Aluminium-induced oxidative DNA damage recognition and cell-cycle disruption in different regions of rat brain

Toxicology

Volumn 264, Issue 3, 2009, Pages 137-144

  Kumar, Vijay ^a   Bal, Amanjit ^a   Gill, Kiran Dip ^a  

^a POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH   (India)

Author keywords

8 Hydoxy 2 deoxyguanosine; Aluminium; Cell cycle proteins; DNA damage; Reactive oxygen species

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ALUMINUM LACTATE; CYCLIN D1; MESSENGER RNA; MITOCHONDRIAL DNA; PROTEIN P53;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN TOXICITY; CELL CYCLE ARREST; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; DNA DAMAGE; DNA FRAGMENTATION; DNA ISOLATION; GENE EXPRESSION; LONG TERM EXPOSURE; MALE; NERVE DEGENERATION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT;

ALUMINUM COMPOUNDS; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; BRAIN; CELL CYCLE; CEREBRAL CORTEX; CORPUS STRIATUM; CYCLIN D1; DEOXYGUANOSINE; DNA DAMAGE; DNA FRAGMENTATION; DNA, MITOCHONDRIAL; ELECTROPHORESIS, AGAR GEL; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; INTUBATION, GASTROINTESTINAL; LACTATES; MALE; NEURODEGENERATIVE DISEASES; OXIDATIVE STRESS; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR SUPPRESSOR PROTEIN P53;

RATTUS;

EID: 70349194352     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2009.05.011     Document Type: Article

References (45)

