메뉴 건너뛰기




Volumn 4, Issue 2, 2009, Pages 177-184

Pathogenesis of the H5N1 avian influenza virus in humans and mammalian models

Author keywords

Apoptosis; Avian influenza; Cytokine; Genetic determinants; H5N1; Hemagglutinin; Human; Mammalian; Pathology; Virulence

Indexed keywords

CHEMOKINE RECEPTOR CXCR3; HEMAGGLUTININ; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA; VIRUS RECEPTOR;

EID: 70349204519     PISSN: 17460794     EISSN: None     Source Type: Journal    
DOI: 10.2217/17460794.4.2.177     Document Type: Review
Times cited : (3)

References (98)
  • 1
    • 0033602713 scopus 로고    scopus 로고
    • Role of hemagglutinin cleavage for the pathogenicity of influenza virus
    • Steinhauer DA: Role of hemagglutinin cleavage for the pathogenicity of influenza virus. Virology 258, 1-20 (1999).
    • (1999) Virology , vol.258 , pp. 1-20
    • Steinhauer, D.A.1
  • 2
    • 0037038866 scopus 로고    scopus 로고
    • Induction of proinflammatory cytokines in human macrophages by influenza A (H5N1) viruses: A mechanism for the unusual severity of human disease?
    • Cheung CY, Poon LL, Lau AS et al.: Induction of proinflammatory cytokines in human macrophages by influenza A (H5N1) viruses: a mechanism for the unusual severity of human disease? Lancet 360, 1831-1837 (2002).
    • (2002) Lancet , vol.360 , pp. 1831-1837
    • Cheung, C.Y.1    Poon, L.L.2    Lau, A.S.3
  • 3
    • 0036734038 scopus 로고    scopus 로고
    • Lethal H5N1 influenza viruses escape host antiviral cytokine responses
    • Seo SH, Hoffmann E, Webster RG: Lethal H5N1 influenza viruses escape host antiviral cytokine responses. Nat. Med. 8, 950-954 (2002).
    • (2002) Nat. Med , vol.8 , pp. 950-954
    • Seo, S.H.1    Hoffmann, E.2    Webster, R.G.3
  • 4
    • 2442446901 scopus 로고    scopus 로고
    • The NS1 gene of H5N1 influenza viruses circumvents the host antiviral cytokine responses
    • Seo SH, Hoffmann E, Webster RG: The NS1 gene of H5N1 influenza viruses circumvents the host antiviral cytokine responses. Virus Res. 103, 107-113 (2004).
    • (2004) Virus Res , vol.103 , pp. 107-113
    • Seo, S.H.1    Hoffmann, E.2    Webster, R.G.3
  • 6
    • 55549097119 scopus 로고    scopus 로고
    • H5N1 avian influenza virus induces apoptotic cell death in mammalian airway epithelial cells
    • Daidoji T, Koma T, Du A et al.: H5N1 avian influenza virus induces apoptotic cell death in mammalian airway epithelial cells. J. Virol. 82, 11294-11307 (2008).
    • (2008) J. Virol , vol.82 , pp. 11294-11307
    • Daidoji, T.1    Koma, T.2    Du, A.3
  • 7
    • 34247897134 scopus 로고    scopus 로고
    • Apoptosis and pathogenesis of avian influenza A (H5N1) virus in humans
    • Uiprasertkul M, Kitphati R, Puthavathana P et al.: Apoptosis and pathogenesis of avian influenza A (H5N1) virus in humans. Emerg. Infect. Dis. 13, 708-712 (2007).
    • (2007) Emerg. Infect. Dis , vol.13 , pp. 708-712
    • Uiprasertkul, M.1    Kitphati, R.2    Puthavathana, P.3
  • 8
    • 33645332877 scopus 로고    scopus 로고
    • Functional tumor necrosis factor-related apoptosis-inclucing ligand production by avian influenza virus-infected macrophages
    • Zhou J, Law HK, Cheung CY, Ng IH, Peiris JS, Lau YL: Functional tumor necrosis factor-related apoptosis-inclucing ligand production by avian influenza virus-infected macrophages. J. Infect. Dis. 193, 945-953 (2006).
    • (2006) J. Infect. Dis , vol.193 , pp. 945-953
    • Zhou, J.1    Law, H.K.2    Cheung, C.Y.3    Ng, I.H.4    Peiris, J.S.5    Lau, Y.L.6
  • 12
    • 0023752476 scopus 로고
    • Lessons for human influenza from pathogenicity studies with ferrets
    • Smith H, Sweet C: Lessons for human influenza from pathogenicity studies with ferrets. Rev. Infect. Dis. 10, 56-75 (1988).
    • (1988) Rev. Infect. Dis , vol.10 , pp. 56-75
    • Smith, H.1    Sweet, C.2
  • 13
    • 0028839403 scopus 로고
    • Receptor specificity of influenza virus influences severity of illness in ferrets
    • Leigh MW, Connor RJ, Kelm S, Baum LG, Paulson JC: Receptor specificity of influenza virus influences severity of illness in ferrets. Vaccine 13, 1468-1473 (1995).
    • (1995) Vaccine , vol.13 , pp. 1468-1473
    • Leigh, M.W.1    Connor, R.J.2    Kelm, S.3    Baum, L.G.4    Paulson, J.C.5
  • 14
    • 13444292912 scopus 로고    scopus 로고
    • Lethality to ferrets of H5N1 influenza viruses isolated from humans and poultry in 2004
    • Govorkova EA, Rehg JE, Krauss S et al.: Lethality to ferrets of H5N1 influenza viruses isolated from humans and poultry in 2004. J. Virol. 79, 2191-2198 (2005).
