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Volumn 117, Issue 8, 2009, Pages 281-291

Exercise and muscle dysfunction in COPD: Implications for pulmonary rehabilitation

Author keywords

Exercise; Muscle dysfunction; Obstructive pulmonary disease; Pulmonary rehabilitation; Quadriceps; Skeletal muscle

Indexed keywords

5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; ACETYLCYSTEINE; ANABOLIC AGENT; ANTIOXIDANT; BRONCHODILATING AGENT; CARBOCISTEINE; CORTICOSTEROID; CYCLOSPORIN; HELIOX; LIGASE INHIBITOR; NANDROLONE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA AGONIST; PLACEBO; PROTEIN SYNTHESIS INHIBITOR; RECOMBINANT GROWTH HORMONE; TESTOSTERONE; TIOTROPIUM BROMIDE; TUMOR NECROSIS FACTOR ALPHA ANTIBODY;

EID: 70349382690     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/CS20080660     Document Type: Review
Times cited : (42)

References (121)
  • 1
    • 70249103858 scopus 로고    scopus 로고
    • Skeletal muscle dysfunction in COPD: Clinical and laboratory observations
    • Man, W. D.-C., Kemp, P., Moxham, J. and Polkey, M. I. (2009) Skeletal muscle dysfunction in COPD: clinical and laboratory observations. Clin. Sci. 117, 251-264
    • (2009) Clin. Sci , vol.117 , pp. 251-264
    • Man, W.D.-C.1    Kemp, P.2    Moxham, J.3    Polkey, M.I.4
  • 2
    • 0019461587 scopus 로고
    • Exercise training fails to increase skeletal muscle enzymes in patients with chronic obstructive pulmonary disease
    • Belman, M. J. and Kendregan, B. A. (1981) Exercise training fails to increase skeletal muscle enzymes in patients with chronic obstructive pulmonary disease. Am. Rev. Respir. Dis. 123, 256-261
    • (1981) Am. Rev. Respir. Dis , vol.123 , pp. 256-261
    • Belman, M.J.1    Kendregan, B.A.2
  • 6
    • 0031685110 scopus 로고    scopus 로고
    • Histochemical and morphological characteristics of the vastus lateralis muscle in patients with chronic obstructive pulmonary disease
    • Whittom, F., Jobin, J., Simard, P. M., Leblanc, P., Simard, C., Bernard, S., Belleau, R. and Maltais, F. (1998) Histochemical and morphological characteristics of the vastus lateralis muscle in patients with chronic obstructive pulmonary disease. Med. Sci. Sports Exercise 30, 1467-1474
    • (1998) Med. Sci. Sports Exercise , vol.30 , pp. 1467-1474
    • Whittom, F.1    Jobin, J.2    Simard, P.M.3    Leblanc, P.4    Simard, C.5    Bernard, S.6    Belleau, R.7    Maltais, F.8
  • 8
    • 0034663447 scopus 로고    scopus 로고
    • Short- and long-term effects of outpatient rehabilitation in patients with chronic obstructive pulmonary disease: A randomized trial
    • Troosters, T., Gosselink, R. and Decramer, M. (2000) Short- and long-term effects of outpatient rehabilitation in patients with chronic obstructive pulmonary disease: a randomized trial. Am. J. Med. 109, 207-212
    • (2000) Am. J. Med , vol.109 , pp. 207-212
    • Troosters, T.1    Gosselink, R.2    Decramer, M.3
  • 9
    • 70349472651 scopus 로고    scopus 로고
    • Pulmonary Rehabilitation Survey , British Lung Foundation, London
    • Pulmonary Rehabilitation Survey (2003) British Thoracic Society, British Lung Foundation, London
    • (2003) British Thoracic Society
  • 10
    • 33748480212 scopus 로고    scopus 로고
    • Regular physical activity reduces hospital admission and mortality in chronic obstructive pulmonary disease: A population based cohort study
    • Garcia-Aymerich, J., Lange, P., Benet, M., Schnohr, P. and Anto, J. M. (2006) Regular physical activity reduces hospital admission and mortality in chronic obstructive pulmonary disease: a population based cohort study. Thorax 61, 772-778
    • (2006) Thorax , vol.61 , pp. 772-778
    • Garcia-Aymerich, J.1    Lange, P.2    Benet, M.3    Schnohr, P.4    Anto, J.M.5
  • 12
    • 0035991317 scopus 로고    scopus 로고
    • Resistance versus endurance training in patients with COPD and peripheral muscle weakness
    • Spruit, M. A., Gosselin, R., Troosters, T., De Paepe, K. and Decramer, M. (2002) Resistance versus endurance training in patients with COPD and peripheral muscle weakness. Eur. Respir. J. 19, 1072-1078
    • (2002) Eur. Respir. J , vol.19 , pp. 1072-1078
    • Spruit, M.A.1    Gosselin, R.2    Troosters, T.3    De Paepe, K.4    Decramer, M.5
  • 13
    • 0035006873 scopus 로고    scopus 로고
    • Transitions of muscle fiber phenotypic profiles
    • Pette, D. and Staron, R. S. (2001) Transitions of muscle fiber phenotypic profiles. Histochem. Cell Biol. 115, 359-372
    • (2001) Histochem. Cell Biol , vol.115 , pp. 359-372
    • Pette, D.1    Staron, R.S.2
  • 14
    • 34447628323 scopus 로고    scopus 로고
    • Loss of skeletal muscle mass in aging: Examining the relationship of starvation, sarcopenia and cachexia
    • Thomas, D. R. (2007) Loss of skeletal muscle mass in aging: examining the relationship of starvation, sarcopenia and cachexia. Clin. Nutr. 26, 389-399
    • (2007) Clin. Nutr , vol.26 , pp. 389-399
    • Thomas, D.R.1
  • 15
    • 23944456384 scopus 로고    scopus 로고
    • Skeletal muscle hypertrophy and atrophy signaling pathways
    • Glass, D. J. (2005) Skeletal muscle hypertrophy and atrophy signaling pathways. Int. J. Biochem. Cell Biol. 37, 1974-1984
    • (2005) Int. J. Biochem. Cell Biol , vol.37 , pp. 1974-1984
    • Glass, D.J.1
  • 17
  • 18
    • 4544355935 scopus 로고    scopus 로고
    • Calcineurin and calcium/ calmodulin-dependent protein kinase activate distinct metabolic gene regulatory programs in cardiac muscle
