Haseman, J.K.2
Waters, M.D.3
Hardisty, J.F.4
Sills, R.C.5
-
7
-
-
0036852418
-
A new method to evaluate in vitro myelotoxicity of antitumour agents in the first steps of drug development
-
Kremers P. A new method to evaluate in vitro myelotoxicity of antitumour agents in the first steps of drug development. Pharmacol Toxicol 2002;91:209-217
-
(2002)
Pharmacol Toxicol
, vol.91
, pp. 209-217
-
-
Kremers, P.1
-
8
-
-
14744294346
-
Hematotoxicity testing by cell clonogenic assay in drug development and preclinical trials
-
DOI 10.2174/1381612053381648
-
Pessina A, Malerba I, Gribaldo L. Hematotoxicity testing by cell clonogenic assay in drug development and preclinical trials. Curr Pharm Design 2005;11:1055-1065 (Pubitemid 40331306)
-
(2005)
Current Pharmaceutical Design
, vol.11
, Issue.8
, pp. 1055-1065
-
-
Pessina, A.1
Malerba, I.2
Gribaldo, L.3
-
9
-
-
0027665355
-
Toxicity testing and genetic quality control
-
van Zutphen LF. Toxicity testing and genetic quality control. J Exp Anim Sci 1993;35:202-209
-
(1993)
J Exp Anim Sci
, vol.35
, pp. 202-209
-
-
Van Zutphen, L.F.1
-
11
-
-
3342921068
-
Why is it proving to be so difficult to replace animal tests?
-
Balls M. Why is it proving to be so difficult to replace animal tests? Lab Anim 1998;27:44-47
-
(1998)
Lab Anim
, vol.27
, pp. 44-47
-
-
Balls, M.1
-
12
-
-
0038717379
-
Alternative methods for acute oral toxicity testing: Practical guidance for implementation
-
Rispin A, McCall D, Farrar D, et al. Alternative methods for acute oral toxicity testing: practical guidance for implementation. Lab Anim 2002;31:42-48 (Pubitemid 36707304)
-
(2002)
Lab Animal
, vol.31
, Issue.7
, pp. 42-48
-
-
Rispin, A.1
McCall, D.2
Farrar, D.3
Margosches, E.4
Gupta, K.5
Stitzel, K.6
Carr, G.7
Greene, M.8
Rogers, J.9
Meyer, W.10
-
13
-
-
0031800079
-
Predicting hematological toxicity (myelosuppression) of cytotoxic drug therapy from in vitro tests
-
DOI 10.1023/A:1008245906772
-
Parchment RE, Gordon M, Grieshaber CK, Sessa C, Volpe D, Ghielmini M. Predicting hematological toxicity (myelosuppression) of cytotoxic drug therapy from in vitro tests. Ann Oncol 1998;9:357-364 (Pubitemid 28273026)
-
(1998)
Annals of Oncology
, vol.9
, Issue.4
, pp. 357-364
-
-
Parchment, R.E.1
Gordon, M.2
Grieshaber, C.K.3
Sessa, C.4
Volpe, D.5
Ghielmini, M.6
-
14
-
-
27744546180
-
Ensuring quality of in vitro alternative test methods: Issues and answers
-
DOI 10.1016/j.yrtph.2005.03.010, PII S0273230005000462
-
Gupta K, Rispin A, Stitzel K, Coecke S, Harbell J. Ensuring quality of in vitro alternative test methods: issues and answers. Regul Toxicol Pharmacol 2005;43:219-224 (Pubitemid 41616388)
-
(2005)
Regulatory Toxicology and Pharmacology
, vol.43
, Issue.3
, pp. 219-224
-
-
Gupta, K.1
Rispin, A.2
Stitzel, K.3
Coecke, S.4
Harbell, J.5
-
15
-
-
28944451562
-
Testing strategies in mutagenicity and genetic toxicology: An appraisal of the guidelines of the European Scientific Committee for Cosmetics and Non-Food Products for the evaluation of hair dyes
-
DOI 10.1016/j.mrgentox.2005.09.006, PII S1383571805002305
-