    • (2005) J. Virol , vol.79 , pp. 2191-2198
    • Govorkova, E.A.1    Rehg, J.E.2    Krauss, S.3
  • 16
    • 34250829563 scopus 로고    scopus 로고
    • Inefficient transmission of H5N1 influenza viruses in a ferret contact model
    • Yen HL, Lipatov AS, Ilyushina NA et al.: Inefficient transmission of H5N1 influenza viruses in a ferret contact model. J. Virol. 81, 6896-6898 (2007).
    • (2007) J. Virol , vol.81 , pp. 6896-6898
    • Yen, H.L.1    Lipatov, A.S.2    Ilyushina, N.A.3
  • 17
    • 33747031407 scopus 로고    scopus 로고
    • Lack, of transmission of H5N1 avian-human reassortant influenza viruses in a ferret model
    • Maines TR, Chen LM, Matsuoka Y et al.: Lack, of transmission of H5N1 avian-human reassortant influenza viruses in a ferret model. Proc. Natl. Acad. Sci. USA 103, 12121-12126 (2006).
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 12121-12126
    • Maines, T.R.1    Chen, L.M.2    Matsuoka, Y.3
  • 19
    • 0038486953 scopus 로고    scopus 로고
    • Pathology of human influenza A (H5N1) virus infection in cynomolgus macaques ( Macaca fascicularis)
    • Kuiken T, Rimmelzwaan GF, van Amerongen G, Osterhaus AD: Pathology of human influenza A (H5N1) virus infection in cynomolgus macaques ( Macaca fascicularis). Vet. Pathol. 40, 304-310 (2003).
    • (2003) Vet. Pathol , vol.40 , pp. 304-310
    • Kuiken, T.1    Rimmelzwaan, G.F.2    van Amerongen, G.3    Osterhaus, A.D.4
  • 21
    • 0037967934 scopus 로고    scopus 로고
    • Neurotropism of the 1997 Hong Kong H5N1 influenza virus in mice
    • Tanaka H, Park CH, Ninomiya A et al.: Neurotropism of the 1997 Hong Kong H5N1 influenza virus in mice. Vet. Microbiol. 95, 1-13 (2003).
    • (2003) Vet. Microbiol , vol.95 , pp. 1-13
    • Tanaka, H.1    Park, C.H.2    Ninomiya, A.3
  • 22
    • 0037334413 scopus 로고    scopus 로고
    • Neurovirulence in mice of H5N1 influenza virus genotypes isolated from Hong Kong poultry in 2001
    • Lipatov AS, Krauss S, Guan Y et al.: Neurovirulence in mice of H5N1 influenza virus genotypes isolated from Hong Kong poultry in 2001. J. Virol. 77, 3816-3823 (2003).
    • (2003) J. Virol , vol.77 , pp. 3816-3823
    • Lipatov, A.S.1    Krauss, S.2    Guan, Y.3
  • 23
    • 0141677633 scopus 로고    scopus 로고
    • Neurological manifestations of avian influenza viruses in mammals
    • Rowe T, Cho DS, Bright RA, Zitzow LA, Katz JM: Neurological manifestations of avian influenza viruses in mammals. Avian Dis. 47, 1122-1126 (2003).
    • (2003) Avian Dis , vol.47 , pp. 1122-1126
    • Rowe, T.1    Cho, D.S.2    Bright, R.A.3    Zitzow, L.A.4    Katz, J.M.5
  • 24
    • 0033804340 scopus 로고    scopus 로고
    • Characterization of human influenza A (H5N1) virus infection in mice: Neuro-, pneumo- and adipotropic infection
    • Nishimura H, Itamura S, Iwasaki T, Kurata T, Tashiro M: Characterization of human influenza A (H5N1) virus infection in mice: neuro-, pneumo- and adipotropic infection. J. Gen. Virol. 81, 2503-2510 (2000).
    • (2000) J. Gen. Virol , vol.81 , pp. 2503-2510
    • Nishimura, H.1    Itamura, S.2    Iwasaki, T.3    Kurata, T.4    Tashiro, M.5
  • 25
    • 33751438303 scopus 로고    scopus 로고
    • Recent H5N1 avian influenza A virus increases rapidly in virulence to mice after a single passage in mice
    • Mase M, Tanimura N, Imada T, Okamatsu M, Tsukamoto K, Yamaguchi S: Recent H5N1 avian influenza A virus increases rapidly in virulence to mice after a single passage in mice. J. Gen. Virol. 87, 3655-3659 (2006).
    • (2006) J. Gen. Virol , vol.87 , pp. 3655-3659
    • Mase, M.1    Tanimura, N.2    Imada, T.3    Okamatsu, M.4    Tsukamoto, K.5    Yamaguchi, S.6
  • 26
    • 24644503497 scopus 로고    scopus 로고
    • Avian influenza (H5N1) viruses isolated from humans in Asia in 2004 exhibit increased virulence in mammals
    • Maines TR, Lu XH, Erb SM et al.: Avian influenza (H5N1) viruses isolated from humans in Asia in 2004 exhibit increased virulence in mammals. J. Virol. 79, 11788-11800 (2005).
    • (2005) J. Virol , vol.79 , pp. 11788-11800
    • Maines, T.R.1    Lu, X.H.2    Erb, S.M.3
  • 27
    • 0035983249 scopus 로고    scopus 로고
    • The invasion routes of neurovirulent A/Hong Kong/483/97 (H5N1) influenza virus into the central nervous system after respiratory infection in mice
    • Park CH, Ishinaka M, Takada A et al.: The invasion routes of neurovirulent A/Hong Kong/483/97 (H5N1) influenza virus into the central nervous system after respiratory infection in mice. Arch. Virol. 147, 1425-1436 (2002).