    • Schaeffer, P. J., Wende, A. R., Magee, C. J., Neilson, J. R., Leone, T. C., Chen, F. and Kelly, D. P. (2004) Calcineurin and calcium/ calmodulin-dependent protein kinase activate distinct metabolic gene regulatory programs in cardiac muscle. J. Biol. Chem. 279, 39593-39603
    • (2004) J. Biol. Chem , vol.279 , pp. 39593-39603
    • Schaeffer, P.J.1    Wende, A.R.2    Magee, C.J.3    Neilson, J.R.4    Leone, T.C.5    Chen, F.6    Kelly, D.P.7
  • 19
    • 0242467675 scopus 로고    scopus 로고
    • Calcineurin is not involved in some mitochondrial enzyme adaptations to endurance exercise training in rat skeletal muscle
    • Terada, S., Nakagawa, H., Nakamura, Y. and Muraoka, I. (2003) Calcineurin is not involved in some mitochondrial enzyme adaptations to endurance exercise training in rat skeletal muscle. Eur. J. Appl. Physiol. 90, 210-217
    • (2003) Eur. J. Appl. Physiol , vol.90 , pp. 210-217
    • Terada, S.1    Nakagawa, H.2    Nakamura, Y.3    Muraoka, I.4
  • 21
    • 0242582447 scopus 로고    scopus 로고
    • Skeletal muscle reprogramming by activation of calcineurin improves insulin action on metabolic pathways
    • Ryder, J. W., Bassel-Duby, R., Olson, E. N. and Zierath, J. R. (2003) Skeletal muscle reprogramming by activation of calcineurin improves insulin action on metabolic pathways. J. Biol. Chem. 278, 44298-44304
    • (2003) J. Biol. Chem , vol.278 , pp. 44298-44304
    • Ryder, J.W.1    Bassel-Duby, R.2    Olson, E.N.3    Zierath, J.R.4
  • 22
    • 14644411018 scopus 로고    scopus 로고
    • Calcineurin does not mediate exercise-induced increase in muscle GLUT4
    • Garcia-Roves, P. M., Jones, T. E., Otani, K., Han, D. H. and Holloszy, J. O. (2005) Calcineurin does not mediate exercise-induced increase in muscle GLUT4. Diabetes 54, 624-628
    • (2005) Diabetes , vol.54 , pp. 624-628
    • Garcia-Roves, P.M.1    Jones, T.E.2    Otani, K.3    Han, D.H.4    Holloszy, J.O.5
  • 28
    • 0033977890 scopus 로고    scopus 로고
    • The coactivator PGC-1 cooperates with peroxisome proliferator-activated receptor α in transcriptional control of nuclear genes encoding mitochondrial fatty acid oxidation enzymes
    • Vega, R. B., Huss, J. M. and Kelly, D. P. (2000) The coactivator PGC-1 cooperates with peroxisome proliferator-activated receptor α in transcriptional control of nuclear genes encoding mitochondrial fatty acid oxidation enzymes. Mol. Cell. Biol. 20, 1868-1876
    • (2000) Mol. Cell. Biol , vol.20 , pp. 1868-1876
    • Vega, R.B.1    Huss, J.M.2    Kelly, D.P.3
  • 29
    • 0036903174 scopus 로고    scopus 로고
    • Adaptations of skeletal muscle to exercise: Rapid increase in the transcriptional coactivator PGC-1
    • Baar, K., Wende, A. R., Jones, T. E., Marison, M., Nolte, L. A., Chen, M., Kelly, D. P. and Holloszy, J. O. (2002) Adaptations of skeletal muscle to exercise: rapid increase in the transcriptional coactivator PGC-1. FASEB J. 16, 1879-1886
    • (2002) FASEB J , vol.16 , pp. 1879-1886
    • Baar, K.1    Wende, A.R.2    Jones, T.E.3    Marison, M.4    Nolte, L.A.5    Chen, M.6    Kelly, D.P.7    Holloszy, J.O.8
  • 30
    • 45149108625 scopus 로고    scopus 로고
    • Muscle-specific expression of PPAR? coactivator-1α improves exercise performance and increases peak oxygen uptake
    • Calvo, J. A., Daniels, T. G., Wang, X., Paul, A., Lin, J., Spiegelman, B. M., Stevenson, S. C. and Rangwala, S. M. (2008) Muscle-specific expression of PPAR? coactivator-1α improves exercise performance and increases peak oxygen uptake. J. Appl. Physiol. 104, 1304-1312
    • (2008) J. Appl. Physiol , vol.104 , pp. 1304-1312
    • Calvo, J.A.1    Daniels, T.G.2    Wang, X.3    Paul, A.4    Lin, J.5    Spiegelman, B.M.6    Stevenson, S.C.7    Rangwala, S.M.8
  • 31
    • 35648937073 scopus 로고    scopus 로고
    • Skeletal muscle fiber-type switching, exercise intolerance, and myopathy in PGC-1α muscle-specific knock-out animals
    • Handschin, C., Chin, S., Li, P., Liu, F., Maratos-Flier, E., Lebrasseur, N. K., Yan, Z. and Spiegelman, B. M. (2007) Skeletal muscle fiber-type switching, exercise intolerance, and myopathy in PGC-1α muscle-specific knock-out animals. J. Biol. Chem. 282, 30014-30021
    • (2007) J. Biol. Chem , vol.282 , pp. 30014-30021
    • Handschin, C.1    Chin, S.2    Li, P.3    Liu, F.4    Maratos-Flier, E.5    Lebrasseur, N.K.6    Yan, Z.7    Spiegelman, B.M.8
  • 32
    • 10744228606 scopus 로고    scopus 로고
    • Endurance training in humans leads to fiber type-specific increases in levels of peroxisome proliferator-activated receptor-γ coactivator-1 and peroxisome proliferator-activated receptor-α in skeletal muscle
    • Russell, A. P., Feilchenfeldt, J., Schreiber, S., Praz, M., Crettenand, A., Gobelet, C., Meier, C. A., Bell, D. R., Kralli, A., Giacobino, J. P. and Deriaz, O. (2003) Endurance training in humans leads to fiber type-specific increases in levels of peroxisome proliferator-activated receptor-γ coactivator-1 and peroxisome proliferator-activated receptor-α in skeletal muscle. Diabetes 52, 2874-2881
    • (2003) Diabetes , vol.52 , pp. 2874-2881
    • Russell, A.P.1    Feilchenfeldt, J.2    Schreiber, S.3    Praz, M.4    Crettenand, A.5    Gobelet, C.6    Meier, C.A.7    Bell, D.R.8    Kralli, A.9    Giacobino, J.P.10    Deriaz, O.11
  • 34
    • 0042423598 scopus 로고    scopus 로고
    • Effects of chronic AICAR treatment on fiber composition, enzyme activity, UCP3, and PGC-1 in rat muscles
