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Volumn 124, Issue 5, 2003, Pages 1733-1742

A Role for Anabolic Steroids in the Rehabilitation of Patients with COPD? A Double-Blind, Placebo-Controlled, Randomized Trial

Author keywords

Anabolic steroids; Body composition; COPD; Erythropoietin; Exercise capacity; Health status; Muscle function; Nandrolone decanoate; Oral glucocorticosteroids; Testosterone

Indexed keywords

ANABOLIC AGENT; ARACHIS OIL; BROMIDE; DEUTERIUM; ERYTHROPOIETIN; GLUCOCORTICOID; HEMOGLOBIN; NANDROLONE DECANOATE;

EID: 0242721245     PISSN: 00123692     EISSN: None     Source Type: Journal    
DOI: 10.1378/chest.124.5.1733     Document Type: Article
Times cited : (164)

References (45)
  • 1
    • 0032943991 scopus 로고    scopus 로고
    • Dyspnea: Mechanisms, assessment, and management; a consensus statement
    • Meek PM, Schwartzstein RM, Adams L, et al. Dyspnea: mechanisms, assessment, and management; a consensus statement. Am J Respir Crit Care Med 1999; 159:321-340
    • (1999) Am J Respir Crit Care Med , vol.159 , pp. 321-340
    • Meek, P.M.1    Schwartzstein, R.M.2    Adams, L.3
  • 2
    • 0028892391 scopus 로고
    • Muscle strength, symptom intensity, and exercise capacity in patients with cardiorespiratory disorders
    • Hamilton AL, Killian KJ, Summers E, et al. Muscle strength, symptom intensity, and exercise capacity in patients with cardiorespiratory disorders. Am J Respir Crit Care Med 1995; 152:2021-2031
    • (1995) Am J Respir Crit Care Med , vol.152 , pp. 2021-2031
    • Hamilton, A.L.1    Killian, K.J.2    Summers, E.3
  • 3
    • 0028143215 scopus 로고
    • Nutritional depletion in relation to respiratory and peripheral skeletal muscle function in out-patients with COPD
    • Engelen MPKJ, Schols AMWJ, Baken WC, et al. Nutritional depletion in relation to respiratory and peripheral skeletal muscle function in out-patients with COPD. Eur Respir J 1994; 7:1793-1797
    • (1994) Eur Respir J , vol.7 , pp. 1793-1797
    • Engelen, M.P.K.J.1    Schols, A.M.W.J.2    Baken, W.C.3
  • 4
    • 0027287584 scopus 로고
    • Prevalence and characteristics of nutritional depletion in patients with stable COPD eligible for pulmonary rehabilitation
    • Schols AMWJ, Soeters PB, Dingemans AM, et al. Prevalence and characteristics of nutritional depletion in patients with stable COPD eligible for pulmonary rehabilitation. Am Rev Respir Dis 1993; 147:1151-1156
    • (1993) Am Rev Respir Dis , vol.147 , pp. 1151-1156
    • Schols, A.M.W.J.1    Soeters, P.B.2    Dingemans, A.M.3
  • 5
    • 0031952987 scopus 로고    scopus 로고
    • Testosterone levels in men with chronic obstructive pulmonary disease with or without glucocorticoid therapy
    • Kamischke A, Kemper DE, Castel MA, et al. Testosterone levels in men with chronic obstructive pulmonary disease with or without glucocorticoid therapy. Eur Respir J 1998; 11: 41-45
    • (1998) Eur Respir J , vol.11 , pp. 41-45
    • Kamischke, A.1    Kemper, D.E.2    Castel, M.A.3
  • 6
    • 0028237807 scopus 로고
    • Corticosteroids contribute to muscle weakness in chronic airflow obstruction
    • Decramer M, Lacquet LM, Fagard R, et al. Corticosteroids contribute to muscle weakness in chronic airflow obstruction. Am J Respir Crit Care Med 1994; 150:11-16
    • (1994) Am J Respir Crit Care Med , vol.150 , pp. 11-16
    • Decramer, M.1    Lacquet, L.M.2    Fagard, R.3
  • 7
    • 0031846340 scopus 로고    scopus 로고
    • Peripheral muscle weakness in patients with chronic obstructive pulmonary disease
    • Bernard S, LeBlanc P, Whittom F, et al. Peripheral muscle weakness in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1998; 158:629-634
    • (1998) Am J Respir Crit Care Med , vol.158 , pp. 629-634
