메뉴 건너뛰기




Volumn 120, Issue 4, 2009, Pages 235-241

Effect of high-dose methylprednisolone treatment on Th17 cells in patients with multiple sclerosis in relapse

Author keywords

Glucocorticoids; IL 17; IL 23R; Multiple sclerosis; RORc; Th17 cells

Indexed keywords

INTERLEUKIN 17; INTERLEUKIN 23 RECEPTOR; MESSENGER RNA; METHYLPREDNISOLONE;

EID: 70349251833     PISSN: 00016314     EISSN: 16000404     Source Type: Journal    
DOI: 10.1111/j.1600-0404.2009.01158.x     Document Type: Article
Times cited : (32)

References (36)
  • 1
    • 75749120039 scopus 로고    scopus 로고
    • Characteristic imprint of single nucleotide polymorphisms in multiple sclerosis
    • Sep 3 [epub ahead of print].
    • Szolnoki Z, Kondacs A, Mandi Y, Somogyvari F. Characteristic imprint of single nucleotide polymorphisms in multiple sclerosis. J Mol Neurosci 2008 Sep 3 [epub ahead of print].
    • (2008) J Mol Neurosci
    • Szolnoki, Z.1    Kondacs, A.2    Mandi, Y.3    Somogyvari, F.4
  • 2
    • 36949034307 scopus 로고    scopus 로고
    • A cytoskeleton motor protein genetic variant may exert a protective effect on the occurrence of multiple sclerosis: The janus face of the kinesin light-chain 1
    • 56836CC genetic variant.
    • Szolnoki Z, Kondacs A, Mandi Y, Somogyvari F. A cytoskeleton motor protein genetic variant may exert a protective effect on the occurrence of multiple sclerosis: the janus face of the kinesin light-chain 1 56836CC genetic variant. Neuromol Med 2007 9 : 335 339.
    • (2007) Neuromol Med , vol.9 , pp. 335-339
    • Szolnoki, Z.1    Kondacs, A.2    Mandi, Y.3    Somogyvari, F.4
  • 4
    • 27544490377 scopus 로고    scopus 로고
    • Interleukin 17-producing CD4(+) effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
    • Harrington LE, Hatton RD, Mangan PR et al. Interleukin 17-producing CD4(+) effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol 2005 6 : 1123 1132.
    • (2005) Nat Immunol , vol.6 , pp. 1123-1132
    • Harrington, L.E.1    Hatton, R.D.2    Mangan, P.R.3
  • 5
    • 33748588423 scopus 로고    scopus 로고
    • The orphan nuclear receptor ROR gammat directs the differentiation program of proinflammatory IL-17+ T helper cells
    • Ivanov II, McKenzie BS, Zhou L et al. The orphan nuclear receptor ROR gammat directs the differentiation program of proinflammatory IL-17+ T helper cells. Cell 2006 126 : 1121 1133.
    • (2006) Cell , vol.126 , pp. 1121-1133
    • Ivanov, I.I.1    McKenzie, B.S.2    Zhou, L.3
  • 6
    • 13244283212 scopus 로고    scopus 로고
    • IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
    • Langrish CL, Chen Y, Blumenschein WM et al. IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J Exp Med 2005 201 : 233 240.
    • (2005) J Exp Med , vol.201 , pp. 233-240
    • Langrish, C.L.1    Chen, Y.2    Blumenschein, W.M.3
  • 7
    • 34548133583 scopus 로고    scopus 로고
    • Development, cytokine profile and function of human interleukin 17-producing helper T cells
    • Wilson NJ, Boniface K, Chan JR et al. Development, cytokine profile and function of human interleukin 17-producing helper T cells. Nat Immunol 2007 8 : 950 957.
    • (2007) Nat Immunol , vol.8 , pp. 950-957
    • Wilson, N.J.1    Boniface, K.2    Chan, J.R.3
  • 11
    • 22144496795 scopus 로고    scopus 로고
    • The mechanism of action of methylprednisolone in the treatment of multiple sclerosis
    • Sloka JS, Stefanelli M. The mechanism of action of methylprednisolone in the treatment of multiple sclerosis. Mult Scler 2005 11 : 425 432.
    • (2005) Mult Scler , vol.11 , pp. 425-432
    • Sloka, J.S.1    Stefanelli, M.2
  • 12
    • 55949104126 scopus 로고    scopus 로고