    • Suwa, M., Nakano, H. and Kumagai, S. (2003) Effects of chronic AICAR treatment on fiber composition, enzyme activity, UCP3, and PGC-1 in rat muscles. J. Appl. Physiol. 95, 960-968
    • (2003) J. Appl. Physiol , vol.95 , pp. 960-968
    • Suwa, M.1    Nakano, H.2    Kumagai, S.3
  • 35
    • 0033949848 scopus 로고    scopus 로고
    • Activation of AMP-activated protein kinase increases mitochondrial enzymes in skeletal muscle
    • Winder,W.W., Holmes, B. F., Rubink, D. S., Jensen, E. B., Chen, M. and Holloszy, J. O. (2000) Activation of AMP-activated protein kinase increases mitochondrial enzymes in skeletal muscle. J. Appl. Physiol. 88, 2219-2226
    • (2000) J. Appl. Physiol , vol.88 , pp. 2219-2226
    • Winder, W.W.1    Holmes, B.F.2    Rubink, D.S.3    Jensen, E.B.4    Chen, M.5    Holloszy, J.O.6
  • 36
    • 34547610976 scopus 로고    scopus 로고
    • Skeletal muscle adaptation to exercise training: AMP-activated protein kinase mediates muscle fiber type shift
    • Rockl, K. S., Hirshman, M. F., Brandauer, J., Fujii, N., Witters, L. A. and Goodyear, L. J. (2007) Skeletal muscle adaptation to exercise training: AMP-activated protein kinase mediates muscle fiber type shift. Diabetes 56, 2062-2069
    • (2007) Diabetes , vol.56 , pp. 2062-2069
    • Rockl, K.S.1    Hirshman, M.F.2    Brandauer, J.3    Fujii, N.4    Witters, L.A.5    Goodyear, L.J.6
  • 39
    • 34547545892 scopus 로고    scopus 로고
    • AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1α
    • Jager, S., Handschin, C., St-Pierre, J. and Spiegelman, B. M. (2007) AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1α. Proc. Natl. Acad. Sci. U.S.A. 104, 12017-12022
    • (2007) Proc. Natl. Acad. Sci. U.S.A , vol.104 , pp. 12017-12022
    • Jager, S.1    Handschin, C.2    St-Pierre, J.3    Spiegelman, B.M.4
  • 40
    • 33750718800 scopus 로고    scopus 로고
    • Interaction between the AMP-activated protein kinase and mTOR signaling pathways
    • Kimball, S. R. (2006) Interaction between the AMP-activated protein kinase and mTOR signaling pathways. Med. Sci. Sports Exercise 38, 1958-1964
    • (2006) Med. Sci. Sports Exercise , vol.38 , pp. 1958-1964
    • Kimball, S.R.1
  • 41
    • 34249703500 scopus 로고    scopus 로고
    • AMP-activated protein kinase agonists increase mRNA content of the muscle-specific ubiquitin ligases MAFbx and MuRF1 in C2C12 cells
    • Krawiec, B. J.,Nystrom, G. J., Frost, R. A., Jefferson, L. S. and Lang, C. H. (2007) AMP-activated protein kinase agonists increase mRNA content of the muscle-specific ubiquitin ligases MAFbx and MuRF1 in C2C12 cells. Am. J. Physiol. Endocrinol. Metab. 292, E1555-E1567
    • (2007) Am. J. Physiol. Endocrinol. Metab , vol.292
    • Krawiec, B.J.1    Nystrom, G.J.2    Frost, R.A.3    Jefferson, L.S.4    Lang, C.H.5
  • 42
    • 0029008035 scopus 로고
    • Effects of pulmonary rehabilitation on physiologic and psychosocial outcomes in patients with chronic obstructive pulmonary disease
    • Ries, A. L., Kaplan, R. M., Limberg, T. M. and Prewitt, L. M. (1995) Effects of pulmonary rehabilitation on physiologic and psychosocial outcomes in patients with chronic obstructive pulmonary disease. Ann. Intern. Med. 122, 823-832
    • (1995) Ann. Intern. Med , vol.122 , pp. 823-832
    • Ries, A.L.1    Kaplan, R.M.2    Limberg, T.M.3    Prewitt, L.M.4
  • 44
    • 0031747543 scopus 로고    scopus 로고
    • General exercise training improves ventilatory and peripheral muscle strength and endurance in chronic airflow limitation
    • O'Donnell, D. E., McGuire, M., Samis, L. and Webb, K. A. (1998) General exercise training improves ventilatory and peripheral muscle strength and endurance in chronic airflow limitation. Am. J. Respir. Crit. Care Med. 157, 1489-1497
    • (1998) Am. J. Respir. Crit. Care Med , vol.157 , pp. 1489-1497
    • O'Donnell, D.E.1    McGuire, M.2    Samis, L.3    Webb, K.A.4
  • 48
    • 0242721245 scopus 로고    scopus 로고
    • A role for anabolic steroids in the rehabilitation of patients with COPD? A double-blind, placebo-controlled, randomized trial
    • Creutzberg, E. C., Wouters, E. F., Mostert, R., Pluymers, R. J. and Schols, A. M. (2003) A role for anabolic steroids in the rehabilitation of patients with COPD? A double-blind, placebo-controlled, randomized trial. Chest 124, 1733-1742
    • (2003) Chest , vol.124 , pp. 1733-1742
    • Creutzberg, E.C.1    Wouters, E.F.2    Mostert, R.3    Pluymers, R.J.4    Schols, A.M.5
  • 50
    • 0025964922 scopus 로고
    • Reductions in exercise lactic acidosis and ventilation as a result of exercise training in patients with obstructive lung disease
    • Casaburi, R., Patessio, A., Ioli, F., Zanaboni, S., Donner, C. F. and Wasserman, K. (1991) Reductions in exercise lactic acidosis and ventilation as a result of exercise training in patients with obstructive lung disease. Am. Rev. Respir. Dis. 143, 9-18
    • (1991) Am. Rev. Respir. Dis , vol.143 , pp. 9-18
    • Casaburi, R.1    Patessio, A.2    Ioli, F.3    Zanaboni, S.4    Donner, C.F.5    Wasserman, K.6
  • 52
    • 26844457553 scopus 로고    scopus 로고
    • From muscle disuse to myopathy in COPD: Potential contribution of oxidative stress
    • Couillard, A. and Prefaut, C. (2005) From muscle disuse to myopathy in COPD: potential contribution of oxidative stress. Eur. Respir. J. 26, 703-719
    • (2005) Eur. Respir. J , vol.26 , pp. 703-719
    • Couillard, A.1    Prefaut, C.2
  • 53
    • 33750081753 scopus 로고    scopus 로고
    • Skeletal muscles in chronic obstructive pulmonary disease: Deconditioning, or myopathy?