    • Bernard, S.1    LeBlanc, P.2    Whittom, F.3
  • 8
    • 0035035768 scopus 로고    scopus 로고
    • Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO global initiative for chronic obstructive lung disease (GOLD) workshop summary
    • Pauwels RA, Buist AS, Calverley PM, et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO global initiative for chronic obstructive lung disease (GOLD) workshop summary Am J Respir Crit Care Med 2001; 163:1256-1276
    • (2001) Am J Respir Crit Care Med , vol.163 , pp. 1256-1276
    • Pauwels, R.A.1    Buist, A.S.2    Calverley, P.M.3
  • 9
    • 0029118877 scopus 로고
    • Physiologic effects of nutritional support and anabolic steroids in patients with chronic obstructive pulmonary disease: A placebo-controlled randomized trial
    • Schols AMWJ, Soeters PB, Mostert R, et al. Physiologic effects of nutritional support and anabolic steroids in patients with chronic obstructive pulmonary disease: a placebo-controlled randomized trial. Am J Respir Crit Care Med 1995; 152:1268-1274
    • (1995) Am J Respir Crit Care Med , vol.152 , pp. 1268-1274
    • Schols, A.M.W.J.1    Soeters, P.B.2    Mostert, R.3
  • 10
    • 0031817306 scopus 로고    scopus 로고
    • The influence of 6 months of oral anabolic steroids on body mass and respiratory muscles in undernourished COPD patients
    • Ferreira IM, Verreschi IT, Nery LE, et al. The influence of 6 months of oral anabolic steroids on body mass and respiratory muscles in undernourished COPD patients. Chest 1998; 114:19-28
    • (1998) Chest , vol.114 , pp. 19-28
    • Ferreira, I.M.1    Verreschi, I.T.2    Nery, L.E.3
  • 11
    • 8944233864 scopus 로고    scopus 로고
    • The effects of supraphysiological doses of testosterone on muscle size and strength in normal men
    • Bhasin S, Storer TW, Berman N, et al. The effects of supraphysiological doses of testosterone on muscle size and strength in normal men. N Engl J Med 1996; 335:1-7
    • (1996) N Engl J Med , vol.335 , pp. 1-7
    • Bhasin, S.1    Storer, T.W.2    Berman, N.3
  • 12
    • 0026522921 scopus 로고
    • A controlled trial of recombinant human erythropoietin and nandrolone decanoate in the treatment of anemia in patients on chronic hemodialysis
    • Berns JS, Rudnick MR, Cohen RM. A controlled trial of recombinant human erythropoietin and nandrolone decanoate in the treatment of anemia in patients on chronic hemodialysis. Clin Nephrol 1992; 37:264-267
    • (1992) Clin Nephrol , vol.37 , pp. 264-267
    • Berns, J.S.1    Rudnick, M.R.2    Cohen, R.M.3
  • 13
    • 0031977299 scopus 로고    scopus 로고
    • Anabolic steroids in part reverse glucocorticoid-induced alterations in rat diaphragm
    • van Balkom RHH, Dekhuijzen PNR, Folgering HTM, et al. Anabolic steroids in part reverse glucocorticoid-induced alterations in rat diaphragm. J Appl Physiol 1998; 84:1492-1499
    • (1998) J Appl Physiol , vol.84 , pp. 1492-1499
    • Van Balkom, R.H.H.1    Dekhuijzen, P.N.R.2    Folgering, H.T.M.3
  • 14
    • 0033067444 scopus 로고    scopus 로고
    • Effects of anabolic steroids on diaphragm impairment induced by methylprednisolone in emphysematous hamsters
    • van Balkom RH, Dekhuijzen PN, van der Heijden HF, et al. Effects of anabolic steroids on diaphragm impairment induced by methylprednisolone in emphysematous hamsters. Eur Respir J 1999; 13:1062-1069
    • (1999) Eur Respir J , vol.13 , pp. 1062-1069
    • Van Balkom, R.H.1    Dekhuijzen, P.N.2    Van Der Heijden, H.F.3
  • 15
    • 0028827084 scopus 로고
    • Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease
    • American Thoracic Society. Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1995; 152:S77-S121
    • (1995) Am J Respir Crit Care Med , vol.152
  • 16