    • (2002) Arch. Virol , vol.147 , pp. 1425-1436
    • Park, C.H.1    Ishinaka, M.2    Takada, A.3
  • 28
    • 8844261873 scopus 로고    scopus 로고
    • Productive infection in the murine central nervous system with avian influenza virus A (H5N1) after intranasal inoculation
    • Iwasaki T, Itamura S, Nishimura H et al.: Productive infection in the murine central nervous system with avian influenza virus A (H5N1) after intranasal inoculation. Acta Neuropathol. 108, 485-492 (2004).
    • (2004) Acta Neuropathol , vol.108 , pp. 485-492
    • Iwasaki, T.1    Itamura, S.2    Nishimura, H.3
  • 29
    • 33750535794 scopus 로고    scopus 로고
    • Fatal avian influenza A H5N1 in a dog
    • Songserm T, Amonsin A, Jamon R et al.: Fatal avian influenza A H5N1 in a dog. Emerg. Infect. Dis. 12, 1744-1747 (2006).
    • (2006) Emerg. Infect. Dis , vol.12 , pp. 1744-1747
    • Songserm, T.1    Amonsin, A.2    Jamon, R.3
  • 30
    • 45249117682 scopus 로고    scopus 로고
    • Transmission of avian influenza virus (H3N2) to dogs
    • Song D, Kang B, Lee C et al.: Transmission of avian influenza virus (H3N2) to dogs. Emerg. Infect. Dis. 14, 741-746 (2008).
    • (2008) Emerg. Infect. Dis , vol.14 , pp. 741-746
    • Song, D.1    Kang, B.2    Lee, C.3
  • 32
    • 23244441124 scopus 로고    scopus 로고
    • Studies of H5N1 influenza virus infection of pigs by using viruses isolated in Vietnam and Thailand in 2004
    • Choi YK, Nguyen TD, Ozaki H et al.: Studies of H5N1 influenza virus infection of pigs by using viruses isolated in Vietnam and Thailand in 2004. J. Virol. 79, 10821-10825 (2005).
    • (2005) J. Virol , vol.79 , pp. 10821-10825
    • Choi, Y.K.1    Nguyen, T.D.2    Ozaki, H.3
  • 33
    • 46349103284 scopus 로고    scopus 로고
    • Experimental infection of cattle with highly pathogenic avian influenza virus (H5N1)
    • Kalthoff D, Hoffmann B, Harder T, Durban M, Beer M: Experimental infection of cattle with highly pathogenic avian influenza virus (H5N1). Emerg. Infect. Dis. 14, 1132-1134 (2008).
    • (2008) Emerg. Infect. Dis , vol.14 , pp. 1132-1134
    • Kalthoff, D.1    Hoffmann, B.2    Harder, T.3    Durban, M.4    Beer, M.5
  • 34
    • 34648840650 scopus 로고    scopus 로고
    • H5N1 infection of the respiratory tract and beyond: A molecular pathology study
    • Gu J, Xie Z, Gao Z et al.: H5N1 infection of the respiratory tract and beyond: a molecular pathology study. Lancet 370, 1137-1145 (2007).
    • (2007) Lancet , vol.370 , pp. 1137-1145
    • Gu, J.1    Xie, Z.2    Gao, Z.3
  • 35
    • 43449131547 scopus 로고    scopus 로고
    • Pathology, molecular biology, and pathogenesis of avian influenza A (H5N1) infection in humans
    • Korteweg C, Gu J: Pathology, molecular biology, and pathogenesis of avian influenza A (H5N1) infection in humans. Am. J. Pathol. 172, 1155-1170 (2008).
    • (2008) Am. J. Pathol , vol.172 , pp. 1155-1170
    • Korteweg, C.1    Gu, J.2
  • 36
    • 0035140519 scopus 로고    scopus 로고
    • Pathology of fatal human infection associated with avian influenza A H5N1 virus
    • To KF, Chan PK, Chan KF et al.: Pathology of fatal human infection associated with avian influenza A H5N1 virus. J. Med. Virol. 63, 242-246 (2001).
    • (2001) J. Med. Virol , vol.63 , pp. 242-246
    • To, K.F.1    Chan, P.K.2    Chan, K.F.3
  • 37
    • 50849097044 scopus 로고    scopus 로고
    • Perrone LA, Plowden JK, Garcia-Sastre A, Katz JM, Tumpey TM: H5N1 and 1918 pandemic influenza virus infection results in early and excessive infiltration of macrophages and neutrophils in the lungs of mice. PLoS Pathog. 4, e1000115 (2008).
    • Perrone LA, Plowden JK, Garcia-Sastre A, Katz JM, Tumpey TM: H5N1 and 1918 pandemic influenza virus infection results in early and excessive infiltration of macrophages and neutrophils in the lungs of mice. PLoS Pathog. 4, e1000115 (2008).
  • 38
    • 38349068756 scopus 로고    scopus 로고
    • Update on avian influenza A (H5N1) virus infection in humans
    • Abdel-Ghafar AN, Chotpitayasunondh T, Gao Z et al.: Update on avian influenza A (H5N1) virus infection in humans. N. Engl. J. Med. 358, 261-273 (2008).
