A new EPR oximetry protocol to estimate the tissue oxygen consumption in vivo

Radiation Research

Volumn 172, Issue 2, 2009, Pages 220-225

  Diepart, Caroline ^a   Jordan, Béńdicte F ^a   Gallez, Bernard ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOGEN; LEVOTHYROXINE; OXYGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREATHING; CONTROLLED STUDY; ELECTRON SPIN RESONANCE; HYPERTHYROIDISM; IN VIVO STUDY; MOUSE; MUSCLE CELL; NONHUMAN; OXIMETRY; OXYGEN CONSUMPTION; OXYGEN SATURATION; OXYGEN TISSUE LEVEL; PRIORITY JOURNAL; TISSUE OXYGENATION; TISSUE PERFUSION; TUMOR CELL; ALGORITHM; ANIMAL; LIVER TUMOR; METABOLISM; METHODOLOGY; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; TUMOR CELL CULTURE;

MUS;

ALGORITHMS; ANIMALS; ELECTRON SPIN RESONANCE SPECTROSCOPY; LIVER NEOPLASMS; MICE; OXIMETRY; OXYGEN; OXYGEN CONSUMPTION; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TUMOR CELLS, CULTURED;

EID: 70349345805     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.1667/RR1448.1     Document Type: Article

References (23)

