Cellular senescence of human mammary epithelial cells (HMEC) is associated with an altered MMP-7/HB-EGF signaling and increased formation of elastin-like structures

Mechanisms of Ageing and Development

Volumn 130, Issue 10, 2009, Pages 657-669

  Bertram, Catharina ^a   Hass, Ralf ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Aging; Breast cancer; Cellular senescence; Extracellular matrix; Matrix metalloproteinases

Indexed keywords

ELASTIN; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; MATRILYSIN; PROTEIN LYSINE 6 OXIDASE; TRANSCRIPTION FACTOR FRA 1; TROPOELASTIN;

ARTICLE; BREAST EPITHELIUM; CELL AGING; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; RNA INTERFERENCE; SIGNAL TRANSDUCTION;

CELL AGING; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P16; ELASTIN; EPITHELIAL CELLS; FEMALE; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MAMMARY GLANDS, HUMAN; MATRIX METALLOPROTEINASE 7; MIDDLE AGED; PROTEIN-LYSINE 6-OXIDASE; PROTO-ONCOGENE PROTEINS C-FOS; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TIME FACTORS; TROPOELASTIN;

EID: 70349434680     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mad.2009.08.001     Document Type: Article

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