    • 0027567430 scopus 로고
    • Standardized lung function testing: Official statement of the European Respiratory Society
    • Quanjer PH. Standardized lung function testing: official statement of the European Respiratory Society. Eur Respir J 1993; 6(suppl 16):1-100
    • (1993) Eur Respir J , vol.6 , Issue.16 SUPPL. , pp. 1-100
    • Quanjer, P.H.1
  • 17
    • 0029266069 scopus 로고
    • The Maastricht protocol for the measurement of body composition and energy expenditure with labeled water
    • Westerterp KR, Wouters L, van Marken Lichtenbelt WD. The Maastricht protocol for the measurement of body composition and energy expenditure with labeled water. Obes Res 1995; 3(Suppl 1):49-57
    • (1995) Obes Res , vol.3 , Issue.1 SUPPL. , pp. 49-57
    • Westerterp, K.R.1    Wouters, L.2    Van Marken Lichtenbelt, W.D.3
  • 18
    • 0014514097 scopus 로고
    • Maximal respiratory pressures: Normal values and relationship to age and sex
    • Black LF, Hyatt RE. Maximal respiratory pressures: normal values and relationship to age and sex. Am Rev Respir Dis 1969; 99:696-702
    • (1969) Am Rev Respir Dis , vol.99 , pp. 696-702
    • Black, L.F.1    Hyatt, R.E.2
  • 20
    • 0031967167 scopus 로고    scopus 로고
    • Metabolic and hemodynamic responses of lower limb during exercise in patients with COPD
    • Maltais F, Jobin J, Sullivan MJ, et al. Metabolic and hemodynamic responses of lower limb during exercise in patients with COPD. J Appl Physiol 1998; 84:1573-1580
    • (1998) J Appl Physiol , vol.84 , pp. 1573-1580
    • Maltais, F.1    Jobin, J.2    Sullivan, M.J.3
  • 21
    • 0029039548 scopus 로고
    • Issues concerning health-related quality of life in COPD
    • Jones PW. Issues concerning health-related quality of life in COPD. Chest 1995; 107:187S-193S
    • (1995) Chest , vol.107
    • Jones, P.W.1
  • 22
    • 0019996101 scopus 로고
    • Influence of nandrolone decanoate on the pituitary-gonadal axis in males
    • Copenh
    • Bijlsma JW, Duursma SA, Thijssen JH, et al. Influence of nandrolone decanoate on the pituitary-gonadal axis in males. Acta Endocrinol (Copenh) 1982; 101:108-112
    • (1982) Acta Endocrinol , vol.101 , pp. 108-112
    • Bijlsma, J.W.1    Duursma, S.A.2    Thijssen, J.H.3
  • 23
    • 0023216074 scopus 로고
    • A symmetric dialysis method for the determination of free testosterone in human plasma
    • Swinkels LM, Ross HA, Benraad TJ. A symmetric dialysis method for the determination of free testosterone in human plasma. Clin Chim Acta 1987; 165:341-349
    • (1987) Clin Chim Acta , vol.165 , pp. 341-349
    • Swinkels, L.M.1    Ross, H.A.2    Benraad, T.J.3
  • 24
    • 0023767413 scopus 로고
    • Salivary and plasma free testosterone and androstenedione levels in women using oral contraceptives containing desogestrel or levonorgestrel
    • Swinkels LM, Meulenberg PM, Ross HA, et al. Salivary and plasma free testosterone and androstenedione levels in women using oral contraceptives containing desogestrel or levonorgestrel. Ann Clin Biochem 1988; 25:354-359
    • (1988) Ann Clin Biochem , vol.25 , pp. 354-359
    • Swinkels, L.M.1    Meulenberg, P.M.2    Ross, H.A.3
  • 25
    • 0033599746 scopus 로고    scopus 로고
    • More consideration to dietary protein in the nutrition of chronically ill adults with tendency to weight loss
    • Sauerwein HP, Romijn JA. More consideration to dietary protein in the nutrition of chronically ill adults with tendency to weight loss [in Dutch]. Ned Tijdschr Geneeskd 1999; 143:886-889
    • (1999) Ned Tijdschr Geneeskd , vol.143 , pp. 886-889
    • Sauerwein, H.P.1    Romijn, J.A.2
  • 26
    • 0021096818 scopus 로고
    • Statistical guidelines for contributors to medical journals
