Thermodynamics of zinc binding to hepatitis C virus NS3 protease: A folding by binding event

Proteins: Structure, Function and Bioinformatics

Volumn 77, Issue 3, 2009, Pages 624-636

  Abian, Olga ^a,b   Neira, Jose Luis ^a,c   Velazquez Campoy, Adrian ^a,d  

^a UNIVERSITY OF ZARAGOZA   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c MIGUEL HERNÁNDEZ UNIVERSITY   (Spain)

^d FUNDACIÓN ARAID   (Spain)

Author keywords

Conformational change; Hepatitis C virus; Isothermal titration calorimetry; Ligand binding; NS3 protease; Thermodynamics; Zinc

Indexed keywords

EDETIC ACID; HYDROLASE; NONSTRUCTURAL PROTEIN 3; PROTEINASE; ZINC;

ARTICLE; BINDING SITE; CONFORMATIONAL TRANSITION; ENERGY TRANSFER; HEPATITIS C VIRUS; METAL BINDING; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN INTERACTION; PROTEIN STRUCTURE; THERMODYNAMICS;

BINDING SITES; CALORIMETRY; DATABASES, PROTEIN; HYDROLYSIS; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PROTEIN BINDING; PROTEIN FOLDING; SPECTROPHOTOMETRY, ULTRAVIOLET; THERMODYNAMICS; VIRAL NONSTRUCTURAL PROTEINS; ZINC;

HEPATITIS C VIRUS;

EID: 70349330154     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.22475     Document Type: Article

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