Optimized RNA Targets of Two Closely Related Triple KH Domain Proteins, Heterogeneous Nuclear Ribonucleoprotein K and αCP-2KL, Suggest Distinct Modes of RNA Recognition

Journal of Biological Chemistry

Volumn 276, Issue 20, 2001, Pages 17484-17496

  Thisted, Thomas ^a   Lyakhov, Dmitry L ^b   Liebhaber, Stephen A ^c  

^a NOVO NORDISK A S   (Denmark)

^b Gen Probe Incorporated   (United States)

^c Clinical Research Bldg ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CELLS; CHEMICAL BONDS; CONFORMATIONS; MUTAGENESIS; PROTEINS;

BINDING SPECIFICITY;

RNA;

ALPHA GLOBIN; ALPHACP 2KL PROTEIN; ARACHIDONATE 15 LIPOXYGENASE; COMPLEMENTARY DNA; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN K; MESSENGER RNA; RECOMBINANT PROTEIN; RIBONUCLEASE; RNA; RNA BINDING PROTEIN; UNCLASSIFIED DRUG; DNA BINDING PROTEIN; HNRPK PROTEIN, HUMAN; OLIGODEOXYRIBONUCLEOTIDE; POLYCYTIDYLIC ACID; PRIMER DNA; RIBONUCLEOPROTEIN; TRANSCRIPTION FACTOR;

3' UNTRANSLATED REGION; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; ERYTHROLEUKEMIA CELL; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; KH DOMAIN; MAMMAL CELL; MOUSE; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN MOTIF; RNA BINDING; RNA SEQUENCE; ANIMAL; CHEMISTRY; CONFORMATION; CONSENSUS SEQUENCE; ENZYME SPECIFICITY; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; RNA PROCESSING;

ANIMALIA; MAMMALIA;

ANIMALS; BASE SEQUENCE; BINDING SITES; CONSENSUS SEQUENCE; DNA PRIMERS; DNA-BINDING PROTEINS; HETEROGENEOUS-NUCLEAR RIBONUCLEOPROTEIN K; HETEROGENEOUS-NUCLEAR RIBONUCLEOPROTEINS; HUMANS; MICE; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; OLIGODEOXYRIBONUCLEOTIDES; POLY C; POLYMERASE CHAIN REACTION; RECOMBINANT PROTEINS; RIBONUCLEASES; RIBONUCLEOPROTEINS; RNA; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA-BINDING PROTEINS; SUBSTRATE SPECIFICITY; TRANSCRIPTION FACTORS;

EID: 0035907317     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M010594200     Document Type: Article

References (51)