    • Wagner, P. D. (2006) Skeletal muscles in chronic obstructive pulmonary disease: deconditioning, or myopathy? Respirology 11, 681-686
    • (2006) Respirology , vol.11 , pp. 681-686
    • Wagner, P.D.1
  • 55
    • 0034007932 scopus 로고    scopus 로고
    • Long-term effects of outpatient rehabilitation of COPD: A randomized trial
    • Guell, R., Casan, P., Belda, J., Sangenis, M., Morante, F., Guyatt, G. H. and Sanchis, J. (2000) Long-term effects of outpatient rehabilitation of COPD: a randomized trial. Chest 117, 976-983
    • (2000) Chest , vol.117 , pp. 976-983
    • Guell, R.1    Casan, P.2    Belda, J.3    Sangenis, M.4    Morante, F.5    Guyatt, G.H.6    Sanchis, J.7
  • 56
    • 33748529930 scopus 로고    scopus 로고
    • How long should outpatient pulmonary rehabilitation be? A randomised controlled trial of 4 weeks versus 7 weeks
    • Sewell, L., Singh, S. J., Williams, J. E., Collier, R. and Morgan, M. D. (2006) How long should outpatient pulmonary rehabilitation be? A randomised controlled trial of 4 weeks versus 7 weeks. Thorax 61, 767-771
    • (2006) Thorax , vol.61 , pp. 767-771
    • Sewell, L.1    Singh, S.J.2    Williams, J.E.3    Collier, R.4    Morgan, M.D.5
  • 58
    • 0030012048 scopus 로고    scopus 로고
    • Inhaled bronchodilators reduce dynamic hyperinflation during exercise in patients with chronic obstructive pulmonary disease
    • Belman, M. J., Botnick, W. C. and Shin, J. W. (1996) Inhaled bronchodilators reduce dynamic hyperinflation during exercise in patients with chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 153, 967-975
    • (1996) Am. J. Respir. Crit. Care Med , vol.153 , pp. 967-975
    • Belman, M.J.1    Botnick, W.C.2    Shin, J.W.3
  • 59
    • 0031760347 scopus 로고    scopus 로고
    • Measurement of symptoms, lung hyperinflation, and endurance during exercise in chronic obstructive pulmonary disease
    • O'Donnell, D. E., Lam, M. and Webb, K. A. (1998) Measurement of symptoms, lung hyperinflation, and endurance during exercise in chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 158, 1557-1565
    • (1998) Am. J. Respir. Crit. Care Med , vol.158 , pp. 1557-1565
    • O'Donnell, D.E.1    Lam, M.2    Webb, K.A.3
  • 61
    • 0035446990 scopus 로고    scopus 로고
    • Dynamic hyperinflation and exercise intolerance in chronic obstructive pulmonary disease
    • O'Donnell, D. E., Revill, S. M. and Webb, K. A. (2001) Dynamic hyperinflation and exercise intolerance in chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 164, 770-777
    • (2001) Am. J. Respir. Crit. Care Med , vol.164 , pp. 770-777
    • O'Donnell, D.E.1    Revill, S.M.2    Webb, K.A.3
  • 62
    • 15844429415 scopus 로고    scopus 로고
    • Improvement in exercise tolerance with the combination of tiotropium and pulmonary rehabilitation in patients with COPD
    • Casaburi, R., Kukafka, D., Cooper, C. B., Witek, Jr, T. J. and Kesten, S. (2005) Improvement in exercise tolerance with the combination of tiotropium and pulmonary rehabilitation in patients with COPD. Chest 127, 809-817
    • (2005) Chest , vol.127 , pp. 809-817
    • Casaburi, R.1    Kukafka, D.2    Cooper, C.B.3    Witek Jr, T.J.4    Kesten, S.5
  • 63
    • 0041827190 scopus 로고    scopus 로고
    • Contractile leg fatigue after cycle exercise: A factor limiting exercise in patients with chronic obstructive pulmonary disease
    • Saey, D., Debigare, R., LeBlanc, P., Mador, M. J., Cote, C. H., Jobin, J. and Maltais, F. (2003) Contractile leg fatigue after cycle exercise: a factor limiting exercise in patients with chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 168, 425-430
    • (2003) Am. J. Respir. Crit. Care Med , vol.168 , pp. 425-430
    • Saey, D.1    Debigare, R.2    LeBlanc, P.3    Mador, M.J.4    Cote, C.H.5    Jobin, J.6    Maltais, F.7
  • 64
    • 0034899623 scopus 로고    scopus 로고
    • Dose-response effect of oxygen on hyperinflation and exercise endurance in nonhypoxaemic COPD patients
    • Somfay, A., Porszasz, J., Lee, S. M. and Casaburi, R. (2001) Dose-response effect of oxygen on hyperinflation and exercise endurance in nonhypoxaemic COPD patients. Eur. Respir. J. 18, 77-84
    • (2001) Eur. Respir. J , vol.18 , pp. 77-84
    • Somfay, A.1    Porszasz, J.2    Lee, S.M.3    Casaburi, R.4
  • 65
    • 0035064316 scopus 로고    scopus 로고
    • Effects of hyperoxia on ventilatory limitation during exercise in advanced chronic obstructive pulmonary disease
    • O'Donnell, D. E., D'Arsigny, C. and Webb, K. A. (2001) Effects of hyperoxia on ventilatory limitation during exercise in advanced chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 163, 892-898
    • (2001) Am. J. Respir. Crit. Care Med , vol.163 , pp. 892-898
    • O'Donnell, D.E.1    D'Arsigny, C.2    Webb, K.A.3
  • 66
    • 0031058778 scopus 로고    scopus 로고
    • Factors contributing to relief of exertional breathlessness during hyperoxia in chronic airflow limitation
    • O'Donnell, D. E., Bain, D. J. and Webb, K. A. (1997) Factors contributing to relief of exertional breathlessness during hyperoxia in chronic airflow limitation. Am. J. Respir. Crit. Care Med. 155, 530-535
    • (1997) Am. J. Respir. Crit. Care Med , vol.155 , pp. 530-535
    • O'Donnell, D.E.1    Bain, D.J.2    Webb, K.A.3
  • 67
    • 0020041806 scopus 로고
    • Mechanisms of oxygen effects on exercise in patients with chronic obstructive pulmonary disease