    • (2008) N. Engl. J. Med , vol.358 , pp. 261-273
    • Abdel-Ghafar, A.N.1    Chotpitayasunondh, T.2    Gao, Z.3
  • 40
    • 13744258437 scopus 로고    scopus 로고
    • Fatal avian influenza A (H5N1) in a child presenting with diarrhea followed by coma
    • de Jong MD, Bach VC, Phan TQ et al.: Fatal avian influenza A (H5N1) in a child presenting with diarrhea followed by coma. N. Engl. J. Med. 352, 686-691 (2005).
    • (2005) N. Engl. J. Med , vol.352 , pp. 686-691
    • de Jong, M.D.1    Bach, V.C.2    Phan, T.Q.3
  • 41
    • 0026643396 scopus 로고
    • Influenza virus hemagglutinin with multibasic cleavage site is activated by furin, a subtilisin-like endoprotease
    • Stieneke-Grober A, Vey M, Angliker H et al.: Influenza virus hemagglutinin with multibasic cleavage site is activated by furin, a subtilisin-like endoprotease. EMBO J. 11, 2407-2414 (1992).
    • (1992) EMBO J , vol.11 , pp. 2407-2414
    • Stieneke-Grober, A.1    Vey, M.2    Angliker, H.3
  • 42
    • 14444284599 scopus 로고    scopus 로고
    • Characterization of an avian influenza A (H5N1) virus isolated from a child with a fatal respiratory illness
    • Subbarao K, Klimov A, Katz J et al.: Characterization of an avian influenza A (H5N1) virus isolated from a child with a fatal respiratory illness. Science 279, 393-396 (1998).
    • (1998) Science , vol.279 , pp. 393-396
    • Subbarao, K.1    Klimov, A.2    Katz, J.3
  • 43
    • 0029383610 scopus 로고
    • Cleavability of hemagglutinin from an extremely virulent strain of avian influenza virus containing a unique cleavage site sequence
    • Horimoto T, Ito T, Alexander DJ, Kawaoka Y: Cleavability of hemagglutinin from an extremely virulent strain of avian influenza virus containing a unique cleavage site sequence. J. Vet. Med. Sci. 57, 927-930 (1995).
    • (1995) J. Vet. Med. Sci , vol.57 , pp. 927-930
    • Horimoto, T.1    Ito, T.2    Alexander, D.J.3    Kawaoka, Y.4
  • 44
    • 4444333308 scopus 로고    scopus 로고
    • Molecular determinants within the surface proteins involved in the pathogenicity of H5N1 influenza viruses in chickens
    • Hulse DJ, Webster RG, Russell RJ, Perez DR: Molecular determinants within the surface proteins involved in the pathogenicity of H5N1 influenza viruses in chickens. J. Virol. 78, 9954-9964 (2004).
    • (2004) J. Virol , vol.78 , pp. 9954-9964
    • Hulse, D.J.1    Webster, R.G.2    Russell, R.J.3    Perez, D.R.4
  • 46
    • 27744598497 scopus 로고    scopus 로고
    • Pathogenicity of influenza viruses with genes from the 1918 pandemic virus: Functional roles of alveolar macrophages and neutrophils in limiting virus replication and mortality in mice
    • Tumpey TM, Garcia-Sastre A, Taubenberger JK et al.: Pathogenicity of influenza viruses with genes from the 1918 pandemic virus: functional roles of alveolar macrophages and neutrophils in limiting virus replication and mortality in mice. J. Virol. 79, 14933-14944 (2005).
    • (2005) J. Virol , vol.79 , pp. 14933-14944
    • Tumpey, T.M.1    Garcia-Sastre, A.2    Taubenberger, J.K.3
  • 48
    • 34547780630 scopus 로고    scopus 로고
    • Polygenic virulence factors involved in pathogenesis of 1997 Hong Kong H5N1 influenza viruses in mice
    • Chen H, Bright RA, Subbarao K et al.: Polygenic virulence factors involved in pathogenesis of 1997 Hong Kong H5N1 influenza viruses in mice. Virus Res. 128, 159-163 (2007).
    • (2007) Virus Res , vol.128 , pp. 159-163
    • Chen, H.1    Bright, R.A.2    Subbarao, K.3
  • 49
    • 0033760939 scopus 로고    scopus 로고
    • Molecular correlates of influenza A H5N1 virus pathogenesis in mice
    • Katz JM, Lu X, Tumpey TM, Smith CB, Shaw MW, Subbarao K: Molecular correlates of influenza A H5N1 virus pathogenesis in mice. J. Virol. 74, 10807-10810 (2000).
    • (2000) J. Virol , vol.74 , pp. 10807-10810
    • Katz, J.M.1    Lu, X.2    Tumpey, T.M.3    Smith, C.B.4    Shaw, M.W.5    Subbarao, K.6
  • 50
    • 34547619982 scopus 로고    scopus 로고
    • Inhibition of the cytokine response does not protect against lethal H5N1 influenza infection
    • Salomon R, Hoffmann E, Webster RG: Inhibition of the cytokine response does not protect against lethal H5N1 influenza infection. Proc. Natl Acad. Sci. USA 104, 12479-12481 (2007).
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 12479-12481
    • Salomon, R.1    Hoffmann, E.2    Webster, R.G.3
  • 51
    • 56149106822 scopus 로고    scopus 로고
    • H5N1 transmission and disease: Observations from the frontlines
    • de Jong MD: H5N1 transmission and disease: observations from the frontlines. Pediatr. Infect. Dis. J. 27, S54-S56 (2008).
    • (2008) Pediatr. Infect. Dis. J , vol.27
    • de Jong, M.D.1
  • 52
    • 33749511112 scopus 로고    scopus 로고
    • Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia
    • de Jong MD, Simmons CP, Thanh TT et al.: Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia. Nat. Med. 12, 1203-1207 (2006).