    • The effects of methylprednisolone and mitoxantrone on CCL5-induced migration of lymphocytes in multiple sclerosis
    • Jalosinski M, Karolczak K, Mazurek A, Glabinski A. The effects of methylprednisolone and mitoxantrone on CCL5-induced migration of lymphocytes in multiple sclerosis. Acta Neurol Scand 2008 118 : 120 125.
    • (2008) Acta Neurol Scand , vol.118 , pp. 120-125
    • Jalosinski, M.1    Karolczak, K.2    Mazurek, A.3    Glabinski, A.4
  • 13
    • 69449104369 scopus 로고    scopus 로고
    • + CD25 high cell percentage and Foxp3 expression in patients with multiple sclerosis
    • Aug 22 [epub ahead of print].
    • + CD25 high cell percentage and Foxp3 expression in patients with multiple sclerosis. Acta Neurol Scand 2008 Aug 22 [epub ahead of print].
    • (2008) Acta Neurol Scand
    • Braitch, M.1    Harikrishnan, S.2    Robins, R.A.3
  • 14
    • 0034465872 scopus 로고    scopus 로고
    • Immunological effects of oral high-dose methylprednisolone in acute optic neuritis and multiple sclerosis
    • Sellebjerg F, Christiansen M, Jensen J, Frederiksen JL. Immunological effects of oral high-dose methylprednisolone in acute optic neuritis and multiple sclerosis. Eur J Neurol 2000 7 : 281 289.
    • (2000) Eur J Neurol , vol.7 , pp. 281-289
    • Sellebjerg, F.1    Christiansen, M.2    Jensen, J.3    Frederiksen, J.L.4
  • 15
    • 33746210026 scopus 로고    scopus 로고
    • Circulating dendritic cells subsets and regulatory T-cells at multiple sclerosis relapse: Differential short-term changes on corticosteroids therapy
    • Navarro J, Aristimuño C, Sánchez-Ramón S et al. Circulating dendritic cells subsets and regulatory T-cells at multiple sclerosis relapse: differential short-term changes on corticosteroids therapy. J Neuroimmunol 2006 176 : 153 161.
    • (2006) J Neuroimmunol , vol.176 , pp. 153-161
    • Navarro, J.1    Aristimuño, C.2    Sánchez-Ramón, S.3
  • 16
    • 0034955141 scopus 로고    scopus 로고
    • Recommended diagnostic criteria for multiple sclerosis: Guidelines from the International Panel on the diagnosis of multiple sclerosis
    • McDonald WI, Compston A, Edan G et al. Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the diagnosis of multiple sclerosis. Ann Neurol 2001 50 : 121 127.
    • (2001) Ann Neurol , vol.50 , pp. 121-127
    • McDonald, W.I.1    Compston, A.2    Edan, G.3
  • 18
    • 0038627491 scopus 로고    scopus 로고
    • Evidence for cytokine dysregulation in multiple sclerosis: Peripheral blood mononuclear cell production of pro-inflammatory and anti-inflammatory cytokines during relapse and remission
    • Hollifield RD, Harbige LS, Pham-Dinh D, Sharief MK. Evidence for cytokine dysregulation in multiple sclerosis: peripheral blood mononuclear cell production of pro-inflammatory and anti-inflammatory cytokines during relapse and remission. Autoimmunity 2003 36 : 133 141.
    • (2003) Autoimmunity , vol.36 , pp. 133-141
    • Hollifield, R.D.1    Harbige, L.S.2    Pham-Dinh, D.3    Sharief, M.K.4
  • 19
    • 3042749817 scopus 로고    scopus 로고
    • Glucocorticoids and the Th1, Th2 balance
    • Elenkov IJ. Glucocorticoids and the Th1, Th2 balance. Ann N Y Acad Sci 2004 1024 : 138 146.
    • (2004) Ann N y Acad Sci , vol.1024 , pp. 138-146
    • Elenkov, I.J.1
  • 20
    • 33846966636 scopus 로고    scopus 로고
    • A brief history of TH17, the first major revision in the TH1/TH2 hypothesis of T cell-mediated tissue damage
    • Steinman L. A brief history of TH17, the first major revision in the TH1/TH2 hypothesis of T cell-mediated tissue damage. Nat Med 2007 13 : 139 145.