Kirkland DJ, Henderson L, Marzin D, et al. Testing strategies in mutagenicity and genetic toxicology: an appraisal of the guidelines of the European Scientific Committee for Cosmetics and Non-Food Products for the evaluation of hair dyes. Mutat Res - Gen Toxicol Environ Mutat 2005;588:88-105 (Pubitemid 41785731)
-
(2005)
Mutation Research - Genetic Toxicology and Environmental Mutagenesis
, vol.588
, Issue.2
, pp. 88-105
-
-
Kirkland, D.J.1
Henderson, L.2
Marzin, D.3
Muller, L.4
Parry, J.M.5
Speit, G.6
Tweats, D.J.7
Williams, G.M.8
-
16
-
-
0346336275
-
The Status of Laboratory Animal Production and Visions in the 21st Century
-
Gartner K. The status of laboratory animal production and visions in the 21st century. Asian-Aust J Anim Sci 1999;12:1142-1151 (Pubitemid 129602428)
-
(1999)
Asian-Australasian Journal of Animal Sciences
, vol.12
, Issue.7
, pp. 1142-1151
-
-
Gartner, K.1
-
17
-
-
0035165442
-
A new method to evaluate in vitro myelotoxicity of antitumour agents in the first steps of drug development
-
Scambia G. A new method to evaluate in vitro myelotoxicity of antitumour agents in the first steps of drug development. Pharmacol Toxicol 2001;89:231-236 (Pubitemid 33070923)
-
(2001)
Pharmacology and Toxicology
, vol.89
, Issue.5
, pp. 231-236
-
-
Scambia, G.1
-
18
-
-
0037280022
-
In vitro hematotoxicity testing in drug development: A review of past, present and future applications
-
Rich IN. In vitro hematotoxicity testing in drug development: a review of past, present and future applications. Curr Opin Drug Discov Dev 2003;6:100-109
-
(2003)
Curr Opin Drug Discov Dev
, vol.6
, pp. 100-109
-
-
Rich, I.N.1
-
19
-
-
0031804663
-
Invertebrates in testing of environmental chemicals: Are they alternatives?
-
Lagadic L, Caquet T. Invertebrates in testing of environmental chemicals: are they alternatives? Environ Health Perspect 1998;106:593-611
-
(1998)
Environ Health Perspect
, vol.106
, pp. 593-611
-
-
Lagadic, L.1
Caquet, T.2
-
20
-
-
0033888025
-
Acute toxicity test with Daphnia magna: An alternative to mammals in the prescreening of chemical toxicity?
-
Guilhermino L, Diamantino T, Silva MC, Soares AMVM. Acute toxicity test with Daphnia magna: an alternative to mammals in the prescreening of chemical toxicity? Ecotoxicol Environ Saf 2000;46:357-362
-
(2000)
Ecotoxicol Environ Saf
, vol.46
, pp. 357-362
-
-
Guilhermino, L.1
Diamantino, T.2
Silva, M.C.3
Amvm, S.4
-
21
-
-
0021226982
-
Somatic mutation and recombination test in Drosophila melanogaster
-
Graf U, Wurgler FE, Katz AJ. Somatic mutation and recombination test in Drosophila melanogaster. Environ Mutat 1984;6:153-188 (Pubitemid 14118501)
-
(1984)
Environmental Mutagenesis
, vol.6
, Issue.2
, pp. 153-188
-
-
Graf, U.1
Wurgler, F.E.2
Katz, A.J.3
-
22
-
-
0032618378
-
Use of non-mammalian species in bioassays for carcinogenicity
-
Bunton TE. Use of non-mammalian species in bioassays for carcinogenicity. IARC Sci Publ 1999;146:151-184
-
(1999)
IARC Sci Publ
, vol.146
, pp. 151-184
-
-
Bunton, T.E.1
-
23
-
-
0036533795
-
Lessons from animal models of Huntington's disease
-
DOI 10.1016/S0168-9525(01)02625-7, PII S0168952501026257
-