    • (2006) Nat. Med , vol.12 , pp. 1203-1207
    • de Jong, M.D.1    Simmons, C.P.2    Thanh, T.T.3
  • 53
    • 33645058912 scopus 로고    scopus 로고
    • The polymerase complex genes contribute to the high virulence of the human H5N1 influenza virus isolate A/Vietnam/1203/04
    • Salomon R, Franks J, Govorkova EA et al.: The polymerase complex genes contribute to the high virulence of the human H5N1 influenza virus isolate A/Vietnam/1203/04, J. Exp. Med. 203, 689-697 (2006).
    • (2006) J. Exp. Med , vol.203 , pp. 689-697
    • Salomon, R.1    Franks, J.2    Govorkova, E.A.3
  • 54
    • 34247565021 scopus 로고    scopus 로고
    • Host-range determinants on the PB2 protein of influenza A viruses control the interaction between the viral polymerase and nucleoprotein in human cells
    • Labadie K, Dos Santos Afonso E, Rameix-Welti MA, van der Werf S, Naffakh N: Host-range determinants on the PB2 protein of influenza A viruses control the interaction between the viral polymerase and nucleoprotein in human cells. Virology 362, 271-282 (2007).
    • (2007) Virology , vol.362 , pp. 271-282
    • Labadie, K.1    Dos Santos Afonso, E.2    Rameix-Welti, M.A.3    van der Werf, S.4    Naffakh, N.5
  • 55
    • 0035823083 scopus 로고    scopus 로고
    • Molecular basis for high virulence of Hong Kong H5N1 influenza A viruses
    • Hatta M, Gao P, Halfmann P, Kawaoka Y: Molecular basis for high virulence of Hong Kong H5N1 influenza A viruses. Science 293, 1840-1842 (2001).
    • (2001) Science , vol.293 , pp. 1840-1842
    • Hatta, M.1    Gao, P.2    Halfmann, P.3    Kawaoka, Y.4
  • 56
    • 13644270916 scopus 로고    scopus 로고
    • Molecular characterization of the complete genome of human influenza H5N1 virus isolates from Thailand
    • Puthavathana P, Auewarakul P, Charoenying PC et al.: Molecular characterization of the complete genome of human influenza H5N1 virus isolates from Thailand. J. Gen. Virol. 86, 423-433 (2005).
    • (2005) J. Gen. Virol , vol.86 , pp. 423-433
    • Puthavathana, P.1    Auewarakul, P.2    Charoenying, P.C.3
  • 57
    • 0035026051 scopus 로고    scopus 로고
    • Residue 627 of PB2 is a determinant of cold sensitivity in RNA replication of avian influenza viruses
    • Massin P, van der Werf S, Naffakh N: Residue 627 of PB2 is a determinant of cold sensitivity in RNA replication of avian influenza viruses. J. Virol. 75, 5398-5404 (2001).
    • (2001) J. Virol , vol.75 , pp. 5398-5404
    • Massin, P.1    van der Werf, S.2    Naffakh, N.3
  • 58
    • 36049011840 scopus 로고    scopus 로고
    • Growth of H5N1 influenza A viruses in the upper respiratory tracts of mice
    • Hatta M, Hatta Y, Kim JH et al.: Growth of H5N1 influenza A viruses in the upper respiratory tracts of mice. PLoS Pathog. 3, 1374-1379 (2007).
    • (2007) PLoS Pathog , vol.3 , pp. 1374-1379
    • Hatta, M.1    Hatta, Y.2    Kim, J.H.3
  • 59
    • 0029797439 scopus 로고    scopus 로고
    • Sialic acids structure-analysis-metabolism-occurence-recognition
    • Reuter G, Gabius HJ: Sialic acids structure-analysis-metabolism-occurence-recognition. Biol. Chem. Hoppe-Seyler 377, 325-342 (1996).
    • (1996) Biol. Chem. Hoppe-Seyler , vol.377 , pp. 325-342
    • Reuter, G.1    Gabius, H.J.2
  • 60
    • 21144441367 scopus 로고    scopus 로고
    • Sialobiology of influenza: Molecular mechanism of host range variation of influenza viruses
    • Suzuki Y: Sialobiology of influenza: molecular mechanism of host range variation of influenza viruses. Biol. Pharm. Bull. 28, 399-408 (2005).
    • (2005) Biol. Pharm. Bull , vol.28 , pp. 399-408
    • Suzuki, Y.1
  • 61
    • 0020520729 scopus 로고
    • Receptor determinants of human and animal influenza virus isolates: Differences in receptor specificity of the H3 hemagglutinin based on species of origin
    • Rogers GN, Paulson JC: Receptor determinants of human and animal influenza virus isolates: differences in receptor specificity of the H3 hemagglutinin based on species of origin. Virology 127, 361-373 (1983).
    • (1983) Virology , vol.127 , pp. 361-373
    • Rogers, G.N.1    Paulson, J.C.2
  • 63
    • 0027302926 scopus 로고
    • Influenza virus strains selectively recognize sialyloligosaccharides on human respiratory epithelium; the role of the host cell in selection of hemagglutinin receptor specificity
    • Couceiro JN, Paulson JC, Baum LG: Influenza virus strains selectively recognize sialyloligosaccharides on human respiratory epithelium; the role of the host cell in selection of hemagglutinin receptor specificity. Virus Res. 29, 155-165 (1993).
    • (1993) Virus Res , vol.29 , pp. 155-165
    • Couceiro, J.N.1    Paulson, J.C.2    Baum, L.G.3
  • 64
    • 0348111446 scopus 로고    scopus 로고
    • Human-specific regulation of α2-6-linked sialic acids
    • Gagneux P, Cheriyan M, Hurtado-Ziola N et al.: Human-specific regulation of α2-6-linked sialic acids. J. Biol. Chem. 278, 48245-48250 (2003).