    • Stein, D. A., Bradley, B. L. and Miller, W. C. (1982) Mechanisms of oxygen effects on exercise in patients with chronic obstructive pulmonary disease. Chest 81, 6-10
    • (1982) Chest , vol.81 , pp. 6-10
    • Stein, D.A.1    Bradley, B.L.2    Miller, W.C.3
  • 69
    • 0034124456 scopus 로고    scopus 로고
    • Supplemental oxygen during pulmonary rehabilitation in patients with COPD with exercise hypoxaemia
    • Garrod, R., Paul, E. A. and Wedzicha, J. A. (2000) Supplemental oxygen during pulmonary rehabilitation in patients with COPD with exercise hypoxaemia. Thorax 55, 539-543
    • (2000) Thorax , vol.55 , pp. 539-543
    • Garrod, R.1    Paul, E.A.2    Wedzicha, J.A.3
  • 70
    • 0034857229 scopus 로고    scopus 로고
    • Physical training with and without oxygen in patients with chronic obstructive pulmonary disease and exercise-induced hypoxaemia
    • Wadell, K., Henriksson-Larsen, K. and Lundgren, R. (2001) Physical training with and without oxygen in patients with chronic obstructive pulmonary disease and exercise-induced hypoxaemia. J. Rehabil. Med. 33, 200-205
    • (2001) J. Rehabil. Med , vol.33 , pp. 200-205
    • Wadell, K.1    Henriksson-Larsen, K.2    Lundgren, R.3
  • 71
  • 73
    • 0036036474 scopus 로고    scopus 로고
    • Effects of training with heliox and noninvasive positive pressure ventilation on exercise ability in patients with severe COPD
    • Johnson, J. E., Gavin, D. J. and Adams-Dramiga, S. (2002) Effects of training with heliox and noninvasive positive pressure ventilation on exercise ability in patients with severe COPD. Chest 122, 464-472
    • (2002) Chest , vol.122 , pp. 464-472
    • Johnson, J.E.1    Gavin, D.J.2    Adams-Dramiga, S.3
  • 74
    • 0037464756 scopus 로고    scopus 로고
    • Non-invasive positive pressure ventilation to treat respiratory failure resulting from exacerbations of chronic obstructive pulmonary disease: Cochrane systematic review and meta-analysis
    • Lightowler, J. V., Wedzicha, J. A., Elliott, M. W. and Ram, F. S. (2003) Non-invasive positive pressure ventilation to treat respiratory failure resulting from exacerbations of chronic obstructive pulmonary disease: Cochrane systematic review and meta-analysis. Br. Med. J. 326, 185
    • (2003) Br. Med. J , vol.326 , pp. 185
    • Lightowler, J.V.1    Wedzicha, J.A.2    Elliott, M.W.3    Ram, F.S.4
  • 75
    • 0028296316 scopus 로고
    • Physiologic effects of positive end-expiratory pressure and mask pressure support during exacerbations of chronic obstructive pulmonary disease
    • Appendini, L., Patessio, A., Zanaboni, S., Carone, M., Gukov, B., Donner, C. F. and Rossi, A. (1994) Physiologic effects of positive end-expiratory pressure and mask pressure support during exacerbations of chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 149, 1069-1076
    • (1994) Am. J. Respir. Crit. Care Med , vol.149 , pp. 1069-1076
    • Appendini, L.1    Patessio, A.2    Zanaboni, S.3    Carone, M.4    Gukov, B.5    Donner, C.F.6    Rossi, A.7
  • 76
    • 0028090399 scopus 로고
    • Effect of inspiratory pressure support on exercise tolerance and breathlessness in patients with severe stable chronic obstructive pulmonary disease
    • Keilty, S. E., Ponte, J., Fleming, T. A. and Moxham, J. (1994) Effect of inspiratory pressure support on exercise tolerance and breathlessness in patients with severe stable chronic obstructive pulmonary disease. Thorax 49, 990-994
    • (1994) Thorax , vol.49 , pp. 990-994
    • Keilty, S.E.1    Ponte, J.2    Fleming, T.A.3    Moxham, J.4
  • 77
    • 0028916049 scopus 로고
    • Pressure support reduces inspiratory effort and dyspnea during exercise in chronic airflow obstruction
    • Maltais, F., Reissmann, H. and Gottfried, S. B. (1995) Pressure support reduces inspiratory effort and dyspnea during exercise in chronic airflow obstruction. Am. J. Respir. Crit. Care Med. 151, 1027-1033
    • (1995) Am. J. Respir. Crit. Care Med , vol.151 , pp. 1027-1033
    • Maltais, F.1    Reissmann, H.2    Gottfried, S.B.3
  • 78
    • 0036793695 scopus 로고    scopus 로고
    • Proportional assist ventilation as an aid to exercise training in severe chronic obstructive pulmonary disease
    • Hawkins, P., Johnson, L. C., Nikoletou, D., Hamnegard, C. H., Sherwood, R., Polkey, M. I. and Moxham, J. (2002) Proportional assist ventilation as an aid to exercise training in severe chronic obstructive pulmonary disease. Thorax 57, 853-859
    • (2002) Thorax , vol.57 , pp. 853-859
    • Hawkins, P.1    Johnson, L.C.2    Nikoletou, D.3    Hamnegard, C.H.4    Sherwood, R.5    Polkey, M.I.6    Moxham, J.7
  • 79
    • 0041632422 scopus 로고    scopus 로고
    • Noninvasive ventilation during exercise training improves exercise tolerance in patients with chronic obstructive pulmonary disease
    • Costes, F., Agresti, A., Court-Fortune, I., Roche, F., Vergnon, J. M. and Barthelemy, J. C. (2003) Noninvasive ventilation during exercise training improves exercise tolerance in patients with chronic obstructive pulmonary disease. J. Cardiopulm. Rehabil. 23, 307-313
    • (2003) J. Cardiopulm. Rehabil , vol.23 , pp. 307-313
    • Costes, F.1    Agresti, A.2    Court-Fortune, I.3    Roche, F.4    Vergnon, J.M.5    Barthelemy, J.C.6
  • 80
    • 0036587058 scopus 로고    scopus 로고
    • Lack of additional effect of adjunct of assisted ventilation to pulmonary rehabilitation in mild COPD patients