    • (2007) Nat Med , vol.13 , pp. 139-145
    • Steinman, L.1
  • 21
    • 39449087338 scopus 로고    scopus 로고
    • Th17 cells: Effector T cells with inflammatory properties
    • Korn T, Oukka M, Kuchroo V, Bettelli E. Th17 cells: effector T cells with inflammatory properties. Semin Immunol 2007 19 : 362 371.
    • (2007) Semin Immunol , vol.19 , pp. 362-371
    • Korn, T.1    Oukka, M.2    Kuchroo, V.3    Bettelli, E.4
  • 22
    • 0036105484 scopus 로고    scopus 로고
    • Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis
    • Lock C, Hermans G, Pedotti R et al. Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis. Nat Med 2002 8 : 500 508.
    • (2002) Nat Med , vol.8 , pp. 500-508
    • Lock, C.1    Hermans, G.2    Pedotti, R.3
  • 23
    • 0344389016 scopus 로고    scopus 로고
    • Interleukin-17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosis
    • Matusevicius D, Kivisäkk P, He B et al. Interleukin-17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosis. Mult Scler 1999 5 : 101 104.
    • (1999) Mult Scler , vol.5 , pp. 101-104
    • Matusevicius, D.1    Kivisäkk, P.2    He, B.3
  • 24
    • 0037841704 scopus 로고    scopus 로고
    • Airway remodeling-associated mediators in moderate to severe asthma: Effect of steroids on TGF-β, IL-11, IL-17, and type i and type III collagen expression
    • Chakir J, Shannon J, Molet S et al. Airway remodeling-associated mediators in moderate to severe asthma: effect of steroids on TGF-β, IL-11, IL-17, and type I and type III collagen expression. J Allergy Clin Immunol 2003 111 : 1293 1298.
    • (2003) J Allergy Clin Immunol , vol.111 , pp. 1293-1298
    • Chakir, J.1    Shannon, J.2    Molet, S.3
  • 25
    • 50649113106 scopus 로고    scopus 로고
    • Methylprednisolone inhibits interleukin-17 and interferon-gamma expression by both naive and primed T cells
    • Momcilović M, Miljković Z, Popadić D et al. Methylprednisolone inhibits interleukin-17 and interferon-gamma expression by both naive and primed T cells. BMC Immunol 2008 9 : 47.
    • (2008) BMC Immunol , vol.9 , pp. 47
    • Momcilović, M.1    Miljković, Z.2    Popadić, D.3
  • 26
    • 50949102041 scopus 로고    scopus 로고
    • Peripheral T cells are the therapeutic targets of glucocorticoids in experimental autoimmune encephalomyelitis
    • Wüst S, van den Brandt J, Tischner D et al. Peripheral T cells are the therapeutic targets of glucocorticoids in experimental autoimmune encephalomyelitis. J Immunol 2008 180 : 8434 8443.
    • (2008) J Immunol , vol.180 , pp. 8434-8443
    • Wüst, S.1    Van Den Brandt, J.2    Tischner, D.3
  • 27
    • 41549153318 scopus 로고    scopus 로고
    • + regulatory T cells (TREG) in systemic lupus erythematosus (SLE) patients: The possible influence of treatment with corticosteroids
    • + regulatory T cells (TREG) in systemic lupus erythematosus (SLE) patients: the possible influence of treatment with corticosteroids. Clin Immunol 2008 127 : 151 157.
    • (2008) Clin Immunol , vol.127 , pp. 151-157
    • Azab, N.A.1    Bassyouni, I.H.2    Emad, Y.3    Abd El-Wahab, G.A.4    Hamdy, G.5    Mashahit, M.A.6
  • 28
    • 34548595302 scopus 로고    scopus 로고
    • Circulating dendritic cells subsets and CD4+ Foxp3+ regulatory T cells in adult patients with chronic ITP before and after treatment with high-dose dexamethasome
    • Ling Y, Cao X, Yu Z, Ruan C. Circulating dendritic cells subsets and CD4+ Foxp3+ regulatory T cells in adult patients with chronic ITP before and after treatment with high-dose dexamethasome. Eur J Haematol 2007 79 : 310 316.
    • (2007) Eur J Haematol , vol.79 , pp. 310-316
    • Ling, Y.1    Cao, X.2    Yu, Z.3    Ruan, C.4