    • (2003) J. Biol. Chem , vol.278 , pp. 48245-48250
    • Gagneux, P.1    Cheriyan, M.2    Hurtado-Ziola, N.3
  • 65
  • 66
    • 40449131540 scopus 로고    scopus 로고
    • Avian influenza receptor expression in H5N1-infected and noninfected human tissues
    • Yao L, Korteweg C, Hsueh W, Gu J: Avian influenza receptor expression in H5N1-infected and noninfected human tissues. Faseb J. 22, 733-740 (2008).
    • (2008) Faseb J , vol.22 , pp. 733-740
    • Yao, L.1    Korteweg, C.2    Hsueh, W.3    Gu, J.4
  • 68
    • 13744252481 scopus 로고    scopus 로고
    • Lack of H5N1 avian influenza transmission to hospital employees, Hanoi, 2004
    • Liem NT, Lim W: Lack of H5N1 avian influenza transmission to hospital employees, Hanoi, 2004. Emerg. Infect. Dis. 11, 210-215 (2005).
    • (2005) Emerg. Infect. Dis , vol.11 , pp. 210-215
    • Liem, N.T.1    Lim, W.2
  • 69
    • 29644443464 scopus 로고    scopus 로고
    • Seroprevalence of anti-H5 antibody among Thai health care workers after exposure to avian influenza (H5N1) in a tertiary care center
    • Apisarnthanarak A, Erb S, Stephenson I et al.: Seroprevalence of anti-H5 antibody among Thai health care workers after exposure to avian influenza (H5N1) in a tertiary care center. Clin. Infect. Dis. 40, E16-E18 (2005).
    • (2005) Clin. Infect. Dis , vol.40
    • Apisarnthanarak, A.1    Erb, S.2    Stephenson, I.3
  • 70
    • 0034486618 scopus 로고    scopus 로고
    • Hemophagocytic syndromes and infection
    • Fisman DN: Hemophagocytic syndromes and infection. Emerg. Infect. Dis. 6, 601-608 (2000).
    • (2000) Emerg. Infect. Dis , vol.6 , pp. 601-608
    • Fisman, D.N.1
  • 71
    • 28044445881 scopus 로고    scopus 로고
    • Proinflammatory cytokine responses induced by influenza A (H5N1) viruses in primary human alveolar and bronchial epithelial cells
    • Chan MC, Cheung CY, Chui WH et al.: Proinflammatory cytokine responses induced by influenza A (H5N1) viruses in primary human alveolar and bronchial epithelial cells. Respir. Res. 6, 135 (2005).
    • (2005) Respir. Res , vol.6 , pp. 135
    • Chan, M.C.1    Cheung, C.Y.2    Chui, W.H.3
  • 73
    • 23244461479 scopus 로고    scopus 로고
    • p38 mitogen-activated protein kinase-dependent hyperinduction of tumor necrosis factor α expression in response to avian influenza virus H5N1
    • Lee DC, Cheung CY, Law AH, Mok CK, Peiris M, Lau AS: p38 mitogen-activated protein kinase-dependent hyperinduction of tumor necrosis factor α expression in response to avian influenza virus H5N1. J. Virol. 79, 10147-10154 (2005).
    • (2005) J. Virol , vol.79 , pp. 10147-10154
    • Lee, D.C.1    Cheung, C.Y.2    Law, A.H.3    Mok, C.K.4    Peiris, M.5    Lau, A.S.6
  • 74
    • 55549130267 scopus 로고    scopus 로고
    • Gene expression analysis of host innate immune responses during lethal H5N1 infection in ferrets
    • Cameron CM, Cameron MJ, Bermejo-Martin JF et al.: Gene expression analysis of host innate immune responses during lethal H5N1 infection in ferrets. J. Virol. 82, 11308-11317 (2008).
    • (2008) J. Virol , vol.82 , pp. 11308-11317
    • Cameron, C.M.1    Cameron, M.J.2    Bermejo-Martin, J.F.3
  • 75
    • 48749089085 scopus 로고    scopus 로고
    • Hyperinduction of cyclooxygenase-2-mediated proinflammatory cascade: A mechanism for the pathogenesis of avian influenza H5N1 infection
    • Lee SM, Cheung CY, Nicholls JM et al.: Hyperinduction of cyclooxygenase-2-mediated proinflammatory cascade: a mechanism for the pathogenesis of avian influenza H5N1 infection. J. Infect. Dis. 198, 525-535 (2008).
    • (2008) J. Infect. Dis , vol.198 , pp. 525-535
    • Lee, S.M.1    Cheung, C.Y.2    Nicholls, J.M.3
  • 76
    • 45849109558 scopus 로고    scopus 로고
    • Delayed antiviral plus immunomodulator treatment still reduces mortality in mice infected by high inoculum of influenza A/H5N1 virus
    • Zheng BJ, Chan KW, Lin YP et al.: Delayed antiviral plus immunomodulator treatment still reduces mortality in mice infected by high inoculum of influenza A/H5N1 virus. Proc. Natl Acad. Sci. USA 105, 8091-8096 (2008).
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 8091-8096
    • Zheng, B.J.1    Chan, K.W.2    Lin, Y.P.3
  • 77
    • 55549137723 scopus 로고    scopus 로고
    • Role of hypercytokinemia in NF-κB p50-deficient mice aftet H5N1 influenza A virus infection
    • Droebner K, Reiling SJ, Planz O: Role of hypercytokinemia in NF-κB p50-deficient mice aftet H5N1 influenza A virus infection. J. Virol. 82, 11461-11466 (2008).