    • Bianchi, L., Foglio, K., Porta, R., Baiardi, R., Vitacca, M. and Ambrosino, N. (2002) Lack of additional effect of adjunct of assisted ventilation to pulmonary rehabilitation in mild COPD patients. Respir. Med. 96, 359-367
    • (2002) Respir. Med , vol.96 , pp. 359-367
    • Bianchi, L.1    Foglio, K.2    Porta, R.3    Baiardi, R.4    Vitacca, M.5    Ambrosino, N.6
  • 81
    • 0033863192 scopus 로고    scopus 로고
    • Randomized controlled trial of ambulatory oxygen and an ambulatory ventilator on endurance exercise in COPD
    • Revill, S. M., Singh, S. J. and Morgan, M. D. (2000) Randomized controlled trial of ambulatory oxygen and an ambulatory ventilator on endurance exercise in COPD. Respir. Med. 94, 778-783
    • (2000) Respir. Med , vol.94 , pp. 778-783
    • Revill, S.M.1    Singh, S.J.2    Morgan, M.D.3
  • 82
    • 9244255243 scopus 로고    scopus 로고
    • Community pulmonary rehabilitation after hospitalisation for acute exacerbations of chronic obstructive pulmonary disease: Randomised controlled study
    • Man, W. D., Polkey, M. I., Donaldson, N., Gray, B. J. and Moxham, J. (2004) Community pulmonary rehabilitation after hospitalisation for acute exacerbations of chronic obstructive pulmonary disease: randomised controlled study. Br. Med. J. 329, 1209
    • (2004) Br. Med. J , vol.329 , pp. 1209
    • Man, W.D.1    Polkey, M.I.2    Donaldson, N.3    Gray, B.J.4    Moxham, J.5
  • 83
    • 0034518695 scopus 로고    scopus 로고
    • Home-based exercise is capable of preserving hospital-based improvements in severe chronic obstructive pulmonary disease
    • Behnke, M., Taube, C., Kirsten, D., Lehnigk, B., Jorres, R. A. and Magnussen, H. (2000) Home-based exercise is capable of preserving hospital-based improvements in severe chronic obstructive pulmonary disease. Respir. Med. 94, 1184-1191
    • (2000) Respir. Med , vol.94 , pp. 1184-1191
    • Behnke, M.1    Taube, C.2    Kirsten, D.3    Lehnigk, B.4    Jorres, R.A.5    Magnussen, H.6
  • 84
    • 0033773925 scopus 로고    scopus 로고
    • Randomized controlled trial of domiciliary noninvasive positive pressure ventilation and physical training in severe chronic obstructive pulmonary disease
    • Garrod, R., Mikelsons, C., Paul, E. A. and Wedzicha, J. A. (2000) Randomized controlled trial of domiciliary noninvasive positive pressure ventilation and physical training in severe chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 162, 1335-1341
    • (2000) Am. J. Respir. Crit. Care Med , vol.162 , pp. 1335-1341
    • Garrod, R.1    Mikelsons, C.2    Paul, E.A.3    Wedzicha, J.A.4
  • 85
    • 0014360476 scopus 로고
    • Maximal respiratory pressures in chronic obstructive lung disease
    • Byrd, R. B. and Hyatt, R. E. (1968) Maximal respiratory pressures in chronic obstructive lung disease. Am. Rev. Respir. Dis. 98, 848-856
    • (1968) Am. Rev. Respir. Dis , vol.98 , pp. 848-856
    • Byrd, R.B.1    Hyatt, R.E.2
  • 86
    • 0042031410 scopus 로고    scopus 로고
    • Non-volitional assessment of skeletal muscle strength in patients with chronic obstructive pulmonary disease
    • Man, W. D., Soliman, M. G., Nikoletou, D., Harris, M. L., Rafferty, G. F., Mustfa, N., Polkey, M. I. and Moxham, J. (2003) Non-volitional assessment of skeletal muscle strength in patients with chronic obstructive pulmonary disease. Thorax 58, 665-669
    • (2003) Thorax , vol.58 , pp. 665-669
    • Man, W.D.1    Soliman, M.G.2    Nikoletou, D.3    Harris, M.L.4    Rafferty, G.F.5    Mustfa, N.6    Polkey, M.I.7    Moxham, J.8
  • 87
    • 0026008893 scopus 로고
    • Contractile properties of the human diaphragm during chronic hyperinflation
    • Similowski, T., Yan, S., Gauthier, A. P., Macklem, P. T. and Bellemare, F. (1991) Contractile properties of the human diaphragm during chronic hyperinflation. N. Engl. J. Med. 325, 917-923
    • (1991) N. Engl. J. Med , vol.325 , pp. 917-923
    • Similowski, T.1    Yan, S.2    Gauthier, A.P.3    Macklem, P.T.4    Bellemare, F.5
  • 88
    • 0031467474 scopus 로고    scopus 로고
    • Cellular adaptations in the diaphragm in chronic obstructive pulmonary disease
    • Levine, S., Kaiser, L., Leferovich, J. and Tikunov, B. (1997) Cellular adaptations in the diaphragm in chronic obstructive pulmonary disease. N. Engl. J. Med. 337, 1799-1806
    • (1997) N. Engl. J. Med , vol.337 , pp. 1799-1806
    • Levine, S.1    Kaiser, L.2    Leferovich, J.3    Tikunov, B.4
  • 91
    • 0036738093 scopus 로고    scopus 로고
    • Effects of controlled inspiratory muscle training in patients with COPD: A meta-analysis
    • Lotters, F., van Tol, B., Kwakkel, G. and Gosselink, R. (2002) Effects of controlled inspiratory muscle training in patients with COPD: a meta-analysis. Eur. Respir. J. 20, 570-576
    • (2002) Eur. Respir. J , vol.20 , pp. 570-576
    • Lotters, F.1    van Tol, B.2    Kwakkel, G.3    Gosselink, R.4
  • 93
    • 0036221213 scopus 로고    scopus 로고
    • Home based neuromuscular electrical stimulation as a new rehabilitative strategy for severely disabled patients with chronic obstructive pulmonary disease (COPD)
    • Neder, J. A., Sword, D., Ward, S. A., Mackay, E., Cochrane, L. M. and Clark, C. J. (2002) Home based neuromuscular electrical stimulation as a new rehabilitative strategy for severely disabled patients with chronic obstructive pulmonary disease (COPD). Thorax 57, 333-337
    • (2002) Thorax , vol.57 , pp. 333-337