  • 29
    • 20844432359 scopus 로고    scopus 로고
    • Glucocorticoids upregulate FOXP3 expression and regulatory T cells in asthma
    • Karagiannidis C, Akdis M, Holopainen P et al. Glucocorticoids upregulate FOXP3 expression and regulatory T cells in asthma. J Allergy Clin Immunol 2004 114 : 1425 1433.
    • (2004) J Allergy Clin Immunol , vol.114 , pp. 1425-1433
    • Karagiannidis, C.1    Akdis, M.2    Holopainen, P.3
  • 30
    • 33847667225 scopus 로고    scopus 로고
    • The role of T helper 17 (Th17) and regulatory T cells (Treg) in human organ transplantation and autoimmune disease
    • Afzali B, Lombardi G, Lechler RI, Lord GM. The role of T helper 17 (Th17) and regulatory T cells (Treg) in human organ transplantation and autoimmune disease. Clin Exp Immunol 2007 148 : 32 46.
    • (2007) Clin Exp Immunol , vol.148 , pp. 32-46
    • Afzali, B.1    Lombardi, G.2    Lechler, R.I.3    Lord, G.M.4
  • 31
    • 34848821989 scopus 로고    scopus 로고
    • Distinct regulation of interleukin-17 in human T helper lymphocytes
    • Chen Z, Tato CM, Muul L, Laurence A, O'Shea JJ. Distinct regulation of interleukin-17 in human T helper lymphocytes. Arthritis Rheum 2007 56 : 2936 2946.
    • (2007) Arthritis Rheum , vol.56 , pp. 2936-2946
    • Chen, Z.1    Tato, C.M.2    Muul, L.3    Laurence, A.4    O'Shea, J.J.5
  • 32
    • 39449101603 scopus 로고    scopus 로고
    • Transcriptional regulation of Th17 cell differentiation
    • Ivanov II, Zhou L, Littman DR. Transcriptional regulation of Th17 cell differentiation. Semin Immunol 2007 19 : 409 417.
    • (2007) Semin Immunol , vol.19 , pp. 409-417
    • Ivanov, I.I.1    Zhou, L.2    Littman, D.R.3
  • 33
    • 34248572345 scopus 로고    scopus 로고
    • TH-17 cells in the circle of immunity and autoimmunity
    • Bettelli E, Oukka M, Kuchroo VK. TH-17 cells in the circle of immunity and autoimmunity. Nat Immunol 2007 8 : 345 350.
    • (2007) Nat Immunol , vol.8 , pp. 345-350
    • Bettelli, E.1    Oukka, M.2    Kuchroo, V.K.3
  • 34
    • 0032529844 scopus 로고    scopus 로고
    • Prostaglandin E2 and dexamethasone inhibit IL-12 receptor expression and IL-12 responsiveness
    • Wu CY, Wang K, McDyer JF, Seder RA. Prostaglandin E2 and dexamethasone inhibit IL-12 receptor expression and IL-12 responsiveness. J Immunol 1998 161 : 2723 2730.
    • (1998) J Immunol , vol.161 , pp. 2723-2730
    • Wu, C.Y.1    Wang, K.2    McDyer, J.F.3    Seder, R.A.4
  • 35
    • 0035175408 scopus 로고    scopus 로고
    • High dose methylprednisolone therapy in multiple sclerosis induces apoptosis in peripheral blood leukocytes
    • Leussink VI, Jung S, Merschdorf U, Toyka KV, Gold R. High dose methylprednisolone therapy in multiple sclerosis induces apoptosis in peripheral blood leukocytes. Arch Neurol 2001 58 : 91 7.
    • (2001) Arch Neurol , vol.58 , pp. 91-7
    • Leussink, V.I.1    Jung, S.2    Merschdorf, U.3    Toyka, K.V.4    Gold, R.5
  • 36
    • 0036175298 scopus 로고    scopus 로고
    • Treatment with methylprednisolone in relapses of multiple sclerosis patients: Immunological evidence of immediate and short-term but not long-lasting effects
    • Martínez-Cáceres EM, Barrau MA, Brieva L, Espejo C, Barberà N, Montalban X. Treatment with methylprednisolone in relapses of multiple sclerosis patients: immunological evidence of immediate and short-term but not long-lasting effects. Clin Exp Immunol 2002 127 : 165 171.
    • (2002) Clin Exp Immunol , vol.127 , pp. 165-171
    • Martínez-Cáceres, E.M.1    Barrau, M.A.2    Brieva, L.3    Espejo, C.4    Barberà, N.5    Montalban, X.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.