Positively charged retinoids are potent and selective inhibitors of the trans-cis isomerization in the retinoid (visual) cycle

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 23, 2005, Pages 8162-8167

  Golczak, Marcin ^a   Kuksa, Vladimir ^a   Maeda, Tadao ^a   Moise, Alexander R ^a   Palczewski, Krzysztof ^a,b  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Electroretinogram; Retinal; Retinal pigment epithelium; Rhodopsin; Vitamin A

Indexed keywords

11 CIS RETINAL; RETINAL; RETINOIC ACID; RETINOIC ACID RECEPTOR; RETINOID; RETINOID X RECEPTOR; RETINYLAMINE; UNCLASSIFIED DRUG;

ADOLESCENT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHROMATOPHORE; CIS TRANS ISOMERISM; ELECTRORETINOGRAM; ISOMERIZATION; MOUSE; NONHUMAN; PHOTORECEPTOR; PHOTOTRANSDUCTION; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN BINDING; RECEPTOR UPREGULATION; REGENERATION; RETINA CONE; RETINA ROD; VISION;

ANIMALS; CHROMATOGRAPHY, GEL; CIS-TRANS-ISOMERASES; CYTOCHROME P-450 ENZYME SYSTEM; DITERPENES; ELECTROSTATICS; ISOMERISM; MICE; PHOTORECEPTORS, VERTEBRATE; PHOTOTRANSDUCTION; RECEPTORS, RETINOIC ACID; RETINOID X RECEPTORS; RETINOIDS; SENSITIVITY AND SPECIFICITY; SUBSTRATE SPECIFICITY; VITAMIN A;

VERTEBRATA;

EID: 20444406091     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0503318102     Document Type: Article

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