Ex vivo characterization of early secretory antigenic target 6-specific T cells at sites of active disease in pleural tuberculosis

Clinical Infectious Diseases

Volumn 40, Issue 1, 2005, Pages 184-187

  Wilkinson, Katalin A ^a,b   Wilkinson, Hubert J ^b,c   Pathan, Ansar ^a   Ewer, Katie ^a   Prakash, Manyu ^a   Klenerman, Paul ^a   Maskell, Nick ^a   Davies, Robert ^a   Pasvol, Geoffrey ^b,c   Lalvani, Ajit ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^c NORTHWICK PARK HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; EARLY SECRETORY ANTIGENIC TARGET 6; GAMMA INTERFERON; LYMPHOCYTE ANTIGEN; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CLINICAL ARTICLE; HUMAN; HUMAN CELL; IMMUNOREACTIVITY; INTERFERON PRODUCTION; LYMPHOCYTE COUNT; PLEURA EFFUSION; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION; TUBERCULOUS PLEURISY;

ADULT; ANTIGENS, BACTERIAL; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; BACTERIAL PROTEINS; FEMALE; HUMANS; INTERFERON TYPE II; LYMPHOCYTE ACTIVATION; MALE; PLEURAL EFFUSION; T-LYMPHOCYTE SUBSETS; TUBERCULOSIS, PLEURAL;

EID: 19944429607     PISSN: 10584838     EISSN: None     Source Type: Journal    
DOI: 10.1086/426139     Document Type: Article

References (14)

1. Murray CJ, Lopez AD. Mortality by cause for eight regions of the world: Global Burden of Disease Study. Lancet 1997; 349:1269-76.
2. North RJ, Jung YJ. Immunity to tuberculosis. Annu Rev Immunol 2004; 22:599-623.
3. Condos R, Rom WN, Liu YM, Schluger NW. Local immune responses correlate with presentation and outcome in tuberculosis. Am J Respir Crit Care Med 1998; 157:729-35.
4. Lalvani A, Pathan AA, Durkan H, et al. Enhanced contact tracing and spatial tracking of Mycobacterium tuberculosis infection by enumeration of antigen-specific T cells. Lancet 2001; 357:2017-21.
5. Lalvani A, Pathan AA, McShane H, et al. Rapid detection of Mycobacterium tuberculosis infection by enumeration of antigen-specific T cells. Am J Respir Crit Care Med 2001; 163:824-8.
6. Andersen P, Andersen AB, Sorensen AL, Nagai S. Recall of long-lived immunity to Mycobacterium tuberculosis infection in mice. J Immunol 1995; 154:3359-72.
7. Pathan AA, Wilkinson KA, Klenerman P, et al. Direct ex vivo analysis of antigen-specific IFN-gamma-secreting CD4 T cells in Mycobacterium tuberculosis-infected individuals: associations with clinical disease state and effect of treatment. J Immunol 2001; 167:5217-25.
8. Valdes L, Alvarez D, San Jose E, et al. Tuberculous pleurisy: a study of 254 patients. Arch Intern Med 1998; 158:2017-21.
9. Lalvani A, Nagvenkar P, Udwadia Z, et al. Enumeration of T cells specific for RD1-encoded antigens suggests a high prevalence of latent Mycobacterium tuberculosis infection in healthy urban Indians. J Infect Dis 2001; 183:469-77.
10. Pathan AA, Wilkinson KA, Wilkinson RJ, et al. High frequencies of circulating IFN-gamma-secreting CD8 cytotoxic T cells specific for a novel MHC class I-restricted Mycobacterium tuberculosis epitope in M. tuberculosis- infected subjects without disease. Eur J Immunol 2000; 30:2713-21.
11. + T lymphocyte subpopulation in tuberculous pleuritis. J Immunol 1989; 142:1114-9.
12. Wilkinson RJ, Vordermeier HM, Wilkinson KA, et al. Peptide-specific T cell response to Mycobacterium tuberculosis: clinical spectrum, compartmentalization, and effect of chemotherapy. J Infect Dis 1998; 178:760-8.
13. Aoe K, Hiraki A, Murakami T, et al. Diagnostic significance of interferon-gamma in tuberculous pleural effusions. Chest 2003; 123:740-41.
14. Wongtim S, Silachamroon U, Ruxrungtham K, et al. Interferon gamma for diagnosing tuberculous pleural effusions. Thorax 1999; 54:921-4.