1. Arendt T. Dysregulation of neuronal differentiation and cell cycle control in Alzheimer's disease. J. Neural Transm. 62 (2002) 77-85
2. Becker E.B., and Bonni A. Cell cycle regulation of neuronal apoptosis in development and disease. Prog. Neurobiol. 72 (2004) 1-25
3. Bowser R., and Smith M.A. Cell cycle proteins in Alzheimer's disease: plenty of wheels but no cycle. J. Alzheimer Dis. 4 (2002) 249-254
4. Caspari T. How to activate p53. Curr. Biol. 10 (2000) R315-R317
5. Chandel N.S., Vander Heiden M.G., Thompson C.B., and Schumacker P.T. Redox regulation of p53 during hypoxia. Oncogene 19 (2000) 3840-3848
6. Chellappan S., Kraus V., Droger B., Munger K., Howley P., Phelps W., and Nevins J. Adenovirus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the retinoblastoma gene product. Proc. Natl. Acad. Sci. U.S.A. 89 (1992) 4549-4553
7. Chellappan S.P., Hiebert S., Mudry M., Horewitz J.M., and Nevins J.R. The E2F transcription factor is a cellular target for the RB protein. Cell 65 (1991) 1053-1061
8. Cooke M.S., Evan M.D., Dizdarogev R.J., and Wine C.J. Oxidative DNA damage: mechanisms, mutation and disease. FASEB J. 17 (2003) 1195-1214
9. Di Giovanni S., Movsesyan V., Ahmed F., Cernak I., Schinelli S., Stoica B., and Faden A.I. Cell cycle inhibition provides neuroprotection and reduces glial proliferation and scar formation after traumatic brain injury. Proc. Natl. Acad. Sci. U.S.A. 102 (2005) 8333-8338
10. Dizdaroglu M., Jaruga P., Birinciogev M., and Rodriguez H. Free radical-induced damage to DNA: mechanisms and measurement. Free Radic. Biol. Med. 32 (2000) 1102-1115
11. Farnham P., Slansky J., and Kollmar R. The role of E2F in the mammalian cell cycle. Biochim. Biophys. Acta 1155 (1993) 125-131
12. Glowinski J., and Iversen L.L. Regional studies of catecholamines in the rat brain. J. Neurochem. 13 (1966) 655-669
13. Halliwell B. Oxidative stress and neurodegeneration: where are we now?. J. Neurochem. 97 (2006) 1634-1658
14. Harrington E.A., Bruce J.L., Harlow E., and Dyson N. pRB plays an essential role in cell cycle arrest induced by DNA damage. Proc. Natl. Acad. Sci. U.S.A. 95 (1998) 11945-11950
15. Herbert K.E., Evan M.D., Finnegan M.T., Farooq S., Mistry N., Podmore I.D., Farmer P., and Lunec J. A novel HPLC procedure for the analysis of 8-oxoguanine in DNA. Free Radic. Biol. Med. 20 (1996) 467-472
16. Herrmann M., Lorenz H.M., Voll R., Grunke M., Woith W., and Xalden J.R. A Rapid and simple method for the isolation of apoptotic DNA fragments. Nucleic Acid Res. 22 (1994) 5506-5507
17. Hiyama H., and Reeves S.A. Role for cyclin D1 in UVC induced and p53-mediated apoptosis. Cell Death Differ. 6 (1999) 565-569
18. Holley A.K., and St Clair D.K. Watching the watcher: regulation of p53 by mitochondria. Future Oncol. 5 (2009) 117-130
19. Honma H., Gross L., and Windebank A.J. Hypoxia-induced apoptosis of dorsal root ganglion neurons is associated with DNA damage recognition and cell cycle disruption in rats. Neurosci. Lett. 354 (2004) 95-98
20. Hughes P.E., Alexi T., and Schreiber S.S. A role for the tumour suppressor gene p53 in regulating neuronal apoptosis. Neuroreport 8 (1997) v-xii
21. Julka D., Sandhir R., and Gill K.D. Altered cholinergic metabolism in rat CNS following aluminum exposure: implications on learning performance. J. Neurochem. 65 (1995) 2157-2164
22. Kaur A., Joshi K., Walker R.M., and Gill K.D. Neurofilament phosphorylation and disruption: a possible mechanism of chronic aluminium toxicity in Wistar rats. Toxicology 219 (2006) 1-10
23. Knudsen K.E., Booth D., Naderi S., Sever-Chroneos Z., Fribourg A.F., Hunton I., Feramisco J.R., Wang J.Y.J., and Knudsen E.S. Rb-dependent S-phase response to DNA damage. Mol. Cell Biol. 20 (2000) 7751-7763
24. Kranenburg O., Van der Eb A.J., and Zantema A. Cyclin D1 is an essential mediator of apoptotic neuronal cell death. EMBO J. 15 (1996) 46-54
25. Kumar V., Bal A., and Gill K.D. Impairment of mitochondrial energy metabolism in different regions of rat brain following chronic exposure to aluminium. Brain Res. 1232 (2008) 94-103
26. Kumar V., Bal A., and Gill K.D. Susceptibility of mitochondrial superoxide dismutase to aluminium induced oxidative damage. Toxicology 255 (2009) 117-123
27. Langley B., and Ratan R.R. Oxidative stress-induced death in the nervous system: cell cycle dependent or independent?. J. Neurosci. Res. 77 (2004) 621-629
28. Li J.M., and Shah A.M. Endothelial cell superoxide generation: regulation and relevance for cardiovascular pathophysiology. Am. J. Physiol. Regul. Integr. Comp. Physiol. 287 (2004) 1014-1030
29. Li Y., Jiang N., Powers C., and Chopp M. Neuronal damage and plasticity identified by microtubule-associated protein 2, growth-associated protein 43, and cyclin D1 immunoreactivity after focal cerebral ischemia in rats. Stroke 29 (1998) 1972-1981
30. Liang F.Q., and Godley B.F. Oxidative stress-induced mitochondrial DNA damage in human retinal pigment epithelial cells: a possible mechanism for RPE aging and age-related macular degeneration. Exp. Eye Res. 76 (2003) 397-403
31. Liu W., Bi X.N., Tocco G., Baudry M., and Schreiber S.S. Increased expression of cyclin D1 in the adult rat brain following kainic acid treatment. Neuroreport 7 (1996) 2785-2789
32. Lowry O.H., Rosebrough N.J., Farr A.L., and Randall R.J. Protein measurement with the folin-phenol reagent. J. Biol. Chem. 193 (1951) 265-275
33. Mecocci P., MacGarvey U., and Beal M.F. Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease. Ann. Neurol. 36 (1994) 747-751
34. Merino J.J., and Cordero-Campana M.I. Molecular bases of the programmed cell death process: Implications of tumor suppressor protein p53 and other proteins in the control of cell cycle. Mechanisms of apoptotic action. Rev. J. Clin. Invest. 39 (1998) 323-358
35. Nevins J. E2F: a link between the Rb tumor suppressor protein and viral oncoproteins. Science 258 (1992) 424-429
36. Niu P.Y., Niu Q., Zhang Q.L., Wang L.P., He S.E., and Wu T.C. Aluminium impairs rat neural cell mitochondria in vitro. Int. J. Immunopathol. Pharmacol. 18 (2005) 683-689
37. Raina A.K., Zhu X., Rottkamp C.A., Monteiro M., Takeda A., and Smith M.A. Cyclin' toward dementia: cell cycle abnormalities and abortive oncogenesis in Alzheimer disease. J. Neurosci. Res. 61 (2000) 128-133
38. Raina A.K., Zhu X., and Smith M.A. Alzheimer's disease and the cell cycle. Acta Neurobiol. Exp. (Wars) 64 (2004) 107-112
39. Ratan R.R., Murphy T.H., and Baraban J.M. Oxidative stress induced apoptosis in embryonic cortical neurons. J. Neurochem. 62 (1994) 376-379
40. Ryan K.M., Phillips A.C., and Vousden K.H. Regulation and function of the p53 tumor suppressor protein. Curr. Opin. Cell Biol. 13 (2001) 332-337
41. Smith R.A., Walker T., Xie X., and Hou S.T. Involvement of the transcription factor E2F1/Rb in kainic acid-induced death of murine cerebellar granule cells. Mol. Brain Res. 116 (2003) 70-79
42. Stevens C., and La Thangue N.B. The emerging role of E2F-1 in the DNA damage response and checkpoint control. DNA Repair 3 (2004) 1071-1079
43. Timsit S., Rivera S., Guischard F., Tremblay E., Ben-Ari Y., and Khrestchatisky M. Increased cyclin D1 in vulnerable neurons in the hippocampus after ischaemia and epilepsy: a modulator of in vivo programmed cell death?. Eur. J. Neurosci. 11 (1999) 263-278
44. Van Houten B., Woshner V., and Santos J.H. Role of mitochondrial DNA in toxic responses to oxidative stress. DNA Repair 5 (2006) 145-152
45. Yanagawa H., Ogawa Y., and Ueno N. Redox ribonucleosides. Isolation and characterization of 5-hydroxyuridine, 8-hydroxyguanosine and 8-hydroxyadenosine from Torula yeast RNA. J. Biol. Chem. 19 (1992) 13320-13326