    • Neder, J.A.1    Sword, D.2    Ward, S.A.3    Mackay, E.4    Cochrane, L.M.5    Clark, C.J.6
  • 94
    • 0036897846 scopus 로고    scopus 로고
    • Randomised controlled trial of transcutaneous electrical muscle stimulation of the lower extremities in patients with chronic obstructive pulmonary disease
    • Bourjeily-Habr, G., Rochester, C. L., Palermo, F., Snyder, P. and Mohsenin, V. (2002) Randomised controlled trial of transcutaneous electrical muscle stimulation of the lower extremities in patients with chronic obstructive pulmonary disease. Thorax 57, 1045-1049
    • (2002) Thorax , vol.57 , pp. 1045-1049
    • Bourjeily-Habr, G.1    Rochester, C.L.2    Palermo, F.3    Snyder, P.4    Mohsenin, V.5
  • 95
    • 0038498288 scopus 로고    scopus 로고
    • Peripheral muscle strength training in bed-bound patients with COPD receiving mechanical ventilation: Effect of electrical stimulation
    • Zanotti, E., Felicetti, G., Maini, M. and Fracchia, C. (2003) Peripheral muscle strength training in bed-bound patients with COPD receiving mechanical ventilation: effect of electrical stimulation. Chest 124, 292-296
    • (2003) Chest , vol.124 , pp. 292-296
    • Zanotti, E.1    Felicetti, G.2    Maini, M.3    Fracchia, C.4
  • 96
    • 0027287584 scopus 로고
    • Prevalence and characteristics of nutritional depletion in patients with stable COPD eligible for pulmonary rehabilitation
    • Schols, A. M., Soeters, P. B., Dingemans, A. M., Mostert, R., Frantzen, P. J. and Wouters, E. F. (1993) Prevalence and characteristics of nutritional depletion in patients with stable COPD eligible for pulmonary rehabilitation. Am. Rev. Respir. Dis. 147, 1151-1156
    • (1993) Am. Rev. Respir. Dis , vol.147 , pp. 1151-1156
    • Schols, A.M.1    Soeters, P.B.2    Dingemans, A.M.3    Mostert, R.4    Frantzen, P.J.5    Wouters, E.F.6
  • 97
    • 30344482545 scopus 로고    scopus 로고
    • Body mass, fat-free body mass, and prognosis in patients with chronic obstructive pulmonary disease from a random population sample: Findings from the Copenhagen City Heart Study
    • Vestbo, J., Prescott, E., Almdal, T., Dahl, M., Nordestgaard, B. G., Andersen, T., Sorensen, T. I. and Lange, P. (2006) Body mass, fat-free body mass, and prognosis in patients with chronic obstructive pulmonary disease from a random population sample: findings from the Copenhagen City Heart Study. Am. J. Respir. Crit. Care Med. 173, 79-83
    • (2006) Am. J. Respir. Crit. Care Med , vol.173 , pp. 79-83
    • Vestbo, J.1    Prescott, E.2    Almdal, T.3    Dahl, M.4    Nordestgaard, B.G.5    Andersen, T.6    Sorensen, T.I.7    Lange, P.8
  • 98
    • 0042027383 scopus 로고    scopus 로고
    • Nutritional enhancement of exercise performance in chronic obstructive pulmonary disease: A randomised controlled trial
    • Steiner, M. C., Barton, R. L., Singh, S. J. and Morgan, M. D. (2003) Nutritional enhancement of exercise performance in chronic obstructive pulmonary disease: a randomised controlled trial. Thorax 58, 745-751
    • (2003) Thorax , vol.58 , pp. 745-751
    • Steiner, M.C.1    Barton, R.L.2    Singh, S.J.3    Morgan, M.D.4
  • 99
    • 0025347641 scopus 로고
    • The effects of refeeding on peripheral and respiratory muscle function in malnourished chronic obstructive pulmonary disease patients
    • Whittaker, J. S., Ryan, C. F., Buckley, P. A. and Road, J. D. (1990) The effects of refeeding on peripheral and respiratory muscle function in malnourished chronic obstructive pulmonary disease patients. Am. Rev. Respir. Dis. 142, 283-288
    • (1990) Am. Rev. Respir. Dis , vol.142 , pp. 283-288
    • Whittaker, J.S.1    Ryan, C.F.2    Buckley, P.A.3    Road, J.D.4
  • 100
    • 0034565341 scopus 로고    scopus 로고
    • Nutritional supplementation in stable chronic obstructive pulmonary disease
    • Rev, CD000998, doi:10.1002/ 14651858.CD000998.pub2
    • Ferreira, I. M., Brooks, D., Lacasse, Y. and Goldstein, R. S. (2000) Nutritional supplementation in stable chronic obstructive pulmonary disease. Cochrane Database Syst. Rev., CD000998, doi:10.1002/ 14651858.CD000998.pub2
    • (2000) Cochrane Database Syst
    • Ferreira, I.M.1    Brooks, D.2    Lacasse, Y.3    Goldstein, R.S.4
  • 101
    • 0037317984 scopus 로고    scopus 로고
    • Efficacy of nutritional supplementation therapy in depleted patients with chronic obstructive pulmonary disease
    • Creutzberg, E. C., Wouters, E. F., Mostert, R., Weling-Scheepers, C. A. and Schols, A. M. (2003) Efficacy of nutritional supplementation therapy in depleted patients with chronic obstructive pulmonary disease. Nutrition 19, 120-127
    • (2003) Nutrition , vol.19 , pp. 120-127
    • Creutzberg, E.C.1    Wouters, E.F.2    Mostert, R.3    Weling-Scheepers, C.A.4    Schols, A.M.5
  • 102
    • 0036036456 scopus 로고    scopus 로고
    • Reversal of COPD-associated weight loss using the anabolic agent oxandrolone
    • Yeh, S. S., DeGuzman, B. and Kramer, T. (2002) Reversal of COPD-associated weight loss using the anabolic agent oxandrolone. Chest 122, 421-428
    • (2002) Chest , vol.122 , pp. 421-428
    • Yeh, S.S.1    DeGuzman, B.2    Kramer, T.3
  • 103
    • 0029118877 scopus 로고
    • Physiologic effects of nutritional support and anabolic steroids in patients with chronic obstructive pulmonary disease. A placebo-controlled randomized trial