1. P. Vaupel and L. Harrison, Tumor hypoxia: causative factors, compensatory mechanisms, and cellular response. Oncologist 9 (Suppl. 5), 4-9 (2004).
2. T. W. Secomb, R. Hsu, E. T. Ong, J. F. Gross and M. W. Dewhirst, Analysis of the effects of oxygen supply and demand on hypoxic fraction in tumors. Acta Oncol. 34, 313-316 (1995).
3. J. E. Biaglow, Y. Manevich, D. Leeper, B. Chance, M. W. Dewhirst, W. T. Jenkins, S. W. Tuttle, K. Wroblewski, J. D. Glickson and S. M. Evans, MIBG inhibits respiration: potential for radio- and hyperthermic sensitization. Int. J. Radiat. Oncol. Biol. Phys. 42, 871-876 (1998).
4. B. F. Jordan, V. Gregoire, R. J. Demeure, P. Sonveaux, O. Feron, J. O'Hara, V. P. Vanhulle, N. Delzenne and B. Gallez, Insulin increases the sensitivity of tumors to irradiation: involvement of an increase in tumor oxygenation mediated by a nitric oxide-dependent decrease of the tumor cells oxygen consumption. Cancer Res. 62, 3555-3561 (2002).
5. N. Crokart, K. Radermacher, B. F. Jordan, C. Baudelet, G. O. Cron, V. Gregoire, N. Beghein, C. Bouzin, O. Feron and B. Gallez, Tumor radiosensitization by antiinflammatory drugs: evidence for a new mechanism involving the oxygen effect. Cancer Res. 65, 7911-7916 (2005).
6. N. Crokart, B. F. Jordan, C. Baudelet, G. O. Cron, J. Hotton, K. Radermacher, V. Gregoire, N. Beghein, P. Martinive and B. Gallez, Glucocorticoids modulate tumor radiation response through a decrease in tumor oxygen consumption. Clin. Cancer Res. 13, 630-635 (2007).
7. R. Ansiaux, C. Baudelet, B. F. Jordan, N. Crokart, P. Martinive, J. Dewever, V. Gregoire, O. Feron and B. Gallez, Mechanism of reoxygenation after antiangiogenic therapy using su5416 and its importance for guiding combined antitumor therapy. Cancer Res. 66, 9698-9704 (2006).
8. B. F. Jordan, N. Christian, V. Gregoire, O. Feron and B. Gallez, Thyroid status is a key modulator of tumor oxygenation: Implication for radiation therapy. Radiat. Res. 168, 428-432 (2007).
9. S. A. Snyder, J. L. Lanzen, R. D. Braun, G. Rosner, T. W. Secomb, J. Biaglow, D. M. Brizel and M. W. Dewhirst, Simultaneous administration of glucose and hyperoxic gas achieves greater improvement in tumor oxygenation than hyperoxic gas alone. Int. J. Radiat. Oncol. Biol. Phys. 51, 494-506 (2001).
10. D. K. Kelleher, C. Nauth, O. Thews, W. Krueger and P. Vaupel, Localized hypothermia: impact on oxygenation, microregional perfusion, metabolic and bioenergetic status of subcutaneous rat tumours. Br. J. Cancer 78, 56-61 (1998).
11. B. Gallez, C. Baudelet and B. F. Jordan, Assessment of tumor oxygenation by electron paramagnetic resonance: principles and applications. NMR Biomed. 17, 240-262 (2004).
12. D. S. Vikram, J. L. Zweier and P. Kuppusamy, Methods for noninvasive imaging of tissue hypoxia. Antioxid. Redox Signal. 9, 1745-1756 (2007).
13. 18F]fluorodeoxyglucose. J. Neurosci. Methods 77, 199-209 (1997).
14. M. W. Dewhirst, T. W. Secomb, E. T. Ong, R. Hsu and J. F. Gross, Determination of local oxygen consumption rates in tumors. Cancer Res. 54, 3333-3336 (1994).
15. H. M. Swartz, Using EPR to measure a critical but often unmeasured component of oxidative damage: oxygen. Antioxid. Redox Signal. 6, 677-686 (2004).
16. R. Gredilla, T. M. Lopez, M. Portero-Otin, R. Pamplona and G. Barja, Influence of hyper- and hypothyroidism on lipid peroxidation, unsaturation of phospholipids, glutathione system and oxidative damage to nuclear and mitochondrial DNA in mice skeletal muscle. Mol. Cell. Biochem. 221, 41-48 (2001).
17. B. Gallez, B. F. Jordan, C. Baudelet and P. D. Misson, Pharmacological modifications of the partial pressure of oxygen in murine tumors: evaluation using in vivo EPR oximetry. Magn. Reson. Med. 42, 627-630 (1999).
18. M. W. Dewhirst, E. T. Ong, G. L. Rosner, S. W. Rehmus, S. Shan, R. D. Braun, D. M. Brizel and T. W. Secomb, Arteriolar oxygenation in tumour and subcutaneous arterioles: effects of inspired air oxygen content. Br. J. Cancer Suppl. 27, S241-S246 (1996).
19. M. E. Powell, S. A. Hill, M. I. Saunders, P. J. Hoskin and D. J. Chaplin, Effect of carbogen breathing on tumour microregional blood flow in humans. Radiother. Oncol. 41, 225-231 (1996).
20. R. Ansiaux, C. Baudelet, B. F. Jordan, N. Beghein, P. Sonveaux, W. J. De, P. Martinive, V. Gregoire, O. Feron and B. Gallez, Thalidomide radiosensitizes tumors through early changes in the tumor microenvironment. Clin. Cancer Res. 11, 743-750 (2005).
21. P. Kuppusamy, H. Li, G. Ilangovan, A. J. Cardounel, J. L. Zweier, K. Yamada, M. C. Krishna and J. B. Mitchell, Noninvasive imaging of tumor redox status and its modification by tissue glutathione levels. Cancer Res. 62, 307-312 (2002).
22. G. Ilangovan, H. Li, J. L. Zweier, M. C. Krishna, J. B. Mitchell and P. Kuppusamy, In vivo measurement of regional oxygenation and imaging of redox status in RIF-1 murine tumor: effect of carbogen-breathing. Magn. Reson. Med. 48, 723-730 (2002).
23. 2 measurements by electron paramagnetic resonance oximetry: current status and future potential for experimental and clinical studies. Antioxid. Redox Signal. 9, 1169-1182 (2007).