Rubinsztein DC. Lessons from animal models of Huntington's disease. Trends Genet 2002;18:202-209 (Pubitemid 34273741)
-
(2002)
Trends in Genetics
, vol.18
, Issue.4
, pp. 202-209
-
-
Rubinsztein, D.C.1
-
24
-
-
7644239149
-
Drosophila, an emerging model for cardiac disease
-
DOI 10.1016/j.gene.2004.07.018, PII S0378111904004597
-
Bier E, Bodmer R. Drosophila, an emerging model for cardiac disease. Gene 2004;342:1-11 (Pubitemid 39457171)
-
(2004)
Gene
, vol.342
, Issue.1
, pp. 1-11
-
-
Bier, E.1
Bodmer, R.2
-
25
-
-
16644363664
-
Therapeutic targets from a Drosophila model of Alzheimer's disease
-
DOI 10.1016/j.coph.2004.07.001, PII S1471489204001250
-
Crowther DC, Kinghorn KJ, Page R, Lomas DA. Therapeutic targets from a Drosophila model of Alzheimer's disease. Curr Opin Pharmacol 2004;4:513-516 (Pubitemid 40533013)
-
(2004)
Current Opinion in Pharmacology
, vol.4
, Issue.5
, pp. 513-516
-
-
Crowther, D.C.1
Kinghorn, K.J.2
Page, R.3
Lomas, D.A.4
-
26
-
-
33744826241
-
Freshwater microcrustacean Daphnia magna Straus as an early screen model to compare toxicity of acetylcholinesteraseinhibitors
-
Vesela S, Ondruska V, Kuca K, Patocka J. Freshwater microcrustacean Daphnia magna Straus as an early screen model to compare toxicity of acetylcholinesterase inhibitors. J Appl Biomed 2006;4:105-110 (Pubitemid 43834182)
-
(2006)
Journal of Applied Biomedicine
, vol.4
, Issue.2
, pp. 105-110
-
-
Vesela, S.1
Ondruska, V.2
Kuca, K.3
Patocka, J.4
-
27
-
-
27144540463
-
Are innate immune signaling pathways in plants and animals conserved?
-
Ausubel FM. Are innate immune signaling pathways in plants and animals conserved? Nat Immunol 2005;6:973-979
-
(2005)
Nat Immunol
, vol.6
, pp. 973-979
-
-
Ausubel, F.M.1
-
30
-
-
0029848674
-
Haematology and clinical chemistry in rats: Comparison of different blood collection sites
-
Bernardi C, Moneta D, Brughera M, et al. Haematology and clinical chemistry in rats: comparison of different blood collection sites. Comp Haematol Int 1996;6:160-166 (Pubitemid 26390710)
-
(1996)
Comparative Haematology International
, vol.6
, Issue.3
, pp. 160-166
-
-
Bernardi, C.1
Moneta, D.2
Brughera, M.3
Di Salvo, M.4
Lamparelli, D.5
Mazue, G.6
Iatropoulos, M.J.7
-
31
-
-
70349325985
-
New federal-legislation can be effective in fighting terrorism of animal rights extremists
-
Rich B. New federal-legislation can be effective in fighting terrorism of animal rights extremists. Scientist 1993;7:12
-
(1993)
Scientist
, vol.7
, pp. 12
-
-
Rich, B.1
-
34
-
-
0021828124
-
Cytopathological and numerical changes in hemocytes of Periplaneta americana after treatment with malathion
-
Saxena SC, Saxena PN. Cytopathological and numerical changes in hemocytes of Periplaneta americana after treatment with malathion. Bull Environ Contam Toxicol 1985;34:842-849
-
(1985)
Bull Environ Contam Toxicol
, vol.34
, pp. 842-849
-
-
Saxena, S.C.1
Saxena, P.N.2
-
35
-
-
0026551620
-
Induction of micronuclei in hemocytes of Mytilus edulis and statistical analysis
-
Wrisberg MN, Bilbo CM, Spliid H. Induction of micronuclei in hemocytes of Mytilus edulis and statistical analysis. Ecotoxicol Environ Saf 1992;23:191-205
-
(1992)
Ecotoxicol Environ Saf