    • Altman DG, Gore SM, Gardner MJ, et al. Statistical guidelines for contributors to medical journals. BMJ (Clin Res Ed) 1983; 286:1489-1493
    • (1983) BMJ (Clin Res Ed) , vol.286 , pp. 1489-1493
    • Altman, D.G.1    Gore, S.M.2    Gardner, M.J.3
  • 27
    • 0032187221 scopus 로고    scopus 로고
    • Therapeutic perspective: Issues in testosterone replacement in older men
    • Bhasin S, Bagatell CJ, Bremner WJ, et al. Therapeutic perspective: issues in testosterone replacement in older men. J Clin Endocrinol Metab 1998; 83:3435-3448
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 3435-3448
    • Bhasin, S.1    Bagatell, C.J.2    Bremner, W.J.3
  • 28
    • 0029819286 scopus 로고    scopus 로고
    • Effects of testosterone replacement on muscle mass and muscle protein synthesis in hypogonadal men-a clinical research center study
    • Brodsky IG, Balagopal P, Nair KS. Effects of testosterone replacement on muscle mass and muscle protein synthesis in hypogonadal men-a clinical research center study. J Clin Endocrinol Metab 1996; 81:3469-3475
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 3469-3475
    • Brodsky, I.G.1    Balagopal, P.2    Nair, K.S.3
  • 29
    • 0027618933 scopus 로고
    • Muscle ultrastructure after strength training with placebo or anabolic steroid
    • Kuipers H, Peeze Binkhorst FM, Hartgens F, et al. Muscle ultrastructure after strength training with placebo or anabolic steroid. Can J Appl Physiol 1993; 18:189-196
    • (1993) Can J Appl Physiol , vol.18 , pp. 189-196
    • Kuipers, H.1    Peeze Binkhorst, F.M.2    Hartgens, F.3
  • 30
    • 0027442221 scopus 로고
    • Anabolic steroids: Action on cellular level
    • Bartsch W. Anabolic steroids: action on cellular level. Wien Med Wochenschr 1993; 143:363-366
    • (1993) Wien Med Wochenschr , vol.143 , pp. 363-366
    • Bartsch, W.1
  • 31
    • 0031730933 scopus 로고    scopus 로고
    • Testosterone injection stimulates net protein synthesis but not tissue amino acid transport
    • Ferrando AA, Tipton KD, Doyle D, et al. Testosterone injection stimulates net protein synthesis but not tissue amino acid transport. Am J Physiol 1998; 275:E864-E871
    • (1998) Am J Physiol , vol.275
    • Ferrando, A.A.1    Tipton, K.D.2    Doyle, D.3
  • 32
    • 0034091919 scopus 로고    scopus 로고
    • Combined effects of hyperaminoacidemia and oxandrolone on skeletal muscle protein synthesis
    • Sheffield-Moore M, Wolfe RR, Gore DC, et al. Combined effects of hyperaminoacidemia and oxandrolone on skeletal muscle protein synthesis. Am J Physiol Endocrinol Metab 2000; 278:E273-E279
    • (2000) Am J Physiol Endocrinol Metab , vol.278
    • Sheffield-Moore, M.1    Wolfe, R.R.2    Gore, D.C.3
  • 34
    • 9444290721 scopus 로고    scopus 로고
    • Skeletal muscle adaptation to endurance training in patients with chronic obstructive pulmonary disease
    • Maltais F, LeBlanc P, Simard C, et al. Skeletal muscle adaptation to endurance training in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1996; 154:442-447
    • (1996) Am J Respir Crit Care Med , vol.154 , pp. 442-447
    • Maltais, F.1    LeBlanc, P.2    Simard, C.3
  • 35
    • 0031924890 scopus 로고    scopus 로고
    • Effects of theophylline and ipratropium bromide on exercise performance in patients with stable chronic obstructive pulmonary disease
    • Tsukino M, Nishimura K, Ikeda A, et al. Effects of theophylline and ipratropium bromide on exercise performance in patients with stable chronic obstructive pulmonary disease. Thorax 1998; 53:269-273
    • (1998) Thorax , vol.53 , pp. 269-273
    • Tsukino, M.1    Nishimura, K.2    Ikeda, A.3
  • 36
    • 0026101874 scopus 로고
    • Androgens potentiate the effects of erythropoietin in the treatment of anemia of end-stage renal disease