    • Schols, A. M., Soeters, P. B., Mostert, R., Pluymers, R. J. and Wouters, E. F. (1995) Physiologic effects of nutritional support and anabolic steroids in patients with chronic obstructive pulmonary disease. A placebo-controlled randomized trial. Am. J. Respir. Crit. Care Med. 152, 1268-1274
    • (1995) Am. J. Respir. Crit. Care Med , vol.152 , pp. 1268-1274
    • Schols, A.M.1    Soeters, P.B.2    Mostert, R.3    Pluymers, R.J.4    Wouters, E.F.5
  • 104
    • 0031817306 scopus 로고    scopus 로고
    • The influence of 6 months of oral anabolic steroids on body mass and respiratory muscles in undernourished COPD patients
    • Ferreira, I. M., Verreschi, I. T., Nery, L. E., Goldstein, R. S., Zamel, N., Brooks, D. and Jardim, J. R. (1998) The influence of 6 months of oral anabolic steroids on body mass and respiratory muscles in undernourished COPD patients. Chest 114, 19-28
    • (1998) Chest , vol.114 , pp. 19-28
    • Ferreira, I.M.1    Verreschi, I.T.2    Nery, L.E.3    Goldstein, R.S.4    Zamel, N.5    Brooks, D.6    Jardim, J.R.7
  • 108
    • 0031436628 scopus 로고    scopus 로고
    • Administration of growth hormone to underweight patients with chronic obstructive pulmonary disease. A prospective, randomized, controlled study
    • Burdet, L., de Muralt, B., Schutz, Y., Pichard, C. and Fitting, J.W. (1997) Administration of growth hormone to underweight patients with chronic obstructive pulmonary disease. A prospective, randomized, controlled study. Am. J. Respir. Crit. Care Med. 156, 1800-1806
    • (1997) Am. J. Respir. Crit. Care Med , vol.156 , pp. 1800-1806
    • Burdet, L.1    de Muralt, B.2    Schutz, Y.3    Pichard, C.4    Fitting, J.W.5
  • 109
    • 0031965872 scopus 로고    scopus 로고
    • Localized infusion of IGF-I results in skeletal muscle hypertrophy in rats
    • Adams, G. R. and McCue, S. A. (1998) Localized infusion of IGF-I results in skeletal muscle hypertrophy in rats. J. Appl. Physiol. 84, 1716-1722
    • (1998) J. Appl. Physiol , vol.84 , pp. 1716-1722
    • Adams, G.R.1    McCue, S.A.2
  • 110
    • 18444393384 scopus 로고    scopus 로고
    • Musculoskeletal effects of the recombinant human IGF-I/IGF binding protein-3 complex in osteoporotic patients with proximal femoral fracture: A double-blind, placebo-controlled pilot study
    • Boonen, S., Rosen, C., Bouillon, R., Sommer, A., McKay, M., Rosen, D., Adams, S., Broos, P., Lenaerts, J., Raus, J. et al. (2002) Musculoskeletal effects of the recombinant human IGF-I/IGF binding protein-3 complex in osteoporotic patients with proximal femoral fracture: a double-blind, placebo-controlled pilot study. J. Clin. Endocrinol. Metab. 87, 1593-1599
    • (2002) J. Clin. Endocrinol. Metab , vol.87 , pp. 1593-1599
    • Boonen, S.1    Rosen, C.2    Bouillon, R.3    Sommer, A.4    McKay, M.5    Rosen, D.6    Adams, S.7    Broos, P.8    Lenaerts, J.9    Raus, J.10
  • 112
    • 44849100529 scopus 로고    scopus 로고
    • Effect of carbocisteine on acute exacerbation of chronic obstructive pulmonary disease (PEACE Study): A randomised placebo-controlled study
    • Zheng, J. P., Kang, J., Huang, S. G., Chen, P., Yao, W. Z., Yang, L., Bai, C. X., Wang, C. Z., Wang, C., Chen, B. Y. et al. (2008) Effect of carbocisteine on acute exacerbation of chronic obstructive pulmonary disease (PEACE Study): a randomised placebo-controlled study. Lancet 371, 2013-2018
    • (2008) Lancet , vol.371 , pp. 2013-2018
    • Zheng, J.P.1    Kang, J.2    Huang, S.G.3    Chen, P.4    Yao, W.Z.5    Yang, L.6    Bai, C.X.7    Wang, C.Z.8    Wang, C.9    Chen, B.Y.10
  • 113
    • 0027499233 scopus 로고
    • Effects of an antioxidant vitamin mixture on lipid peroxidation at rest and postexercise
    • Kanter, M. M., Nolte, L. A. and Holloszy, J. O. (1993) Effects of an antioxidant vitamin mixture on lipid peroxidation at rest and postexercise. J. Appl. Physiol. 74, 965-969
    • (1993) J. Appl. Physiol , vol.74 , pp. 965-969
    • Kanter, M.M.1    Nolte, L.A.2    Holloszy, J.O.3
  • 115
    • 28444474549 scopus 로고    scopus 로고
    • Therapeutic prospects to treat skeletal muscle wasting in COPD (chronic obstructive lung disease)
    • Hansen, M. J., Gualano, R. C., Bozinovski, S., Vlahos, R. and Anderson, G. P. (2006) Therapeutic prospects to treat skeletal muscle wasting in COPD (chronic obstructive lung disease). Pharmacol. Ther. 109, 162-172
    • (2006) Pharmacol. Ther , vol.109 , pp. 162-172
    • Hansen, M.J.1    Gualano, R.C.2    Bozinovski, S.3    Vlahos, R.4    Anderson, G.P.5
  • 120
    • 47949104798 scopus 로고    scopus 로고
    • The role of exercise and PGC1α in inflammation and chronic disease
    • Handschin, C. and Spiegelman, B. M. (2008) The role of exercise and PGC1α in inflammation and chronic disease. Nature 454, 463-469
    • (2008) Nature , vol.454 , pp. 463-469
    • Handschin, C.1    Spiegelman, B.M.2
  • 121
    • 42449092519 scopus 로고    scopus 로고
    • Gene expression-based screening identifies microtubule inhibitors as inducers of PGC-1α and oxidative phosphorylation
    • Arany, Z., Wagner, B. K., Ma, Y., Chinsomboon, J., Laznik, D. and Spiegelman, B. M. (2008) Gene expression-based screening identifies microtubule inhibitors as inducers of PGC-1α and oxidative phosphorylation. Proc. Natl. Acad. Sci. U.S.A. 105, 4721-4726
    • (2008) Proc. Natl. Acad. Sci. U.S.A , vol.105 , pp. 4721-4726
    • Arany, Z.1    Wagner, B.K.2    Ma, Y.3    Chinsomboon, J.4    Laznik, D.5    Spiegelman, B.M.6


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