, vol.23
, pp. 191-205
-
-
Wrisberg, M.N.1
Bilbo, C.M.2
Spliid, H.3
-
36
-
-
0029143512
-
Genotoxicity testing - Current practices and strategies used by the pharmaceutical industry
-
Purves D, Harvey C, Tweats D, Lumley CE. Genotoxicity testing - current practices and strategies used by the pharmaceutical industry. Mutagenesis 1995;10:297-305
-
(1995)
Mutagenesis
, vol.10
, pp. 297-305
-
-
Purves, D.1
Harvey, C.2
Tweats, D.3
Lumley, C.E.4
-
37
-
-
0036167107
-
Drosophila innate immunity: An evolutionary perspective
-
DOI 10.1038/ni0202-121
-
Hoffmann JA, Reichhart JM. Drosophila innate immunity: an evolutionary perspective. Nat Immunol 2002;3:121-126 (Pubitemid 34141441)
-
(2002)
Nature Immunology
, vol.3
, Issue.2
, pp. 121-126
-
-
Hoffmann, J.A.1
Reichhart, J.-M.2
-
38
-
-
0001105986
-
An ultrastructural study of the haemopoietic organs of the silkworm, Bombyx mori
-
Akai H, Sato S. An ultrastructural study of the haemopoietic organs of the silkworm, Bombyx mori. J Insect Physiol 1971;17:1665-1676
-
(1971)
J Insect Physiol
, vol.17
, pp. 1665-1676
-
-
Akai, H.1
Sato, S.2
-
39
-
-
0000128754
-
Haemopoiesis in Lepidoptera. I. The multiplication of circulating haemocytes
-
Arnold JW, Hinks CF. Haemopoiesis in Lepidoptera. I. The multiplication of circulating haemocytes. Can J Zool 1976;54:1003-1012
-
(1976)
Can J Zool
, vol.54
, pp. 1003-1012
-
-
Arnold, J.W.1
Hinks, C.F.2
-
40
-
-
4644293902
-
PVF2, a PDGF/VEGF-like growth factor, induces hemocyte proliferation in Drosophila larvae
-
DOI 10.1093/embo-reports/kvf242
-
Munier A-I, Doucet D, Perrodou E, et al. PVF2, a PDGF/VEGF-like growth factor, induces hemocyte proliferation in Drosophila larvae. EMBO Rep 2002;3:1195-1200 (Pubitemid 36105010)
-
(2002)
EMBO Reports
, vol.3
, Issue.12
, pp. 1195-1200
-
-
Munier, A.-I.1
Doucet, D.2
Perrodou, E.3
Zachary, D.4
Meister, M.5
Hoffmann, J.A.6
Janeway Jr., C.A.7
Lagueux, M.8
-
41
-
-
70349476757
-
Does preclinical testing on insects help to predict human myelotoxic potentials?
-
Berger J. Does preclinical testing on insects help to predict human myelotoxic potentials? Altern Anim Test Exp 2008;14:539-541
-
(2008)
Altern Anim Test Exp
, vol.14
, pp. 539-541
-
-
Berger, J.1
-
42
-
-
0001812738
-
Hemocyte types: Their structures, synonymies, interrelationships, and taxonomic significance
-
Gupta AP, ed. New York: Cambridge University Press
-
Gupta AP. Hemocyte types: their structures, synonymies, interrelationships, and taxonomic significance. In: Gupta AP, ed. Insect Hemocytes. New York: Cambridge University Press, 1979:85-127
-
(1979)
Insect Hemocytes
, pp. 85-127
-
-
Gupta, A.P.1
-
43
-
-
33749660946
-
Influence of metyrapone on the morphology of hemocytes of the Egyptian cotton leafworm Spodoptera littoralis (Boisd.)
-
Gelbic I, Strbackova J, Berger J. Influence of metyrapone on the morphology of hemocytes of the Egyptian cotton leafworm Spodoptera littoralis (Boisd). Zool Stud 2006;45:371-377 (Pubitemid 44554058)
-
(2006)
Zoological Studies
, vol.45
, Issue.3
, pp. 371-377
-
-
Gelbic, I.1
Strbackova, J.2
Berger, J.3
-
44
-
-
33646365052
-
Insect haemocytes: What type of cell is that?