    • Ballal SH, Domoto DT, Polack DC, et al. Androgens potentiate the effects of erythropoietin in the treatment of anemia of end-stage renal disease. Am J Kidney Dis 1991; 17:29-33
    • (1991) Am J Kidney Dis , vol.17 , pp. 29-33
    • Ballal, S.H.1    Domoto, D.T.2    Polack, D.C.3
  • 37
    • 0023112668 scopus 로고
    • Androgen therapy in haemodialysis patients: II. Effects on red cell metabolism
    • Solomon LR, Hendler ED. Androgen therapy in haemodialysis patients: II. Effects on red cell metabolism Br J Haematol 1987; 65:223-230
    • (1987) Br J Haematol , vol.65 , pp. 223-230
    • Solomon, L.R.1    Hendler, E.D.2
  • 38
    • 0018891566 scopus 로고
    • Effect of erythrocytes of androgens on 2, 3-diphosphoglycerate in patients with chronic obstructive pulmonary disease
    • Simelaro JP, Venditto M, Ghen MJ, et al. Effect of erythrocytes of androgens on 2, 3-diphosphoglycerate in patients with chronic obstructive pulmonary disease. J Am Osteopath Assoc 1980; 79:388-390
    • (1980) J Am Osteopath Assoc , vol.79 , pp. 388-390
    • Simelaro, J.P.1    Venditto, M.2    Ghen, M.J.3
  • 39
    • 0032864925 scopus 로고    scopus 로고
    • Exercise rehabilitation and chronic obstructive pulmonary disease stage
    • Berry MJ, Rejeski WJ, Adair NE, et al. Exercise rehabilitation and chronic obstructive pulmonary disease stage. Am J Respir Crit Care Med 1999; 160:1248-1253
    • (1999) Am J Respir Crit Care Med , vol.160 , pp. 1248-1253
    • Berry, M.J.1    Rejeski, W.J.2    Adair, N.E.3
  • 40
    • 0033062424 scopus 로고    scopus 로고
    • Aerobic and strength training in patients with chronic obstructive pulmonary disease
    • Bernard S, Whittom F, LeBlanc P, et al. Aerobic and strength training in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1999; 159:896-901
    • (1999) Am J Respir Crit Care Med , vol.159 , pp. 896-901
    • Bernard, S.1    Whittom, F.2    LeBlanc, P.3
  • 41
    • 0033376974 scopus 로고    scopus 로고
    • A comparison of the level of dyspnea vs disease severity in indicating the health-related quality of life of patients with COPD
    • Hajiro T, Nishimura K, Tsukino M, et al. A comparison of the level of dyspnea vs disease severity in indicating the health-related quality of life of patients with COPD. Chest 1999; 116:1632-1637
    • (1999) Chest , vol.116 , pp. 1632-1637
    • Hajiro, T.1    Nishimura, K.2    Tsukino, M.3
  • 42
    • 0027358977 scopus 로고
    • Exertional breathlessness in patients with chronic airflow limitation: The role of lung hyperinflation
    • O'Donnell D, Webb KA. Exertional breathlessness in patients with chronic airflow limitation: the role of lung hyperinflation. Am Rev Respir Dis 1993; 148:1351-1357
    • (1993) Am Rev Respir Dis , vol.148 , pp. 1351-1357
    • O'Donnell, D.1    Webb, K.A.2
  • 44
    • 0030754858 scopus 로고    scopus 로고
    • Androgen and estrogen-androgen hormone replacement therapy: A review of the safety literature, 1941 to 1996
    • Gelfand MM, Wiita B. Androgen and estrogen-androgen hormone replacement therapy: a review of the safety literature, 1941 to 1996. Clin Ther 1997; 19:383-404
    • (1997) Clin Ther , vol.19 , pp. 383-404
    • Gelfand, M.M.1    Wiita, B.2
  • 45
    • 0029080238 scopus 로고
    • Polycythemia as a complication of testosterone replacement therapy in nursing home men with low testosterone levels
    • Drinka PJ, Jochen AL, Cuisinier M, et al. Polycythemia as a complication of testosterone replacement therapy in nursing home men with low testosterone levels. J Am Geriatr Soc 1995; 43:899-901
    • (1995) J Am Geriatr Soc , vol.43 , pp. 899-901
    • Drinka, P.J.1    Jochen, A.L.2    Cuisinier, M.3


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