Expression of Nov, CYR61 and CTGF genes in human hepatocellular carcinoma

Hepatology Research

Volumn 19, Issue 3, 2001, Pages 294-305

  Hirasaki, Shoji ^a   Koide, Norio ^a   Ujike, Kozo ^a   Shinji, Toshiyuki ^a   Tsuji, Takao ^a  

^a OKAYAMA UNIVERSITY   (Japan)

Author keywords

Gene expression; Immediate early gene; Metastatic liver cancer; Reverse transcription polymerase chain reaction

Indexed keywords

CONNECTIVE TISSUE GROWTH FACTOR; MESSENGER RNA; PROTEIN CYR 61; PROTEIN NOV; RNA; SOMATOMEDIN BINDING PROTEIN; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CARCINOGENESIS; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION FUNCTION; FEMALE; FIBROBLAST; GENE EXPRESSION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMEDIATE EARLY GENE; LIVER BIOPSY; LIVER CELL CARCINOMA; LIVER METASTASIS; MALE; MULTIGENE FAMILY; NEPHROBLASTOMA; PARAMETER; PREVALENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ANALYSIS;

EID: 0035081385     PISSN: 13866346     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1386-6346(00)00101-7     Document Type: Article

References (20)

1. Proviral rearrangements and overexpression of a new cellular gene (nov) in myeloblastosis-associated virus type 1-induced nephroblastomas
2. Structural analysis of the human nov proto-oncogene and expression in Wilms tumors
3. Expression of the growth factor-inducible immediate early gene cyr61 correlates with chondrogenesis during mouse embryonic development
4. CYR-61, a product of a growth factor-inducible immediate early gene, promotes angiogenesis and tumor growth
5. Connective tissue growth factor: A cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10
6. Identification of rCop-1, a new member of the CCN protein family, as a negative regulator for cell transformation
7. Expression of the Elm1 gene, a novel gene of the CCN (connective tissue growth factor, Cyr61/Cef10, and neuroblastoma overexpressed gene) family, suppresses in vivo tumor growth and metastasis of K-1735 murinemelanoma cells
8. Cyr61 and Fisp 12 are both ECM-associated signaling molecules: Activities, metabolism, and localization during development
9. The C-terminal domain of the regulatory protein NOVH is sufficient to promote interaction with fibulin 1C: A clue for a role of NOVH in cell-adhesion signaling
10. A method for isolation of intact, transrationally active ribonucleic acid
11. Transcriptional down regulation of the nov proto-oncogene in fibroblasts transformed by p60v-src
12. Identification of a phorbol ester-repressible v-src-inducible gene
13. Expression of CYR-61, a growth factor-inducible immediate-early gene
14. Structure, mapping, and expression of fisp-12, a growth factor-inducible gene encoding a secreted cysteine-rich protein
15. Nephroblastoma overexpressed gene (Nov) codes for a growth factor that induces protein tyrosine phosphorylation
16. Regulation of connective tissue growth factor gene expression in human skin fibroblasts and during wound repair
17. Significant correlation between CTGF gene expression and skin sclerosis in tissue sections from patients with systemic sclerosis