-
Ribeiro C, Brehélin N. Insect haemocytes: what type of cell is that? J Insect Physiol 2006;52:417-429
-
(2006)
J Insect Physiol
, vol.52
, pp. 417-429
-
-
Ribeiro, C.1
Brehélin, N.2
-
45
-
-
70349474288
-
Morphological characterisation of the haemocytes in the adult linden bug, Pyrrhocoris apterus (L.) (Heteroptera)
-
Berger J, Slavickova K. Morphological characterisation of the haemocytes in the adult linden bug, Pyrrhocoris apterus (L.) (Heteroptera). Zool Stud 2008;47:466-472
-
(2008)
Zool Stud
, vol.47
, pp. 466-472
-
-
Berger, J.1
Slavickova, K.2
-
46
-
-
0036784566
-
Insect hemocytes and their role in immunity
-
Lavine MD, Strand MR. Insect hemocytes and their role in immunity. Insect Biochem Mol Biol 2002;32:1295-1309
-
(2002)
Insect Biochem Mol Biol
, vol.32
, pp. 1295-1309
-
-
Lavine, M.D.1
Strand, M.R.2
-
47
-
-
34047268684
-
The host defense of Drosophila melanogaster
-
Lemaitre B, Hoffmann J. The host defense of Drosophila melanogaster. Annu Rev Immunol 2007;25:697-743
-
(2007)
Annu Rev Immunol
, vol.25
, pp. 697-743
-
-
Lemaitre, B.1
Hoffmann, J.2
-
48
-
-
0034616310
-
Specification of Drosophila hematopoietic lineage by conserved transcription factors
-
DOI 10.1126/science.288.5463.146
-
Lebestky T, Chang T, Hartenstein V, Banerjee U. Specification of Drosophila hematopoietic lineage by conserved transcription factors. Science 2000;288:146-149 (Pubitemid 30203049)
-
(2000)
Science
, vol.288
, Issue.5463
, pp. 146-149
-
-
Lebestky, T.1
Chang, T.2
Hartenstein, V.3
Banerjee, U.4
-
49
-
-
34247103287
-
Drosophila hemopoiesis and cellular imunity
-
Williams MJ. Drosophila hemopoiesis and cellular imunity. J Immunol 2007;178:4711-4716
-
(2007)
J Immunol
, vol.178
, pp. 4711-4716
-
-
Williams, M.J.1
-
51
-
-
34249341697
-
Distinct signalling pathways promote phagocytosis of bacteria, latex beads and lipopolysaccharide in medfly haemocytes
-
DOI 10.1111/j.1365-2567.2007.02576.x
-
Lamprou I, Mamali I, Dallas K, Fertakis V, Lampropoulou M, Marmaras VJ. Distinct signalling pathways promote phagocytosis of bacteria, latex beads and lipopolysaccharide in medfly haemocytes. Immunology 2007;121:314-327 (Pubitemid 46817353)
-
(2007)
Immunology
, vol.121
, Issue.3
, pp. 314-327
-
-
Lamprou, I.1
Mamali, I.2
Dallas, K.3
Fertakis, V.4
Lampropoulou, M.5
Marmaras, V.J.6
-
52
-
-
70349476346
-
Phagocytosis of Pyrrhocorris apterus haemocytes
-
Berger J, ed. Ceske Budejovice: Kopp Publishing
-
Burešová V, Berger J. Phagocytosis of Pyrrhocorris apterus haemocytes. In: Berger J, ed. Cells III. Ceske Budejovice: Kopp Publishing, 2002:178
-
(2002)
Cells III
, pp. 178
-
-
Burešová, V.1
Berger, J.2
-
53
-
-
33845575834
-
phox to the cell membrane in activated hemocytes of Galleria mellonella
-
DOI 10.1016/j.dci.2006.06.007, PII S0145305X06001194
-
Renwick J, Reeves EP, Wientjes FB, Kavanagh K. Translocation of proteins homologous to human neutrophil p47(phox) and p67(phox) to the cell membrane in activated hemocytes of Galleria mellonella. Dev Comp Immunol 2007;31:347-359 (Pubitemid 44937765)
-
(2007)
Developmental and Comparative Immunology
, vol.31
, Issue.4
, pp. 347-359
-
-
Renwick, J.1
Reeves, E.P.2
Wientjes, F.B.3
Kavanagh, K.4
|