1. Hazelrigg, T. (1998) Cell 95, 451-460
2. Draper, D. E. (1995) Annu. Rev. Biochem. 64, 593-620
3. Siomi, H., and Dreyfuss, G. (1997) Curr. Opin. Gen. & Dev. 7, 345-353
4. Baer, B. W., and Kornberg, R. D. (1983) J. Cell Biol. 96, 717-721
5. Binder, R., Horowitz, J. A., Basilion, J. P., Koeller, D. M., Klausner, R. D., and Harford, J. B. (1994) EMBO J. 13, 1969-1980
6. Mullner, E. W., and Kuhn, L. C. (1988) Cell 53, 815-825
7. Zamore, P. D., Williamson, J. R., and Lehmann, R. (1997) RNA (NY) 3, 1421-1433
8. Zapp, M. L., and Green, M. R. (1989) Nature 342, 714-716
9. Zhang, B., Gallegos, M., Puoti, A., Durkin, E., Fields, S., Kimble, J., and Wickens, M. P. (1997) Nature 390, 477-484
10. McCarthy, J. E., and Kollmus, H. (1995) Trends Biochem. Sci. 20, 191-197
11. Rouault, T. A., and Harford, J. B. (1993) Cell 72, 19-28
12. Yang, Y. Y., Yin, G. L., and Darnell, R. B. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 13254-13259
13. Hughson, F. M., and Schedl, P. (1999) Nat. Struct. Biol. 6, 499-502
14. Burd, C. G., and Dreyfuss, G. (1994) Science 265, 615-621
15. Wittekind, M., Gorlach, M., Friedrichs, M., Dreyfuss, G., and Mueller, L. (1992) Biochemistry 31, 6254-6265
16. Ghisolfi, L., Joseph, G., Amalric, F., and Erard, M. (1992) J. Biol. Chem. 267, 2955-2959
17. Kim, C. A., and Berg, J. M. (1996) Nat. Struct. Biol. 3, 940-945
18. Kanamori, H., Dodson, R. E., and Shapiro, D. J. (1998) Mol. Cell. Biol. 18, 3991-4003
19. Siomi, H., Matunis, M. J., Michael, W. M., and Dreyfuss, G. (1993) Nucleic Acids Res. 21, 1193-1198
20. Berglund, J. A., Fleming, M. L., and Rosbash, M. (1998) RNA (NY) 4, 998-1006
21. Makeyev, A. V., and Liebhaber, S. A. (2000) Genomics 67, 301-316
22. Baber, J. L., Libutti, D., Levens, D., and Tjandra, N. (1999) J. Mol. Biol. 289, 949-962
23. Lewis, H. A., Chen, H., Edo, C., Buckanovich, R. J., Yang, Y. Y. L., Musunuru, K., Zhong, R., Darnell, R. B., and Burley, S. K. (1999) Structure 7, 191-203
24. Lewis, H. A., Musunuru, K., Jensen, K. B., Edo, C., Chen, H., Darnell, R. B., and Burley, S. K. (2000) Cell 100, 323-332
25. Musco, G., Stier, G., Joseph, C., Morelli, M. A., Nilges, M., Gibson, T. J., and Pastore, A. (1996) Cell 85, 237-245
26. Ostareck-Lederer, A., Ostareck, D., and Hentze, M. W. (1998) Trends Biochem. Sci. 23, 409-411
27. Ostareck, D. H., Ostareck-Lederer, A., Wilm, M., Thiele, B. J., Mann, M., and Hentze, M. W. (1997) Cell 89, 597-606
28. Leffers, H., Deigaard, K., and Celis, J. E. (1995) Eur. J. Biochem. 230, 447-453
29. Makeyev, A. V., Chkheidze, A. N., and Liebhaber, S. A. (1999) J. Biol. Chem. 274, 24849-24857
30. Chkheidze, A. N., Lyakhov, D. L., Makeyev, A. V., Morales, J., Kong, J., and Liebhaber, S. A. (1999) Mol. Cell. Biol. 19, 4572-4581
31. Kiledjian, M., Wang, X., and Liebhaber, S. A. (1995) EMBO J. 14, 4357-4364
32. Wang, X., Kiledjian, M., Weiss, I. M., and Liebhaber, S. A. (1995) Mol. Cell. Biol. 15, 1769-1777
33. Weiss, I. M., and Liebhaber, S. A. (1995) Mol. Cell. Biol. 15, 2457-2465
34. Holcik, M., and Liebhaber, S. A. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 2410-2414
35. Stefanovic, B., Hellerbrand, C., Holcik, M., Briendl, M., Liebhaber, S. A., and Brenner, D. A. (1997) Mol. Cell. Biol. 17, 5201-5209
36. Czyzyk-Krzeska, M. F., and Beresh, J. E. (1996) J. Biol. Chem. 271, 3293-3299
37. Ostareck-Lederer, A., Ostareck, D. H., Standart, N., and Thiele, B. J. (1994) EMBO J. 13, 1476-1481
38. Gamarnik, A. V., and Andino, R. (1997) RNA (NY) 3, 882-892
39. Silvera, D., Gamarnik, A. V., and Andino, R. (1999) J. Biol. Chem. 274, 38163-38170
40. Walter, B. L., Nguyen, J. H. C., Ehrenfeld, E., and Semler, B. L. (1999) RNA (NY) 5, 1570-1585
41. Gamarnik, A. V., and Andino, R. (1998) Genes Dev. 12, 2293-2304
42. Collier, B., Goobar-Larsson, L., Sokolowski, M., and Schwartz, S. (1998) J. Biol. Chem. 273, 22648-22656
43. Graff, J., Cha, J., Blyn, L. B., and Ehrenfeld, E. (1998) J. Virol. 72, 9668-9675
44. Spangberg, K., and Schwartz, S. (1999) J. Gen. Virol. 80, 1371-1376
45. Paillard, L., Maniey, D., Lachaume, P., Legagneux, V., and Osborne, H. B. (2000) Mech. Dev. 93, 117-125
46. Tuerk, C., and Gold, L. (1990) Science 249, 505-510
47. Tuerk, C., MacDougal, S., and Gold, L. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 6988-6992
48. Thisted, T., Sorensen, N. S., Wagner, E. G. H., and Gerdes, K. (1994) EMBO J. 13, 1960-1968
49. Mathews, D. H., Sabina, J., Zucker, M., and Turner, D. H. (1999) J. Mol. Biol. 288, 911-940
50. Zucker, M., Mathews, D. H., and Turner, D. H. (1999) in RNA Biochemistry and Bio/Technology (Barciszewski, J., and B. F. C. C., Clark, ed) pp. 11-43, NATO ASI Series, Kluwer Academic Publishers, Dordrecht, Illinois
51. Buckanovich, R. J., and Darnell, R. B. (1997) Mol. Cell. Biol. 17, 3194-3201