    • (2008) J. Virol , vol.82 , pp. 11461-11466
    • Droebner, K.1    Reiling, S.J.2    Planz, O.3
  • 78
    • 0028847292 scopus 로고
    • Binding of the influenza virus NS1 protein to double-stranded RNA inhibits the activation of the protein kinase that phosphorylates the elF-2 translation initiation factor
    • Lu Y, Wambach M, Katze MG, Krug RM: Binding of the influenza virus NS1 protein to double-stranded RNA inhibits the activation of the protein kinase that phosphorylates the elF-2 translation initiation factor. Virology 214, 222-228 (1995).
    • (1995) Virology , vol.214 , pp. 222-228
    • Lu, Y.1    Wambach, M.2    Katze, M.G.3    Krug, R.M.4
  • 79
    • 33646517711 scopus 로고    scopus 로고
    • Binding of the influenza A virus NS1 protein to PKR mediates the inhibition of its activation by either PACT or double-stranded RNA
    • Li S, Min JY, Krug RM, Sen GC: Binding of the influenza A virus NS1 protein to PKR mediates the inhibition of its activation by either PACT or double-stranded RNA. Virology 349(1), 13-21 (2006).
    • (2006) Virology , vol.349 , Issue.1 , pp. 13-21
    • Li, S.1    Min, J.Y.2    Krug, R.M.3    Sen, G.C.4
  • 80
    • 41949123710 scopus 로고    scopus 로고
    • A new influenza virus virulence determinant: The NS1 protein four C-terminal residues modulate pathogenicity
    • Jackson D, Hossain MJ, Hickman D, Perez DR, Lamb RA: A new influenza virus virulence determinant: the NS1 protein four C-terminal residues modulate pathogenicity. Proc. Natl Acad. Sci. USA 105, 4381-4386 (2008).
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 4381-4386
    • Jackson, D.1    Hossain, M.J.2    Hickman, D.3    Perez, D.R.4    Lamb, R.A.5
  • 81
    • 33645067624 scopus 로고    scopus 로고
    • Large-scale sequence analysis of avian influenza isolates
    • Obenauer JC, Denson J, Mehra PK et al.: Large-scale sequence analysis of avian influenza isolates. Science 311, 1576-1580 (2006).
    • (2006) Science , vol.311 , pp. 1576-1580
    • Obenauer, J.C.1    Denson, J.2    Mehra, P.K.3
  • 82
    • 38349180176 scopus 로고    scopus 로고
    • A single-amino-acid substitution in the NS1 protein changes the pathogenicity of H5N1 avian influenza viruses in mice
    • Jiao P, Tian G, Li Y et al.: A single-amino-acid substitution in the NS1 protein changes the pathogenicity of H5N1 avian influenza viruses in mice. J. Virol. 82, 1146-1154 (2008).
    • (2008) J. Virol , vol.82 , pp. 1146-1154
    • Jiao, P.1    Tian, G.2    Li, Y.3
  • 83
    • 0141893997 scopus 로고    scopus 로고
    • Influenza virus induction of apoptosis by intrinsic and extrinsic mechanisms
    • Lowy RJ: Influenza virus induction of apoptosis by intrinsic and extrinsic mechanisms. Int. Rev. Immunol. 22, 425-449 (2003).
    • (2003) Int. Rev. Immunol , vol.22 , pp. 425-449
    • Lowy, R.J.1
  • 84
    • 0035658084 scopus 로고    scopus 로고
    • A novel influenza A virus mitochondrial protein that induces cell death
    • Chen W, Calvo PA, Malide D et al.: A novel influenza A virus mitochondrial protein that induces cell death. Nat. Med. 7, 1306-1312 (2001).
    • (2001) Nat. Med , vol.7 , pp. 1306-1312
    • Chen, W.1    Calvo, P.A.2    Malide, D.3
  • 85
    • 77951059450 scopus 로고    scopus 로고
    • Influenza virus PB1-F2 protein induces cell death through mitochondrial ANT3 and VDAC1
    • Zamarin D, Garcia-Sastre A, Xiao X, Wang R, Palese P: Influenza virus PB1-F2 protein induces cell death through mitochondrial ANT3 and VDAC1. PLoS Pathog. 1, e4 (2005).
    • (2005) PLoS Pathog , vol.1
    • Zamarin, D.1    Garcia-Sastre, A.2    Xiao, X.3    Wang, R.4    Palese, P.5
  • 86
    • 2642542356 scopus 로고    scopus 로고
    • PB1-F2, an influenza A virus-encoded proapoptotic mitochondrial protein, creates variably sized pores in planar lipid membranes
    • Chanturiya AN, Basanez G, Schubert U, Henklein P, Yewdell JW, Zimmerberg J: PB1-F2, an influenza A virus-encoded proapoptotic mitochondrial protein, creates variably sized pores in planar lipid membranes. J. Virol. 78, 6304-6312 (2004).
    • (2004) J. Virol , vol.78 , pp. 6304-6312
    • Chanturiya, A.N.1    Basanez, G.2    Schubert, U.3    Henklein, P.4    Yewdell, J.W.5    Zimmerberg, J.6
  • 87
    • 0038001672 scopus 로고    scopus 로고
    • The influenza A virus PB1-F2 protein targets the inner mitochondrial membrane via a predicted basic amphipathic helix that disrupts mitochondrial function
    • Gibbs JS, Malide D, Hornung F, Bennink JR, Yewdell JW: The influenza A virus PB1-F2 protein targets the inner mitochondrial membrane via a predicted basic amphipathic helix that disrupts mitochondrial function. J. Virol. 77, 7214-7224 (2003).
    • (2003) J. Virol , vol.77 , pp. 7214-7224
    • Gibbs, J.S.1    Malide, D.2    Hornung, F.3    Bennink, J.R.4    Yewdell, J.W.5
  • 88
    • 36049034216 scopus 로고    scopus 로고
    • A single mutation in the PB1-F2 of H5N1 (HK/97) and 1918 influenza A viruses contributes to increased virulence
    • Conenello GM, Zamarin D, Perrone LA, Tumpey T, Palese P: A single mutation in the PB1-F2 of H5N1 (HK/97) and 1918 influenza A viruses contributes to increased virulence. PLoS Pathog. 3, 1414-1421 (2007).
    • (2007) PLoS Pathog , vol.3 , pp. 1414-1421
    • Conenello, G.M.1    Zamarin, D.2    Perrone, L.A.3    Tumpey, T.4    Palese, P.5
  • 89
    • 0028049687 scopus 로고
    • Molecular and cellular processing of lung surfactant
    • Rooney SA, Young SL, Mendelson CR: Molecular and cellular processing of lung surfactant. Faseb J. 8, 957-967 (1994).
    • (1994) Faseb J , vol.8 , pp. 957-967
    • Rooney, S.A.1    Young, S.L.2    Mendelson, C.R.3
  • 90
    • 42149098369 scopus 로고    scopus 로고
    • The proapoptotic influenza A virus protein PB1-F2 regulates viral polymerase activity by interaction with the PB1 protein
    • Mazur I, Anhlan D, Mitzner D, Wixler L, Schubert U, Ludwig S: The proapoptotic influenza A virus protein PB1-F2 regulates viral polymerase activity by interaction with the PB1 protein. Cell. Microbiol. 10, 1140-1152 (2008).
    • (2008) Cell. Microbiol , vol.10 , pp. 1140-1152
    • Mazur, I.1    Anhlan, D.2    Mitzner, D.3    Wixler, L.4    Schubert, U.5    Ludwig, S.6
  • 92
    • 33751083554 scopus 로고    scopus 로고
    • Haemagglutinin mutations responsible for the binding of H5N1 influenza A viruses to human-type receptors
    • Yamada S, Suzuki Y, Suzuki T et al.: Haemagglutinin mutations responsible for the binding of H5N1 influenza A viruses to human-type receptors. Nature 444, 378-382 (2006).
    • (2006) Nature , vol.444 , pp. 378-382
    • Yamada, S.1    Suzuki, Y.2    Suzuki, T.3
  • 93
    • 35348895001 scopus 로고    scopus 로고
    • An avian influenza H5N1 virus that binds to a human-type receptor
    • Auewarakul P, Suptawiwat O, Kongchanagul A et al.: An avian influenza H5N1 virus that binds to a human-type receptor. J. Virol. 81, 9950-9955 (2007).
    • (2007) J. Virol , vol.81 , pp. 9950-9955
    • Auewarakul, P.1    Suptawiwat, O.2    Kongchanagul, A.3
  • 94
    • 23844436610 scopus 로고    scopus 로고
    • Strategies for containing an emerging influenza pandemic in Southeast Asia
    • Ferguson NM, Cummings DA, Cauchemez S et al.: Strategies for containing an emerging influenza pandemic in Southeast Asia. Nature 437,209-214 (2005).
    • (2005) Nature , vol.437 , pp. 209-214
    • Ferguson, N.M.1    Cummings, D.A.2    Cauchemez, S.3
  • 95
    • 23644457957 scopus 로고    scopus 로고
    • Containing pandemic influenza at the source
    • Longini IM Jr, Nizam A, Xu S et al.: Containing pandemic influenza at the source. Science 309, 1083-1087 (2005).
    • (2005) Science , vol.309 , pp. 1083-1087
    • Longini Jr, I.M.1    Nizam, A.2    Xu, S.3
  • 96
    • 33845641295 scopus 로고    scopus 로고
    • Estimation of potential global pandemic influenza mortality on the basis of vital. registry data from the 1918-1920 pandemic: A quantitative analysis
    • Murray CJ, Lopez AD, Chin B, Feehan D, Hill KH: Estimation of potential global pandemic influenza mortality on the basis of vital. registry data from the 1918-1920 pandemic: a quantitative analysis. Lancet 368, 2211-2218 (2006).
    • (2006) Lancet , vol.368 , pp. 2211-2218
    • Murray, C.J.1    Lopez, A.D.2    Chin, B.3    Feehan, D.4    Hill, K.H.5
  • 97
    • 50149111585 scopus 로고    scopus 로고
    • Factors associated with case fatality of human H5N1 virus infections in Indonesia: A case series
    • Kandun IN, Tresnaningsih E, Purba WH et al.: Factors associated with case fatality of human H5N1 virus infections in Indonesia: a case series. Lancet 372, 744-749 (2008).
    • (2008) Lancet , vol.372 , pp. 744-749
    • Kandun, I.N.1    Tresnaningsih, E.2    Purba, W.H.3
  • 98
    • 3142579867 scopus 로고    scopus 로고
    • Genesis of a highly pathogenic and potentially pandemic H5N1 influenza virus in eastern Asia
    • Li KS, Guan Y, Wang J et al.: Genesis of a highly pathogenic and potentially pandemic H5N1 influenza virus in eastern Asia. Nature 430, 209-213 (2004).
    • (2004) Nature , vol.430 , pp. 209-213
    • Li, K.S.1    Guan, Y.2    Wang, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.